To view more details, including parent strains and references, click on the corresponding dictyBase ID.
Systematic Name | Strain Descriptor | Associated gene(s) | Phenotypes |
---|---|---|---|
DBS0350195 | [act15]: acbA(Y72A) | acbA | decreased lipid binding |
DBS0350657 | [csaA]: csaA | csaA | aberrant aggregation | increased calcium-independent cell-cell adhesion |
DBS0350059 | mcln- | mcln | aberrant cellular response to fluid shear stress | increased growth rate | aberrant post-lysosomal vacuole exocytosis |
DBS0351382 | myoB-/ [act15]: GFP: myoB(1-921,1057-1111) | myoB | abolished protein localization to actin wave |
DBS0350826 | pinA- | pinA | decreased growth rate | decreased mound size | decreased sporulation |
DBS0235412 | 1C7 | gp130 | decreased cell-substrate adhesion | delayed development | increased growth rate |
DBS0238601 | 5NT- | 5nt | delayed development of tipped mound | increased number of mound tips | increased number of early culminant tips |
DBS0351520 | AK1334 | DDB_G0271574 | nip7 | decreased response to Gram-negative bacterium |
DBS0235584 | CF45-1- | cf45-1 | increased mound size | increased glucose level | decreased mound size | decreased cell motility | increased cell-cell adhesion |
DBS0235585 | CF50- | cf50-1 | cf50-2 | decreased response to Gram-negative bacterium | decreased response to Gram-positive bacterium | increased mound size | increased cell-cell adhesion | increased prespore gene expression | increased protein level | decreased protein secretion |
DBS0235594 | CHE10 | cbpC | decreased slug migration | precocious aggregation | decreased mound size | decreased fruiting body size | delayed culmination |
DBS0235595 | CHI2 | cbpC | increased slug migration |
DBS0235596 | ChLim- | ChLim | increased growth rate | increased phagocytosis |
DBS0351197 | D2B- | D2B | aberrant chemotaxis to cAMP |
DBS0235659 | DD3-3- | DD3-3 | decreased gene expression | precocious aggregation |
DBS0236049 | DDB_G0268012- | DDB_G0268012 | wild type |
DBS0236046 | DDB_G0268158- | DDB_G0268158 | wild type |
DBS0236039 | DDB_G0268678- | DDB_G0268678 | wild type |
DG1007 | DDB_G0269232- | DDB_G0269232 | abolished culmination |
DBS0236025 | DDB_G0270366- | DDB_G0270366 | wild type |
DBS0236026 | DDB_G0270368- | DDB_G0270368 | wild type |
DBS0236036 | DDB_G0270744- | DDB_G0270744 | wild type |
DBS0351081 | DDB_G0272538- | DDB_G0272538 | delayed aggregation | increased cell-substrate adhesion |
LAS29 | DDB_G0273201- | DDB_G0273201 | decreased socially cooperative development |
LAS8 | DDB_G0273809- | zplC-1 | zplC-2 | decreased socially cooperative development |
LAS43 | DDB_G0274429- | DDB_G0274429 | decreased socially cooperative development |
DBS0351079 | DDB_G0274679- | DDB_G0274679 | delayed aggregation | increased cell-substrate adhesion | decreased cell motility |
DBS0236043 | DDB_G0276221- | fam21 | wild type |
DBS0236042 | DDB_G0276689- | DDB_G0276689 | wild type |
DBS0236041 | DDB_G0277179- | DDB_G0277179 | wild type |
LAS26 | DDB_G0277239- | DDB_G0277239 | decreased socially cooperative development |
DBS0236045 | DDB_G0277575- | DDB_G0277575 | wild type |
DBS0236044 | DDB_G0278315- | DDB_G0278315 | wild type |
LAS34 | DDB_G0278585- | DDB_G0278585 | decreased socially cooperative development |
DBS0236038 | DDB_G0279005- | cnot11 | wild type |
DBS0236032 | DDB_G0279163- | DDB_G0279163 | wild type |
DBS0236033 | DDB_G0279163- | DDB_G0279163 | wild type |
LAS70 | DDB_G0279405- | DDB_G0279405 | decreased socially cooperative development |
DBS0236028 | DDB_G0279609- | DDB_G0279609 | wild type |
DBS0236029 | DDB_G0279609- | DDB_G0279609 | wild type |
LAS103 | DDB_G0280089- | DDB_G0280089 | decreased socially cooperative development |
LAS54 | DDB_G0280299- | DDB_G0280299 | decreased socially cooperative development |
DBS0236035 | DDB_G0280481- | DDB_G0280481 | wild type |
DBS0351082 | DDB_G0281485- | DDB_G0281485 | delayed aggregation | increased cell-substrate adhesion | decreased cell motility |
DBS0351080 | DDB_G0281497- | DDB_G0281497 | delayed aggregation | increased cell-substrate adhesion | decreased cell motility |
DBS0236019 | DDB_G0281735- | DDB_G0281735 | wild type |
DBS0236020 | DDB_G0281735- | DDB_G0281735 | wild type |
DBS0351620 | DDB_G0281735-/ DDB_G0281737- | DDB_G0281735 | DDB_G0281737 | decreased response to Gram-negative bacterium | aberrant vegetative growth |
LAS92 | DDB_G0283373- | DDB_G0283373 | decreased socially cooperative development |
LAS106 | DDB_G0283595- | DDB_G0283595 | decreased socially cooperative development |
DBS0351085 | DDB_G0284955- | DDB_G0284955 | delayed aggregation | increased cell-substrate adhesion | decreased cell motility |
LAS3 | DDB_G0287153- | DDB_G0287153 | decreased socially cooperative development |
LAS10 | DDB_G0288547- | DDB_G0288547 | decreased socially cooperative development |
LAS9 | DDB_G0289789- | DDB_G0289789 | decreased socially cooperative development |
DBS0236027 | DDB_G0290225- | DDB_G0290225 | wild type |
DBS0351086 | DDB_G0290519- | DDB_G0290519 | delayed aggregation | increased cell-substrate adhesion | decreased cell motility |
LAS7 | DDB_G0290685- | DDB_G0290685 | decreased socially cooperative development |
DG1003 | DDB_G0291992- | DDB_G0291992 | aberrant late culminant morphology |
LAS39 | DDB_G0292148- | DDB_G0292148 | decreased socially cooperative development |
DBS0236037 | DDB_G0292186- | DDB_G0292186 | wild type |
DBS0350073 | DDB_G0293074- | DDB_G0293074 | decreased spore germination | delayed aggregation |
DBS0351083 | DDB_G0293098- | DDB_G0293098 | delayed aggregation | increased cell-substrate adhesion | decreased cell motility |
DBS0236023 | DDB_G0293116- | DDB_G0293116 | wild type |
DBS0236024 | DDB_G0293116- | DDB_G0293116 | wild type |
DBS0350516 | DDB_G0293356- | DDB_G0293356 | decreased defense response to Gram-negative bacterium |
DBS0236030 | DDB_G0293762- | DDB_G0293762 | wild type |
DG1039 | DG1039- | DDB_G0284037 | aberrant fruiting body morphogenesis |
DG1040 | DG1040- | DDB_G0276029 | aberrant fruiting body morphogenesis |
DG1041 | DG1041- | DDB_G0269126 | aberrant fruiting body morphogenesis |
DG1054 | DG1054- | DDB_G0277719 | aberrant fruiting body morphogenesis |
DG1060 | DG1060- | DDB_G0281953 | aberrant fruiting body morphogenesis |
DG1062 | DG1062- | cdl1A | aberrant fruiting body morphogenesis |
DG1074 | DG1074- | DDB_G0272108 | aberrant fruiting body morphogenesis |
DG1080 | DG1080- | DDB_G0281559 | aberrant fruiting body morphogenesis |
DG1091 | DG1091- | DG1091 | decreased fruiting body size |
DG1098 | DG1098- | DG1098 | decreased fruiting body size |
DG1104 | DG1104- | DDB_G0283535 | abolished aggregation |
DG1106 | DG1106- | keaA | abolished aggregation |
DG1110 | DG1110- | DDB_G0269128 | aberrant fruiting body morphogenesis |
DG1112 | DG1112- | DG1112 | decreased stalk width |
DG1113 | DG1113- | DG1113 | increased stalk length |
DG1122 | DG1122- | DG1122 | aberrant fruiting body morphogenesis |
DG1124 | DG1124- | DG1124 | development arrests at loose mound stage |
DG2033 | DG2033- | DG2033 | development arrests at mound stage |
DG2044 | DG2044- | DG2044 | development arrests at loose mound stage |
DBS0266700 | Dd5P1- | Dd5P1 | increased chemotaxis to cAMP | decreased phagocytosis |
DBS0266705 | Dd5P1-/ Dd5P2- | Dd5P1 | Dd5P2 | increased chemotaxis to cAMP |
DBS0266704 | Dd5P1-/ Dd5P3- | Dd5P1 | Dd5P3 | increased chemotaxis to cAMP |
DBS0235660 | Dd5P2- | Dd5P2 | increased chemotaxis to cAMP | increased actin filament polymerization |
DBS0266703 | Dd5P2-/ Dd5P3- | Dd5P2 | Dd5P3 | wild type |
DBS0266702 | Dd5P3- | Dd5P3 | wild type |
DBS0266692 | Dd5P4- | Dd5P4 | increased protein localization | increased protein phosphorylation | increased contractile vacuole size | decreased defense response to Gram-negative bacterium | increased number of mound tips | aberrant contractile vacuole discharge | decreased growth rate | decreased phagocytosis | decreased engulfment during phagocytosis | aberrant endosome morphology | aberrant vacuole organization | decreased protein localization | increased cell motility | increased activation of GTPase activity |
DBS0266693 | Dd5P4-/ [act15]: Dd5P4 | Dd5P4 | wild type |
DBS0266719 | Dd5P4-/ [act15]: Dd5P4: GFP | Dd5P4 | wild type |
DBS0266695 | Dd5P4-/ [act15]: GAP5P4 | Dd5P4 | increased number of mound tips | decreased growth rate |
DBS0351414 | Dd5P4-/ [act15]: GFP: Dd5P4(D319G) | Dd5P4 | increased contractile vacuole size | aberrant contractile vacuole discharge | aberrant protein localization to contractile vacuole |
DBS0266720 | Dd5P4-/ [act15]: Hs-OCRL | Dd5P4 | decreased phagocytosis |
DBS0266721 | Dd5P4-/ [act15]: Hs-OCRL(D422A) | Dd5P4 | decreased phagocytosis |
DBS0266694 | Dd5P4-/ [act15]: cat5P4 | Dd5P4 | increased number of mound tips | decreased growth rate |
DBS0351050 | DidioMp27- | DidioMp27 | decreased defense response to Gram-negative bacterium | decreased gene expression | decreased growth rate | aberrant phototaxis |
DBS0351049 | DidioMp36- | DidioMp36 | decreased defense response to Gram-negative bacterium | decreased gene expression | decreased growth rate | aberrant phototaxis |
CW0391 | FLAG-VwkA | vwkA | increased myosin II assembly | decreased growth rate | aberrant cytokinesis | development arrests at mound stage | aberrant hypotonic response | increased protein level |
DBS0236015 | GEG04K11 (tmcB- in KAX3) | tmcB | decreased macrocyst size | aberrant macrocyst formation |
DBS0236017 | GEG10K23 (tmcC- in KAX3) | tmcC | aberrant macrocyst formation |
CW0368 | GFP-VwkA | vwkA | decreased growth rate | aberrant cytokinesis |
DBS0266872 | GFP: pcna | pcna | wild type |
DBS0350102 | GFP: pcp | pcp | aberrant contractile vacuole morphology | aberrant hypotonic response |
DBS0302615 | GFP: phgA(1-274: 283-438)/ phgA- | phgA | aberrant hypotonic response |
DBS0302614 | GFP: phgA/ phgA- | phgA | wild type |
DBS0236084 | GP138A-/ GP138B-/ GP138C-/ GP138D- | cfrA | cfrB | cfrC | cfrD | decreased gene expression |
DBS0236085 | GP138C- | cfrC | wild type |
DBS0236128 | HB3 | H3b | abolished stream development | abolished response to cAMP |
DL118 | HL216/ HL261 | gnt2 | decreased migratory slug size | decreased calcium-independent cell-cell adhesion | decreased fruiting body size |
HL220 | HL220 | gnt2 | abolished gene expression | aberrant spore coat morphology | decreased calcium-independent cell-cell adhesion |
HL241 | HL241 | alg9 | aberrant protein modification |
HL260 | HL260 | gnt2 | decreased calcium-independent cell-cell adhesion |
HMW404 | HMW404 | manA | abolished gene expression | abolished catalytic activity | abolished aggregation |
DBS0350714 | HMW437 | manA | wild type | abolished catalytic activity |
AP1 | HSPC300- | hspc300 | aberrant cytokinesis |
AP2 | HSPC300- | hspc300 | decreased actin filament polymerization | decreased cell motility | decreased vegetative cell size | decreased phototaxis | decreased pseudopodium size |
DBS0351312 | HSPC300-/ [act15]: abpB(129-295) | abpB | hspc300 | aberrant cellular process |
HTY506 | HTY506 | pkaR | aberrant spore morphology | precocious sporulation | aberrant fruiting body morphogenesis | decreased actin phosphorylation | precocious development | decreased cAMP level | decreased sporulation |
HTY507 | HTY507 | rdeA | precocious aggregation | decreased mound size | increased cAMP level | aberrant fruiting body morphogenesis |
DBS0236426 | I6KA- | I6KA | aberrant cellular homeostasis | aberrant inositol phosphate metabolic process | increased growth rate |
DBS0236444 | JH.D | cbfA | abolished gene expression | aberrant cellular metabolic process | decreased gene expression | increased gene expression | decreased growth rate | increased pinocytosis | increased vegetative cell size | decreased fruiting body size | decreased stalk width | abolished aggregation | increased phagocytosis |
DBS0236532 | M2 | manA | abolished vegetative growth |
DBS0236535 | M31 | modA | decreased catalytic activity | decreased secretion of lysosomal enzymes |
DBS0236840 | R7 | nosA | development arrests at mound stage |
DBS0266873 | RFP: pcna | pcna | wild type |
DBS0236917 | SA219 | dscA-1 | dscA-2 | dscC-1 | dscC-2 | dscD-1 | dscD-2 | dscE | abolished gene expression |
SA31 | SA31 | dscA-1 | dscA-2 | dscC-1 | dscC-2 | dscD-1 | dscD-2 | dscE | abolished gene expression | abolished stream development | aberrant microtubule cytoskeleton organization | decreased establishment of cell polarity |
DBS0264065 | V00262 | dagA | abolished stream development | abolished slug migration | abolished oscillatory cAMP signaling | abolished aggregation | abolished culmination |
DBS0264066 | V00347 | DDB_G0281917 | abolished culmination |
DBS0264073 | V10108 | DDB_G0292162 | abolished stream development | abolished slug migration | aberrant vegetative growth | abolished oscillatory cAMP signaling | abolished aggregation | abolished culmination |
DBS0264075 | V10113 | yakA | abolished stream development | abolished slug migration | aberrant vegetative growth | abolished oscillatory cAMP signaling | aberrant oscillatory cAMP signaling | abolished aggregation | abolished culmination |
DBS0264078 | V10116 | tipB | aberrant aggregation | abolished slug migration | aberrant oscillatory cAMP signaling | abolished culmination |
DBS0264079 | V10117 | DDB_G0285083 | aberrant slug migration | abolished culmination |
DBS0264081 | V10119 | DDB_G0292194 | wild type |
DBS0264083 | V10121 | zntC | wild type |
DBS0264087 | V10125 | DDB_G0293302 | aberrant slug migration | aberrant oscillatory cAMP signaling |
DBS0264088 | V10126 | tipC | aberrant culmination | aberrant slug migration | aberrant oscillatory cAMP signaling |
DBS0264089 | V10127 | DG1037 | abolished stream development | abolished slug migration | abolished oscillatory cAMP signaling | aberrant oscillatory cAMP signaling | abolished aggregation | abolished culmination |
DBS0264098 | V10136 | DDB_G0293590 | wild type | aberrant culmination | aberrant slug migration | aberrant oscillatory cAMP signaling |
DBS0264099 | V10137 | yelA | aberrant aggregation | abolished slug migration | aberrant culmination | aberrant oscillatory cAMP signaling |
DBS0264100 | V10138 | tipC | wild type |
DBS0264106 | V10144 | comH | aberrant aggregation | abolished slug migration | abolished culmination |
DBS0264108 | V10146 | yakA | abolished stream development | abolished slug migration | aberrant vegetative growth | abolished oscillatory cAMP signaling | abolished aggregation | abolished culmination |
DBS0264109 | V10147 | tipA | aberrant aggregation | abolished slug migration | aberrant culmination | aberrant stream morphology | aberrant slug migration | aberrant oscillatory cAMP signaling | abolished culmination |
DBS0264112 | V10150 | swp1 | wild type |
DBS0264116 | V10155 | DDB_G0282093 | abolished stream development | aberrant aggregation | abolished slug migration | aberrant culmination | aberrant slug migration | aberrant stream morphology | aberrant oscillatory cAMP signaling | abolished aggregation | abolished culmination |
DBS0264118 | V10157 | usp12 | aberrant culmination | aberrant slug migration | aberrant stream morphology | abolished culmination |
DBS0264125 | V10164 | comE | aberrant vegetative growth | aberrant culmination | aberrant slug migration | abolished culmination |
DBS0264126 | V10165 | comD | aberrant aggregation | abolished slug migration | aberrant culmination | aberrant oscillatory cAMP signaling |
DBS0264128 | V10167 | DG1098 | wild type | aberrant oscillatory cAMP signaling |
DBS0264129 | V10168 | prsC | wild type | aberrant slug migration |
DBS0264131 | V10170 | DDB_G0283015 | aberrant culmination | aberrant slug migration | aberrant oscillatory cAMP signaling | abolished culmination |
DBS0264135 | V10174 | DDB_G0288581 | aberrant vegetative growth | aberrant culmination | aberrant slug migration | aberrant stream morphology | aberrant oscillatory cAMP signaling |
DBS0264145 | V10185 | abcA5 | wild type | aberrant vegetative growth | aberrant culmination | aberrant oscillatory cAMP signaling |
DBS0264150 | V10190 | yelA | aberrant aggregation | abolished slug migration | aberrant culmination | aberrant oscillatory cAMP signaling |
DBS0264151 | V10191 | sfbA | aberrant culmination | aberrant slug migration | abolished culmination |
DBS0264152 | V10192 | tipD | aberrant aggregation | abolished slug migration | aberrant oscillatory cAMP signaling | abolished culmination |
DBS0264154 | V10194 | modA | aberrant culmination | aberrant slug migration |
DBS0264155 | V10195 | migA | aberrant culmination | aberrant stream morphology | aberrant slug migration | aberrant oscillatory cAMP signaling |
DBS0264157 | V10197 | yelA | abolished slug migration | aberrant culmination | aberrant slug migration |
DBS0264158 | V10198 | splA | aberrant aggregation | aberrant culmination | aberrant stream morphology | aberrant oscillatory cAMP signaling |
DBS0264159 | V10199 | DG1037 | abolished slug migration | aberrant stream morphology | aberrant oscillatory cAMP signaling | abolished aggregation | abolished culmination |
DBS0264160 | V10200 | DDB_G0289377 | aberrant culmination | aberrant slug migration | aberrant oscillatory cAMP signaling |
DBS0264161 | V10201 | rgaA | aberrant vegetative growth | aberrant culmination | aberrant slug migration | aberrant oscillatory cAMP signaling | abolished culmination |
DBS0264163 | V10203 | modA | wild type | aberrant vegetative growth | aberrant culmination |
DBS0264164 | V10204 | DG1124 | aberrant aggregation | aberrant stream morphology | aberrant oscillatory cAMP signaling |
DBS0264166 | V10206 | wimA | wild type |
DBS0264169 | V10209 | dcsA | abolished culmination |
DBS0264170 | V10210 | mkpA | abolished stream development | abolished slug migration | abolished oscillatory cAMP signaling | abolished aggregation | abolished culmination |
DBS0264171 | V10211 | migA | aberrant culmination | aberrant stream morphology | aberrant oscillatory cAMP signaling |
DBS0264172 | V10212 | tipC | aberrant aggregation | abolished slug migration | aberrant vegetative growth | aberrant culmination | aberrant oscillatory cAMP signaling |
DBS0264173 | V10213 | DG1098 | aberrant stream morphology | aberrant oscillatory cAMP signaling |
DBS0264175 | V10215 | cbfB | wild type |
DBS0264176 | V10216 | DDB_G0292884 | wild type | aberrant vegetative growth |
DBS0264180 | V10220 | potA | wild type |
DBS0264181 | V10221 | tipD | aberrant culmination | aberrant slug migration | aberrant oscillatory cAMP signaling |
DBS0264182 | V10222 | ctaA | wild type |
DBS0264183 | V10223 | erkA | aberrant stream morphology | aberrant oscillatory cAMP signaling |
DBS0264184 | V10224 | DG1091 | aberrant oscillatory cAMP signaling |
DBS0264185 | V10225 | acrA | aberrant culmination | aberrant slug migration | aberrant oscillatory cAMP signaling |
DBS0264186 | V10226 | ggtA | aberrant vegetative growth | aberrant culmination | aberrant slug migration | abolished aggregation | abolished culmination |
DBS0264187 | V10227 | piaA | abolished stream development | abolished slug migration | abolished oscillatory cAMP signaling | abolished aggregation | abolished culmination |
DBS0264188 | V10228 | comG | aberrant aggregation | abolished slug migration | aberrant vegetative growth | aberrant culmination | aberrant stream morphology | aberrant slug migration | aberrant oscillatory cAMP signaling | abolished culmination |
DBS0264189 | V10229 | dcsA | aberrant oscillatory cAMP signaling | abolished culmination |
DBS0264190 | V10230 | ctrA | aberrant aggregation | aberrant culmination | aberrant slug migration |
DBS0264193 | V10233 | piaA | abolished stream development | abolished slug migration | abolished oscillatory cAMP signaling | abolished aggregation | abolished culmination |
DBS0264195 | V10235 | DDB_G0285985 | wild type |
DBS0264196 | V10236 | DDB_G0270872_ps | aberrant stream morphology |
DBS0264197 | V10237 | DDB_G0278621 | wild type |
DBS0264198 | V10238 | DDB_G0269128 | aberrant culmination | aberrant slug migration |
DBS0264199 | V10239 | kif12 | wild type | aberrant culmination |
DBS0264201 | V10241 | lvsB | aberrant culmination |
DBS0264202 | V10242 | tagB | aberrant aggregation | abolished slug migration | abolished culmination |
DBS0264204 | V10244 | gbfA | aberrant culmination | aberrant slug migration |
DBS0264205 | V10245 | gefA | abolished stream development | abolished slug migration | abolished oscillatory cAMP signaling | abolished aggregation | abolished culmination |
DBS0264206 | V10246 | dicB | aberrant stream morphology | aberrant oscillatory cAMP signaling |
DBS0264207 | V10247 | yelA | aberrant aggregation | abolished slug migration | aberrant culmination | aberrant oscillatory cAMP signaling | abolished culmination |
DBS0264212 | V10252 | tagB | aberrant aggregation | abolished slug migration | abolished culmination |
DBS0264216 | V10256 | DDB_G0293302 | abolished slug migration | aberrant culmination | aberrant stream morphology | aberrant oscillatory cAMP signaling |
DBS0264218 | V10258 | rdeA | aberrant aggregation | abolished slug migration | aberrant culmination | aberrant stream morphology | aberrant oscillatory cAMP signaling | abolished culmination |
DBS0264220 | V10260 | gacT | aberrant culmination | aberrant slug migration | aberrant oscillatory cAMP signaling |
DBS0264224 | V10264 | DDB_G0282787_RTE | aberrant aggregation | wild type | abolished slug migration | aberrant stream morphology | aberrant oscillatory cAMP signaling | abolished culmination |
DBS0264225 | V10265 | lvsD | aberrant vegetative growth | aberrant culmination | aberrant oscillatory cAMP signaling |
DBS0264227 | V10267 | DDB_G0292260_RTE | aberrant aggregation | aberrant stream morphology |
DBS0264228 | V10268 | dhkA | aberrant culmination | aberrant slug migration | aberrant stream morphology | aberrant oscillatory cAMP signaling |
DBS0264229 | V10269 | helC | wild type | aberrant culmination | aberrant slug migration | abolished culmination |
DBS0264230 | V10270 | mekA | aberrant vegetative growth | aberrant culmination | aberrant stream morphology | aberrant oscillatory cAMP signaling |
DBS0264231 | V10271 | lvsB | abolished stream development | abolished slug migration | aberrant oscillatory cAMP signaling | abolished aggregation | abolished culmination |
DBS0264232 | V10272 | modA | abolished stream development | abolished slug migration | aberrant oscillatory cAMP signaling | abolished aggregation | abolished culmination |
