Dictyostelium Mutants

Phenotypes for Dictyostelium mutants

View other mutant types: All mutant strains - Null - Overexpression - Multiple - Other - Developmental

To view more details, including parent strains and references, click on the corresponding dictyBase ID.

Systematic Name	Strain Descriptor	Associated gene(s)	Phenotypes
DBS0266514	DDB_G0271714-/ DDB_G0271824-/ DDB_G0271716-/ DDB_G0271718-/ DDB_G0271822-/ DDB_G0271712-/ DDB_G0295685-/ DDB_G0271818-	DDB_G0271712 \| DDB_G0271714 \| DDB_G0271716 \| DDB_G0271718 \| DDB_G0271818 \| DDB_G0271822 \| DDB_G0271824 \| DDB_G0295685	wild type
DBS0266513	DDB_G0272654-/ DDB_G0273021-/ DDB_G0273023-/ DDB_G0272656-/ DDB_G0272658-/ DDB_G0272927-/ DDB_G0273025-	DDB_G0272654 \| DDB_G0272656 \| DDB_G0272658 \| DDB_G0272927 \| DDB_G0273021 \| DDB_G0273023 \| DDB_G0273025	wild type
DBS0266705	Dd5P1-/ Dd5P2-	Dd5P1 \| Dd5P2	wild type
DBS0266704	Dd5P1-/ Dd5P3-	Dd5P1 \| Dd5P3	wild type
DBS0266703	Dd5P2-/ Dd5P3-	Dd5P2 \| Dd5P3	wild type
DBS0236084	GP138A-/ GP138B-/ GP138C-/ GP138D-	cfrA \| cfrB \| cfrC \| cfrD	decreased gene expression
DBS0237228	[AS]GP138A/ [AS]GP138B	cfrA \| cfrB	decreased sexual fusion
DBS0236827	[AS]proA/ proB-	proA \| proB	increased basal F-actin level \| abolished growth \| development arrests at slug stage \| aberrant cytokinesis \| decreased cell motility
DBS0238036	[AS]proA/ proB-/ [act15]: proA	proA \| proB	wild type
DBS0238037	[AS]proA/ proB-/ [act15]: proB	proA \| proB	wild type
DBS0238035	[AS]proA/ proB-/ [unk]: FLAG: proC	proA \| proB \| proC	wild type
DBS0302610	[OE]: disgorgin/ phgA-	DDB_G0280955 \| phgA	aberrant contractile vacuole organization and biogenesis
DBS0302611	[OE]: phgA/ disgorgin-	DDB_G0280955 \| phgA	aberrant contractile vacuole organization and biogenesis
DBS0302685	[OE]: sgcA(1-2000)(N1106A): GFP/ gca-/ sgcA-	gcA \| sgcA	decreased chemotaxis rate
DBS0302683	[OE]: sgcA(878-2843)(N1106A): GFP/ gca-/ sgcA-	gcA \| sgcA	decreased chemotaxis rate
DBS0302681	[OE]: sgcA(878-2843): GFP/ sgcA-	gcA \| sgcA	decreased chemotaxis rate
DBS0302682	[OE]: sgcA(N1106A): GFP/ gca-/ sgcA-	gcA \| sgcA	aberrant streaming \| increased lateral pseudopod formation \| decreased chemotaxis rate
DBS0302684	[OE]: sgcA: GFP/ gca-/ sgcA-	gcA \| sgcA	increased lateral pseudopod formation \| decreased chemotaxis rate
DBS0236539	abcG2-/ abcG18-	abcG18 \| abcG2	decreased rate of endocytosis \| abolished growth \| decreased growth rate
DBS0236540	abcG2-/ abcG18-/ rtoA-	abcG18 \| abcG2 \| rtoA	abolished growth \| decreased growth rate
DBS0266689	abiA-/ scrA-	abiA \| scrA	decreased cell motility \| decreased cell size
DBS0235456	abpA-/ abpC-	abpA \| abpC	aberrant response to hyperosmotic stress \| decreased phagocytosis \| decreased growth rate \| decreased cell motility \| aberrant development
DBS0235425	abpB-/ fimA-	abpB \| fimA	decreased fruiting body size \| decreased sporulation \| decreased cell size
DBS0306126	acapA-/ acapB-	acapA \| acapB	decreased sporulation
AK1211	acbA-/ tagA-	acbA \| tagA	increased prestalk B cell differentiation
BS165	amtA-/ amtC-	amtA \| amtC	aberrant slug migration \| decreased localization of protein to the nucleus \| delayed gene expression
BS163	amtC-/ dhkC-	amtC \| dhkC	mislocalized gene expression
DBS0236890	amtC-/ regA-	amtC \| regA	precocious sporulation
DBS0266655	atg1-/ iplA-	atg1 \| iplA	decreased necrotic cell death
