Gene Ontology: phagocytosis

phagocytosis (GO:0006909):   An endocytosis process that results in the engulfment of external particulate material by phagocytes. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles. (biological_process ontology).

Use to view gene products from Dictyostelium and other species annotated to this GO term as well as to browse the gene ontology.

38 Dictyostelium genes/features have been directly annotated to the term phagocytosis
3 Dictyostelium genes/features have been directly annotated to NOT a phagocytosis , the negated form of the term phagocytosis

List of 38 genes/features directly annotated to the term phagocytosis
Gene	Reference(s)	Evidence
aip1	Konzok, Weber, Simmeth, Hacker, Maniak & Muller-Taubenberger (1999) ' DAip1, a Dictyostelium homologue of the yeast actin-interacting protein 1, is involved in endocytosis, cytokinesis, and motility. ' J Cell Biol 146 453-64	IMP
alyA	Muller, Subert, Otto, Herbst, Ruhling, Maniak & Leippe (2005) ' A Dictyostelium mutant with reduced lysozyme levels compensates by increased phagocytic activity. ' J Biol Chem 280 10435-43	IMP
atg9	Tung, Unal, Ley, Pena, Tunggal, Noegel, Krut, Steinert & Eichinger (2010) ' Loss of Dictyostelium ATG9 results in a pleiotropic phenotype affecting growth, development, phagocytosis and clearance and replication of Legionella pneumophila. ' Cell Microbiol 12 765-80	IMP
cbfA	Winckler, Trautwein, Tschepke, Neuhauser, Zundorf, Beck, Vogel & Dingermann (2001) ' Gene function analysis by amber stop codon suppression: CMBF is a nuclear protein that supports growth and development of Dictyostelium amoebae. ' J Mol Biol 305 703-14	IMP
cdk5	Sharma, Brock, Ammann, DeShazo, Khosla, Gomer & Weeks (2002) ' The cdk5 homologue, crp, regulates endocytosis and secretion in dictyostelium and is necessary for optimum growth and differentiation. ' Dev Biol 247 1-10	IMP
corB	Shina, Unal, Eichinger, Muller-Taubenberger, Schleicher, Steinert & Noegel (2010) ' A Coronin7 homolog with functions in actin-driven processes. ' J Biol Chem 285 9249-61	IMP
cshA	Huang, Chen, Lo, Liu, Wang & Chang (2004) ' Disruption of the peroxisomal citrate synthase CshA affects cell growth and multicellular development in Dictyostelium discoideum. ' Mol Microbiol 53 81-91	IMP
drkC	Fang, Brzostowski, Ou, Isik, Nair & Jin (2007) ' A vesicle surface tyrosine kinase regulates phagosome maturation. ' J Cell Biol 178 411-23	IMP
elmoB	DDB, FB, MGI, GOA & ZFIN curator (2001) ' Gene Ontology annotation through association of InterPro records with GO terms '	IEA
elmoC	DDB, FB, MGI, GOA & ZFIN curator (2001) ' Gene Ontology annotation through association of InterPro records with GO terms '	IEA
elmoD	DDB, FB, MGI, GOA & ZFIN curator (2001) ' Gene Ontology annotation through association of InterPro records with GO terms '	IEA
elmoE	DDB, FB, MGI, GOA & ZFIN curator (2001) ' Gene Ontology annotation through association of InterPro records with GO terms '	IEA
elmoF	DDB, FB, MGI, GOA & ZFIN curator (2001) ' Gene Ontology annotation through association of InterPro records with GO terms '	IEA
gefB	Wilkins, Chubb & Insall (2000) ' A novel Dictyostelium RasGEF is required for normal endocytosis, cell motility and multicellular development. ' Curr Biol 10 1427-37	IMP
lvsA	Cornillon, Dubois, Bruckert, Lefkir, Marchetti, Benghezal, De Lozanne, Letourneur & Cosson (2002) ' Two members of the beige/CHS (BEACH) family are involved at different stages in the organization of the endocytic pathway in Dictyostelium. ' J Cell Sci 115 737-44	IMP
midA	Torija, Vicente, Rodrigues, Robles, Cerdan, Sastre, Calvo & Escalante (2006) ' Functional genomics in Dictyostelium: MidA, a new conserved protein, is required for mitochondrial function and development. ' J Cell Sci 119 1154-64	IMP
myoB	Jung, Wu & Hammer (1996) ' Dictyostelium mutants lacking multiple classic myosin I isoforms reveal combinations of shared and distinct functions. ' J Cell Biol 133 305-23	IMP
myoC	Jung, Wu & Hammer (1996) ' Dictyostelium mutants lacking multiple classic myosin I isoforms reveal combinations of shared and distinct functions. ' J Cell Biol 133 305-23	IMP
myoE	Durrwang, Fujita-Becker, Erent, Kull, Tsiavaliaris, Geeves & Manstein (2006) ' Dictyostelium myosin-IE is a fast molecular motor involved in phagocytosis. ' J Cell Sci 119 550-8	IMP
myoI	Titus (1999) ' A class VII unconventional myosin is required for phagocytosis. ' Curr Biol 9 1297-303	IMP
	Gebbie, Benghezal, Cornillon, Froquet, Cherix, Malbouyres, Lefkir, Grangeasse, Fache, Dalous, Bruckert, Letourneur & Cosson (2004) ' Phg2, a kinase involved in adhesion and focal site modeling in Dictyostelium. ' Mol Biol Cell 15 3915-25	IMP