DBS0264233 | V10273 | DDB_G0283535 | wild type | aberrant vegetative growth |
DBS0264234 | V10274 | DG1113 | aberrant vegetative growth | aberrant culmination | aberrant oscillatory cAMP signaling |
DBS0264235 | V10275 | DG1122 | abolished stream development | wild type | abolished slug migration | aberrant vegetative growth | aberrant stream morphology | aberrant oscillatory cAMP signaling | abolished aggregation | abolished culmination |
DBS0264236 | V10276 | DDB_G0270654 | wild type |
DBS0264237 | V10277 | lvsE | aberrant oscillatory cAMP signaling |
DBS0264238 | V10278 | modA | aberrant aggregation | abolished slug migration | aberrant culmination | aberrant stream morphology | aberrant slug migration | aberrant oscillatory cAMP signaling | abolished culmination |
DBS0264240 | V10280 | mekA | aberrant culmination | aberrant stream morphology | aberrant slug migration | aberrant oscillatory cAMP signaling | abolished culmination |
DBS0264241 | V10281 | DDB_G0268266 | aberrant slug migration | aberrant oscillatory cAMP signaling |
DBS0264242 | V10282 | phdA | abolished slug migration | aberrant culmination | aberrant stream morphology |
DBS0264245 | V10285 | scaA | abolished stream development | abolished slug migration | aberrant vegetative growth | aberrant oscillatory cAMP signaling | abolished aggregation | abolished culmination |
DBS0264246 | V10286 | amdA | wild type | aberrant culmination |
DBS0264247 | V10287 | helC | wild type | aberrant culmination | aberrant slug migration |
DBS0264251 | V10300 | DDB_G0278333 | aberrant culmination | aberrant slug migration | aberrant oscillatory cAMP signaling |
DBS0264269 | V10322 | roco5 | aberrant culmination | aberrant slug migration | aberrant oscillatory cAMP signaling | abolished culmination |
DBS0264272 | V10326 | DG1113 | wild type | aberrant oscillatory cAMP signaling |
DBS0264275 | V10330 | DDB_G0282121 | wild type |
DBS0264278 | V10342 | DDB_G0279727 | wild type |
DBS0264281 | V10356 | DDB_G0275747 | aberrant slug migration |
DBS0264283 | V10363 | msh5 | wild type |
DBS0264284 | V10367 | DDB_G0282463 | aberrant vegetative growth | aberrant culmination | aberrant slug migration | aberrant oscillatory cAMP signaling | abolished culmination |
DBS0264287 | V10431 | kcnma1 | wild type | aberrant culmination | aberrant slug migration |
DBS0264288 | V10432 | DDB_G0291103 | wild type |
DBS0264290 | V10435 | gefL | abolished slug migration | aberrant culmination | aberrant slug migration | aberrant oscillatory cAMP signaling |
DBS0264292 | V10438 | DDB_G0275671 | wild type |
DBS0264295 | V10442 | pks3 | wild type |
DBS0264297 | V10445 | DDB_G0290835 | aberrant slug migration |
DBS0264303 | V10460 | abcC9 | aberrant slug migration |
DBS0264316 | V10483 | yod1 | aberrant aggregation | aberrant culmination | aberrant slug migration | aberrant oscillatory cAMP signaling | abolished culmination |
DBS0264318 | V10490 | gefV | aberrant culmination | aberrant oscillatory cAMP signaling |
DBS0264319 | V10492 | med23 | aberrant culmination | aberrant oscillatory cAMP signaling |
DBS0264320 | V10495 | DDB_G0269128 | wild type | aberrant culmination | aberrant slug migration |
DBS0264324 | V10514 | adprt3 | aberrant stream morphology | aberrant oscillatory cAMP signaling |
DBS0264326 | V10519 | DDB_G0290575 | wild type |
DBS0264330 | V10529 | cyp508B1 | aberrant aggregation | abolished slug migration | aberrant culmination | aberrant stream morphology | aberrant slug migration | aberrant oscillatory cAMP signaling |
DBS0264331 | V10530 | DDB_G0270344 | wild type | aberrant slug migration | aberrant oscillatory cAMP signaling |
DBS0264334 | V10534 | DDB_G0291812 | wild type | aberrant culmination |
DBS0264335 | V10535 | DDB_G0277165 | aberrant stream morphology | aberrant oscillatory cAMP signaling |
DBS0264337 | V10537 | gbpC | abolished stream development | wild type | aberrant stream morphology | aberrant oscillatory cAMP signaling |
DBS0264347 | V10567 | dagA | abolished stream development | abolished slug migration | abolished oscillatory cAMP signaling | abolished aggregation | abolished culmination |
DBS0264349 | V10570 | DDB_G0281115 | wild type | aberrant culmination | aberrant stream morphology | aberrant slug migration | aberrant oscillatory cAMP signaling |
DBS0264356 | V10588 | dhkC | wild type | aberrant stream morphology | aberrant oscillatory cAMP signaling |
DBS0264373 | V10633 | gtaG | abolished slug migration | aberrant culmination | aberrant slug migration | abolished culmination |
DBS0264377 | V10642 | fscD | wild type |
DBS0264384 | V10670 | taf2 | wild type |
DBS0264390 | V10682 | clcD | abolished stream development | abolished slug migration | abolished oscillatory cAMP signaling | aberrant oscillatory cAMP signaling | abolished aggregation | abolished culmination |
DBS0264425 | V11033 | nfaA | aberrant aggregation | wild type | aberrant stream morphology | aberrant oscillatory cAMP signaling |
DBS0264432 | V11040 | DDB_G0274177 | abolished stream development | abolished slug migration | abolished oscillatory cAMP signaling | abolished aggregation | abolished culmination |
DBS0264438 | V11047 | DDB_G0269296 | wild type |
DBS0264439 | V11048 | xrcc4 | wild type |
DBS0264444 | V11053 | dscA-1 | dscA-2 | wild type | aberrant vegetative growth |
DBS0264446 | V11055 | ku80 | aberrant vegetative growth | aberrant culmination |
DBS0264464 | V11075 | cinC | wild type | aberrant culmination |
DBS0264480 | V11092 | cnrO | wild type |
DBS0264489 | V11105 | DDB_G0270350_ps | wild type | aberrant stream morphology | aberrant oscillatory cAMP signaling |
DBS0264512 | V11128 | DDB_G0278945 | aberrant vegetative growth | aberrant stream morphology | aberrant oscillatory cAMP signaling |
DBS0264575 | V30069 | DDB_G0284619 | aberrant stream morphology | aberrant oscillatory cAMP signaling |
DBS0264607 | V30110 | alg9 | wild type | aberrant vegetative growth | aberrant oscillatory cAMP signaling |
DBS0264630 | V30133 | DDB_G0272953 | wild type | aberrant stream morphology | aberrant oscillatory cAMP signaling |
DBS0264634 | V30137 | DDB_G0289529 | wild type |
DBS0264662 | V30165 | alg9 | wild type | aberrant culmination | aberrant stream morphology | aberrant oscillatory cAMP signaling |
DBS0264668 | V30171 | DDB_G0285261 | wild type | aberrant vegetative growth | aberrant stream morphology | aberrant oscillatory cAMP signaling |
DBS0264677 | V30180 | gpaF | wild type | aberrant stream morphology | aberrant oscillatory cAMP signaling |
DBS0264684 | V30188 | DDB_G0287723 | wild type | aberrant stream morphology | aberrant oscillatory cAMP signaling |
DBS0264687 | V30191 | DDB_G0288219 | wild type | aberrant vegetative growth |
DBS0264700 | V30213 | act9 | wild type | aberrant culmination |
DBS0264715 | V30229 | dhx35 | wild type | aberrant oscillatory cAMP signaling |
DBS0264716 | V30230 | regA | aberrant aggregation | abolished slug migration | aberrant stream morphology | aberrant oscillatory cAMP signaling | abolished culmination |
DBS0264731 | V30245 | DDB_G0279461 | wild type | aberrant culmination |
DBS0264749 | V30264 | DDB_G0273651 | wild type |
DBS0264752 | V30267 | DDB_G0283759 | wild type |
DBS0264756 | V30271 | ncapGa | wild type |
DBS0264763 | V30278 | tnlA | wild type |
DBS0264765 | V30280 | ppt1 | wild type |
DBS0264768 | V30283 | DDB_G0270872_ps | wild type |
DBS0264770 | V30285 | DDB_G0293762 | wild type | aberrant vegetative growth |
DBS0264773 | V30288 | DDB_G0293300 | wild type | aberrant stream morphology | aberrant oscillatory cAMP signaling |
DBS0264777 | V30292 | glpD | wild type |
DBS0264781 | V30296 | DDB_G0270212 | wild type |
DBS0264785 | V30303 | pakE | aberrant oscillatory cAMP signaling |
DBS0264823 | V30341 | frmB | wild type | aberrant culmination | aberrant stream morphology |
DBS0264832 | V30350 | DDB_G0284059 | wild type |
DBS0264835 | V30353 | DDB_G0282471 | wild type |
DBS0264853 | V30371 | abpC | aberrant aggregation | abolished slug migration | aberrant culmination | abolished culmination |
DBS0264905 | V30427 | DDB_G0291926 | aberrant culmination | aberrant slug migration | aberrant stream morphology | aberrant oscillatory cAMP signaling |
DBS0264910 | V30432 | malA | wild type |
DBS0264922 | V30446 | DDB_G0269430 | wild type |
DBS0264924 | V30448 | DDB_G0269680 | wild type | aberrant oscillatory cAMP signaling |
DBS0264941 | V30466 | dtfA | wild type | aberrant oscillatory cAMP signaling |
DBS0264992 | V30522 | DDB_G0288007 | wild type | aberrant stream morphology | aberrant oscillatory cAMP signaling |
DBS0264994 | V30524 | prmt5 | aberrant culmination | aberrant stream morphology | aberrant slug migration | aberrant oscillatory cAMP signaling | abolished culmination |
DBS0265002 | V30532 | lvsA | wild type | abolished slug migration | aberrant oscillatory cAMP signaling | abolished aggregation | abolished culmination |
DBS0265017 | V30547 | DDB_G0279105 | wild type | aberrant vegetative growth | aberrant culmination | aberrant stream morphology | aberrant oscillatory cAMP signaling |
DBS0265029 | V30561 | DDB_G0277355 | wild type | aberrant culmination |
DBS0265045 | V30578 | DDB_G0277165 | aberrant culmination | aberrant slug migration | aberrant oscillatory cAMP signaling |
DBS0265049 | V30582 | DDB_G0291722 | wild type |
DBS0265064 | V30604 | DDB_G0279461 | abolished slug migration | aberrant culmination | aberrant slug migration | aberrant stream morphology | aberrant oscillatory cAMP signaling |
DBS0265066 | V30606 | adkB | wild type |
DBS0265099 | V30642 | tipC | aberrant aggregation | abolished slug migration | aberrant oscillatory cAMP signaling | abolished culmination |
DBS0265126 | V30673 | dicB | aberrant aggregation | abolished slug migration | aberrant culmination | aberrant oscillatory cAMP signaling |
DBS0265140 | V30688 | DDB_G0279727 | wild type | aberrant culmination |
DBS0265170 | V30724 | cnrK | wild type |
DBS0265206 | V30766 | rhgA | wild type |
DBS0265226 | V30789 | itpa | wild type |
DBS0265231 | V30794 | tpsA | wild type |
DBS0265247 | V30814 | adprt1B | wild type |
DBS0265279 | V30846 | DDB_G0286091 | wild type |
DBS0265286 | V30853 | DDB_G0292058 | wild type |
DBS0265296 | V30863 | DDB_G0269128 | wild type |
DBS0265302 | V30869 | DDB_G0292454 | wild type | aberrant vegetative growth |
DBS0265303 | V30870 | gxcJJ | wild type | aberrant oscillatory cAMP signaling |
DBS0265309 | V30876 | DDB_G0268248 | wild type | aberrant stream morphology | aberrant oscillatory cAMP signaling |
DBS0265311 | V30879 | exoc2 | wild type | aberrant stream morphology | aberrant oscillatory cAMP signaling |
DBS0265319 | V30887 | adcC | wild type |
DBS0265339 | V30912 | DDB_G0283821 | wild type | aberrant oscillatory cAMP signaling |
DBS0265348 | V30921 | snpC | wild type | aberrant culmination |
DBS0265422 | V30995 | DDB_G0282959 | wild type |
DBS0265466 | V31043 | DDB_G0275917 | aberrant aggregation | wild type | aberrant vegetative growth | aberrant slug migration | abolished culmination |
DBS0265497 | V31075 | DDB_G0282985 | wild type | abolished slug migration | aberrant culmination | aberrant stream morphology | aberrant oscillatory cAMP signaling | abolished aggregation |
DBS0265520 | V31102 | DDB_G0287865 | wild type |
DBS0265529 | V31111 | vps13E | wild type | aberrant culmination | aberrant stream morphology | aberrant oscillatory cAMP signaling |
DBS0265539 | V31121 | DDB_G0270912 | wild type | aberrant vegetative growth | aberrant oscillatory cAMP signaling |
DBS0265567 | V31151 | DDB_G0275539 | wild type | aberrant vegetative growth | abolished culmination |
DBS0265573 | V31157 | act9 | wild type |
DBS0265588 | V31173 | ggtA | aberrant vegetative growth | aberrant culmination | aberrant stream morphology | aberrant oscillatory cAMP signaling |
DBS0265662 | V31255 | psiN | wild type | aberrant culmination | aberrant stream morphology | aberrant oscillatory cAMP signaling |
DBS0265688 | V31281 | DDB_G0286417 | wild type | aberrant culmination | aberrant stream morphology | aberrant oscillatory cAMP signaling |
DBS0265701 | V31294 | DDB_G0268424 | wild type |
DBS0265873 | V31480 | DDB_G0284177 | aberrant culmination |
DBS0265890 | V31501 | DDB_G0282985 | wild type | aberrant culmination | aberrant oscillatory cAMP signaling |
DBS0265908 | V31523 | tmem184C | wild type | aberrant culmination |
DBS0265911 | V31528 | DDB_G0279945 | aberrant culmination |
DBS0265938 | V31568 | rsc12 | aberrant culmination |
DBS0265947 | V31583 | DDB_G0282943 | wild type |
DBS0265992 | V31640 | DDB_G0274343 | wild type |
DBS0266000 | V31649 | DDB_G0290383 | wild type | aberrant culmination |
DBS0266021 | V31670 | DDB_G0281269 | wild type |
DBS0266022 | V31671 | dhkA | aberrant culmination | aberrant slug migration |
DBS0266036 | V31685 | tipC | aberrant aggregation | wild type | abolished slug migration | aberrant culmination | aberrant stream morphology | aberrant oscillatory cAMP signaling |
DBS0266084 | V31738 | dcsA | wild type | aberrant culmination | abolished culmination |
DBS0266088 | V31742 | dstA | aberrant culmination | aberrant slug migration | abolished culmination |
DBS0266089 | V31743 | DDB_G0273459 | aberrant aggregation | aberrant culmination | aberrant stream morphology | aberrant slug migration | aberrant oscillatory cAMP signaling |
DBS0266098 | V31752 | oplah | wild type | aberrant oscillatory cAMP signaling |
DBS0266149 | V31807 | gpt1 | wild type | aberrant vegetative growth | abolished vegetative growth |
DBS0266153 | V31811 | gpt1 | wild type | aberrant vegetative growth | aberrant culmination | aberrant oscillatory cAMP signaling |
DBS0266190 | V31853 | chlA | aberrant aggregation | aberrant culmination | aberrant slug migration | aberrant oscillatory cAMP signaling |
DBS0266195 | V31858 | DDB_G0286341 | wild type | aberrant stream morphology | aberrant oscillatory cAMP signaling |
DBS0266246 | V31916 | psiF | wild type | aberrant vegetative growth | aberrant culmination | aberrant oscillatory cAMP signaling |
DBS0266249 | V31919 | DDB_G0276251 | aberrant culmination | aberrant stream morphology | aberrant slug migration | aberrant oscillatory cAMP signaling |
DBS0266253 | V31923 | DDB_G0268314 | wild type | aberrant culmination |
DBS0266258 | V31928 | DDB_G0268314 | wild type |
DBS0266271 | V31941 | manA | aberrant aggregation | aberrant culmination | aberrant stream morphology | aberrant slug migration | aberrant oscillatory cAMP signaling |
DBS0266299 | V31970 | DDB_G0280581 | wild type | aberrant stream morphology | aberrant oscillatory cAMP signaling |
DBS0266309 | V31982 | DDB_G0286341 | abolished stream development | wild type | aberrant stream morphology | aberrant oscillatory cAMP signaling |
DBS0266316 | V31989 | DDB_G0270342 | abolished stream development | wild type | abolished slug migration | aberrant culmination | aberrant oscillatory cAMP signaling |
DBS0237041 | VatMpr | vatM | increased protein localization to cytoplasm | decreased phagocytosis | decreased growth rate | aberrant regulation of intracellular pH |
DBS0237044 | VatMpr/ [act15]: vatM | vatM | wild type |
DBS0237042 | VatMpr/ [act15]: vatM: GFP | vatM | decreased growth rate |
DBS0237236 | [AS]: [tet]: trrA | trrA | decreased growth rate | delayed development | abolished aggregation |
DBS0350570 | [AS]PARP | DDB_G0286613 | DDB_G0289141 | adprt1A | adprt1B | adprt2 | adprt3 | adprt4 | pARTf | pARTg | decreased cell death | aberrant positive regulation of mitochondrial membrane potential |
DBS0350559 | [AS]act15: adprt1A | adprt1A | development arrests at loose mound stage | decreased gene expression | decreased ATP level | increased mitochondrial fission |
DBS0351092 | [AS]aif | aif | aberrant cellular homeostasis | aberrant regulation of mitochondrial membrane potential | aberrant mitochondrion morphology | decreased ATP level | increased gene expression | decreased gene expression | decreased growth rate | aberrant cell cycle | increased necrotic cell death | delayed development | aberrant response to oxidative stress | aberrant cell morphology | increased mitochondrial fission | aberrant mitochondrion organization |
DBS0304456 | [AS]alrA/ gcsA- | alrA | gcsA | aberrant cellular metabolic process | increased gene expression | decreased growth rate | mitotic G1 phase arrest |
DBS0237273 | [AS]calA | calA | abolished cytokinesis |
DBS0350897 | [AS]carA | carA-1 | carA-2 | abolished aggregation |
DBS0237222 | [AS]cf60 | cf60 | increased mound size | decreased number of mounds |
DBS0237228 | [AS]cfrA/ [AS]cfrB | cfrA | cfrB | decreased sexual fusion |
DBS0237223 | [AS]chcA | chcA | decreased pinocytosis | delayed hypotonic response | decreased number of vacuoles | decreased vegetative cell size | aberrant vacuole organization | abolished aggregation |
DBS0237224 | [AS]cmfA | cmfA | abolished aggregation |
DBS0236982 | [AS]csbA/ csbB | csbA | csbB | decreased cell-cell adhesion |
DBS0237225 | [AS]cupB | cupB | abolished aggregation |
DBS0350979 | [AS]deeJ | deeJ | decreased pinocytosis | decreased phagocytosis | aberrant fruiting body morphogenesis |
DBS0237226 | [AS]dia1 | dia1 | decreased gene expression | precocious aggregation |
DBS0351176 | [AS]dscA | dscA-1 | dscA-2 | abolished stream development |
DBS0238235 | [AS]dutA | dutA | wild type |
DBS0350560 | [AS]ecmB: adprt1A | adprt1A | development arrests at slug stage |
DBS0350676 | [AS]erkA | erkA | aberrant vegetative growth |
DBS0237229 | [AS]gpaA | gpaA | wild type |
DBS0351057 | [AS]gshB | gshB | increased slug migration |
HPF414 | [AS]hspA | hspA | decreased growth rate | aberrant fruiting body morphogenesis | decreased defense response to bacterium |
DBS0351041 | [AS]hspA/ [AS]ndkC-1 | hspA | ndkC-1 | ndkC-2 | wild type |
DBS0238749 | [AS]hspA/ snfA | hspA | snfA | wild type |
DBS0252819 | [AS]hssA | hssA | wild type |
DBS0351171 | [AS]htrA | htrA | decreased growth rate | aberrant fruiting body morphogenesis |
DBS0237230 | [AS]ino1 | ino1 | abolished vegetative growth |
DBS0304425 | [AS]mppA1 | mppA1 | delayed development |
DBS0304424 | [AS]mppB | mppB | increased gene expression |
DBS0236725 | [AS]patA | patA | decreased growth rate |
DBS0237504 | [AS]pikE | pikE | aberrant stalk morphogenesis | decreased growth rate |
DBS0237231 | [AS]ppiA | ppiA | increased stalk length |
DBS0237232 | [AS]proA | proA | wild type |
DBS0350355 | [AS]proA-/ proB-/ lmpA- | lmpA | proA | proB | abolished sporulation | wild type |
DBS0351311 | [AS]proA/ abpB(129-295) | abpB | proA | aberrant cellular process |
DBS0236827 | [AS]proA/ proB- | proA | proB | decreased exocytosis | decreased pinocytosis | aberrant exocytosis | increased actin filament polymerization | development arrests at slug stage | aberrant cytokinesis | decreased cell motility | abolished vegetative growth | decreased secretion of lysosomal enzymes | increased phagocytosis |
DBS0238036 | [AS]proA/ proB-/ [act15]: proA | proA | proB | wild type |
DBS0238037 | [AS]proA/ proB-/ [act15]: proB | proA | proB | wild type |
DBS0238035 | [AS]proA/ proB-/ [unk]: FLAG: proC | proA | proB | proC | wild type |
DBS0350334 | [AS]proA/ proB-/ scrA- | proA | proB | scrA | decreased exocytosis | decreased pinocytosis | decreased secretion of lysosomal enzymes |
DBS0350117 | [AS]ptcB | ptcB | decreased growth rate |
DBS0236851 | [AS]rapA | rapA | decreased pinocytosis | aberrant osmosensory signaling pathway | decreased phagocytosis | abolished vegetative growth | increased actin phosphorylation | aberrant hyperosmotic response |
DBS0351303 | [AS]rheb | rheb | decreased growth rate | increased macropinocytosis | increased phagocytosis |
DBS0350574 | [AS]rps4 | rps4 | decreased spore germination | aberrant actin cytoskeleton organization | aberrant vegetative growth | decreased mound size | decreased spore size | aberrant fruiting body morphogenesis | decreased sporulation |
DBS0236904 | [AS]rps4 | mrps4 | delayed aggregation | aberrant fruiting body morphogenesis |
DBS0237234 | [AS]smlA | smlA | decreased fruiting body size |
DBS0238748 | [AS]snfA | snfA | decreased number of mitochondria | decreased ATP level | increased growth rate | decreased fruiting body size | aberrant mitochondrion organization |
DBS0304498 | [AS]sslA1 | sslA1 | decreased fruiting body size |
DBS0237235 | [AS]tcp1 | tcp1 | decreased growth rate | development arrests at mound stage | aberrant fruiting body morphogenesis |
DBS0351302 | [AS]tpp1 | tpp1 | aberrant cellular process | decreased growth rate | aberrant sorocarp development | increased macropinocytosis | increased phagocytosis |
DBS0351218 | [AS]twm1 | twm1 | decreased growth rate |
DBS0350649 | [AS]vatB | vatB | delayed aggregation | aberrant slug migration | aberrant response to chemical |
DBS0306101 | [AS]vatP | vatP | decreased calcium ion import | decreased growth rate |
DBS0306102 | [AS]vatP | vatP | decreased calcium ion import | decreased growth rate | delayed development |
DBS0237276 | [OE]: GFP: gxcA | gxcA | abolished aggregation |
DBS0237279 | [OE]: HA: rab21(Q66L) | rab21 | increased phagocytosis | aberrant cytoskeleton organization |
DBS0237280 | [OE]: HA: rab21(T21N) | rab21 | decreased phagocytosis | aberrant actin filament organization |
DBS0237274 | [OE]: chlim | ChLim | increased actin filament polymerization | decreased phagocytosis | decreased growth rate |
DBS0350519 | [OE]: egeA | egeA | decreased protein level | abolished aggregation |
DBS0237275 | [OE]: gbfA | gbfA | precocious prespore gene expression |
JH182 | [OE]: gpaD | gpaD | aberrant fruiting body morphogenesis | decreased sporulation |
JH258 | [OE]: gpaE | gpaE | precocious prestalk gene expression | precocious prespore gene expression | precocious development of tipped mound |
DBS0348921 | [OE]: ipkA1 | ipkA1 | aberrant inositol phosphate metabolic process | decreased response to lithium | aberrant gene expression |
DBS0348922 | [OE]: itpk1 | itpk1 | aberrant inositol phosphate metabolic process | decreased response to lithium | aberrant gene expression |
DBS0237281 | [OE]: limF | limF | increased actin filament polymerization | increased phagocytosis |
DBS0237282 | [OE]: pakC | pakC | decreased cell motility |
DBS0236962 | [OE]: pdiA | pdiA | delayed aggregation |
DBS0237015 | [OE]: pdiA | pdiA | aberrant development of tipped mound | abolished culmination | abolished slug development |
DBS0237283 | [OE]: rasB(G12T) | rasB | aberrant cytokinesis |
DBS0302685 | [OE]: sgcA(1-2000)(N1106A): GFP/ gca-/ sgcA- | gcA | sgcA | decreased chemotaxis rate |