DBS0252632	atg1-/ pcp-	atg1 \| pcp	abolished autophagic vacuole formation
RI4	carA-/ carC-	carA-1 \| carA-2 \| carC	decreased chemoattractant-mediated F-actin polymerization \| decreased cAMP-induced cGMP pulse \| abolished aggregation
DBS0235570	carB-	carB	development arrests at mound stage
TL53	cotA-/ cotB-	cotA \| cotB	aberrant spore coat morphology
TL56	cotA-/ cotB-/ cotC-	cotA \| cotB \| cotC	aberrant spore coat morphology
TL57	cotA-/ cotB-/ cotC-	cotA \| cotB \| cotC	aberrant spore coat morphology
TL54	cotB-/ cotC-	cotB \| cotC	aberrant spore coat morphology
HG1772	crtA-/ cnxA-	cnxA \| crtA	decreased growth rate in suspension \| delayed response to cAMP \| decreased extracellular Ca2+ uptake \| decreased phagocytosis \| increased cytosolic Ca2+ response \| decreased growth rate on bacterial plates
TL73	csaA-/ csbA-/ csbC-/ csbC-	csaA \| csbA \| csbB \| csbC	aberrant culminant morphology
TL72	csbA-/ csbB-/ csbC-	csbA \| csbB \| csbC	increased resistance to cisplatin \| aberrant culminant morphology
DBS0304928	ctnnA-/ mhcA-	ctnnA \| mhcA	aberrant cytokinesis
DBS0237568	ctxA-/ [RNAi]enlA	ctxA \| enlA	wild type
DBS0235599	ctxA-/ ctxB-	ctxA \| ctxB	aberrant regulation of Rap GTPase activity \| aberrant cytokinesis \| aberrant cell morphology
DBS0266760	culB-/ pkaR-	culB \| pkaR	abolished gene expression \| abolished sporulation \| precocious gene expression \| abolished aggregation
DBS0349807	detA-/ [act6]: GFP: detA	detA	wild type
DBS0349816	detA-/ [act6]: GFP: detA/ [act6]: 3xHA: culD	culD \| detA	increased gene expression
DBS0349817	detA-/ [act6]: GFP: detA/ [act6]: 3xHA: repE	detA \| repE	increased gene expression
TL134	dhkA-/ dhkB-	dhkA \| dhkB	abolished sporulation \| increased stalk length \| decreased stalk width
HR49	dhkA-/ fbxA-	dhkA \| fbxA	decreased intracellular cAMP level \| aberrant fruiting body morphology \| decreased sporulation
HR51	dhkA-/ fbxA-	dhkA \| fbxA	aberrant fruiting body morphology \| decreased sporulation
HR50	dhkA-/ fbxA-	dhkA \| fbxA	abolished culmination \| decreased sporulation
DBS0235714	dhkK-/ regA-	dhkK \| regA	precocious development
DBS0235899	dimA-/ dimB-	dimA \| dimB	thin fingers \| long fingers \| increased slug size
DBS0302608	disgorgin(1-571: 581-733)/ disgorgin-	DDB_G0280955	aberrant contractile vacuole organization and biogenesis \| aberrant cellular localization
DBS0302607	disgorgin-/ [OE]: lvsA	DDB_G0280955 \| lvsA	aberrant contractile vacuole organization and biogenesis
DBS0302606	disgorgin-/ [OE]: lvsD	DDB_G0280955 \| lvsD	wild type
DBS0302604	disgorgin-/ lvsA-	DDB_G0280955 \| lvsA	wild type
DBS0302605	disgorgin-/ lvsD-	DDB_G0280955 \| lvsD	aberrant contractile vacuole organization and biogenesis
HM1196	dmtA-/ stlA-	dmtA \| stlB	decreased outer basal disc size \| decreased prestalk O cell differentiation
HAD205	dpoA-/ gskA-	dpoA \| gskA	aberrant development
DBS0235927	dstA-/ dstB-	dstA \| dstB	wild type
DBS0235932	dstB-/ dstC-	dstB \| dstC	wild type
DBS0302598	elmoA-/ [act15]: elmoA(1-903/ 959-977): GFP	elmoA	decreased cell motility \| increased phagocytosis
DBS0302474	epnA-/ [act15]: epnA(R65A/ K78A): GFP	epnA	abolished localization of protein to the plasma membrane \| aberrant spore morphology \| abolished phosphatidylinositol-4,5-bisphosphate binding \| abolished localization of protein to coated pits
DBS0302475	epnA-/ [act15]: epnA(T107A): GFP	epnA	aberrant spore morphology