nramp1	Peracino, Wagner, Balest, Balbo, Pergolizzi, Noegel, Steinert & Bozzaro (2006) ' Function and mechanism of action of Dictyostelium Nramp1 (Slc11a1) in bacterial infection. ' Traffic 7 22-38	IEP
nsfA	Thompson & Bretscher (2002) ' Cell polarity and locomotion, as well as endocytosis, depend on NSF. ' Development 129 4185-92	IMP
pakA	Manahan, Iglesias, Long & Devreotes (2004) ' Chemoattractant signaling in dictyostelium discoideum. ' Annu Rev Cell Dev Biol 20 223-53	TAS
phg1a	Benghezal, Cornillon, Gebbie, Alibaud, Bruckert, Letourneur & Cosson (2003) ' Synergistic control of cellular adhesion by transmembrane 9 proteins. ' Mol Biol Cell 14 2890-9	IMP
phg1b	Benghezal, Cornillon, Gebbie, Alibaud, Bruckert, Letourneur & Cosson (2003) ' Synergistic control of cellular adhesion by transmembrane 9 proteins. ' Mol Biol Cell 14 2890-9	IMP
phg1c	Weijer (2004) ' Dictyostelium morphogenesis. ' Curr Opin Genet Dev 14 392-8	TAS
phg2	Gebbie, Benghezal, Cornillon, Froquet, Cherix, Malbouyres, Lefkir, Grangeasse, Fache, Dalous, Bruckert, Letourneur & Cosson (2004) ' Phg2, a kinase involved in adhesion and focal site modeling in Dictyostelium. ' Mol Biol Cell 15 3915-25	IMP
ppk1	Zhang, Gomez-Garcia, Brown & Kornberg (2005) ' Inorganic polyphosphate in Dictyostelium discoideum: influence on development, sporulation, and predation. ' Proc Natl Acad Sci U S A 102 2731-5	IMP
rab7A	Laurent, Bruckert, Adessi & Satre (1998) ' In vitro reconstituted Dictyostelium discoideum early endosome fusion is regulated by Rab7 but proceeds in the absence of ATP-Mg2+ from the bulk solution. ' J Biol Chem 273 793-9	IMP
racG	Somesh, Vlahou, Iijima, Insall, Devreotes & Rivero (2006) ' RacG regulates morphology, phagocytosis, and chemotaxis. ' Eukaryot Cell 5 1648-63	IDA
racH	Somesh, Neffgen, Iijima, Devreotes & Rivero (2006) ' Dictyostelium RacH regulates endocytic vesicular trafficking and is required for localization of vacuolin. ' Traffic 7 1194-212	IMP
sadA	Fey, Stephens, Titus & Chisholm (2002) ' SadA, a novel adhesion receptor in Dictyostelium. ' J Cell Biol 159 1109-19	IMP
scrA	Cvrckova, Rivero & Bavlnka (2004) ' Evolutionarily conserved modules in actin nucleation: lessons from Dictyostelium discoideum and plants. Review article. ' Protoplasma 224 15-31	TAS
shkA	Moniakis, Funamoto, Fukuzawa, Meisenhelder, Araki, Abe, Meili, Hunter, Williams & Firtel (2001) ' An SH2-domain-containing kinase negatively regulates the phosphatidylinositol-3 kinase pathway. ' Genes Dev 15 687-98	IMP
sibA	Cornillon, Gebbie, Benghezal, Nair, Keller, Wehrle-Haller, Charette, Bruckert, Letourneur & Cosson (2006) ' An adhesion molecule in free-living Dictyostelium amoebae with integrin beta features. ' EMBO Rep 7 617-21	IMP
	Cornillon, Froquet & Cosson (2008) ' Involvement of Sib proteins in the regulation of cellular adhesion in Dictyostelium discoideum. ' Eukaryot Cell 7 1600-5	IMP
sibC	Cornillon, Froquet & Cosson (2008) ' Involvement of Sib proteins in the regulation of cellular adhesion in Dictyostelium discoideum. ' Eukaryot Cell 7 1600-5	IMP
talA	Niewohner, Weber, Maniak, Muller-Taubenberger & Gerisch (1997) ' Talin-null cells of Dictyostelium are strongly defective in adhesion to particle and substrate surfaces and slightly impaired in cytokinesis. ' J Cell Biol 138 349-61	IMP
	Gebbie, Benghezal, Cornillon, Froquet, Cherix, Malbouyres, Lefkir, Grangeasse, Fache, Dalous, Bruckert, Letourneur & Cosson (2004) ' Phg2, a kinase involved in adhesion and focal site modeling in Dictyostelium. ' Mol Biol Cell 15 3915-25	IMP
trrA	Jeong, Choi, Kim, Park & Kang (2006) ' Thioredoxin reductase is required for growth and regulates entry into culmination of Dictyostelium discoideum. ' Mol Microbiol 61 1443-56	IMP

List of 3 genes/features directly annotated to NOT a  phagocytosis the negated form of the term phagocytosis
Gene	Reference(s)	Evidence
chcA	O'Halloran & Anderson (1992) ' Clathrin heavy chain is required for pinocytosis, the presence of large vacuoles, and development in Dictyostelium. ' J Cell Biol 118 1371-7	IMP
lvsB	Cornillon, Dubois, Bruckert, Lefkir, Marchetti, Benghezal, De Lozanne, Letourneur & Cosson (2002) ' Two members of the beige/CHS (BEACH) family are involved at different stages in the organization of the endocytic pathway in Dictyostelium. ' J Cell Sci 115 737-44	IMP
torA	van Es, Wessels, Soll, Borleis & Devreotes (2001) ' Tortoise, a novel mitochondrial protein, is required for directional responses of Dictyostelium in chemotactic gradients. ' J Cell Biol 152 621-32	IMP