DBS0302683 | [OE]: sgcA(878-2843)(N1106A): GFP/ gca-/ sgcA- | gcA | sgcA | decreased chemotaxis rate |
DBS0302681 | [OE]: sgcA(878-2843): GFP/ sgcA- | gcA | sgcA | aberrant chemotaxis to cAMP | decreased chemotaxis rate |
DBS0302682 | [OE]: sgcA(N1106A): GFP/ gca-/ sgcA- | gcA | sgcA | increased lateral pseudopodium formation | aberrant chemotaxis to cAMP | aberrant stream morphology | decreased chemotaxis rate |
DBS0302684 | [OE]: sgcA: GFP/ gca-/ sgcA- | gcA | sgcA | increased lateral pseudopodium formation | decreased chemotaxis rate |
DBS0237284 | [OE]GFP: gxcA(1-750: 764-1217) | gxcA | development arrests at loose mound stage |
DBS0237285 | [OE]GFP: gxcA(1-750: 764-984) | gxcA | development arrests at loose mound stage |
DBS0266621 | [OE]mipp1 | mipp1 | aberrant inositol phosphate metabolic process | aberrant gene expression | increased response to lithium |
DBS0237299 | [RNAi]DDB_G0270366 | DDB_G0270366 | wild type |
DBS0237300 | [RNAi]DDB_G0270368 | DDB_G0270368 | wild type |
DBS0237301 | [RNAi]DDB_G0271700 | DDB_G0271700 | wild type |
DBS0237304 | [RNAi]DDB_G0273449 | DDB_G0273449 | DDB_G0273577 | wild type |
DBS0237303 | [RNAi]DDB_G0279609 | DDB_G0279609 | wild type |
DBS0237306 | [RNAi]DDB_G0290063 | DDB_G0290063 | wild type |
DBS0237302 | [RNAi]DDB_G0290225 | DDB_G0290225 | wild type |
DBS0237298 | [RNAi]DDB_G0293116 | DDB_G0293116 | wild type |
DBS0237305 | [RNAi]DDB_G0293762 | DDB_G0293762 | wild type |
DBS0237294 | [RNAi]DidioMp05 | DidioMp05 | wild type |
DBS0350172 | [RNAi]allC | allC | development arrests at loose mound stage | decreased protein level | decreased gene expression | decreased vegetative cell size | increased growth rate |
DBS0350070 | [RNAi]canA | canA | aberrant sorus morphology | aberrant response to cation stress | increased defense response to Gram-negative bacterium | decreased fruiting body size | decreased stalk length |
DBS0350727 | [RNAi]cepE | cepE | increased number of centrosomes | aberrant cell separation during cytokinesis | aberrant mitotic sister chromatid segregation |
DBS0235409 | [RNAi]cnbA | cnbA | aberrant sorus morphology | decreased gene expression | aberrant response to cation stress | increased defense response to Gram-negative bacterium | aberrant stalk cell differentiation | decreased stalk length |
DBS0349787 | [RNAi]ctnnA | ctnnA | abolished epithelium-like organization | abolished stalk development | aberrant protein secretion | abolished establishment of cell polarity | aberrant Golgi localization | aberrant centrosome localization | abolished culmination | aberrant protein localization |
DBS0349923 | [RNAi]ctnnA/ [act15]: GFP-mhcA | ctnnA | aberrant stalk morphogenesis | decreased epithelium-like organization | aberrant protein localization |
DBS0237537 | [RNAi]enlA | enlA | decreased substrate adhesion-dependent cell spreading | decreased cell-substrate adhesion | aberrant cytokinesis |
DBS0237295 | [RNAi]fimA | fimA | wild type |
DBS0349944 | [RNAi]fttB | fttB | increased number of mound tips | aberrant cytokinesis | decreased growth rate | delayed development | decreased chemotaxis to cAMP | aberrant cytoskeleton organization |
DBS0237308 | [RNAi]gmsA | gmsA | decreased sexual fusion |
DBS0237309 | [RNAi]gsr | gsr | precocious culmination | decreased cell migration to prestalk region | precocious gene expression |
DBS0252820 | [RNAi]hssA | hssA | wild type |
DBS0237307 | [RNAi]kctd9 | kctd9 | wild type |
DBS0350940 | [RNAi]kif6 | kif6 | aberrant mitotic spindle organization |
DBS0237310 | [RNAi]lipA | lipA | wild type |
DBS0349871 | [RNAi]lkb1 | lkb1 | abolished prespore cell differentiation | delayed aggregation | aberrant slug development | aberrant sorocarp development | aberrant response to osmotic stress | aberrant response to oxidative stress | aberrant regulation of protein kinase activity | increased prestalk cell differentiation | decreased sporulation |
DBS0350643 | [RNAi]nse1 | nse1 | aberrant response to UV | aberrant stream morphology | decreased fruiting body size |
DBS0350644 | [RNAi]nse4 | nse4 | decreased gene expression | aberrant response to UV | aberrant stream morphology | decreased fruiting body size |
DBS0237296 | [RNAi]pks16 | pks16 | wild type |
DBS0237297 | [RNAi]psiM | psiM | wild type |
DBS0237311 | [RNAi]racF2 | racF2 | abolished vegetative growth |
DBS0237312 | [RNAi]rasZ | rasZ | wild type |
DBS0350488 | [RNAi]rmd1 | rmd1 | aberrant cell separation during cytokinesis |
DBS0238734 | [RNAi]sdhA | sdhA | abolished aggregation | decreased phototaxis |
DBS0351295 | [RNAi]sir2D | sir2D | decreased gene expression | delayed development |
DBS0351599 | [RNAi]srtA | srtA | increased pre-miRNA processing |
DBS0304564 | [RNAi]sun1 | sun1 | aberrant nucleus morphology | increased vegetative cell size |
DBS0349929 | [RNAi]tacA | tacA | aberrant response to cation stress | increased gene expression | delayed development | aberrant fruiting body morphogenesis |
DBS0350046 | [RNAi]tacc | tacc | aberrant response to abiotic stimulus | decreased protein level | decreased size of astral microtubules |
YLD53 | [RNAi]thg1 | thg1 | decreased growth rate |
DBS0350794 | [RNAi]tlp3 | tlp3 | decreased growth rate |
DBS0350795 | [RNAi]tlp4 | tlp4 | decreased growth rate |
DBS0237313 | [RNAi]tmcB | tmcB | aberrant macrocyst formation |
DBS0237314 | [RNAi]tmcC | tmcC | aberrant macrocyst formation |
DBS0237315 | [RNAi]trap1 | trap1 | decreased gene expression | delayed development |
DBS0237818 | [RNAi]wipA | wipA | decreased actin filament polymerization at leading edge | delayed pseudopodium formation | decreased chemotaxis to cAMP | decreased filopodium formation |
DBS0350924 | [TRE-Pmin]: 6xHis: GFP: dhcA(1384-4725(K1975T)) | dhcA | aberrant molecular function |
DBS0350052 | [TRE-Pmin]: arfA(Q71L): GFP | arfA | aberrant filopodium formation | aberrant cytokinesis |
DBS0350053 | [TRE-Pmin]: arfA(T31N): GFP | arfA | wild type | increased defense response to Gram-negative bacterium |
DBS0351202 | [act15]: 6xHis: amd1: eYFP | amd1 | decreased gene expression | increased gene expression | aberrant vegetative growth | aberrant fruiting body morphogenesis | delayed development | mitotic G1 phase arrest |
DBS0351167 | [act15]: 6xHis: ei24: eYFP | ei24 | aberrant aggregation | increased chemotaxis to cAMP | aberrant cell cycle | increased cAMP level | increased sporulation |
DBS0350674 | [act15]: 6xHis: erkA | erkA | aberrant slug development |
DBS0351253 | [act15]: 6xHis: sesn: eYFP | sesn | aberrant aggregation | decreased protein level | increased gene expression | decreased growth rate | aberrant response to oxidative stress |
DBS0349845 | [act15]: 7xHis: myoK: Ty1 | myoK | aberrant cortical actin cytoskeleton organization | aberrant engulfment during phagocytosis | aberrant cell morphology |
DBS0237100 | [act15]: CFP: racC(G15V) | racC | increased actin filament polymerization |
DBS0237101 | [act15]: CFP: racC(T20N) | racC | decreased actin filament polymerization | aberrant cytokinesis | abolished positive chemotaxis |
DBS0350908 | [act15]: DD: GFP: rab8A(N128I) | rab8A | increased contractile vacuole size | increased number of contractile vacuoles | abolished protein localization to contractile vacuole |
DBS0350909 | [act15]: DD: GFP: rab8A(Q74L) | rab8A | aberrant contractile vacuole localization | increased number of contractile vacuoles | decreased contractile vacuole size |
DBS0266512 | [act15]: DDB_G0272656 | sigN4 | wild type |
DBS0350566 | [act15]: FLAG: Rab14(Q67L) | rab14 | increased lysosome size | increased post-lysosomal vacuole size | aberrant phagosome maturation | increased endosomal vesicle fusion |
DBS0350049 | [act15]: FLAG: cycC | cycC | precocious development of tipped mound |
DBS0350321 | [act15]: FLAG: hbx4 | hbx4 | aberrant aggregation | abolished gene expression | abolished slug migration | decreased growth rate | aberrant cytokinesis |
DBS0350322 | [act15]: FLAG: hbx4/ [act15]: cadA | cadA | hbx4 | wild type |
DBS0350325 | [act15]: FLAG: hbx4/ [ecmAO]: lacZ | hbx4 | decreased spore germination | increased prestalk gene expression | abolished prespore gene expression | increased prestalk cell differentiation |
DBS0351294 | [act15]: FLAG: mybB | mybB | increased gene expression | precocious development |
DBS0238107 | [act15]: FLAG: ppp4C | ppp4c | wild type |
DBS0238108 | [act15]: FLAG: ppp4C(H113Q) | ppp4c | development arrests at mound stage | delayed development |
DBS0351488 | [act15]: FLAG: rasC(Q62L) | rasC | abolished protein localization to plasma membrane | increased actin filament polymerization | decreased chemotaxis to cAMP |
DBS0351292 | [act15]: FLAG: sir2A | sir2A | delayed development |
DBS0351293 | [act15]: FLAG: sir2C | sir2C | delayed development |
DBS0351291 | [act15]: FLAG: sir2D | sir2D | increased gene expression | precocious development |
DBS0237110 | [act15]: GFP(S65T)-racG | racG | increased filopodium formation | decreased actin filament polymerization | decreased cell motility | increased phagocytosis |
DBS0304572 | [act15]: GFP: abpD(1441-1736) | abpD | abolished protein localization to nuclear envelope |
DBS0304571 | [act15]: GFP: abpD(1441-1738) | abpD | abolished protein localization to nuclear envelope |
DBS0304573 | [act15]: GFP: abpD(1441-1738,1737P/ A) | abpD | abolished protein localization to nuclear envelope |
DBS0237114 | [act15]: GFP: abpE(413-481) | abpE-1 | abpE-2 | increased lateral pseudopodium formation |
DBS0237116 | [act15]: GFP: act15 | act15 | abolished cytokinesis | decreased cell motility | aberrant cell morphology |
DBS0351483 | [act15]: GFP: aqpB(1-208,219-294) | aqpB | decreased hypotonic response |
DBS0351097 | [act15]: GFP: cbpG | cbpG | increased cell-substrate adhesion | increased vegetative cell size | decreased chemotaxis to cAMP | abolished aggregation |
DBS0350593 | [act15]: GFP: cepL | cepL | decreased growth rate | decreased phagocytosis | increased vegetative cell size | increased cell-substrate adhesion | aberrant centrosome localization | decreased establishment of cell polarity |
DBS0350594 | [act15]: GFP: cepL(1-1114) | cepL | increased number of centrosomes | decreased growth rate | aberrant vegetative growth | increased fruiting body size | decreased phagocytosis | increased cell-substrate adhesion | decreased chemotaxis rate | aberrant phototaxis |
DBS0350595 | [act15]: GFP: cepL(1-763) | cepL | increased number of centrosomes | decreased growth rate | aberrant vegetative growth | increased fruiting body size | decreased phagocytosis | increased cell-substrate adhesion | decreased chemotaxis rate | aberrant phototaxis |
DBS0350596 | [act15]: GFP: cepL(763-1114) | cepL | development arrests at loose mound stage | abolished establishment of cell polarity | delayed aggregation | decreased vegetative cell size | increased cell-substrate adhesion | decreased chemotaxis rate | increased growth rate | aberrant phototaxis | delayed gene expression |
DBS0350460 | [act15]: GFP: docD | docD | increased actin filament polymerization | increased cell motility | increased pseudopodium formation |
DBS0350288 | [act15]: GFP: forF(1-1087) | forF | decreased pinocytosis | decreased phagocytosis | decreased growth rate |
DBS0235662 | [act15]: GFP: forH(1-425) | forH | abolished protein localization to pseudopodium |
DBS0350984 | [act15]: GFP: frmB | frmB | decreased spore size | aberrant stalk development |
DBS0304973 | [act15]: GFP: gefQ(173-651,818-1298) | gefQ | increased guanyl-nucleotide exchange factor activity |
DBS0304971 | [act15]: GFP: gefQ(683-833) | gefQ | decreased guanyl-nucleotide exchange factor activity |
DBS0304972 | [act15]: GFP: gefQ(910-1298) | gefQ | aberrant cytokinesis | aberrant phototaxis |
DBS0351254 | [act15]: GFP: gflB | gflB | decreased substrate adhesion-dependent cell spreading | decreased actin filament polymerization | increased cell motility |
DBS0350422 | [act15]: GFP: gpbB | gpbB | aberrant vegetative growth | delayed development |
DBS0350349 | [act15]: GFP: gtaC(1-467: 497-587) | gtaC | abolished protein localization to nucleus |
DBS0350351 | [act15]: GFP: gtaC(229-587) | gtaC | abolished protein localization to cytoplasm |
DBS0350359 | [act15]: GFP: gtaC(281-467: 497-587) | gtaC | aberrant protein localization to cytoplasm |
DBS0350352 | [act15]: GFP: gtaC(281-587) | gtaC | abolished protein localization to cytoplasm |
DBS0350360 | [act15]: GFP: gtaC(346-467: 497-587) | gtaC | aberrant protein localization to cytoplasm | aberrant protein localization to nucleus |
DBS0350353 | [act15]: GFP: gtaC(346-587) | gtaC | abolished protein localization to cytoplasm |
DBS0350350 | [act15]: GFP: gtaC(K469,470,494,496A/ R468,471A) | gtaC | abolished protein localization to nucleus |
DBS0236070 | [act15]: GFP: hcpA | hcpA | decreased growth rate | aberrant mitotic anaphase |
DBS0236071 | [act15]: GFP: hcpB | hcpB | decreased growth rate |
DBS0351562 | [act15]: GFP: impA1 | impa1 | decreased response to lithium |
DBS0237117 | [act15]: GFP: krsA | krsA | decreased slug migration |
DBS0237118 | [act15]: GFP: limE | limE | aberrant cytokinesis |
DBS0351530 | [act15]: GFP: lis1 | lis1 | decreased phagocytosis | decreased chemotaxis to folate |
DBS0349983 | [act15]: GFP: lmnB | lmnB | aberrant chromatin assembly |
DBS0350490 | [act15]: GFP: mhcA(T1823D/ T1833D/ T2029D)/ AX3 | mhcA | decreased growth rate | aberrant localization |
DBS0237120 | [act15]: GFP: nek2 | nek2 | aberrant nucleus morphology | increased number of microtubule organizing center |
DBS0350852 | [act15]: GFP: nkaP | nkaP | aberrant aggregation | decreased gene expression | increased gene expression | aberrant vegetative growth | increased chemotaxis rate |
DBS0237121 | [act15]: GFP: numA(1-117: 168-340) | numA | aberrant cytokinesis |
DBS0350338 | [act15]: GFP: pakA | pakA | increased phagocytosis |
DBS0350337 | [act15]: GFP: pakA(797-1197) | pakA | decreased phagocytosis | decreased cell motility |
DBS0237122 | [act15]: GFP: pats1(2087-2351) | pats1 | aberrant cytokinesis |
DBS0237123 | [act15]: GFP: phg2(1-245) | phg2 | decreased phagocytosis |
DBS0235442 | [act15]: GFP: pldB | pldB | abolished aggregation |
DBS0237702 | [act15]: GFP: rac1A | rac1A | increased filopodium formation | increased membrane ruffling | increased macropinocytosis | increased growth rate | increased cell motility |
DBS0351073 | [act15]: GFP: rac1A(G12V) | rac1A | decreased growth rate | decreased phagocytosis | aberrant cytokinesis | decreased macropinocytosis | decreased cell motility | delayed development | aberrant actin filament organization | abolished filopodium formation |
DBS0351075 | [act15]: GFP: rac1A(T17N) | rac1A | aberrant filopodium formation |
DBS0237703 | [act15]: GFP: rac1B | rac1B | increased filopodium formation | increased membrane ruffling |
DBS0237704 | [act15]: GFP: rac1C | rac1C | increased filopodium formation | increased membrane ruffling | increased growth rate | increased cell motility |
DBS0351074 | [act15]: GFP: rac1C(G12V) | rac1C | decreased growth rate | decreased phagocytosis | aberrant cytokinesis | decreased macropinocytosis | decreased cell motility | delayed development | aberrant actin filament organization | abolished filopodium formation |
DBS0351076 | [act15]: GFP: rac1C(T17N) | rac1C | aberrant filopodium formation |
DBS0237125 | [act15]: GFP: racG(1-168): racH(164-200) | racG | racH | increased filopodium formation | decreased actin filament polymerization | decreased phagocytosis |
DBS0237127 | [act15]: GFP: racH | racH | decreased pinocytosis | wild type | decreased phagocytosis | decreased growth rate | aberrant cytokinesis | aberrant cell morphology |
DBS0237128 | [act15]: GFP: racH(1-163): racG(167-201) | racG | racH | decreased actin filament polymerization |
DBS0237130 | [act15]: GFP: racH(M13V) | racH | increased actin filament polymerization | aberrant cytokinesis | aberrant cell morphology |
DBS0237132 | [act15]: GFP: racH(T18N) | racH | aberrant cytokinesis | aberrant cell morphology |
DBS0237133 | [act15]: GFP: racH: gemA(630-658) | gemA | racH | delayed cytokinesis |
DBS0238392 | [act15]: GFP: rapA | rapA | increased cell-substrate adhesion |
DBS0238393 | [act15]: GFP: rapA(G12V) | rapA | increased cell-substrate adhesion |
DBS0238394 | [act15]: GFP: rapA(S17N) | rapA | decreased cell-substrate adhesion |
DBS0350112 | [act15]: GFP: rheb(D60I) | rheb | increased phagocytosis |
DBS0350111 | [act15]: GFP: rheb(Q64L) | rheb | decreased phagocytosis |
DBS0237134 | [act15]: GFP: sbds | sbds | wild type |
DBS0237135 | [act15]: GFP: sbds | sbds | wild type |
DBS0351177 | [act15]: GFP: sey1 | sey1 | decreased defense response to Gram-negative bacterium | aberrant vacuole organization |
DBS0351178 | [act15]: GFP: sey1(K154A) | sey1 | increased defense response to Gram-negative bacterium | aberrant catalytic activity | decreased protein localization | aberrant endoplasmic reticulum organization |
DBS0350715 | [act15]: GFP: src1(2-646) | src1 | aberrant nuclear envelope morphology |
DBS0304563 | [act15]: GFP: sun1(283-905) | sun1 | increased number of centrosomes | decreased protein localization to nuclear envelope | aberrant nuclear membrane organization | aberrant nucleus morphology | increased vegetative cell size | aberrant centrosome localization | aberrant mitotic sister chromatid segregation |
DBS0350441 | [act15]: GFP: talA/ mhcA-/ talA- | mhcA | talA | aberrant protein localization |
DBS0350648 | [act15]: HA: Rab14(N121I) | rab14 | decreased pinocytosis | decreased hypotonic response | aberrant contractile vacuole morphology |
DBS0350899 | [act15]: HA: rab11(N126I) | rab11A | aberrant contractile vacuole organization | aberrant contractile vacuole morphology | increased phagocytosis |
DBS0350812 | [act15]: HA: rab7A(Q67L) | rab7A | increased exocytosis |
DBS0350813 | [act15]: HA: rab7A(T22N) | rab7A | decreased pinocytosis | increased secretion of lysosomal enzymes | decreased exocytosis | decreased phagocytosis | aberrant phagosome maturation | abolished macropinocytosis | abolished protein localization to phagocytic vesicle |
DBS0238111 | [act15]: HA: smkA | smkA | delayed development | decreased fruiting body size | decreased establishment of cell polarity | decreased chemotaxis to cAMP |
DBS0350429 | [act15]: RFP: abpE | abpE-1 | abpE-2 | delayed aggregation |
DBS0350867 | [act15]: RFP: mtpn | mtpn | increased filopodium formation | decreased protein localization to cell cortex | aberrant actin filament organization | decreased pseudopodium size |
DBS0351228 | [act15]: T7: rasG(G12T) | rasG | increased protein phosphorylation | decreased growth rate | decreased phagocytosis | increased cell-substrate adhesion | decreased filopodium formation |
DBS0351226 | [act15]: YFP: iqgC | iqgC | decreased phagocytosis | decreased macropinocytosis |
DBS0350986 | [act15]: YFP: myoC(G395A) | myoC | decreased pinocytosis | aberrant mitotic spindle organization | decreased phagocytosis |
DBS0237201 | [act15]: YFP: myoE | myoE | decreased pinocytosis | increased phagocytosis |
DBS0237817 | [act15]: YFP: wipA | wipA | increased filopodium formation | increased actin filament polymerization at leading edge |
DBS0237819 | [act15]: YFP: wipA(K36A) | wipA | increased filopodium formation | increased actin filament polymerization at leading edge |
DBS0237821 | [act15]: YFP: wipA(K93A/ S95A) | wipA | increased filopodium formation | increased actin filament polymerization at leading edge |
DBS0237227 | [act15]: [AS]dia2 | dia2 | aberrant extracellular cAMP signaling pathway | abolished aggregation | decreased cAMP level |
DBS0350673 | [act15]: abpC: GFP | abpC | decreased cell motility |
DBS0304574 | [act15]: abpD | abpD | abolished protein localization to nuclear envelope |
DBS0237096 | [act15]: abpE | abpE-1 | abpE-2 | aberrant aggregation | increased lateral pseudopodium formation | decreased cell motility | delayed development | decreased fruiting body size |
DBS0349940 | [act15]: acrA(1-731): YFP | acrA | aberrant spore coat morphology | decreased adenylate cyclase activity |
DBS0350292 | [act15]: act15(Y144W) | act15 | aberrant binding |
DBS0350800 | [act15]: adprt1A | adprt1A | increased gene expression | decreased gene expression | decreased ATP level | delayed aggregation | aberrant cell cycle | decreased growth rate | aberrant response to oxidative stress | increased mitochondrial fission | decreased cAMP level |
DBS0238086 | [act15]: atg1 | atg1 | wild type |
DBS0238091 | [act15]: atg1(1-628) | atg1 | wild type |
DBS0238088 | [act15]: atg1(K36A) | atg1 | abolished macroautophagy | increased number of autophagosomes | aberrant cellular response to nitrogen starvation | abolished aggregation |
DBS0238090 | [act15]: atg1(K36A/ 1-628) | atg1 | wild type |
DBS0350008 | [act15]: bzpN: GFP | bzpN | decreased growth rate | abolished negative regulation of vegetative growth |
DBS0237097 | [act15]: cak1: myc | cak1-1 | cak1-2 | aberrant DNA repair |
JK1 | [act15]: carA | carA-1 | carA-2 | delayed aggregation |
DBS0252737 | [act15]: carA(I104A) | carA-1 | carA-2 | decreased cAMP binding |
DBS0252732 | [act15]: carA(I104C) | carA-1 | carA-2 | decreased protein kinase activation |
DBS0252740 | [act15]: carA(I104D) | carA-1 | carA-2 | increased cAMP binding | delayed aggregation | aberrant oscillatory cAMP signaling | decreased protein kinase activation |
DBS0252744 | [act15]: carA(I104E) | carA-1 | carA-2 | increased cAMP binding | delayed aggregation | aberrant oscillatory cAMP signaling |
DBS0252741 | [act15]: carA(I104F) | carA-1 | carA-2 | increased cAMP binding | decreased protein kinase activation |
DBS0252738 | [act15]: carA(I104G) | carA-1 | carA-2 | increased cAMP binding | decreased protein kinase activation |
DBS0252747 | [act15]: carA(I104H) | carA-1 | carA-2 | development arrests at loose mound stage | increased cAMP binding | abolished oscillatory cAMP signaling | decreased protein kinase activation |
DBS0252749 | [act15]: carA(I104K) | carA-1 | carA-2 | increased cAMP binding | abolished oscillatory cAMP signaling | decreased protein kinase activation | abolished aggregation |
DBS0252739 | [act15]: carA(I104L) | carA-1 | carA-2 | wild type |
DBS0252742 | [act15]: carA(I104M) | carA-1 | carA-2 | increased cAMP binding |
DBS0252746 | [act15]: carA(I104N) | carA-1 | carA-2 | development arrests at loose mound stage | increased cAMP binding | abolished oscillatory cAMP signaling | decreased protein kinase activation |
DBS0252734 | [act15]: carA(I104P) | carA-1 | carA-2 | decreased protein kinase activation |