DBS0235949	erkB-/ regA-	erkB \| regA	increased cAMP-induced cAMP pulse \| abolished aggregation
HR46	fbxA-/ regA-	fbxA \| regA	aberrant fruiting body morphology \| decreased sporulation
HR48	fbxA-/ regA-	fbxA \| regA	aberrant fruiting body morphology \| decreased sporulation
HM1351	fncD2-/ rev3-	fncD2 \| rev3	increased sensitivity to cisplatin
HM1405	fncD2-/ xpf-	fncD2 \| xpf	increased sensitivity to cisplatin
DBS0235967	forA-/ forB-	forA \| forB	wild type
DBS0235978	fszA-/ fszB-	fszA \| fszB	increased number of tubular mitochondria
DBS0235992	gbpA-/ gbpB-	pdeD \| pdeE	increased myosin light chain kinase activation
DBS0235996	gbpC-/ gbpD-	gbpC \| gbpD	decreased cell polarity \| decreased chemotaxis rate
DBS0236000	gca-/ sgcA-	gcA \| sgcA	decreased myosin light chain kinase activation
DBS0302679	gca-/ sgcA-	gcA \| sgcA	aberrant streaming \| aberrant chemotaxis to cAMP \| increased lateral pseudopod formation \| decreased chemotaxis rate \| decreased aggregate size \| decreased fruiting body size
DBS0236095	gdt1-/ gpaB-	gdt1 \| gpaB	increased gene expression \| abolished aggregation
DBS0236010	gefB-/ rasS-	gefB \| rasS	decreased phagocytosis \| increased cell motility
DBS0238605	gpaA-/ rpkA-	gpaA \| rpkA	delayed aggregation \| abolished aggregation
DBS0236131	hbx2-/ warA-	hbx2 \| warA	increased basal disc size \| development arrests at mound stage \| decreased prespore cell differentiation \| increased prestalk O cell differentiation
DBS0305951	hipA-/ epnA-	epnA \| hipA	aberrant spore morphology \| decreased spore viability
BS161	ifkA-/ ifkB-	ifkA \| ifkB	increased aggregate size \| increased cell-cell adhesion \| increased cell-substrate adhesion \| aberrant fruiting body morphology \| multiple tips in mound
DBS0236729	limB-/ paxB-	limB \| paxB	development arrests at mound stage
DBS0238098	mekA-/ ppp4C-	mekA \| ppp4c	decreased aggregate size
DBS0238109	mekA-/ ppp4C-/ [act15]: FLAG: pppC	ppp4c	decreased aggregate size \| precocious development
DBS0236542	mekA-/ smkA-	mekA \| smkA	decreased aggregate size
DBS0237564	mhcA-/ [act15]: GFP: ctxA/ [RNAi]enlA	ctxA \| enlA \| mhcA	aberrant cytokinesis, contractile ring contraction
CW0431	mhkA-/ mhkB-/ mhkC-	mhkA \| mhkB \| mhkC	decreased growth rate in suspension \| increased myosin II assembly \| aberrant cytokinesis
DBS0236556	mhkA-/ mhkC-	mhkA \| mhkC	decreased growth rate in suspension \| increased myosin II assembly \| aberrant cytokinesis
CW0394	mhkA/ mhkB	mhkA \| mhkB	decreased growth rate in suspension \| increased myosin II assembly \| aberrant cytokinesis
DBS0309109	mipp1-/ dpoA-	dpoA \| mipp1	aberrant inositol phosphate metabolic process \| increased response to lithium
DBS0236561	mkcA-/ tagB-	mkcA \| tagB	decreased sporulation
DBS0236562	mkcA-/ tagC-	mkcA \| tagC	decreased sporulation
DBS0304881	mrps4-	mrps4	delayed aggregation
DBS0304882	mtDNA-	DidioMp05 \| DidioMp21 \| DidioMp26 \| DidioMp27 \| DidioMp30 \| DidioMp35 \| DidioMp36 \| ai2a \| ai2b \| ai3 \| ai4 \| atp1 \| atp6 \| atp9 \| cox1/ 2 \| cox3 \| cytB \| mrpl11 \| mrpl14 \| mrpl16 \| mrpl2 \| mrpl6 \| mrps12 \| mrps13 \| mrps14 \| mrps19 \| mrps2 \| mrps4 \| mrps7 \| mrps8 \| nad1 \| nad11 \| nad2 \| nad3 \| nad4 \| nad4L \| nad5 \| nad6 \| nad7 \| nad9 \| rnlA	abolished growth \| abolished aggregation
HDT5	myoA-/ myoB	myoA \| myoB	decreased pinocytosis \| decreased growth rate in suspension \| aberrant cytoskeleton organisation \| increased secretion of lysosomal enzyme \| decreased cell motility \| decreased fruiting body size
HDT6	myoB-/ myoC-	myoB \| myoC	increased secretion of lysosomal enzyme \| decreased growth rate in suspension \| aberrant cytoskeleton organisation \| decreased fruiting body size
SB14	napA-/ pirA-	napA \| pirA	decreased basal F-actin level
DBS0304634	nfaA-/ rasG-	nfaA \| rasG	decreased cell polarity
DBS0236610	noxA-/ noxB	noxA \| noxB	abolished sporulation \| decreased superoxide production \| aberrant development
DBS0306169	p2xA-/ p2xB-/ p2xC-/ p2xD-/ p2xE-	p2xA \| p2xB \| p2xC \| p2xD \| p2xE	delayed response to hypo-osmotic stress \| decreased growth rate
DBS0236715	pakB-/ pakC-	pakB \| pakC	decreased chemotaxis rate
DBS0304929	paxB-/ mhcA-	mhcA \| paxB	aberrant cytokinesis
DBS0236742	pefA-/ pefB-	pefA \| pefB	wild type
DBS0236745	pefB-/ cybA-	cybA \| pefB	wild type
DBS0236746	pefB-/ noxA-	noxA \| pefB	wild type
DBS0236747	pefB-/ noxA-/ [act15]: pefB	noxA \| pefB	aberrant development
DBS0236748	pefB-/ noxB-	noxB \| pefB	wild type
DBS0236749	pefB-/ noxC-	noxC \| pefB	abolished sporulation \| aberrant development
DBS0304869	phg1A-/ [act15]: phg1a(1-276): phg1b(221-587)	phg1a \| phg1b	decreased phagocytosis
DBS0304868	phg1A-/ [act15]: phg1b	phg1a \| phg1b	increased secretion of lysosomal enzyme \| decreased cell-substrate adhesion \| decreased phagocytosis
DBS0304870	phg1A-/ [act15]: phg1b(1-220): phg1a(277-642)	phg1a \| phg1b	decreased phagocytosis
DBS0304872	phg1A-/ phg1b-	phg1a \| phg1b	increased secretion of lysosomal enzyme \| decreased cell-substrate adhesion \| decreased phagocytosis \| decreased growth rate \| development arrests at tipped mound stage \| abolished culmination
DBS0236766	pikA-/ pikB-	pikA \| pikB	aberrant negative chemotaxis \| decreased cell motility \| decreased chemotaxis to folate \| decreased cAMP-induced cAMP pulse
DBS0236773	pikA-/ pikB-	pikA \| pikB	abolished CRAC localization to the plasma membrane \| increased intracellular cAMP level \| aberrant adaptation of adenylate cyclase \| abolished SDF production \| delayed aggregation \| abolished growth in suspension \| multiple tips \| abolished streaming \| decreased cAMP-induced cAMP pulse
HM1141	pikA-/ pikB-	pikA \| pikB	decreased cell motility
DBS0252703	pikA-/ pikB-/ pikC-	pikA \| pikB \| pikC	increased cell motility
HM1200	pikA-/ pikB-/ pikC-/ pikF-/ pikG-	pikA \| pikB \| pikC \| pikF \| pikG	aberrant aggregation \| decreased growth rate in bacterial suspension \| decreased protein tyrosine phosphorylation \| decreased cell motility
HM1284	pikA-/ pikB-/ pikC-/ pikF-/ pikG-/ pikH-	pikA \| pikB \| pikC \| pikF \| pikG \| pikH	decreased cell motility
HM1295	pikA-/ pikB-/ pikC-/ pikF-/ pikG-/ pten-	pikA \| pikB \| pikC \| pikF \| pikG \| pten	aberrant aggregation \| decreased growth rate \| decreased cell motility
DBS0238073	pikA-/ pikB-/ plaA-	pikA \| pikB \| plaA	decreased chemoattractant-mediated F-actin polymerization \| abolished chemotaxis \| delayed aggregation
DBS0236782	pkaC-/ gdt1-	gdt1 \| pkaC	increased gene expression \| abolished aggregation
DBS0236785	pkbA-/ pkgB-	pkbA \| pkgB	abolished growth \| decreased chemotaxis rate \| abolished aggregation
DBS0304640	pkbA-/ pkgB-	pkbA \| pkgB	abolished growth
DBS0236855	rasC-/ dmpA-	dmpA \| rasC	abolished streaming