DBS0252745 | [act15]: carA(I104Q) | carA-1 | carA-2 | development arrests at loose mound stage | increased cAMP binding | abolished oscillatory cAMP signaling | decreased protein kinase activation |
DBS0252750 | [act15]: carA(I104R) | carA-1 | carA-2 | development arrests at loose mound stage | increased cAMP binding | abolished oscillatory cAMP signaling | decreased protein kinase activation |
DBS0252743 | [act15]: carA(I104S) | carA-1 | carA-2 | increased cAMP binding | aberrant oscillatory cAMP signaling | decreased protein kinase activation |
DBS0252735 | [act15]: carA(I104T) | carA-1 | carA-2 | increased cAMP binding | aberrant oscillatory cAMP signaling |
DBS0252736 | [act15]: carA(I104V) | carA-1 | carA-2 | wild type |
DBS0252733 | [act15]: carA(I104W) | carA-1 | carA-2 | increased cAMP binding |
DBS0252748 | [act15]: carA(I104Y) | carA-1 | carA-2 | development arrests at loose mound stage | increased cAMP binding | aberrant oscillatory cAMP signaling | decreased protein kinase activation |
DBS0351055 | [act15]: catA | catA | decreased slug migration | decreased fruiting body size | decreased superoxide generation | decreased sporulation |
DBS0351588 | [act15]: cdcD(E219K): RFP | cdcD | abolished catalytic activity |
DBS0350533 | [act15]: cdcD(R154C): RFP | cdcD | decreased catalytic activity | aberrant protein modification | decreased phototaxis |
DBS0350532 | [act15]: cdcD: RFP | cdcD | decreased protein level | increased catalytic activity | decreased growth rate |
DBS0237098 | [act15]: cdk5(D144N) | cdk5 | decreased pinocytosis | increased mound size | aberrant protein level | delayed aggregation | decreased phagocytosis | decreased growth rate | decreased sporulation | decreased protein secretion |
DBS0237099 | [act15]: cf60 | cf60 | increased number of mounds | aberrant mound size |
DBS0302445 | [act15]: cfaD | cfaD | decreased growth rate | aberrant fruiting body morphogenesis |
DBS0350333 | [act15]: cnrF: GFP | cnrF | aberrant regulation of GTPase activity |
DBS0302658 | [act15]: cnrN: myc/ smlA- | cnrN | smlA | decreased fruiting body size |
DBS0237102 | [act15]: cofA | cofA | increased actin bundle formation | increased membrane ruffling | increased cell motility |
DBS0350583 | [act15]: csaA | csaA | decreased cell-substrate adhesion | precocious aggregation | increased calcium-independent cell-cell adhesion |
DBS0350684 | [act15]: csaA(1-488): gppA(469-544) | csaA | gppA | aberrant protein localization to cell surface |
DBS0350642 | [act15]: cynA: GFP | cynA | aberrant cell motility | precocious aggregation | aberrant establishment or maintenance of cell polarity |
DBS0349864 | [act15]: cyrA: GFP | cyrA | increased chemotaxis to cAMP |
DBS0237104 | [act15]: dagA | dagA | wild type |
DBS0350978 | [act15]: deeJ | deeJ | increased pinocytosis | increased growth rate | increased phagocytosis |
DBS0237105 | [act15]: dgkA | dgkA | development arrests at loose mound stage | decreased chemotaxis rate | decreased myosin II assembly |
DBS0350946 | [act15]: dhcA(1384-4725) | dhcA | aberrant microtubule cytoskeleton organization |
DBS0237106 | [act15]: dhkC(394-661) | dhkC | development arrests at slug stage | increased slug migration |
DBS0235716 | [act15]: dhkK | dhkK | precocious aggregation | development arrests at mound stage |
DBS0235705 | [act15]: dhkK(D1125N) | dhkK | aberrant extracellular cAMP signaling pathway | delayed development |
DBS0235707 | [act15]: dhkK(H825Q) | dhkK | precocious development | decreased fruiting body size |
DBS0235709 | [act15]: dhkK(H825Q/ D1125N) | dhkK | aberrant slug migration | delayed culmination |
DBS0237107 | [act15]: dng1 | dng1 | aberrant extracellular cAMP signaling pathway | decreased growth rate | precocious aggregation |
DBS0351565 | [act15]: eIF6 | eIF6 | aberrant cellular process |
DBS0350396 | [act15]: eif2s1(S53A) | eif2s1 | aberrant spore morphology | decreased spore germination | decreased protein level |
DBS0350424 | [act15]: eif2s1(S53A)/ [bzpR]: lacZ | eif2s1 | abolished translation |
DBS0237562 | [act15]: enlA(92-497) | enlA | decreased cell-substrate adhesion |
DBS0237108 | [act15]: fbxA: FLAG | fbxA | decreased prespore cell differentiation |
DBS0350365 | [act15]: fip(1163-2038) | fip-1 | fip-2 | aberrant prestalk O cell differentiation |
DBS0237109 | [act15]: fps | fps | increased resistance to alendronic acid |
DBS0350012 | [act15]: fps: GFP | fps | increased resistance to alendronic acid |
DBS0235979 | [act15]: fszA: GFP | fszA | aberrant mitochondrion morphology |
DBS0351485 | [act15]: fszB: GFP | fszB | decreased mitochondrial fusion | decreased mitochondrial fission |
DBS0349956 | [act15]: fttB(K49E): GFP | fttB | aberrant cytoskeleton organization |
DBS0237601 | [act15]: gbpD | gbpD | aberrant aggregation | decreased cell-cell adhesion | increased guanyl-nucleotide exchange factor activity | increased cell-substrate adhesion | decreased chemotaxis to cAMP | aberrant cell morphology | increased pseudopodium formation |
DBS0351056 | [act15]: gcsA | gcsA | increased catalytic activity | decreased slug migration | aberrant gene expression | decreased fruiting body size | decreased superoxide generation | decreased sporulation |
DBS0237136 | [act15]: gpaA | gpaA | increased stalk length | aberrant cytokinesis | aberrant fruiting body morphogenesis |
DBS0351058 | [act15]: gpaB | gpaB | aberrant aggregation | abolished sporulation | development arrests at mound stage | increased cAMP level | aberrant actin filament polymerization | decreased establishment of cell polarity | aberrant protein localization to plasma membrane | increased prestalk cell differentiation |
DBS0350680 | [act15]: gpaE | gpaE | abolished vegetative growth | decreased chemotaxis to folate |
DBS0237145 | [act15]: gpaG | gpaG | aberrant fruiting body morphogenesis |
DBS0237146 | [act15]: gpaH | gpaH | wild type |
DBS0350971 | [act15]: gpaH/ AX2 | gpaH | aberrant cytokinesis | decreased growth rate | aberrant spore germination | aberrant sorocarp development | increased cell-substrate adhesion | increased cell-cell adhesion |
DBS0237147 | [act15]: gpaI(G38V): FLAG | gpaI | increased mound size | delayed aggregation | decreased number of mounds | aberrant fruiting body morphogenesis |
DBS0237148 | [act15]: gpaI(Q196L): FLAG | gpaI | increased oscillatory cAMP signaling | decreased protein localization to plasma membrane | increased mound size | aberrant activation of adenylate cyclase activity | increased chemotaxis to cAMP | increased lateral pseudopodium formation | delayed aggregation | decreased number of mounds | increased actin filament polymerization | aberrant adaptation of signaling pathway | aberrant fruiting body morphogenesis | decreased establishment of cell polarity | decreased cGMP biosynthesis |
DBS0350079 | [act15]: grlB | grlB | delayed aggregation |
DBS0237149 | [act15]: grxA | grxA | decreased prespore gene expression | delayed culmination |
DBS0237151 | [act15]: grxA(C21S) | grxA | wild type |
DBS0237152 | [act15]: grxA/ [act15]: lacZ | grxA | increased cell migration to prestalk region |
DBS0351054 | [act15]: gshB | gshB | aberrant aggregation | abolished sporulation | increased gene expression | development arrests at mound stage | increased cAMP level | aberrant actin filament polymerization | decreased establishment of cell polarity |
DBS0351059 | [act15]: gshB/ [AS]gpaB | gpaB | gshB | aberrant stream morphology | decreased establishment of cell polarity | decreased sporulation |
DBS0237153 | [act15]: gsr | gsr | increased cell migration to prestalk region | delayed culmination |
DBS0350989 | [act15]: gst4 | gst4 | increased fruiting body size |
DBS0236152 | [act15]: hcpA(1-161: 218-225): GFP | hcpA | decreased growth rate |
DBS0236159 | [act15]: hcpB(1-197: 237-244): GFP | hcpB | decreased growth rate |
DBS0351607 | [act15]: hsp101(K213A) | hsp101 | decreased cellular thermotolerance |
DBS0351608 | [act15]: hsp101(K613A) | hsp101 | decreased cellular thermotolerance |
DBS0252821 | [act15]: hssA | hssA | wild type |
DBS0351173 | [act15]: htrA(S300A) | htrA | decreased growth rate | aberrant fruiting body morphogenesis |
DBS0351282 | [act15]: htt: eYFP | htt | decreased gene expression | increased gene expression |
DBS0350397 | [act15]: ifkA(881-1514(K1258G,F1320L)) | ifkA | decreased growth rate | increased protein level |
DBS0350037 | [act15]: mekA(299-360) | mekA | decreased mound size |
DBS0350034 | [act15]: mekA(K321A) | mekA | decreased mound size |
DBS0350033 | [act15]: mekA(S444A/ T448A) | mekA | decreased mound size |
DBS0237203 | [act15]: mhkB: FLAG | mhkB | aberrant cytokinesis | decreased myosin II assembly |
DBS0350026 | [act15]: mip1/ [act15]: mekA: FLAG | mekA | mip1-1 | mip1-2 | aberrant protein localization to nucleus |
DBS0237157 | [act15]: mkkA | mkkA | development arrests at mound stage | delayed development |
DBS0237158 | [act15]: mkkA(K199A) | mkkA | precocious development | decreased sporulation |
DBS0237159 | [act15]: mkkA{deltaWD40} | mkkA | development arrests at mound stage | aberrant fruiting body morphogenesis | delayed development |
DBS0350331 | [act15]: mkpA: GFP: TAP | mkpA | increased resistance to cisplatin |
DBS0350332 | [act15]: mkpB(C294V) | mkpB-1 | mkpB-2 | decreased migratory slug size | delayed prestalk gene expression | delayed prespore gene expression | aberrant sorocarp development | decreased resistance to cisplatin |
DBS0350330 | [act15]: mkpB: GFP: TAP | mkpB-1 | mkpB-2 | increased resistance to cisplatin |
DBS0237160 | [act15]: mtaA(1-813)/ [dscB]tubA: GFP | cepJ | aberrant microtubule cytoskeleton organization |
DBS0237162 | [act15]: myc-cdk8 | cdk8 | increased number of tip-organizers | precocious development of tipped mound |
DBS0350050 | [act15]: myc: cdk8/ [act15]: FLAG: cycC | cdk8 | cycC | precocious development of tipped mound |
DBS0266837 | [act15]: myc: ptpC | ptpC | abolished protein localization to nucleus | aberrant hyperosmotic response | aberrant signal transduction |
DBS0350417 | [act15]: myc: ptpC | ptpC | aberrant protein phosphorylation |
DBS0266839 | [act15]: myc: ptpCΔ(C649S) | ptpC | aberrant protein localization to nucleus | increased protein tyrosine phosphorylation |
DBS0266838 | [act15]: myc: ptpC(C649S) | ptpC | aberrant protein localization to nucleus | increased protein tyrosine phosphorylation |
DBS0238398 | [act15]: myc: rapA | rapA | increased cell-substrate adhesion | decreased cell motility | aberrant cell morphology |
DBS0238396 | [act15]: myc: rapA(G12V) | rapA | increased protein localization to cell cortex | delayed aggregation | increased cell-substrate adhesion | decreased cell motility | increased protein kinase activation |
DBS0238397 | [act15]: myc: rapA(S17N) | rapA | decreased cell-substrate adhesion |
DBS0237167 | [act15]: myc: rckA | rckA | delayed development |
DBS0237163 | [act15]: myc: rckA(C551A) | rckA | delayed slug development | decreased chemotaxis rate |
DBS0237164 | [act15]: myc: rckA(E510G) | rckA | delayed slug development | decreased chemotaxis rate |
DBS0237165 | [act15]: myc: rckA(E510G/ N511A) | rckA | delayed slug development | decreased chemotaxis rate |
DBS0237166 | [act15]: myc: rckA(K867A) | rckA | precocious aggregation | delayed slug development | decreased chemotaxis rate |
DBS0350132 | [act15]: myc: splB | splB | increased protein localization to nucleus | increased protein tyrosine phosphorylation |
DBS0351051 | [act15]: myc: talA(2255-2492)/ puf118(677-1036) | puf118 | talA | aberrant chemotaxis to cAMP | abolished protein localization to leading edge |
DBS0351359 | [act15]: myoB | myoB | decreased pinocytosis | increased protein localization to cell cortex | delayed aggregation | decreased growth rate | decreased cell motility | delayed development | decreased fruiting body size | aberrant actin filament organization |
DBS0351037 | [act15]: myoE(1-1005) | myoE | abolished phosphatidylinositol binding |
DBS0351036 | [act15]: myoE(K859A/ K863A/ R868A/ R869A): GFP | myoE | abolished phosphatidylinositol binding | abolished protein localization to plasma membrane |
DBS0349847 | [act15]: myoK: Myc | myoK | decreased phagocytosis |
DBS0237175 | [act15]: myoM | myoM | aberrant stream morphology | delayed development | increased pseudopodium size |
DBS0237178 | [act15]: myoM-Mtail | myoM | decreased growth rate | aberrant hypotonic response | aberrant stream morphology | aberrant hyperosmotic response | delayed development | increased pseudopodium size |
DBS0237179 | [act15]: myr: rckA | rckA | delayed development | decreased chemotaxis rate |
DBS0349860 | [act15]: ndkC | ndkC-1 | ndkC-2 | decreased exocytosis | decreased pinocytosis | decreased phagocytosis | decreased growth rate | increased growth rate |
DBS0237180 | [act15]: nramp1: GFP | nramp1 | increased defense response to Gram-negative bacterium | increased iron ion transport |
DBS0350858 | [act15]: odc | odc | aberrant cellular metabolic process | aberrant cell cycle |
DBS0351201 | [act15]: odc: eYFP | odc | decreased growth rate | delayed development |
DBS0237182 | [act15]: pakA | pakA | wild type |
DBS0237183 | [act15]: pakA(K394A) | pakA | development arrests at mound stage | delayed development |
DBS0237184 | [act15]: pakA[CA] | pakA | abolished aggregation |
DBS0237185 | [act15]: pakA[G+K] | pakA | wild type |
DBS0349855 | [act15]: pakB(1-337: 563-852) | pakB | decreased phagocytosis |
DBS0350901 | [act15]: pdeE: YFP | pdeE | development arrests at loose mound stage | decreased oscillatory cAMP signaling |
DBS0351186 | [act15]: phr2ab: GFP | phr2aB | aberrant cytokinesis | aberrant centrosome organization |
DBS0349903 | [act15]: pisA | pisA | aberrant development of tipped mound | decreased slug migration | delayed aggregation | decreased fruiting body size |
DBS0349902 | [act15]: pisA: GFP | pisA | decreased slug migration | increased gene expression | decreased gene expression | delayed aggregation | delayed development | decreased phototaxis |
DBS0350693 | [act15]: pkaC | pkaC | precocious development |
DBS0237188 | [act15]: pkaC(1-497) | pkaC | precocious development | decreased fruiting body size | decreased cAMP level |
DBS0235418 | [act15]: pkaR | pkaR | aberrant response to abiotic stimulus |
DBS0237189 | [act15]: pkaR(G135E/ G261A) | pkaR | decreased protein tyrosine phosphorylation | decreased protein kinase activity | abolished cAMP binding | abolished oscillatory cAMP signaling | abolished aggregation |
DBS0350701 | [act15]: pkaR(G135E/ G261A)/ AX3 | pkaR | decreased gene expression | abolished oscillatory cAMP signaling |
DBS0350609 | [act15]: pkaR(S133T,G135E) | pkaR | decreased cAMP binding | decreased protein kinase activity | abolished oscillatory cAMP signaling | abolished aggregation |
DBS0350920 | [act15]: pkcA | pkcA | increased catalytic activity | abolished aggregation |
DBS0235538 | [act15]: pldB | pldB | increased catalytic activity | increased exocytosis | decreased actin filament polymerization | aberrant chemotaxis to cAMP | abolished aggregation | decreased sporulation |
DBS0349874 | [act15]: psaA: GFP | psaA | aberrant sporulation |
DBS0351577 | [act15]: psiA | psiA | decreased prespore gene expression | decreased stalk cell differentiation |
DBS0351579 | [act15]: psiA/ [cudA]: lacZ | psiA | aberrant prespore gene expression |
DBS0351580 | [act15]: psiA/ [ecmB]: lacZ | psiA | delayed prestalk gene expression |
DBS0350751 | [act15]: pten(16-515): GFP | pten | abolished catalytic activity |
DBS0350750 | [act15]: pten(186-515): GFP | pten | abolished catalytic activity |
DBS0350752 | [act15]: pten(C124S): GFP | pten | abolished catalytic activity |
DBS0350753 | [act15]: pten(G129E): GFP | pten | abolished catalytic activity |
DBS0350318 | [act15]: rab11A: RFP | rab11A | aberrant contractile vacuole organization | decreased contractile vacuole size | abolished hypotonic response |
DBS0350951 | [act15]: rac1B(Q61L) | rac1B | increased lateral pseudopodium formation | decreased chemotaxis to cAMP | aberrant actin filament organization |
DBS0350952 | [act15]: rac1B(T17N) | rac1B | abolished establishment of cell polarity | delayed aggregation | aberrant actin filament organization | abolished chemotaxis to cAMP |
DBS0350469 | [act15]: racE(G20V): GFP | racE | decreased actin filament polymerization | aberrant cytokinesis | decreased growth rate |
DBS0350584 | [act15]: rapA(G12V) | rapA | abolished protein localization to nucleus | increased protein localization to cell cortex | aberrant nucleus morphology | decreased growth rate | aberrant cytokinesis | increased cell-substrate adhesion | abolished protein localization to centrosome | increased number of microtubule organizing center |
DBS0351497 | [act15]: rasD(Q61L) | rasD | decreased protein kinase activation |
DBS0351496 | [act15]: rasD(S17N) | rasD | increased protein kinase activation |
DBS0351212 | [act15]: rasG(S17N) | rasG | aberrant activation of GTPase activity | decreased chemotaxis to cAMP |
DBS0350262 | [act15]: rbg3 | rbg3 | increased lysosome size | decreased growth rate | delayed development |
DBS0237192 | [act15]: rblA | rblA | delayed mitotic cell cycle |
DBS0350671 | [act15]: regA(126-316): myc | regA | precocious sporulation |
DBS0349938 | [act15]: rgaA | rgaA | decreased actin filament polymerization | aberrant cytokinesis | decreased cell motility |
DBS0351529 | [act15]: rgbA(751-1072,1080-1284,1517-1846) | rgbA | aberrant macropinocytosis | abolished protein localization to macropinosome |
DBS0351528 | [act15]: rgbA(751-1072,1121-1317,1505-1834) | rgbA | aberrant macropinocytosis | abolished protein localization to macropinosome |
DBS0351304 | [act15]: rheb | rheb | decreased phagocytosis | decreased macropinocytosis | increased growth rate |
DBS0350294 | [act15]: rheb: YFP | rheb | increased vegetative cell size |
DBS0350890 | [act15]: rnp1A | rnp1A | increased resistance to nocodazole |
DBS0350575 | [act15]: rps4 | rps4 | decreased spore germination | aberrant actin cytoskeleton organization | aberrant vegetative growth | decreased mound size | decreased spore size | aberrant fruiting body morphogenesis | decreased sporulation |
DBS0236915 | [act15]: rzpA | rzpA | increased prestalk gene expression | decreased prespore gene expression | delayed culmination |
DBS0349793 | [act15]: sadA(921-952) | sadA | decreased cell-substrate adhesion |
SA604 | [act15]: sgkA: FLAG | sgkA | aberrant response to abiotic stimulus | increased resistance to cisplatin | aberrant cytokinesis | increased resistance to carboplatin |
DBS0304461 | [act15]: sir2E | sir2E | increased growth rate |
HPF437 | [act15]: snfA(1-379): GFP | snfA | increased stalk width | increased ATP level | decreased growth rate | increased number of mitochondria | decreased defense response to bacterium | decreased phototaxis | decreased stalk length | aberrant mitochondrion organization |
DBS0351040 | [act15]: snfA(1-379): GFP/ [AS]ndkC-1 | ndkC-1 | ndkC-2 | snfA | wild type |
DBS0350976 | [act15]: snfA: YFP | snfA | decreased growth rate | aberrant fruiting body morphogenesis |
DBS0351053 | [act15]: sod2 | sod2 | decreased slug migration | decreased fruiting body size | decreased superoxide generation | decreased sporulation |
DBS0304457 | [act15]: sodA/ gcsA- | gcsA | sodA | wild type |
DBS0237194 | [act15]: sodA: myc | sodA | aberrant response to abiotic stimulus | decreased gene expression | abolished aggregation |
DBS0237195 | [act15]: spkA: FLAG | spkA-1 | spkA-2 | aberrant aggregation | decreased chemotaxis rate | aberrant actin filament organization | decreased establishment of cell polarity |
AK1209 | [act15]: tagA(1-890) | tagA | increased number of mound tips |
DBS0350962 | [act15]: tor(212-2380): YFP | tor | decreased growth rate | aberrant sorocarp development |
DBS0237198 | [act15]: torA | torA | abolished vegetative growth |
DBS0350862 | [act15]: tpt1: YFP | tpt1 | decreased gene expression | decreased growth rate | decreased number of mounds | delayed development | aberrant fruiting body morphogenesis |
DBS0237199 | [act15]: trrA | trrA | aberrant aggregation | decreased growth rate | decreased phagocytosis | delayed culmination |
DBS0351572 | [act15]: vacA: GFP | vacA | decreased phagocytosis |
DBS0351573 | [act15]: vacB: GFP | vacB | decreased phagocytosis |
DBS0351574 | [act15]: vacC: GFP | vacC | decreased phagocytosis |
DBS0237200 | [act15]: vasP | vasP | increased filopodium formation | increased actin filament polymerization |
DBS0351184 | [act15]: washc5(N457D): GFP | washc5 | aberrant cytokinesis |
DBS0351183 | [act15]: washc5: GFP | washc5 | aberrant cytokinesis |
DBS0350911 | [act6]: GFP: cepA/ cepA(183-346) | cepA | increased number of centrosomes |
DBS0237209 | [act6]: GFP: cepJ | cepJ | decreased resistance to nocodazole | aberrant cytokinesis | decreased size of astral microtubules | decreased number of astral microtubules | increased number of microtubule organizing center |
DBS0351235 | [act6]: GFP: cepL | cepL | increased number of microtubule organizing center |
DBS0351586 | [act6]: GFP: gefQ(S431A) | gefQ | increased number of mound tips | delayed development |
DBS0349984 | [act6]: GFP: lmnB(1-712) | lmnB | aberrant cellular response to fluid shear stress | aberrant intermediate filament organization | abolished vegetative growth |
DBS0351551 | [act6]: GFP: lmnB(1-712)/ S122A | lmnB | aberrant intermediate filament bundle assembly |
DBS0350497 | [act6]: GFP: rab2A | rab2A | decreased pinocytosis | decreased phagocytosis | aberrant hypotonic response | increased growth rate |
DBS0350498 | [act6]: GFP: rab2A(N118I) | rab2A | aberrant cell-cell adhesion | aberrant hypotonic response | increased growth rate | precocious development |
DBS0350499 | [act6]: GFP: rab2A(Q64L) | rab2A | decreased autophagic cell death | aberrant cell-cell adhesion | aberrant sorocarp development | aberrant hypotonic response | increased growth rate | increased phagocytosis |
DBS0306243 | [act6]: GFP: sun1 | sun1 | increased number of centrosomes | aberrant nucleus morphology | aberrant mitotic sister chromatid segregation | aberrant centromere complex assembly | aberrant centrosome organization |
DBS0306244 | [act6]: GFP: sun1(1-722) | sun1 | increased number of centrosomes | aberrant nucleus morphology | aberrant mitotic sister chromatid segregation | aberrant centromere complex assembly | aberrant centrosome organization |
DBS0235563 | [act6]: abpD(33-262) | abpB | decreased growth rate | delayed development |
DBS0237204 | [act6]: canA | canA | wild type |
DBS0350685 | [act6]: csaA | csaA | increased migratory slug size | increased calcium-independent cell-cell adhesion |
DBS0237205 | [act6]: dia1 | dia1 | delayed aggregation |
DBS0236905 | [act6]: mrps4 | mrps4 | precocious aggregation |
DBS0235444 | [act6]: myc: eppA(S250A) | eppA | decreased growth rate | delayed development | decreased cAMP level |
DBS0235445 | [act6]: myc: eppA(S325A) | eppA | decreased growth rate |
DBS0266836 | [act6]: ptpB | ptpB | delayed aggregation | decreased fruiting body size |
DBS0237218 | [act6]: ptpC | ptpC | increased mound size | decreased growth rate |
DBS0237219 | [act6]: ptpC(C649S) | ptpC | increased mound size | decreased growth rate |
DBS0350807 | [act6]: rabS(N137I): GFP | rabS | increased secretion of lysosomal enzymes | aberrant contractile vacuole organization | increased endocytic recycling |
DBS0350806 | [act6]: rabS: GFP | rabS | decreased cell-cell adhesion | increased secretion of lysosomal enzymes | increased cell death | increased pinocytosis | aberrant sorocarp development | aberrant hyperosmotic response | decreased chemotaxis to cAMP | increased growth rate | increased phagocytosis |
DBS0350982 | [act6]: rps6 | rps6 | aberrant cytokinesis | delayed development |
DBS0304410 | [act6]: srsA | srsA | increased migratory slug size | increased mound size | decreased gene expression | delayed aggregation | aberrant fruiting body morphogenesis | decreased sporulation |
DBS0237220 | [act6]: trap1 | trap1 | development arrests at loose mound stage | aberrant aggregation | abolished pinocytosis | increased gene expression | decreased gene expression | decreased growth rate |
DBS0350695 | [act6]: yakA | yakA | increased gene expression | abolished vegetative growth |
DBS0350069 | [act6]: zizB: GFP | zizB | aberrant cell separation during cytokinesis | increased filopodium formation |
DBS0304460 | [act]: alrA/ gcsA- | alrA | gcsA | wild type |
DBS0349955 | [ampA]: RFP: ampA | ampA | development arrests at mound stage |
DBS0237221 | [arkA]: arkA: myc2 | arkA | aberrant aggregation |
HM2191 | [arpB]: arpB: GFP | arpB | decreased actin filament polymerization | decreased cell-substrate adhesion | decreased growth rate | decreased cell motility | decreased chemotaxis rate | increased bleb assembly |
DBS0235407 | [carA]: carA(1-317) | carA-1 | carA-2 | delayed development |
DBS0351495 | [cotB]: FLAG: fbxD | fbxD | delayed culmination |
HW358 | [cotB]: fpaB: myc | fpaB-1 | fpaB-2 | increased response to hypoxia |
DBS0350705 | [cotC]: pkaC | pkaC | aberrant sorocarp development | aberrant fruiting body morphogenesis | precocious development |
DBS0350706 | [cotC]: pkaC/ [spiA]: lacZ | pkaC | spiA | precocious gene expression |
DBS0350048 | [cycC]: cycC: TAP | cycC | decreased protein level |
DBS0350942 | [disc]: HA: rab14(N121I) | rab14 | decreased endosomal vesicle fusion | decreased phagocytosis |
DBS0350941 | [disc]: HA: rab14(Q67L) | rab14 | increased lysosome size | increased endosomal vesicle fusion | increased phagocytosis |
DBS0351493 | [dscA]: His: agtA | agtA | decreased sporulation |
DBS0351492 | [dscA]: His: agtA(D132A) | agtA | aberrant stalk morphogenesis | abolished sporulation |
DBS0237238 | [dscB]: GFP: rab8A | rab8A | wild type |
DBS0237239 | [dscB]: GFP: rab8A(N128I) | rab8A | increased mound size | increased cell-cell adhesion | decreased fruiting body size |
DBS0237240 | [dscB]: GFP: rab8A(Q74L) | rab8A | abolished aggregation | aberrant cytoskeleton organization |
DBS0237241 | [dscB]: GFP: rab8B | rab8B | increased mound size |
DBS0237242 | [dscB]: GFP: rab8B(Q74L) | rab8B | increased mound size |
DBS0305081 | [dscB]: GFP: vamp7A(L35A) | vamp7A | increased protein localization to plasma membrane |
DBS0351106 | [dscB]: HA: racC | racC | decreased exocytosis | decreased pinocytosis | decreased macropinocytosis | aberrant actin filament organization | increased phagocytosis |
DBS0350903 | [dscB]: HA: rapB(G12V) | racB | decreased exocytosis | decreased phagocytosis | aberrant cytokinesis | decreased growth rate | decreased macropinocytosis | aberrant actin filament organization | aberrant cell morphology |
DBS0350433 | [dscB]: abpB(E60K): GFP | abpB | abolished actin filament polymerization |
DBS0350820 | [dscB]: cafA | cafA | increased gene expression | precocious development |
DBS0237237 | [dscB]: cycB(106-436) | cycB | mitotic M phase arrest |
DBS0350922 | [dscB]: dicA(1-278) | dicA | increased cell death | abolished protein binding | aberrant microtubule cytoskeleton organization | aberrant Golgi localization | aberrant mitotic sister chromatid segregation | aberrant centrosome organization |
DBS0350923 | [dscB]: dicA(48-654) | dicA | aberrant microtubule cytoskeleton organization | aberrant Golgi localization | decreased protein binding | aberrant mitotic sister chromatid segregation | aberrant centrosome organization |
DBS0237243 | [dscB]: myc: rac1B | rac1B | increased rate of endocytosis | aberrant cytokinesis | decreased growth rate | delayed development |
DBS0237244 | [dscB]: myc: rac1B(G12V) | rac1B | decreased rate of endocytosis | decreased growth rate | abolished aggregation | aberrant cell morphology |
DBS0237245 | [dscB]: myc: rac1B(Q61L) | rac1B | decreased rate of endocytosis | decreased growth rate | abolished aggregation | aberrant cell morphology |
DBS0237246 | [dscB]: myc: rac1B(T17N) | rac1B | decreased rate of endocytosis | decreased growth rate | abolished aggregation |
DBS0351510 | [dscB]: rac1B(G12V): myc | rac1B | decreased pinocytosis | decreased growth rate | aberrant cytokinesis | delayed development | aberrant actin filament organization | aberrant cell morphology |
DBS0351511 | [dscB]: rac1B(Q61L): myc | rac1B | decreased growth rate | aberrant cytokinesis | delayed development | aberrant actin filament organization | aberrant cell morphology |
DBS0351512 | [dscB]: rac1B(T17N): myc | rac1B | decreased pinocytosis | decreased growth rate | aberrant cytokinesis | decreased chemotaxis to folate | delayed development | aberrant actin filament polymerization | aberrant cell morphology |
DBS0350589 | [dscB]: rapA | rapA | decreased pinocytosis | aberrant actin filament organization | aberrant cell morphology | increased phagocytosis |
DBS0350586 | [dscB]: rapA(D40E) | rapA | aberrant actin filament organization | aberrant cell morphology |
DBS0350588 | [dscB]: rapA(F160L) | rapA | aberrant actin filament organization | aberrant cell morphology |
DBS0350590 | [dscB]: rapA(G12T) | rapA | decreased pinocytosis | increased phagocytosis |
DBS0237247 | [dscB]: rapA(G12V) | rapA | aberrant osmosensory signaling pathway | aberrant actin filament organization | aberrant cell morphology |
DBS0350585 | [dscB]: rapA(S19N) | rapA | decreased phagocytosis | aberrant cell morphology |
DBS0350587 | [dscB]: rapA(T63Q) | rapA | aberrant cell morphology |
DBS0237248 | [dscB]: rasG(G12T) | rasG | decreased gene expression | decreased growth rate | increased cell-cell adhesion | decreased cell motility | decreased protein kinase activation | decreased fruiting body size | abolished aggregation | aberrant cell morphology | decreased sporulation |
DBS0351227 | [dscB]: rasG(G12T/ T45Q) | rasG | wild type | aberrant cell morphology |
DBS0350933 | [dscC]: kif2 | kif2 | aberrant cell cycle |
DBS0351230 | [ecmAO]: rasG(G12T) | rasG | aberrant prestalk gene expression | aberrant culmination |
DBS0350703 | [ecmA]: pkaC | pkaC | development arrests at mound stage | abolished development of tipped mound |
DBS0350659 | [ecmA]: pkaC(9-648) | pkaC | development arrests at tipped mound stage |
DBS0350699 | [ecmA]: pkaR(G135E/ G261A) | pkaR | decreased migratory slug size | delayed development of tipped mound | aberrant culmination | aberrant slug migration | decreased prestalk gene expression | increased slug migration | aberrant prestalk cell differentiation |
DBS0350700 | [ecmA]: pkaR(G135E/ G261A)/ [ecmB-frag]: lacZ | pkaR | abolished stalk cell differentiation |
DBS0350704 | [ecmB]: pkaC | pkaC | development arrests at mound stage | abolished development of tipped mound |
DBS0350639 | [ecmF]: expl3: myc | expl3 | aberrant stalk morphogenesis | delayed slug development |
DBS0304865 | [expl7]: expl7: GFP | expl7 | aberrant late culminant morphology |
DBS0237252 | [gpaA]: gpaA(G45V) | gpaA | delayed development |
DBS0237253 | [gpaA]: gpaA(Q206L) | gpaA | increased basal disc size |
DBS0237254 | [gpaB]: gpaB(Q208L) | gpaB | aberrant protein localization to plasma membrane |
DBS0237255 | [hairpin]dct | dct | aberrant cytokinesis | aberrant pseudopodium formation |
DBS0238412 | [inviable]arcB- | arcB | abolished vegetative growth |
DBS0238407 | [inviable]arpB- | arpB | abolished vegetative growth |
DBS0237257 | [inviable]cofA- | cofA | abolished vegetative growth |
DBS0349945 | [inviable]fttB | fttB | abolished vegetative growth |
DBS0349872 | [inviable]lkb1- | lkb1 | abolished vegetative growth |
DBS0237265 | [inviable]phlp2- | phlp2 | abolished vegetative growth |
DBS0349948 | [ndm]: ndm: RFP | ndm | development arrests at mound stage |
DBS0236086 | [pdsA-agg]: pdsA | pdsA | precocious development |
DBS0236111 | [pdsA-ldev]: pdsA | pdsA | development arrests at mound stage |
DBS0236484 | [pkaC]: pkaC | pkaC | increased gene expression | precocious prespore gene expression | decreased spore cell differentiation | aberrant fruiting body morphogenesis | precocious development | precocious gene expression | decreased cAMP level |
DBS0350709 | [pkaC]: pkaC/ [dscC]: lacZ | dscC-1 | dscC-2 | pkaC | aberrant gene expression |
DBS0350196 | [pkaC]: pkaC/ nsfA(A1854T,T1984A,C2131A,A2398T,T2574A) | nsfA | pkaC | decreased spore cell differentiation |
DBS0350696 | [pkaC]: pkaC/ srfA- | pkaC | srfA | aberrant spore coat morphology | aberrant gene expression |
DBS0237289 | [psmC1]: psmC1 | psmC1 | delayed development of tipped mound | aberrant cytokinesis | delayed gene expression |
DBS0349928 | [pspA]: lacZ | pspA | aberrant prespore gene expression |
DBS0350658 | [pspA]: pkaC(9-648) | pkaC | precocious sporulation | aberrant fruiting body morphogenesis |
DBS0350697 | [pspA]: pkaR(G135E/ G261A) | pkaR | abolished gene expression | decreased prespore gene expression | aberrant sorus color |
DBS0351229 | [pspA]: rasG(G12T) | rasG | increased number of mound tips | increased prestalk gene expression | decreased prespore gene expression | abolished phototaxis | increased prestalk cell differentiation |
DBS0237290 | [ptpA1]: ptpA1 | ptpA1-1 | ptpA1-2 | delayed aggregation | decreased growth rate | aberrant fruiting body morphogenesis |
DBS0237291 | [ptpB]ptpB | ptpB | decreased growth rate | development arrests at mound stage |
DBS0351231 | [rasD]: rasG(G12T) | rasG | development arrests at loose mound stage | increased number of mound tips |
DBS0236867 | [rasG]: rasG(G12T) | rasG | aberrant aggregation |
SA601 | [sglA-myc]neoR-1 | sglA | decreased resistance to carboplatin | decreased growth rate | aberrant cytokinesis | decreased resistance to cisplatin |
DBS0237316 | [tet]: GFP(S65T): racG(G12V) | racG | increased filopodium formation | decreased positive regulation of GTPase activity | decreased actin filament polymerization | increased phagocytosis | abolished chemotaxis to cAMP |
DBS0237317 | [tet]: GFP(S65T): racG(T17N) | racG | abolished actin filament polymerization | abolished chemotaxis to cAMP |
DBS0350110 | [tet]: RNAi: raptor | raptor | decreased growth rate |
DBS0238351 | [tet]: [RNAi]cinC | cinC | decreased translation | precocious aggregation | decreased growth rate |
DBS0237318 | [tet]: pten | pten | decreased cell motility | decreased protein kinase activation |
DBS0237622 | [tet]: rapA(S17N)/ [act15]: gbpD | gbpD | rapA | increased establishment of cell polarity | increased cell-substrate adhesion | aberrant cell morphology |
DBS0351461 | [tet]rasD(G12T) | rasD | increased gene expression | increased prestalk cell differentiation |
DBS0351463 | [tet]rasD(G12T)/ rigA- | rasD | rigA | wild type |
DBS0350494 | [tgrB1]: [RNAi]abcB3/ [tgrC1]: GFP | abcB3 | delayed development | decreased cAMP level |
DBS0351290 | [tre]: drkA: myc | drkA | decreased growth rate | increased protein tyrosine phosphorylation |
DBS0304911 | [tre]: paxB | paxB | abolished sporulation | aberrant endocytosis | decreased cell-substrate adhesion | aberrant chemotaxis to folate | development arrests at mound stage | decreased cell motility | increased cell-cell adhesion |
DBS0350267 | [tre]: secG | secG | increased filopodium formation | abolished establishment of cell polarity | development arrests at mound stage | aberrant actin cytoskeleton organization | aberrant actin filament polymerization | abolished chemotaxis to cAMP | delayed gene expression |
DBS0351555 | [unk]: FLAG: rab1A(Q67L) | rab1A | aberrant actin filament polymerization | aberrant pseudopodium formation |
DBS0351556 | [unk]: FLAG: rab1A(S22N) | rab1A | decreased actin filament polymerization | decreased chemotaxis to cAMP |
DBS0351442 | [unk]: GFP: RasG | rasG | increased macropinocytosis |
DBS0351443 | [unk]: GFP: RasG(G12T) | rasG | increased macropinocytosis |
DBS0351444 | [unk]: GFP: RasS | rasS | increased macropinocytosis |
DBS0351445 | [unk]: GFP: RasS(G12V) | rasS | increased macropinocytosis |
DBS0350726 | [unk]: GFP: cepE | cepE | increased number of centrosomes | aberrant cytokinesis |
DBS0351454 | [unk]: GFP: piaA(G963E) | piaA | delayed aggregation | decreased protein binding |
DBS0351507 | [unk]: GFP: wasA(I173A/ F179A) | wasA | abolished protein binding |
DBS0350447 | [unk]: PTEN(H385G/ N389A/ H390A) | pten | decreased protein localization to plasma membrane | decreased fruiting body size |
DBS0351270 | [unk]: gpgA(1-65) | gpgA | decreased protein localization to plasma membrane | abolished aggregation | aberrant actin filament organization | abolished chemotaxis to cAMP |
DBS0350576 | [unk]: mhkC(1-498) | mhkC | abolished protein localization to cell cortex | abolished protein phosphorylation |
DBS0350405 | [unk]: myc: rgaA(K273E/ K282E) | rgaA | aberrant binding |
DBS0350716 | [unk]: pdsA | pdsA | aberrant sorocarp development |
DBS0350259 | [unk]: pikA(1-492(S7A/ S11A/ S109A/ S113A/ S177A/ S181A)) | pikA | increased protein localization to plasma membrane |
DBS0350558 | [unk]: pikI(T262E) | pikI | increased catalytic activity |
DBS0350258 | [unk]: rapA(G12V) | rapA | increased activation of GTPase activity |
DBS0236859 | [unk]: rasD(G12T) | rasD | increased myo-inositol level | decreased gene expression | increased prestalk gene expression | decreased prespore gene expression | development arrests at tipped mound stage | increased protein kinase activation |
DBS0350837 | [unk]: rasD(G12T)/ [rasD]: rapA | rapA | rasD | increased number of mound tips | aberrant culmination | decreased prespore cell differentiation | aberrant gene expression | decreased stalk cell differentiation |
DBS0304636 | [unk]: rasG(Q61L)/ rasG- | rasG | aberrant extracellular cAMP signaling pathway | increased protein modification |
DBS0350597 | [unk]: roco4(1018-1292;F1107L,F1161L) | roco4 | decreased small molecule binding |
DBS0238439 | [unk]: scrA(97-443): GFP | scrA | aberrant cytokinesis | increased vegetative cell size | decreased chemotaxis to cAMP | aberrant cytoskeleton organization |
DBS0351430 | [unk]: tps9(N236A) | tps9 | decreased catalytic activity |
DBS0350056 | [unk]: tubA: GFP/ RNAi]cepG | cepG | tubA | aberrant cytokinesis | aberrant microtubule cytoskeleton organization | aberrant protein localization to nuclear envelope | aberrant centromere complex assembly |
DBS0350913 | [unk]: tubA: GFP/ [RNAi]cepD | cepD | increased number of centrosomes | aberrant mitotic spindle organization | decreased protein localization to microtubule organizing center |
DBS0351237 | [unk]: tubA: GFP/ [RNAi]cepL | cepL | tubA | decreased growth rate | aberrant cytokinesis | aberrant microtubule cytoskeleton organization | aberrant centromere complex assembly |
DBS0351561 | [unk]: vacA: myc: vasP | vacA | vasP | decreased phagocytosis | decreased growth rate | aberrant cytokinesis | increased protein level | aberrant cell morphology |
DBS0350464 | [unk]: vasP(1-197: 221-261: 285-380) | vasP | abolished actin filament polymerization |
DBS0350463 | [unk]: vasP(1-261: 285-380) | vasP | aberrant actin filament organization |
DBS0350465 | [unk]: vasP(1-340: 376-380) | vasP | decreased actin filament polymerization | aberrant actin filament organization |
DBS0237288 | [unk]skp1 | fpaA | fpaB-1 | aberrant fruiting body morphogenesis |
HAD186 | aarA- | aarA | aberrant stalk morphogenesis | aberrant Golgi localization | aberrant epithelium-like organization | decreased prespore gene expression | aberrant centrosome localization | aberrant stalk development | aberrant establishment or maintenance of cell polarity | decreased sporulation |
DBS0349920 | aarA-/ [act15]: GFP-mhcA | aarA | aberrant stalk morphogenesis | aberrant protein localization |
DBS0350143 | abcA10- | abcA10 | aberrant sorocarp development | decreased sporulation |
DBS0350135 | abcA3- | abcA3 | aberrant sorocarp development | aberrant fruiting body morphogenesis | decreased sporulation |
DBS0350138 | abcA4- | abcA4 | aberrant fruiting body morphogenesis |
DBS0350139 | abcA5- | abcA5 | aberrant sorocarp development | decreased sporulation |
DBS0350140 | abcA6- | abcA6 | decreased fruiting body size |
DBS0350141 | abcA7- | abcA7 | aberrant sorocarp development |
DBS0350142 | abcA9- | abcA9 | aberrant fruiting body morphogenesis | decreased sporulation |
DBS0350145 | abcB1- | abcB1 | delayed culmination |
DBS0350146 | abcB4- | abcB4 | decreased sporulation |
DBS0350147 | abcB5- | abcB5 | decreased growth rate | delayed culmination |
DBS0350153 | abcC13- | abcC13 | aberrant sorocarp development | delayed culmination | decreased sporulation |
DBS0350154 | abcC14- | abcC14 | aberrant sorocarp development | decreased fruiting body size | decreased sporulation |
DBS0350148 | abcC2- | abcC2 | aberrant sorocarp development | delayed culmination |
DBS0350149 | abcC3- | abcC3 | delayed culmination |
DBS0350150 | abcC6- | abcC6 | aberrant sorocarp development | delayed culmination |
DBS0350151 | abcC8- | abcC8 | decreased growth rate | increased number of early culminant tips | decreased sporulation |
DBS0350155 | abcD2- | abcD2 | decreased fruiting body size |
DBS0350156 | abcF1- | abcF1 | aberrant sorocarp development | delayed culmination | decreased sporulation |
DBS0350157 | abcF2- | abcF2 | delayed development of tipped mound | decreased sporulation |
DBS0350158 | abcF4- | abcF4 | aberrant sorocarp development | aberrant fruiting body morphogenesis |
DBS0350164 | abcG10- | abcG10 | delayed development of tipped mound | decreased fruiting body size | decreased sporulation |
DBS0350165 | abcG15- | abcG15 | aberrant sorocarp development | decreased sporulation |
DBS0350166 | abcG16- | abcG16 | delayed culmination |
DBS0350167 | abcG17- | abcG17-1 | abcG17-2 | decreased fruiting body size | decreased sporulation |
DBS0350168 | abcG18- | abcG18 | decreased sporulation |
DBS0350169 | abcG19- | abcG19 | delayed aggregation | decreased fruiting body size |
DBS0350160 | abcG2- | abcG2 | delayed development of tipped mound | decreased fruiting body size |
DBS0236539 | abcG2-/ abcG18- | abcG18 | abcG2 | decreased rate of endocytosis | decreased growth rate | abolished vegetative growth |
DBS0236540 | abcG2-/ abcG18-/ rtoA- | abcG18 | abcG2 | rtoA | decreased growth rate | abolished vegetative growth |
DBS0350170 | abcG22- | abcG22 | delayed development of tipped mound | aberrant sorocarp development |
DBS0350171 | abcG24- | abcG24 | decreased sporulation | delayed culmination |
DBS0350161 | abcG5- | abcG5 | delayed culmination |
DBS0350162 | abcG6- | abcG6 | decreased sporulation |
DBS0351078 | abcG6- | abcG6 | delayed aggregation | increased cell-substrate adhesion | decreased cell motility |
DBS0350163 | abcG7- | abcG7 | delayed development of tipped mound | decreased fruiting body size | decreased sporulation |
DBS0350159 | abcH2- | abcH2 | decreased sporulation |
DBS0266687 | abiA- | abiA | abolished protein localization to pseudopodium | decreased protein level | aberrant cytokinesis | decreased growth rate | decreased chemotaxis to folate |
DBS0266688 | abiA- | abiA | abolished protein localization to pseudopodium |
DBS0351531 | abiA-/ AX2 | abiA | abolished protein localization to pseudopodium | decreased migratory slug size | aberrant filopodium formation | aberrant macropinocytosis | decreased cell motility | aberrant pseudopodium formation | decreased fruiting body size |
DBS0350386 | abiA-/ abiA(45-136) | abiA | decreased protein level | aberrant cytokinesis |
DBS0350384 | abiA-/ abiA(45-332) | abiA | aberrant cytokinesis |
DBS0351535 | abiA-/ pirA-/ AX2 | abiA | pirA | aberrant macropinocytosis | decreased cell motility | aberrant cell morphology |
DBS0266689 | abiA-/ scrA- | abiA | scrA | decreased cell motility | decreased vegetative cell size |
LAS53 | abkD- | abkD | aberrant socially cooperative development |
DBS0351065 | abnC- | abnC | delayed aggregation | increased cell-substrate adhesion | decreased cell motility |
DBS0235459 | abpA- | abpA | aberrant hyperosmotic response |
DBS0235456 | abpA-/ abpC- | abpA | abpC | decreased pinocytosis | decreased phagocytosis | decreased growth rate | decreased cell motility | aberrant sorocarp development | aberrant cell-cell adhesion | aberrant hyperosmotic response |
DBS0305672 | abpB- | abpB | increased filopodium formation |
DBS0351087 | abpB-/ abpA- | abpA | abpB | decreased pinocytosis | decreased growth rate | increased cell-cell adhesion | decreased vegetative cell size | aberrant fruiting body morphogenesis | aberrant hyperosmotic response | precocious gene expression | decreased chemotaxis to cAMP |
DBS0351088 | abpB-/ abpC- | abpB | abpC | decreased prespore gene expression | decreased prestalk gene expression | aberrant fruiting body morphogenesis | aberrant hyperosmotic response | decreased chemotaxis to cAMP |
DBS0235425 | abpB-/ fimA- | abpB | fimA | decreased vegetative cell size | decreased fruiting body size | decreased sporulation |
HG1264 | abpC- | abpC | aberrant actin cytoskeleton organization |
DBS0350936 | abpC- | abpC | aberrant cortical actin cytoskeleton organization | decreased phagocytosis | decreased cell motility | decreased chemotaxis to cAMP | aberrant pseudopodium formation | decreased establishment of cell polarity |