DBS0236857	rasC-/ rasD-	rasC \| rasD	abolished aggregation
DBS0236858	rasC-/ rasG-	rasC \| rasG	decreased gene expression \| abolished growth \| abolished protein kinase B activation \| decreased growth rate \| decreased activation of adenylate cyclase \| decreased cell motility \| abolished aggregation \| delayed gene expression \| abolished chemotaxis to cAMP \| abolished GTP-gamma-S-stimulated guanylyl cyclase activity
DBS0266697	rasC-/ rasG-/ [act15]: carA	carA-1 \| carA-2 \| rasC \| rasG	abolished activation of Rap GTPase activity \| abolished growth \| decreased growth rate \| abolished protein kinase B activation \| decreased activation of adenylate cyclase \| abolished cAMP-induced cGMP pulse \| abolished chemotaxis to cAMP
DBS0236891	regA-/ tagB-	regA \| tagB	decreased sporulation
DBS0236892	regA-/ tagC-	regA \| tagC	decreased sporulation
DBS0349790	sadA-/ [act15]: sadA(1-923): GFP	sadA	decreased cell-substrate adhesion
DBS0349792	sadA-/ [act15]: sadA(S924A/ S925A): GFP	sadA	wild type
DBS0349791	sadA-/ [act15]: sadA(S924E/ S925E): GFP	sadA	decreased cell-substrate adhesion
SB18	scrA-/ napA-	napA \| scrA	decreased cell motility \| decreased basal F-actin level
SB7	scrA-/ pirA-	pirA \| scrA	decreased cell size
HM1093	sgkA-/ sgkB-	sgkA \| sgkB	increased sensitivity to cisplatin \| increased sensitivity to carboplatin \| decreased growth rate
DBS0302657	smlA-/ cnrN-	cnrN \| smlA	decreased fruiting body size
DBS0236940	smlA-/ ctnA-	ctnA \| smlA	increased cell-cell adhesion
DBS0304496	smlA-/ sslA1(CR11)	smlA \| sslA1	increased fruiting body size
DBS0236943	spkA-1-/ spkA-2-	spkA-1 \| spkA-2	decreased cell polarity \| decreased cell-substrate adhesion \| aberrant cytokinesis \| decreased chemotaxis rate \| decreased aggregate size \| aberrant cell morphology \| decreased fruiting body size
DBS0236944	spkA-1-/ spkA-2-/ [act15]: spkA: FLAG	spkA-1 \| spkA-2	aberrant aggregation \| decreased cell polarity \| aberrant F-actin organization \| decreased chemotaxis rate
DBS0236948	spnA-/ arkA-	arkA \| spnA	decreased gene expression \| increased sorus size \| decreased stalk length \| delayed gene expression
DBS0236974	tagB-/ psmA1-	psmA1 \| tagB	abolished sporulation
DBS0304581	talA-/ talB-	talA \| talB	development arrests at loose aggregate stage \| abolished cell-substrate adhesion \| aberrant cytokinesis \| abolished cell motility
JS64	tipA-/ tipB-/ [act15]: lacZ	tipA \| tipB	increased aggregate size \| development arrests at mound stage \| multiple tips in mound
JS98	tipA-/ tipC-/ [ecmA]: lacZ	tipA \| tipC	development arrests at loose aggregate stage
JS128	tipA-/ tipD-/ [ecmA]: lacZ	tipA \| tipD	development arrests at loose aggregate stage
JS99	tipB-/ tipC-/ [ecmA]: lacZ	tipB \| tipC	development arrests at tipped mound stage \| multiple tips in mound
JS129	tipB-/ tipD-/ [ecmA]: lacZ	tipB \| tipD	development arrests at tipped mound stage \| multiple tips in mound
JS130	tipC-/ tipD-/ [ecmA]: lacZ	tipC \| tipD	development arrests at loose aggregate stage
DBS0237050	warA-/ hbx2-	hbx2 \| warA	increased basal disc size \| development arrests at mound stage \| decreased prespore cell differentiation \| increased prestalk O cell differentiation
AK804	yakA-/ pufA-	pufA \| yakA	increased growth rate

Last updated January 28, 2012


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