DBS0236077 | abpC- | abpC | decreased response to Gram-negative bacterium | aberrant thermotaxis | aberrant cortical actin cytoskeleton organization | decreased cell motility | aberrant phototaxis | decreased establishment of cell polarity | aberrant actin filament polymerization |
HG1270 | abpC- | abpC | aberrant phototaxis |
DBS0237938 | abpC-/ [act15]: GFP: abpC(9-148) | abpC | aberrant phototaxis |
DBS0235426 | abpC-/ [act15]: abpC | abpC | wild type |
DBS0350938 | abpC-/ [act15]: abpC | abpC | wild type |
DBS0237945 | abpC-/ [act15]: abpC(1-348: 449-857): GFP | abpC | aberrant phototaxis | aberrant actin filament organization |
DBS0237946 | abpC-/ [act15]: abpC(1-556: 644-857): GFP | abpC | aberrant phototaxis | aberrant actin filament organization |
DBS0237941 | abpC-/ [act15]: abpC(1-739): GFP | abpC | aberrant phototaxis |
DBS0351553 | abpC-/ [act15]: qkgA(425-1553) | abpC | qkgA-1 | qkgA-2 | aberrant actin filament polymerization |
DBS0237949 | abpC-/ [cotB]: abpC: GFP | abpC | aberrant phototaxis |
DBS0237948 | abpC-/ [ecmA]: abpC: GFP | abpC | wild type |
DBS0235427 | abpD- | abpD | decreased cell-cell adhesion | decreased spore germination | aberrant sorocarp development | delayed development |
DBS0235428 | abpE- | abpE-1 | abpE-2 | increased lateral pseudopodium formation |
DBS0349851 | abpE- | abpE-1 | abpE-2 | aberrant phagosome maturation | precocious phagosome acidification | increased phagocytosis |
DBS0349852 | abpE-/ [act15]: abpE | abpE-1 | abpE-2 | decreased phagocytosis |
DBS0350529 | abpG- | abpG | increased actin filament polymerization | decreased chemotaxis to cAMP | decreased fruiting body size |
DBS0235562 | acaA- | acaA | abolished stream development | abolished gene expression | abolished establishment of cell polarity | decreased gene expression | increased cellular thermotolerance | abolished aggregation | decreased adenylate cyclase activity | decreased cAMP level |
GP6 | acaA- | acaA | increased lateral pseudopodium formation | decreased chemotaxis rate | aberrant actin filament organization | aberrant cell morphology | increased protein kinase activation |
DBS0235429 | acaA- | acaA | decreased gene expression | abolished oscillatory cAMP signaling |
DBS0350720 | acaA-/ [acaA-agg]: acaA: myc | acaA | decreased gene expression | decreased fruiting body size |
DBS0350721 | acaA-/ [acaA-psp]: acaA: myc | acaA | decreased gene expression | decreased mound size | decreased fruiting body size |
DBS0350722 | acaA-/ [acaA-pst]: acaA: myc | acaA | wild type |
DBS0350702 | acaA-/ [act15]: HA: pkaC | acaA | pkaC | wild type | delayed development | decreased cAMP level |
DBS0350725 | acaA-/ [act15]: HA: pkaC/ acrA- | acaA | acrA | pkaC | decreased gene expression | abolished adenylate cyclase activity | development arrests at tipped mound stage |
DBS0350737 | acaA-/ [act15]: acaA | acaA | aberrant slug development |
DBS0350738 | acaA-/ [act15]: acaA(1-390;398-1407) | acaA | abolished aggregation |
DBS0350739 | acaA-/ [act15]: acaA(L394T/ K482N) | acaA | wild type |
DBS0350603 | acaA-/ [act15]: cap: GFP | acaA | cap | development arrests at loose mound stage | increased calcium-dependent cell-cell adhesion | wild type |
DBS0350735 | acaA-/ [act15]: pkaR(G135E/ G261A) | acaA | pkaR | increased cAMP level |
DBS0350736 | acaA-/ [unk]: acaA(F306L/ S498G,K504E,E593V,I649T) | acaA | decreased gene expression | abolished oscillatory cAMP signaling | decreased cAMP level |
DBS0350734 | acaA-/ [unk]: acaA(N333D,G633S) | acaA | abolished adenylate cyclase activity |
DBS0350733 | acaA-/ [unk]: acaA(V427I,S642F) | acaA | abolished activation of adenylate cyclase activity |
DBS0350711 | acaA-/ [unk]: acgA | acaA | acgA | aberrant sorocarp development |
DBS0306125 | acapA- | acapA | wild type |
DBS0350051 | acapA- | acapA | aberrant exocytosis | aberrant filopodium formation | increased defense response to Gram-negative bacterium | aberrant endocytosis | aberrant cytokinesis | aberrant stream morphology | decreased cell motility | delayed development | aberrant lysosome organization |
DBS0350055 | acapA-/ [act15]: acapA(R633Q): GFP | acapA | aberrant filopodium formation | aberrant lysosome organization |
DBS0350054 | acapA-/ [act15]: acapA: GFP | acapA | increased filopodium formation |
DBS0306126 | acapA-/ acapB- | acapA | acapB | decreased sporulation |
DBS0306127 | acapB- | acapB | wild type |
TL177 | acbA- | acbA | decreased response to Gram-negative bacterium | abolished cell migration to prestalk region | abolished spore cell differentiation | decreased sporulation | decreased resistance to cisplatin |
DBS0350194 | acbA-/ [act15]: acbA(Y72A) | acbA | abolished spore cell differentiation |
AK1211 | acbA-/ tagA- | acbA | tagA | increased prestalk B cell differentiation |
DBS0235440 | acgA- | acgA | abolished polyketide metabolic process | decreased spore germination | decreased spore cell differentiation | precocious spore germination | abolished response to biotic stimulus |
DBS0237788 | acgA- | acgA | decreased prespore cell differentiation | decreased prespore gene expression |
DBS0237790 | acgA-/ [acrA]: lacZ | acgA | acrA | aberrant prestalk gene expression |
DG1100 | acrA- | acrA | decreased gene expression | increased stalk length | decreased prespore gene expression | decreased sporulation |
DBS0349939 | acrA- | acrA | aberrant spore coat morphology | decreased stalk width |
DBS0350723 | acrA-/ [act15]: acaA(L394S) | acaA | acrA | precocious spore germination |
DBS0237786 | acrA-/ [act15]: acgA(1-401) | acgA | acrA | decreased prespore gene expression | decreased prespore cell differentiation | decreased sporulation |
DBS0349970 | acrA-/ [act15]: acrA(D1010A) | acrA | decreased adenylate cyclase activity |
DBS0349971 | acrA-/ [act15]: acrA(D1174A) | acrA | increased adenylate cyclase activity |
DBS0349969 | acrA-/ [act15]: acrA(N796D/ D854A/ G856A) | acrA | wild type |
DBS0350724 | acrA-/ [pkaC]: pkaC | acrA | pkaC | decreased spore germination | decreased fruiting body size | precocious development | decreased sporulation |
DBS0351249 | act5-/ [act5]: RFP/ NC4 | act5 | increased chemotaxis to folate | increased fruiting body size | increased growth rate |
DBS0350443 | adcB- | adcB | wild type |
DBS0350444 | adcC- | adcC | wild type |
DBS0351190 | adcC-/ [act15]: adcC(1-485) | adcC | decreased protein localization to plasma membrane |
DBS0351189 | adcC-/ [act15]: adcC(101-654): GFP | adcC | abolished protein localization to plasma membrane |
DBS0350445 | adcC-/ adcB- | adcB | adcC | increased oscillatory cAMP signaling | aberrant endocytosis | delayed aggregation | aberrant regulation of protein kinase activity |
DBS0350538 | adprt1A- | adprt1A | decreased resistance to phleomycin | decreased double-strand break repair via nonhomologous end joining |
DBS0351248 | adprt1A- | adprt1A | decreased gene expression | increased gene expression | decreased ATP level | delayed mitotic cell cycle | decreased growth rate | delayed aggregation | increased prestalk gene expression | decreased mound size | aberrant response to oxidative stress | decreased fruiting body size | increased mitochondrial fission | decreased cAMP level | abolished chemotaxis to cAMP |
DBS0350541 | adprt1A-/ adprt2- | adprt1A | adprt2 | decreased resistance to phleomycin | decreased double-strand break repair via nonhomologous end joining | decreased resistance to cisplatin |
DBS0264268 | adprt1B- | adprt1B | wild type | decreased single-strand break repair | aberrant oscillatory cAMP signaling |
DBS0350539 | adprt2- | adprt2 | decreased single-strand break repair | decreased double-strand break repair | decreased resistance to cisplatin |
DBS0238203 | adrm1- | adrm1-1 | decreased catalytic activity | precocious gene expression | aberrant response to nutrient | precocious development |
DBS0351596 | agnA- | agnA | increased pre-miRNA processing | aberrant production of siRNA involved in RNA interference | increased gene expression | abolished transitive RNA interference |
DBS0351603 | agnA-/ agnB- | agnA | agnB | aberrant production of siRNA involved in RNA interference | increased gene expression |
DBS0351602 | agnB- | agnB | decreased gene expression |
HW420 | agtA- | agtA | development arrests at slug stage |
HW520 | agtA-/ gnt1(1-253/ H104D) | agtA | gnt1 | development arrests at slug stage |
DBS0235457 | ahhA- | ahhA | aberrant late culminant morphology |
DBS0252637 | aip1- | aip1 | decreased pinocytosis | delayed cytokinesis | decreased growth rate | decreased phagocytosis | increased actin filament polymerization | aberrant nucleus morphology | decreased cell motility |
DBS0266759 | alp- | alp | wild type |
DBS0235513 | alrA- | alrA | increased mound size | decreased cell motility | decreased glucose level | decreased protein secretion |
DBS0235473 | alrA-/ [act15]: alrA | alrA | wild type |
DBS0235474 | alxA- | alxA | development arrests at loose mound stage | aberrant standing slug morphology | decreased growth rate |
DBS0235475 | alxA- | alxA | abolished sporulation | aberrant standing slug morphology | aberrant cellular process | decreased gene expression | development arrests at mound stage |
DBS0235488 | alxA-/ [act15]: FLAG: alxA | alxA | delayed development |
DBS0235476 | alxA-/ [act15]: alxA(1-596): myc2 | alxA | aberrant standing slug morphology |
DBS0235477 | alxA-/ [act15]: alxA(1-697): myc2 | alxA | wild type |
DBS0235478 | alxA-/ [act15]: alxA(155-697): myc2 | alxA | aberrant standing slug morphology |
DBS0235479 | alxA-/ [act15]: alxA(293-697): myc2 | alxA | aberrant standing slug morphology |
DBS0235480 | alxA-/ [act15]: alxA(460-794): myc2 | alxA | aberrant standing slug morphology |
DBS0235481 | alxA-/ [act15]: alxA(D310A/ N311A) | alxA | wild type |
DBS0235482 | alxA-/ [act15]: alxA(Q181E/ Q183) | alxA | wild type |
DBS0235483 | alxA-/ [act15]: alxA(S700A/ S704A/ S708A) | alxA | wild type |
DBS0235484 | alxA-/ [act15]: alxA(S700D/ S704D/ S708D) | alxA | wild type |
DBS0235485 | alxA-/ [act15]: alxA(Y315D) | alxA | wild type |
DBS0235486 | alxA-/ [act15]: alxA(Y315F) | alxA | wild type |
DBS0235487 | alxA-/ [act15]: alxA: myc2 | alxA | wild type |
DBS0235489 | alyA- | alyA | increased phagocytosis |
AK1350 | alyL- | alyL | decreased response to Gram-negative bacterium |
DG1114 | amdA- | amdA | decreased spore germination | aberrant sorus color | increased prestalk A cell differentiation |
HM1158 | amdA- | amdA | decreased fruiting body size | decreased sporulation | increased cell differentiation |
DBS0235490 | amiB- | amiB | abolished aggregation |
DBS0235491 | amiB- | amiB | aberrant cell motility | increased gene expression | decreased gene expression | decreased oscillatory cAMP signaling | decreased cGMP-mediated signaling | abolished aggregation | decreased chemotaxis to cAMP |
DBS0235493 | ampA- | ampA | delayed development of tipped mound | delayed prestalk gene expression | precocious prespore gene expression | increased cell-cell adhesion | increased cell-substrate adhesion | aberrant gene expression | delayed development | decreased prestalk cell differentiation |
DBS0349962 | ampA- | ampA | wild type | decreased actin filament polymerization | aberrant chemotaxis to folate | increased cell-substrate adhesion | decreased pseudopodium formation |
DBS0349951 | ampA-/ lmbd2B- | ampA | lmbd2B | aberrant chemotaxis |
DBS0235496 | ampA-/ pspD: lacZ | ampA | aberrant prespore gene expression |
DBS0349963 | ampA-/ sma- | ampA | sma | increased chemotaxis to folate | increased cell-substrate adhesion |
DBS0349953 | ampA/ [ampA]: TAP | ampA | increased protein secretion | development arrests at mound stage |
DBS0235495 | ampA/ [ampA]: ampA | ampA | decreased cell-substrate adhesion | increased pinocytosis | increased actin filament polymerization | aberrant chemotaxis to folate | increased pseudopodium formation |
DBS0349952 | ampA/ [ampA]: ampA/ lmbd2B- | ampA | lmbd2B | aberrant chemotaxis |
BS155 | amtA- | amtA | decreased slug migration | decreased mound size | decreased fruiting body size | increased growth rate | decreased ammonia level |
DBS0267100 | amtA- | amtA | increased number of mounds | increased glucose level | decreased mound size | decreased ammonia level | decreased stalk length | aberrant sporulation | increased intracellular ammonia level |
DBS0267101 | amtA-/ [OE]: amtA | amtA | wild type |
BS165 | amtA-/ amtC- | amtA | amtC | decreased protein localization to nucleus | aberrant slug migration | decreased ammonia level | delayed gene expression |
amtB- | amtB | ||
BS169 | amtB-/ amtA- | amtA | amtB | decreased ammonia level |
BS168 | amtB-/ amtC- | amtB | amtC | decreased ammonia level |
BS154 | amtC- | amtC | abolished protein localization to nucleus | development arrests at slug stage | aberrant gene expression | decreased prestalk gene expression | aberrant fruiting body morphogenesis | decreased ammonia level | delayed culmination |
DBS0235501 | amtC-/ [act15]: cudA | amtC | cudA | delayed culmination |
DBS0235502 | amtC-/ [ecmA]: cudA | amtC | cudA | delayed culmination |
DBS0235503 | amtC-/ [pspA]: cudA | amtC | cudA | development arrests at slug stage |
BS163 | amtC-/ dhkC- | amtC | dhkC | aberrant gene expression |
DBS0236890 | amtC-/ regA- | amtC | regA | precocious sporulation |
DBS0350432 | aoxA- | aoxA | decreased resistance to hydrogen peroxide | aberrant cellular process | aberrant sorocarp development |
DBS0349869 | ap1b1- | ap1b1 | aberrant aggregation | aberrant cell separation during cytokinesis | aberrant contractile vacuole organization | decreased growth rate | aberrant hypotonic response | decreased protein stabilization |
DBS0305197 | ap2a1- | ap2a1-1 | ap2a1-2 | aberrant cell separation during cytokinesis |
DBS0350296 | aph1- | aph1 | aberrant culmination | abolished catalytic activity | decreased prespore cell differentiation |
DBS0351357 | aph1- | aph1 | increased protein modification | decreased phagocytosis | decreased macropinocytosis | aberrant sorocarp development | decreased protein processing in phagocytic vesicle | delayed phagosome acidification |
DBS0350299 | aph1-/ ncstn- | aph1 | ncstn | decreased phagocytosis | decreased prespore cell differentiation |
DBS0350300 | aph1-/ psenA- | aph1 | psenA | aberrant culmination | abolished catalytic activity | decreased prespore cell differentiation |
DBS0350805 | apl- | apl | aberrant response to cisplatin |
DBS0351160 | aplD- | aplD | decreased defense response to Gram-negative bacterium | decreased growth rate |
DBS0351161 | aplP- | aplD | decreased growth rate |
DBS0235505 | apm1- | apm1 | decreased spore germination | aberrant contractile vacuole organization | decreased growth rate | aberrant endosome morphology | aberrant hypotonic response | delayed development | decreased stalk width |
DBS0235506 | apm2- | apm2 | aberrant cell separation during cytokinesis |
DBS0305085 | apm2-/ [dscB]: GFP: vamp7A | apm2 | vamp7A | increased protein localization to plasma membrane |
DBS0235507 | apm3- | apm3 | decreased pinocytosis | increased exocytosis | aberrant endosome morphology | decreased cellular localization | aberrant secretion | aberrant lysosome organization |
DBS0305083 | apm3-/ [dscB]: GFP: vamp7A | apm3 | vamp7A | increased protein localization to plasma membrane |
DBS0235508 | apm4- | apm4 | wild type |
DBS0235509 | aprA- | aprA | aberrant cellular homeostasis | increased mound size | decreased spore germination | increased cell death | aberrant cytokinesis | aberrant vegetative growth | aberrant fruiting body morphogenesis | increased growth rate | abolished chemorepellant activity | decreased sporulation |
DBS0235510 | aprA-/ [act15]: aprA | aprA | decreased growth rate | aberrant fruiting body morphogenesis |
DBS0350009 | aprA-/ [act15]: bzpN: GFP | aprA | bzpN | abolished negative regulation of vegetative growth |
DBS0238124 | aqpA- | aqpA | decreased spore germination | decreased sporulation |
DBS0351484 | aqpB- | aqpB | decreased cell motility |
DBS0351067 | araA- | araA | delayed aggregation | increased cell-substrate adhesion | decreased cell motility | increased protein kinase activation |
HM2245 | arcB(I191L/ D197Y/ K206V/ A213V/ F223L/ P224S/ E232G/ I237T/ H245L/ S250S) | arcB | decreased actin filament polymerization | decreased growth rate | decreased cell motility | decreased chemotaxis rate | decreased pseudopodium formation |
DBS0350886 | areA- | areA | increased autophagy |
DBS0350887 | areB- | areB | increased autophagy |
DBS0235511 | arkA- | arkA | increased gene expression | aberrant fruiting body morphogenesis |
DBS0235512 | arkA-/ [arkA]: arkA: myc2 | arkA | aberrant aggregation |
DBS0350000 | arpB+/ aprB-/ [act15]: myc: arpB(T235A/ T236A) | arpB | wild type |
DBS0349998 | arpB+/ aprB-/ [act15]: myc: arpB(Y200F/ T235A/ T236A) | arpB | decreased actin filament polymerization | delayed aggregation | decreased fruiting body size | decreased establishment of cell polarity | decreased chemotaxis to cAMP | delayed gene expression |
DJK45 | arpB+/ arpB- | arpB | wild type |
DMZ10 | arpB+/ arpB-/ [act15]: myc: arpB | arpB | wild type |
MZ10 | arpB-/ [act15]: myc: arpB | arpB | wild type |
DBS0350191 | arpin- | arpin | increased cell motility |
DBS0350206 | arpin-/ [act15]: GFP: arpin | arpin | wild type |
DBS0350654 | ase1A- | ase1A | aberrant mitotic spindle organization | aberrant cytokinesis | aberrant microtubule cytoskeleton organization |
DBS0350655 | ase1B- | ase1B | aberrant cell morphology |
DBS0235514 | aslA- | aslA-1 | aslA-2 | wild type |
DBS0351219 | ate1- | ate1 | aberrant cell motility | decreased cell-substrate adhesion | decreased vegetative cell size | aberrant actin filament organization |
DBS0236305 | atg1- | atg1 | aberrant macroautophagy | abolished autophagosome organization |
DBS0236304 | atg1- | atg1 | aberrant macroautophagy | aberrant mitochondrion morphology | abolished autophagosome organization |
DBS0350450 | atg1- | atg1 | aberrant autophagy | decreased defense response to Gram-negative bacterium | aberrant defense response to bacterium | aberrant vacuole organization |
DBS0350839 | atg1- | atg1 | decreased catalytic activity | abolished protein localization to autophagosome |
HR131 | atg1- | atg1 | abolished macroautophagy | increased number of autophagosomes | aberrant autophagy | decreased defense response to Gram-negative bacterium | aberrant cellular response to nitrogen starvation | decreased growth rate | abolished spore cell differentiation | aberrant vacuole organization | abolished stalk cell differentiation | abolished aggregation | increased defense response to fungus | decreased defense response to Gram-positive bacterium | aberrant protein localization |
DBS0238085 | atg1-/ [act15]: atg1 | atg1 | wild type |
DBS0238092 | atg1-/ [act15]: atg1(1-628) | atg1 | aberrant cellular response to nitrogen starvation | abolished aggregation |
DBS0238087 | atg1-/ [act15]: atg1(K36A) | atg1 | aberrant cellular response to nitrogen starvation | abolished aggregation |
DBS0238089 | atg1-/ [act15]: atg1(K36A/ 1-628) | atg1 | aberrant cellular response to nitrogen starvation | abolished aggregation |
DBS0238093 | atg1-/ [act15]: atg1(P138S) | atg1 | abolished aggregation |
DBS0266655 | atg1-/ iplA- | atg1 | iplA | decreased necrotic cell death |
DBS0252632 | atg1-/ pcp- | atg1 | pcp | abolished autophagosome organization |
DBS0351613 | atg1-/ tsg101- | atg1 | tsg101 | decreased defense response to Gram-positive bacterium |
DBS0350838 | atg1-/ vmp1- | atg1 | vmp1 | wild type | abolished protein localization to autophagosome |
DBS0350884 | atg101- | atg101 | increased number of tip-organizers | decreased autophagy |
DBS0351232 | atg12- | atg12 | decreased pinocytosis | increased cell death | decreased spore germination | decreased catalytic activity | increased gene expression | increased number of mound tips | increased protein modification | decreased phagocytosis | aberrant phagosome maturation | aberrant fruiting body morphogenesis |
DBS0351233 | atg12-/ tipD- | atg12 | tipD | decreased pinocytosis | increased cell death | decreased spore germination | increased gene expression | increased number of mound tips | increased protein modification | decreased phagocytosis | aberrant phagosome maturation | aberrant fruiting body morphogenesis |
DBS0350883 | atg13- | atg13 | aberrant autophagy | abolished aggregation |
DBS0350885 | atg17- | atg17 | wild type |
HR75 | atg5- | atg5 | increased number of tip-organizers | aberrant macroautophagy | abolished sporulation | aberrant cellular response to nitrogen starvation | abolished aggregation | aberrant protein localization |
DBS0351478 | atg5- | atg5 | abolished sporulation | decreased gene expression | delayed development |
DBS0351582 | atg5- | atg5 | increased cell death | decreased catalytic activity | decreased growth rate | aberrant phagocytosis | increased protein modification | decreased macropinocytosis | aberrant fruiting body morphogenesis | increased growth rate |
DBS0351576 | atg5-/ abpB-/ [dscB]: abpB(D93A/ D95A/ D97A): GFP | abpB | atg5 | aberrant cellular component organization | abolished vegetative growth |
DBS0351583 | atg5-/ atg12- | atg12 | atg5 | increased cell death | decreased catalytic activity | decreased growth rate | decreased phagocytosis | increased protein modification | decreased macropinocytosis | aberrant fruiting body morphogenesis |
DBS0351584 | atg5-/ atg12-/ tipD- | atg12 | atg5 | tipD | increased cell death | decreased catalytic activity | decreased growth rate | aberrant phagocytosis | increased protein modification | decreased macropinocytosis | aberrant fruiting body morphogenesis | increased growth rate |
HR174 | atg6- | atg6A | increased number of tip-organizers | aberrant macroautophagy | decreased defense response to Gram-negative bacterium | aberrant cellular response to nitrogen starvation | decreased spore cell differentiation | decreased defense response to fungus | decreased fruiting body size | decreased stalk length | decreased sporulation |
HR79 | atg7- | atg7 | increased number of tip-organizers | aberrant macroautophagy | abolished sporulation | decreased defense response to Gram-negative bacterium | aberrant cellular response to nitrogen starvation | abolished spore cell differentiation | aberrant protein localization |
DBS0351476 | atg7- | atg7 | aberrant sorus morphology | decreased spore germination | decreased gene expression | decreased prespore cell differentiation | delayed development |
DBS0351477 | atg7-/ [act15]: YFP: atg7(C563A) | atg7 | aberrant sorus morphology | decreased spore germination | delayed development |
DBS0351479 | atg7-/ [act15]: pkaC: YFP | atg7 | pkaC | decreased gene expression | decreased sporulation |
HR141 | atg8- | atg8a | increased number of tip-organizers | aberrant macroautophagy | aberrant spore morphology | aberrant cellular response to nitrogen starvation | decreased spore cell differentiation | aberrant vacuole organization | decreased fruiting body size | decreased defense response to Gram-positive bacterium | decreased sporulation |
DBS0351222 | atg8a- | atg8a | increased cell death | decreased catalytic activity | increased number of mound tips | decreased growth rate | decreased phagocytosis | increased protein modification | delayed development | decreased fruiting body size | aberrant lysosome organization |
DBS0351224 | atg8a-/ atg8b- | atg8a | atg8b | increased cell death | decreased catalytic activity | decreased growth rate | decreased phagocytosis | increased protein modification | aberrant sorocarp development | aberrant lysosome organization |
DBS0351223 | atg8b- | atg8b | precocious development | aberrant lysosome organization |
DBS0305977 | atg9- | atg9 | increased stalk width | decreased pinocytosis | abolished sporulation | aberrant sorus morphology | aberrant autophagy | decreased protein localization to autophagosome | increased number of mound tips | decreased gene expression | decreased phagocytosis | decreased growth rate | abolished catalytic activity | aberrant slug development | aberrant slug migration | aberrant protein modification | aberrant phagosome maturation | decreased prespore cell differentiation | aberrant fruiting body morphogenesis | delayed development | abolished phototaxis |
DBS0305978 | atg9-/ [act15]: GFP: atg9 | atg9 | wild type |
DBS0305979 | atg9-/ [act15]: atg9: GFP | atg9 | wild type |
DBS0350535 | atg9-/ [act15]: cdcD(R154C): RFP | atg9 | cdcD | decreased growth rate | decreased phototaxis |
DBS0351589 | atg9-/ [act15]: cdcD(R154C/ E219K): RFP | atg9 | cdcD | wild type |
DBS0350534 | atg9-/ [act15]: cdcD: RFP | atg9 | cdcD | decreased growth rate | aberrant fruiting body morphogenesis | abolished phototaxis |
DBS0351480 | atg9-/ [act15]: pkaC: YFP | atg9 | pkaC | abolished sporulation |
DBS0350731 | atg9-/ tipD- | atg9 | tipD | decreased pinocytosis | aberrant phagosome maturation | development arrests at tipped mound stage |
DBS0351043 | atp1- | atp1 | decreased defense response to Gram-negative bacterium | decreased gene expression | decreased growth rate | aberrant phototaxis |
DBS0351044 | atp6- | atp6 | decreased defense response to Gram-negative bacterium | decreased gene expression | decreased growth rate | aberrant phototaxis |
HM1591 | axeB- | axeB | aberrant macropinocytosis | increased macropinocytosis | increased phagocytosis |
DBS0351503 | bcas3- | bcas3 | decreased number of autophagosomes | aberrant fruiting body morphogenesis | aberrant phototaxis | decreased sporulation |
DBS0351039 | bzpF- | bzpF | decreased spore germination | decreased gene expression | aberrant fruiting body morphogenesis | aberrant sporulation | decreased sporulation |
DBS0349965 | bzpN- | bzpN | aberrant cytokinesis | abolished negative regulation of vegetative growth | increased growth rate |
DBS0349966 | bzpN-/ [act15]: bzpN: GFP | bzpN | wild type |
DBS0350419 | bzpR- | bzpR | increased stalk width | aberrant sorus morphology | decreased sporulation |
DBS0351486 | c2gapB- | c2gapB | increased cell motility | increased activation of GTPase activity |
DBS0351619 | cadA- | cadA | aberrant vegetative growth |
TL97 | cadA- | cadA | increased number of tip-organizers | decreased calcium-dependent cell-cell adhesion | decreased protein level | increased gene expression | abolished cell migration to prestalk region | increased chemotaxis to cAMP | aberrant cytokinesis | decreased sporulation | delayed culmination | increased prestalk cell differentiation |
DBS0351372 | cadA- | cadA | aberrant defense response to bacterium | decreased growth rate | aberrant response to oxidative stress |
DBS0235561 | cap- | cap | decreased protein level | aberrant pinocytosis | aberrant contractile vacuole organization | aberrant cytokinesis | decreased cell motility | delayed development | aberrant response to osmotic stress |
JB4 | carA- | carA-1 | carA-2 | abolished aggregation |
JS14 | carA- | carA-1 | carA-2 | abolished protein tyrosine phosphorylation | abolished protein localization to nucleus | aberrant phagocytosis | increased cell-substrate adhesion | decreased oscillatory cAMP signaling | decreased cGMP-mediated signaling | aberrant regulation of GTPase activity | abolished aggregation | aberrant regulation of protein kinase activity | abolished chemotaxis to cAMP |
DBS0351266 | carA-/ [act15]: gpbA: YFP | carA-1 | carA-2 | gpbA | abolished aggregation |
DBS0350431 | carA-/ [unk]: carA(261-359;S299A,S302G,S303G,S304G,S308A,S324G,S325A,S331A)(369-392;S383A,S385A): eYFP | carA-1 | carA-2 | aberrant adaptation of signaling pathway | aberrant protein localization to plasma membrane |
RI9 | carA-/ carC- | carA-1 | carA-2 | carC | decreased gene expression | abolished protein localization to plasma membrane |
RI4 | carA-/ carC- | carA-1 | carA-2 | carC | decreased actin filament polymerization | abolished activation of GTPase activity | abolished aggregation | abolished cGMP-mediated signaling | abolished chemotaxis to cAMP |
DBS0350568 | carA-/ carC-/ [act15]: carA(261-359;S299A,S302G,S303G,S304G,S308A,S324G,S325A,S331A)(369-392;S383A,S385A) | carA-1 | carA-2 | carC | abolished stream development | aberrant activation of adenylate cyclase activity | aberrant chemotaxis to cAMP | aberrant oscillatory cAMP signaling | aberrant actin filament polymerization |
DBS0235570 | carB- | carB | development arrests at mound stage |
DBS0350661 | carB- | carB | development arrests at mound stage | abolished development of tipped mound | increased prespore gene expression | decreased prestalk gene expression |
JB6 | carC- | carC | wild type |
DBS0235568 | carD- | carD | decreased migratory slug size | decreased slug migration | increased prespore gene expression | decreased prestalk gene expression | aberrant slug migration | aberrant fruiting body morphogenesis | decreased stalk length | decreased prestalk cell differentiation |
DBS0235573 | carmil- | carmil | decreased pinocytosis | decreased actin filament polymerization | decreased growth rate | decreased mound size |
DBS0266775 | catA- | catA | abolished catalase activity |
X9 | catA- | catA | decreased resistance to hydrogen peroxide | abolished catalase activity |
IR40 | catA- | catA | abolished catalase activity |
IR41 | catA- | catA | abolished catalase activity |
IR29 | catA- | catA | decreased resistance to hydrogen peroxide |
DBS0235574 | catB- | catB | decreased spore resistance to hydrogen peroxide | aberrant gene expression | delayed development | delayed gene expression |
DBS0350249 | cbhA- | cbhA | delayed development |
DBS0350250 | cbhA-/ [cbhA]: cbhA | cbhA | wild type |
DBS0304455 | cblA- | cblA-1 | cblA-2 | aberrant slug development | abolished basal disc formation | aberrant signal transduction |
DBS0351096 | cbpG- | cbpG | decreased cell-substrate adhesion | decreased vegetative cell size |
DBS0235575 | cbpJ- | cbpJ | wild type |
DBS0350238 | ccdc53- | ccdc53 | abolished exocytosis | decreased growth rate | abolished phagosome reneutralization | abolished actin filament polymerization |
DBS0235661 | cdk8- | cdk8 | decreased gene expression | aberrant gene expression | abolished aggregation |
DBS0350435 | cdk8- | cdk8 | decreased spore germination | decreased gene expression | aberrant gene expression | abolished aggregation |
DBS0350436 | cdk8-/ [act15]: myc: cdk8 | cdk8 | wild type |
DBS0350437 | cdk8-/ [act15]: myc: cdk8(D194A) | cdk8 | decreased spore germination | abolished aggregation |
DBS0235578 | cdk8-/ [cdk8]: cdk8 | cdk8 | wild type |
DBS0306226 | cenB- | cenB | increased number of centrosomes | aberrant cell separation during cytokinesis | aberrant nuclear envelope morphology | abolished protein localization to microtubule organizing center | aberrant nucleus morphology | aberrant cytokinesis | decreased microtubule nucleation | aberrant centrosome organization |
DBS0306227 | cenB-/ [act15]: RFP: cenB | cenB | wild type |
DBS0349926 | cepC- | cepC | aberrant mitotic spindle organization | decreased growth rate | aberrant Golgi localization | abolished vegetative growth | aberrant centrosome organization |
DBS0350265 | cepK- | cepK | decreased protein level | decreased protein localization to nuclear envelope | aberrant chemotaxis to cAMP | decreased growth rate | decreased mound size | decreased vegetative cell size | decreased fruiting body size |
DBS0302444 | cfaD- | cfaD | aberrant cellular homeostasis | increased cell death | decreased spore germination | aberrant vegetative growth | aberrant cytokinesis | aberrant fruiting body morphogenesis | increased growth rate | decreased sporulation |
DBS0350010 | cfaD-/ [act15]: bzpN: GFP | bzpN | cfaD | abolished negative regulation of vegetative growth |
DBS0302446 | cfaD-/ [act15]: cfaD | cfaD | wild type |
HO101 | chcA- | chcA | decreased pinocytosis | delayed cell separation during cytokinesis | aberrant cytokinesis | decreased growth rate |
HO103 | chcA- | chcA | abolished sporulation | abolished cytokinesis | abolished gene expression | delayed aggregation | abolished vegetative growth | aberrant fruiting body morphogenesis |
DBS0350090 | chcA-/ [act15]: GFP: ap2a1 | ap2a1-1 | ap2a1-2 | chcA | increased protein localization |
DBS0235588 | chcA-/ [act15]: GFP: mhcA | chcA | mhcA | decreased positive regulation of GTPase activity |
DBS0302455 | chcA-/ [act15]: epnA: GFP | chcA | epnA | aberrant protein localization to clathrin-coated pit |
DBS0350091 | chcA-/ [act15]: gppA: GFP | chcA | gppA | aberrant protein localization to plasma membrane |
DBS0235589 | chcA-/ [cotB]: lacZ | chcA | aberrant prestalk gene expression | aberrant prespore gene expression |
DBS0235590 | chcA-/ [ecmA]: lacZ | chcA | aberrant prestalk gene expression | aberrant prespore gene expression |
DBS0235591 | chcA-/ [ecmB]: lacZ | chcA | aberrant prestalk gene expression | aberrant prespore gene expression |
DBS0235592 | chcA-/ [pspA]: lacZ | chcA | aberrant prestalk gene expression | aberrant prespore gene expression |
DBS0350524 | chdA- | chdA | aberrant culmination | aberrant gene expression | decreased chemotaxis to cAMP |
DBS0350525 | chdB- | chdB | aberrant gene expression | delayed development |
DBS0350526 | chdC- | chdC | decreased growth rate | development arrests at mound stage | aberrant gene expression | aberrant chromatin assembly | decreased chemotaxis to cAMP |
DBS0350528 | chdC-/ [ecmA]: lacZ | chdC | decreased prestalk cell differentiation |
DBS0350527 | chdC-/ [pspA]: lacZ | chdC | decreased prespore cell differentiation |
HM1522 | chlA- | chlA | abolished DIF-1 biosynthesis | aberrant slug development | aberrant fruiting body morphogenesis |
LAS1 | chtB- | chtB | decreased socially cooperative development | increased growth rate |
CCR2 | chtC- | chtC | decreased socially cooperative development | decreased prestalk A cell differentiation |
LAS5 | chtC-REMI | chtC | decreased socially cooperative development |
DBS0305614 | chtC-ins | chtC | decreased socially cooperative development | decreased prestalk A cell differentiation |
DBS0235601 | clc- | clc | abolished cytokinesis | decreased protein localization to plasma membrane | aberrant hypotonic response | abolished vegetative growth | aberrant fruiting body morphogenesis |
DBS0235604 | clc-/ [act15]: GFP-clc(146-194) | clc | abolished cytokinesis | wild type | aberrant fruiting body morphogenesis |
DBS0235605 | clc-/ [act15]: GFP-clc(85-124) | clc | abolished cytokinesis | wild type | aberrant fruiting body morphogenesis |
DBS0235607 | clc-/ [act15]GFP: clc(1-124) | clc | abolished cytokinesis | wild type | aberrant fruiting body morphogenesis |
DBS0350408 | cldA- | cldA | decreased gene expression |
AK1338 | clkB- | clkB | decreased response to Gram-negative bacterium |
DBS0235608 | clmA- | clmA | aberrant contractile vacuole morphology | aberrant hypotonic response |
DBS0350473 | cln3- | cln3 | aberrant aggregation | increased protein secretion | aberrant cell separation during cytokinesis | decreased hypotonic response | aberrant cellular process | increased pinocytosis | delayed aggregation | aberrant cell adhesion | aberrant slug migration | aberrant hyperosmotic response | precocious development | increased growth rate | decreased chemotaxis to cAMP | decreased protein secretion |
DBS0350474 | cln3-/ [act15]: GFP: cln3 | cln3 | wild type |
DBS0351175 | cln5- | cln5 | decreased cell-cell adhesion | aberrant lipid storage | decreased cell-substrate adhesion | decreased chemotaxis to cAMP |
DBS0235609 | cluA- | cluA | decreased mitochondrial fusion | decreased mitochondrial fission | aberrant cytokinesis | aberrant intracellular distribution of mitochondria | aberrant mitochondrion organization |
DBS0349875 | cluA-/ [act15]: cluA | cluA | wild type |
DBS0235612 | cmfB- | cmfB | decreased gene expression | abolished aggregation |
DBS0235613 | cnrB- | cnrB | wild type |
DBS0350308 | cnrF- | cnrF | aberrant contractile vacuole organization | abolished hypotonic response | decreased contractile vacuole size | aberrant regulation of GTPase activity |
DBS0350309 | cnrF-/ [act15]: cnrF: RFP | cnrF | wild type |
DBS0350311 | cnrF-/ cnrF(E623Q/ D659Q) | cnrF | aberrant contractile vacuole organization | abolished hypotonic response | decreased contractile vacuole size | aberrant regulation of GTPase activity |
DBS0350310 | cnrF-/ cnrF(R270A) | cnrF | aberrant contractile vacuole organization | abolished hypotonic response | decreased contractile vacuole size | aberrant regulation of GTPase activity |
DBS0302655 | cnrN- | cnrN | increased oscillatory cAMP signaling | increased number of mounds | decreased spore germination | increased actin filament polymerization | aberrant cytokinesis | aberrant stream morphology | increased growth rate | abolished positive regulation of chemorepellant activity | decreased sporulation |
DBS0302656 | cnrN-/ [act15]: cnrN | cnrN | wild type |
HG1770 | cnxA- | cnxA | decreased calcium ion import | aberrant calcium-mediated signaling |
DBS0235615 | cofB- | cofB | wild type |
DBS0235616 | cofC- | cofC-1 | wild type |
DBS0350522 | comA- | comA | aberrant defense response to bacterium | aberrant phagocytosis | aberrant hyperosmotic response |
DG1016 | comB- | comB | abolished culmination |
DBS0235618 | comC- | comC | aberrant aggregation | aberrant stream morphology |
DBS0235619 | comD- | comD | abolished culmination |
DBS0235620 | comE- | comE | aberrant fruiting body morphogenesis | aberrant sorus color |
DBS0235621 | comF- | comF-1 | comF-2 | abolished aggregation |
DBS0235622 | comG- | comG | increased number of tip-organizers | development arrests at mound stage |
DBS0235623 | comH- | comH | development arrests at mound stage |
HG1570 | corA- | corA | increased myosin II assembly | aberrant cytokinesis | decreased growth rate | decreased cell motility | aberrant cell morphology |
HG1571 | corA- | corA | increased myosin II assembly | aberrant cytokinesis | decreased growth rate | decreased cell motility | aberrant cell morphology |
DBS0351402 | corA- | corA | aberrant actin cytoskeleton organization | aberrant cytokinesis |
HG1569 | corA- | corA | decreased defense response to Gram-negative bacterium | increased myosin II assembly | aberrant cytokinesis | decreased growth rate | decreased phagocytosis | increased actin filament polymerization | decreased cell motility | aberrant cell morphology | decreased defense response to Gram-positive bacterium |
DBS0350370 | corA- | corA | decreased defense response to Gram-negative bacterium | decreased gene expression | aberrant chemotaxis to cAMP | aberrant response to cAMP | decreased phagocytosis | aberrant cellular response to extracellular stimulus | decreased establishment of cell polarity | abolished aggregation |
DBS0351521 | corA-/ [act15]: FLAG: corA(1-432) | corA | abolished aggregation |
DBS0350345 | corA-/ [act15]: GFP: mhkA | corA | mhkA | wild type |
DBS0350346 | corA-/ [act15]: GFP: mhkB | corA | mhkB | wild type |
DBS0350344 | corA-/ [act15]: GFP: mhkC | corA | mhkC | decreased catalytic activity | wild type |
DBS0350343 | corA-/ [act15]: GFP: pakA(797-1197) | corA | pakA | wild type |
DBS0350371 | corA-/ [act15]: corA | corA | wild type |
DBS0350341 | corA-/ [act15]: corA(I118A/ S119A/ P121A): GFP | corA | wild type | aberrant binding | increased myosin II assembly |
DBS0350851 | corA-/ aip1- | aip1 | corA | aberrant endocytosis | aberrant cytokinesis | increased actin filament polymerization | development arrests at mound stage | decreased growth rate | aberrant nucleus morphology | increased vegetative cell size | increased protein level | decreased chemotaxis to cAMP |
DBS0351412 | corA-/ mhcA- | corA | mhcA | aberrant cytokinesis |
DBS0351413 | corA-/ piaA- | corA | piaA | aberrant cytokinesis |
DBS0305825 | corB- | corB | increased lateral pseudopodium formation | aberrant phagocytosis | decreased growth rate | increased cell-substrate adhesion |
DBS0349942 | cosA- | cosA | decreased cell motility | decreased fruiting body size | decreased chemotaxis to cAMP | aberrant actin filament organization | increased pseudopodium formation |
TL55 | cotA- | cotA | decreased spore germination | aberrant spore coat morphology | abolished cellulose binding |
TL53 | cotA-/ cotB- | cotA | cotB | aberrant spore coat morphology |
TL56 | cotA-/ cotB-/ cotC- | cotA | cotB | cotC | decreased spore germination | aberrant spore coat morphology | abolished cellulose binding |
TL57 | cotA-/ cotB-/ cotC- | cotA | cotB | cotC | aberrant spore coat morphology |
TL26 | cotB- | cotB | decreased spore germination | aberrant spore coat morphology | abolished cellulose binding |
TL54 | cotB-/ cotC- | cotB | cotC | aberrant spore coat morphology |
TL52 | cotC- | cotC | aberrant spore coat morphology |
HW07 | cotE(1-235) | cotE | aberrant spore coat morphology |
DBS0351045 | cox3- | cox3 | decreased defense response to Gram-negative bacterium | decreased gene expression | decreased growth rate | aberrant fruiting body morphogenesis | aberrant phototaxis |
DBS0351538 | cpnA-/ AX4 | cpnA | increased contractile vacuole size |
DBS0238297 | cpnA-/ NC4A2 | cpnA | delayed hypotonic response | increased migratory slug size | decreased post-lysosomal vacuole size | increased mound size | aberrant thermotaxis | increased contractile vacuole size | increased exocytosis | decreased growth rate | aberrant cytokinesis | aberrant stalk cell differentiation | development arrests at slug stage | decreased number of post-lysosomal vacuoles | aberrant fruiting body morphogenesis | delayed development | abolished phototaxis |
DBS0238320 | cpnA-/ [act15]: GFP: cpnA | cpnA | delayed hypotonic response | decreased culmination | delayed development |
DBS0350869 | crlA-/ AX2 | crlA | wild type |
DBS0235627 | crlA-/ KAX3 | crlA | delayed development of tipped mound | abolished polyketide metabolic process | increased mound size | decreased spore germination | decreased spore cell differentiation | decreased cell migration to prestalk region | increased growth rate |
DBS0235628 | crlA-/ [crlA]: crlA | crlA | increased mound size |
DBS0235629 | crlB- | crlB | wild type |
DBS0235630 | crlC- | crlC | wild type |
HG1768 | crtA- | crtA | decreased calcium ion import | aberrant calcium-mediated signaling |
HG1772 | crtA-/ cnxA- | cnxA | crtA | decreased calcium ion import | decreased growth rate | delayed response to cAMP | decreased phagocytosis | aberrant calcium-mediated signaling |
DBS0235633 | crtf- | crtf | abolished sporulation | decreased gene expression | abolished aggregation |
DBS0351557 | cryS- | cryS | decreased pinocytosis | decreased culmination | decreased phagocytosis | aberrant cytokinesis | decreased growth rate |
AX2-T10 | csaA- | csaA | decreased cell-cell adhesion | decreased culmination | abolished protein localization to cell-cell contact zone | delayed aggregation | increased cell-substrate adhesion | decreased sporulation |
TL73 | csaA-/ csbA-/ csbC-/ csbC- | csaA | csbA | csbB | csbC | increased stalk width | aberrant late culminant morphology |
TL122 | csaA-/ tgrC1- | csaA | tgrC1 | abolished calcium-independent cell-cell adhesion |
TL72 | csbA-/ csbB-/ csbC- | csbA | csbB | csbC | increased resistance to cisplatin | aberrant cytokinesis | aberrant late culminant morphology |
WTC127 | cshA- | cshA | development arrests at loose mound stage | decreased phagocytosis | decreased growth rate | delayed aggregation |
DBS0235634 | csn5-KD | csn5 | decreased growth rate |
DBS0235624 | ctnA- | ctnA | increased cGMP-mediated signaling | aberrant cellular metabolic process | increased glucose level | decreased protein level | increased mound size | decreased catalytic activity | increased guanylyl cyclase activity | decreased actin filament polymerization | decreased oscillatory cAMP signaling | increased cell-cell adhesion | increased protein level | increased cell motility | decreased myosin II assembly |
DBS0235636 | ctnB- | ctnB | increased number of mounds | decreased gene expression | decreased fruiting body size |
DBS0304927 | ctnnA- | ctnnA | wild type |
DBS0304928 | ctnnA-/ mhcA- | ctnnA | mhcA | aberrant cytokinesis |
DG1071 | ctr9- | ctr9 | aberrant fruiting body morphogenesis |
DG1058 | ctrA- | ctrA | decreased fruiting body size |
DBS0350915 | ctsD- | ctsD | aberrant protein modification |
DBS0235598 | ctxA- | ctxA | aberrant cytokinesis | decreased cell motility | aberrant cell morphology |
HS1151 | ctxA- | ctxA | aberrant cytokinesis | decreased growth rate | aberrant stream morphology | aberrant cellular response to stress |
DBS0237568 | ctxA-/ [RNAi]enlA | ctxA | enlA | wild type |
DBS0349922 | ctxA-/ [act15]: GFP-mhcA | ctxA | aberrant protein localization to basolateral plasma membrane | aberrant stalk morphogenesis | aberrant development of tipped mound |
DBS0237536 | ctxA-/ [act15]: enlA(92-497) | ctxA | enlA | wild type |
DBS0235599 | ctxA-/ ctxB- | ctxA | ctxB | abolished stream development | aberrant cellular response to fluid shear stress | abolished adenylate cyclase activity | increased lateral pseudopodium formation | aberrant cytokinesis | development arrests at mound stage | aberrant chemotaxis to cAMP | decreased cell motility | aberrant regulation of GTPase activity | aberrant cell morphology | abolished aggregation | aberrant regulation of protein kinase activity | increased bleb assembly |
DBS0350293 | ctxA-/ ctxB-/ [act15]: GFP: arcA | arcA | ctxA | ctxB | aberrant protein localization to cell cortex |
DBS0349972 | ctxA-/ ctxB-/ [act15]: acaA: YFP | acaA | ctxA | ctxB | aberrant fruiting body morphogenesis |
DBS0349973 | ctxA-/ ctxB-/ [act15]: carA: YFP | carA-1 | carA-2 | ctxA | ctxB | abolished stream development | abolished adenylate cyclase activity | development arrests at tight mound stage |
DBS0235600 | ctxB- | ctxB | aberrant cytokinesis | aberrant stream morphology | aberrant cell morphology |
DBS0350404 | ctxC- | ctxC | increased pinocytosis | decreased oscillatory cAMP signaling | aberrant stream morphology | decreased chemotaxis to cAMP | increased growth rate | increased phagocytosis |
DBS0235639 | cudA- | cudA | abolished sporulation | decreased gene expression | development arrests at slug stage | decreased prespore gene expression | abolished stalk cell differentiation |
DBS0238017 | cudA- | cudA | abolished gene expression |
DBS0235640 | culA- | culA | increased number of tip-organizers | development arrests at tipped mound stage |
DBS0235641 | culA-/ [cotC]: culA | culA | increased sorus size | decreased stalk length | decreased sporulation |
DBS0235642 | culA-/ [ecmA]: culA | culA | increased sorus size | decreased stalk length |
DBS0235643 | culA-/ [pkaC]pkaC | culA | pkaC | wild type |
DBS0266745 | culB- | culB | increased number of mound tips | precocious prestalk gene expression | aberrant slug development | decreased fruiting body size | decreased sporulation |
DBS0266761 | culB-/ [act15]: pkaC | culB | pkaC | abolished sporulation | precocious prestalk gene expression | abolished aggregation | abolished prespore gene expression |
DBS0266760 | culB-/ pkaR- | culB | pkaR | abolished sporulation | precocious prestalk gene expression | abolished aggregation | abolished prespore gene expression |
DBS0235651 | cybA- | cybA | abolished sporulation | aberrant sorocarp development |
DBS0350641 | cynA- | cynA | aberrant cell motility | decreased actin filament polymerization | aberrant chemotaxis to cAMP | delayed aggregation | aberrant cell morphology |
DBS0351047 | cytB- | cytB | decreased defense response to Gram-negative bacterium | decreased gene expression | development arrests at mound stage | decreased growth rate | aberrant phototaxis |
AK108 | dagA- | dagA | abolished gene expression | decreased gene expression | abolished activation of adenylate cyclase activity | abolished aggregation | decreased chemotaxis to cAMP |
BW4 | dagA- | dagA | abolished positive regulation of chemorepellant activity |
DBS0235652 | dagA-/ [act15]: dagA | dagA | wild type |
DBS0235560 | dagA-/ acaA(L394S) | acaA | dagA | wild type |
DBS0235653 | darA- | darA | decreased mound size | abolished aggregation |
DBS0350531 | dclre1- | dclre1 | decreased resistance to bleomycin | decreased double-strand break repair via nonhomologous end joining | aberrant double-strand break repair via homologous recombination |
DBS0236307 | dcsA- | dcsA | abolished cellulose biosynthesis |
DG1099 | dcsA- | dcsA | abolished stalk development | abolished sporulation | aberrant spore coat morphology | abolished cellulose biosynthesis | abolished stalk cell differentiation |
DG1128 | dcsA- | dcsA | abolished stalk development | abolished sporulation | aberrant spore coat morphology | abolished cellulose biosynthesis |
TL127 | dcsA- | dcsA | abolished stalk development | abolished sporulation | aberrant spore coat morphology | abolished cellulose biosynthesis | abolished stalk cell differentiation | aberrant stalk development |
TL128 | dcsA-/ [act15]: dcsA | dcsA | wild type |
DBS0351195 | dct- | dct | aberrant chemotaxis to cAMP | increased activation of GTPase activity |
DBS0349967 | dcx-/ lis1(D327H) | dcx | lis1 | abolished aggregation |
DBS0349804 | detA- | detA | increased mound size | decreased growth rate | delayed development |
DBS0349807 | detA-/ [act6]: GFP: detA | detA | wild type |
DBS0349816 | detA-/ [act6]: GFP: detA/ [act6]: 3xHA: culD | culD | detA | increased gene expression |
DBS0349817 | detA-/ [act6]: GFP: detA/ [act6]: 3xHA: repE | detA | repE | increased gene expression |
DBS0349813 | detA-/ [cotB]: GFP | detA | decreased prespore cell differentiation |
DBS0349811 | detA-/ [ecm0]: lacZ | detA | aberrant prestalk O cell differentiation |
DBS0349812 | detA-/ [ecmA0]: GFP | detA | increased prestalk cell differentiation |
DBS0349808 | detA-/ [ecmA0]: lacZ | detA | increased prestalk cell differentiation |
DBS0349809 | detA-/ [ecmA]: lacZ | detA | increased prestalk A cell differentiation |
DBS0349810 | detA-/ [ecmB]: lacZ | detA | delayed development |
DBS0350392 | dgat1- | dgat1 | aberrant cellular metabolic process | abolished lipid droplet formation | increased sporulation |
DBS0350393 | dgat1-/ dgat2- | dgat1 | dgat2 | abolished lipid droplet formation | decreased growth rate | increased sporulation | aberrant endoplasmic reticulum membrane organization |
DBS0350394 | dgat1-/ dgat2-/ [act15]: GFP: dgat2 | dgat1 | dgat2 | wild type |
DBS0349911 | dgcA- | dgcA | decreased gene expression | development arrests at slug stage | abolished stalk cell differentiation |
DBS0349917 | dgcA-/ [act15]: dgcA(1-124): YFP | dgcA | development arrests at slug stage |
DBS0349918 | dgcA-/ [act15]: dgcA(1-273): YFP | dgcA | development arrests at slug stage |
DBS0349914 | dgcA-/ [act15]: dgcA(125-521): YFP | dgcA | wild type |
DBS0349915 | dgcA-/ [act15]: dgcA(274-521): YFP | dgcA | wild type |
DBS0349916 | dgcA-/ [act15]: dgcA(350-521): YFP | dgcA | development arrests at slug stage |
DBS0349913 | dgcA-/ [act15]: dgcA-Ppal: YFP | dgcA | wild type |
DBS0349912 | dgcA-/ [act15]: dgcA: YFP | dgcA | wild type |
DBS0235695 | dgkA- | dgkA | decreased spore germination | increased myosin II assembly | aberrant sorocarp development | decreased chemotaxis rate |
DBS0351179 | dgkA- | dgkA | aberrant cellular metabolic process | increased resistance to valproic acid | aberrant response to lithium |
AK299 | dhkA- | dhkA | aberrant stalk morphogenesis | increased prestalk gene expression | aberrant gene expression | aberrant fruiting body morphogenesis | increased sporulation | abolished response to biotic stimulus | decreased sporulation |
DBS0350665 | dhkA-/ [act15]: dhkA(D2076N) | dhkA | decreased sporulation |
DBS0350664 | dhkA-/ [act15]: dhkA(H1396Q) | dhkA | decreased sporulation |
DBS0350666 | dhkA-/ [act15]: dhkA(H2396Q)/ [act15]: dhkA(D2076N) | dhkA | wild type |
DBS0235703 | dhkA-/ [pkaC]: pkaC | dhkA | pkaC | aberrant stalk morphogenesis |
TL134 | dhkA-/ dhkB- | dhkA | dhkB | abolished sporulation | increased stalk length | decreased stalk width |
HR49 | dhkA-/ fbxA- | dhkA | fbxA | aberrant fruiting body morphogenesis | decreased sporulation | decreased cAMP level |
HR51 | dhkA-/ fbxA- | dhkA | fbxA | aberrant fruiting body morphogenesis | decreased sporulation |
HR50 | dhkA-/ fbxA- | dhkA | fbxA | abolished culmination | decreased sporulation |
DBS0350663 | dhkA-/ pkaR- | dhkA | pkaR | decreased sporulation |
DBS0350662 | dhkA-/ regA- | dhkA | regA | decreased sporulation |
DBS0235704 | dhkB- | dhkB | precocious spore germination | decreased cAMP level | aberrant sorus color |
TL135 | dhkC- | dhkC | precocious culmination | decreased spore germination | precocious aggregation | precocious development | precocious gene expression |
DBS0350855 | dhkC- | dhkC | aberrant chemotaxis to cAMP |
DBS0350379 | dhkD- | dhkD | abolished stream development | aberrant slug development | aberrant sorocarp development | precocious gene expression | aberrant late culminant morphology |
DBS0350381 | dhkD-/ [ecmAO]: lacZ | dhkD | aberrant prestalk cell differentiation |
DBS0350382 | dhkD-/ [ecmB]: lacZ | dhkD | aberrant prestalk cell differentiation |
DBS0350383 | dhkD-/ [pspA]: lacZ | dhkD | aberrant prespore cell differentiation |
LAS99 | dhkE- | dhkE | decreased socially cooperative development |
DBS0351297 | dhkI- | dhkI-1 | dhkI-2 | aberrant chemotaxis to cAMP | delayed aggregation |
DBS0235710 | dhkK- | dhkK | aberrant slug migration | delayed culmination | delayed gene expression |
DBS0235712 | dhkK-/ [act15]: dhkK(D1125N) | dhkK | aberrant fruiting body morphogenesis |
DBS0235714 | dhkK-/ regA- | dhkK | regA | precocious development |
DBS0348046 | dhkM- | dhkM | abolished autophagosome organization | aberrant autophagic cell death |
DBS0348047 | dhkM- | dhkM | abolished autophagosome organization | abolished actin filament depolymerization | abolished cellulose biosynthesis | abolished autophagic cell death |
DBS0350173 | dhkM- | dhkM | decreased autophagic vacuole organization | delayed development |
DBS0235719 | dia1-/ [act6]: trap1 | dia1 | trap1 | aberrant aggregation | decreased fruiting body size |
DBS0235895 | dimA- | dimA | increased standing slug length | increased migratory slug size | abolished prestalk cell differentiation | decreased standing slug width | aberrant fruiting body morphogenesis | increased prespore cell differentiation | decreased prestalk O cell differentiation |
DBS0235899 | dimA-/ dimB- | dimA | dimB | increased migratory slug size | increased standing slug length | aberrant chemotaxis to cAMP | decreased standing slug width |
DBS0235901 | dimB- | dimB | decreased prestalk B cell differentiation | abolished response to DIF-1 | increased gene expression | aberrant prespore gene expression | aberrant chemotaxis to cAMP |
DBS0235903 | dimB-/ [act15]: dimA: GFP | dimA | dimB | abolished protein localization to nucleus |
DBS0235904 | dimB-/ [act15]: dimB: GFP | dimB | wild type |
DBS0349992 | dimB-/ [btg]: lacZ | btg | dimB | increased gene expression |
DBS0235902 | dimB-/ [cotB]: lacZ | dimB | increased prespore cell differentiation |
DBS0350573 | dimB-/ [dimB]: dimB(S590A) | dimB | wild type |
DBS0235906 | dimB-/ [ecmAO]: lacZ | dimB | decreased prestalk O cell differentiation |
DBS0349974 | dimB-/ [ecmB]: lacZ | dimB | abolished prestalk gene expression |
DBS0235907 | dimB-/ [ecmO]: lacZ | dimB | aberrant prestalk cell differentiation |
DBS0350495 | dio3- | dio3 | decreased cell-cell adhesion | aberrant aggregation | decreased gene expression | decreased growth rate | decreased prespore cell differentiation | decreased chemotaxis to folate | increased prestalk cell differentiation | decreased cAMP level | decreased phototaxis |
DBS0350496 | dio3-/ [act15]: GFP: dio3 | dio3 | wild type |
DBS0304919 | dlpA- | dlpA | aberrant cell separation during cytokinesis | aberrant cytokinesis | decreased growth rate | increased actin filament depolymerization | increased vegetative cell size | decreased protein localization | abolished protein localization to cleavage furrow | aberrant actin filament organization |
DBS0351395 | dlpA-/ dlpB- | dlpA | dlpB | aberrant cytokinesis |
DBS0304920 | dlpB- | dlpB | aberrant cell separation during cytokinesis | aberrant cytokinesis | decreased growth rate | increased vegetative cell size | abolished protein localization to cleavage furrow |
DBS0304921 | dlpC- | dlpC | aberrant cytokinesis |
DBS0235913 | dmpA- | dmpA | aberrant stream morphology | aberrant fruiting body morphogenesis | delayed development | decreased stalk cell differentiation | decreased sporulation | aberrant sorus color |
HM1030 | dmtA- | dmtA | delayed development of tipped mound | abolished DIF-1 biosynthesis | decreased outer basal disc size | wild type | abolished prestalk O cell differentiation | decreased standing slug width | decreased lower cup size | decreased prestalk gene expression | aberrant vacuole organization | aberrant fruiting body morphogenesis | delayed development | decreased prestalk O cell differentiation | decreased prestalk cell differentiation |
DBS0350410 | dmtA-/ [act15]: dmtA | dmtA | wild type |
DBS0349975 | dmtA-/ [dimB]: dimB | dimB | dmtA | decreased prestalk B cell differentiation |
HM1196 | dmtA-/ stlA- | dmtA | stlB | decreased outer basal disc size | decreased prestalk O cell differentiation |
DBS0235914 | dnapkcs- | dnapkcs | decreased resistance to bleomycin | decreased double-strand break repair via nonhomologous end joining |
DBS0266875 | dnapkcs-/ GFP: pcna | dnapkcs | pcna | aberrant response to bleomycin |
DBS0350561 | dnapkcs-/ adprt2- | adprt2 | dnapkcs | decreased resistance to phleomycin | decreased resistance to cisplatin |
DBS0351060 | dnapkcs-/ exo1- | dnapkcs | exo1 | decreased resistance to phleomycin |
DBS0235915 | dng1- | dng1 | decreased growth rate | delayed aggregation |
DBS0235917 | dnmA- | dnmA | decreased DNA methylation on cytosine |
DBS0235916 | dnmA- | dnmA | decreased DNA methylation on cytosine | aberrant late culminant morphology | aberrant sorus color | decreased sporulation |
DBS0350457 | docA- | docA | decreased chemotaxis to cAMP |
DG2015 | docA- | docA | development arrests at mound stage |
LAS32 | docA- | docA | decreased socially cooperative development |
DBS0350458 | docD- | docD | decreased cell motility | decreased chemotaxis to cAMP |
DBS0350459 | docD-/ docA- | docA | docD | aberrant fruiting body morphogenesis | delayed development | decreased chemotaxis to cAMP |
DBS0235920 | dokA- | dokA | aberrant hyperosmotic response | aberrant sorus color | decreased sporulation |
DBS0349789 | dotA- | dotA | aberrant response to UV | decreased growth rate | decreased spore size | delayed development | abolished histone H3-K79 methylation |
HAD172 | dpoA- | dpoA | increased gene expression | aberrant sorocarp development |
HAD200 | dpoA- | dpoA | aberrant sorocarp development |
HAD201 | dpoA- | dpoA | aberrant sorocarp development |
HAD202 | dpoA- | dpoA | aberrant sorocarp development |
HAD203 | dpoA- | dpoA | aberrant sorocarp development |
HAD205 | dpoA-/ gskA- | dpoA | gskA | aberrant sorocarp development |
HM1467 | drcA- | drcA | abolished catalytic activity |
DBS0238474 | drkC- | drkC | decreased phagocytosis | decreased phagolysosome formation |
DBS0238511 | drkC-/ [act15]: drkC(1-497): YFP | drkC | decreased phagocytosis |
DBS0238513 | drkC-/ [act15]: drkC(K518R): YFP | drkC | decreased phagocytosis |
DBS0238475 | drkC-/ [act15]: drkC: YFP | drkC | wild type |
DBS0235922 | drnA- | drnA-1 | decreased gene expression |
DBS0350174 | drnB- | drnB | abolished pre-miRNA processing |
DBS0350218 | drnB-/ [act15]: pre-miRNA | drnB | abolished pre-miRNA processing |
DBS0350210 | drnB-/ [act6]: lacZ/ [RNAi]lacZ | drnB | abolished production of siRNA involved in RNA interference | abolished transitive RNA interference |
DBS0235924 | dscA- | dscA-1 | dscA-2 | aberrant cell morphology |
DBS0350775 | dscA- | dcsA | decreased cell motility |
DBS0302609 | dsgg(1-571: 581-733) | dsgg | aberrant contractile vacuole organization |
DBS0302608 | dsgg(1-571: 581-733)/ dsgg- | dsgg | aberrant contractile vacuole organization | aberrant cellular localization |
DBS0302597 | dsgg- | dsgg | aberrant contractile vacuole organization | aberrant hypotonic response |
DBS0302603 | dsgg-/ GFP: dsgg | dsgg | wild type |
DBS0302602 | dsgg-/ OE]: dsgg(Delta-Fbox) | dsgg | wild type |
DBS0302606 | dsgg-/ [OE]: GFP: lvsD | dsgg | lvsD | wild type |
DBS0302599 | dsgg-/ [OE]: dsgg | dsgg | wild type |
DBS0302601 | dsgg-/ [OE]: dsgg(Q551A) | dsgg | aberrant contractile vacuole organization |
DBS0302600 | dsgg-/ [OE]: dsggR515A) | dsgg | aberrant contractile vacuole organization |
DBS0302607 | dsgg-/ [OE]: lvsA | dsgg | lvsA | aberrant contractile vacuole organization |
DBS0302611 | dsgg-/ [OE]: phgA | dsgg | phgA | aberrant contractile vacuole organization |
DBS0302678 | dsgg-/ [OE]: rab8A | dsgg | rab8A | aberrant contractile vacuole organization |
DBS0302604 | dsgg-/ lvsA- | dsgg | lvsA | wild type |
DBS0302605 | dsgg-/ lvsD- | dsgg | lvsD | aberrant contractile vacuole organization |
DBS0351070 | dspA- | dspA | delayed aggregation | increased cell-substrate adhesion | decreased cell motility | increased protein kinase activation |
DBS0235925 | dstA- | dstA | abolished gene expression | increased gene expression | aberrant prestalk gene expression | abolished cell migration to prestalk region | decreased gene expression | delayed aggregation | decreased prestalk gene expression | decreased cell motility | abolished stalk cell differentiation | aberrant fruiting body morphogenesis |
DBS0235926 | dstA- | dstA | aberrant prestalk gene expression | abolished cell migration to prestalk region | delayed aggregation | decreased cell motility | abolished stalk cell differentiation | aberrant fruiting body morphogenesis |
DBS0238237 | dstA-/ GFP: dstA(237-707): ORF+ | dstA | abolished culmination | decreased stalk length |
DBS0238236 | dstA-/ GFP: dstA(237-707): ORF+/ [OE]dutA(751-1322) | dstA | dutA | decreased stalk length |
DBS0252824 | dstA-/ GFP: dstA(237-707): ORF+/ [act15]: 2C | 2C | dstA | aberrant fruiting body morphogenesis |
DBS0252823 | dstA-/ GFP: dstA(237-707): ORF+/ [act15]: 7E | 7E | dstA | hssB | wild type |
DBS0252826 | dstA-/ GFP: dstA(237-707): ORF+/ [act15]: DDB_G0276165 | DDB_G0276165 | dstA | aberrant fruiting body morphogenesis |
DBS0252825 | dstA-/ GFP: dstA(237-707): ORF+/ [act15]: DDB_G0282325 | DDB_G0282325 | dstA | aberrant fruiting body morphogenesis |
DBS0252816 | dstA-/ GFP: dstA(237-707): ORF+/ [act15]: hssA | dstA | hssA | wild type |
DBS0252822 | dstA-/ GFP: dstA(237-707): ORF+/ [act15]: hssB | dstA | hssB | wild type |
DBS0235928 | dstA-/ [act15]: dstA | dstA | wild type |
DBS0235929 | dstA-/ [cprB]: dstA | dstA | wild type |
DBS0235930 | dstA-/ [ecmAO]: dstA | dstA | wild type |
DBS0235927 | dstA-/ dstB- | dstA | dstB | wild type |
DBS0235931 | dstB- | dstB | decreased gene expression | increased gene expression | decreased growth rate |
DBS0235933 | dstB-/ [act15]: dstB | dstB | wild type |
DBS0235934 | dstB-/ [act15]: dstB(L1025R) | dstB | wild type |
DBS0235935 | dstB-/ [act15]: dstB(Y1143F) | dstB | wild type |
DBS0235932 | dstB-/ dstC- | dstB | dstC | wild type |
DBS0238125 | dstC- | dstC | abolished gene expression | aberrant response to cation stress | aberrant response to osmotic stress |
DBS0350425 | dstC- | dstC | aberrant protein phosphorylation |
DBS0235937 | dtfA- | dtfA | delayed development of tipped mound | decreased cell-cell adhesion | aberrant cytokinesis | aberrant cell migration to prestalk region | aberrant fruiting body morphogenesis |
DBS0350500 | dupA- | dupA | increased defense response to Gram-negative bacterium | abolished aggregation |
DBS0350502 | dupA- | dupA | increased defense response to Gram-negative bacterium |
DBS0238234 | dutA- | dutA | wild type |
DBS0235939 | dwwA- | dwwA | aberrant cytokinesis | aberrant actin filament organization | aberrant cell morphology |
DBS0350411 | dydA- | dydA | increased myosin II assembly | increased actin filament polymerization | increased protein localization to plasma membrane | decreased chemotaxis to cAMP |
DBS0350414 | dydA-/ dydA(1-278: 501-1211) | dydA | decreased protein localization to cell cortex | increased myosin II assembly | increased actin filament polymerization | aberrant chemotaxis to cAMP |
DBS0350415 | dydA-/ dydA(1-586: 703-1211) | dydA | decreased protein localization to cell cortex | decreased chemotaxis to cAMP |
DBS0350060 | dymA- | dymA | decreased protein localization to cleavage furrow | aberrant cell separation during cytokinesis | decreased growth rate | increased vegetative cell size | aberrant actin filament organization |
DBS0347874 | dymA- | dymA | decreased pinocytosis | aberrant cell separation during cytokinesis | aberrant mitochondrion morphology | decreased phagolysosome size | increased basal disc size | decreased growth rate | aberrant nucleus morphology | increased vegetative cell size | aberrant endosome morphology | aberrant phagosome maturation | delayed development | aberrant stalk development | aberrant fruiting body morphogenesis | decreased establishment of cell polarity | aberrant pseudopodium formation | abolished phagosome acidification | increased phagocytosis | aberrant intracellular distribution of mitochondria |
DBS0349839 | dymA-/ [dymA]: dymA | dymA | wild type |
DBS0350803 | dymA-/ ehd- | dymA | ehd | aberrant phagosome maturation | decreased protein processing in phagocytic vesicle |
DBS0347875 | dymB- | dymB | decreased growth rate | aberrant hypotonic response | increased cell-cell adhesion | increased cell-substrate adhesion | decreased vegetative cell size | decreased catalase activity | aberrant actin filament organization | increased growth rate | increased phagocytosis |
DBS0235940 | eb1- | eb1 | aberrant mitosis | aberrant cytokinesis | aberrant protein localization |
HJW117 | ecmA- | ecmA | increased standing slug length | decreased standing slug width | decreased slime trail |
HJW01 | ecmB- | ecmB | wild type |
HJW03 | ecmB- | ecmB | wild type |
DBS0235944 | ecmF- | ecmF | wild type |
DBS0350904 | efbA- | efbA | aberrant cytokinesis | delayed development |
DBS0235945 | egeA- | egeA | decreased activation of adenylate cyclase activity | decreased gene expression | abolished aggregation |
DBS0350520 | egeA-/ [unk]: YFP: carA | carA-1 | carA-2 | egeA | development arrests at mound stage |
DBS0350521 | egeA-/ [unk]: pkaC | egeA | pkaC | decreased gene expression | abolished aggregation |
DBS0235946 | egeB- | egeB | development arrests at mound stage |
DBS0350802 | ehd- | ehd | aberrant endosome morphology | aberrant phagosome maturation | decreased protein processing in phagocytic vesicle |
DBS0350804 | ehd-/ [act15]: dymA: GFP | dymA | ehd | aberrant phagosome maturation | decreased protein processing in phagocytic vesicle |
DBS0351166 | ei24- | ei24 | aberrant aggregation | decreased spore germination | increased gene expression | decreased gene expression | decreased growth rate | aberrant cell cycle | delayed development | decreased chemotaxis to cAMP | decreased fruiting body size | decreased cAMP level | decreased sporulation |
DBS0302590 | elmoA- | elmoA | increased protein localization to pseudopodium | decreased culmination | abolished establishment of cell polarity | increased actin filament polymerization | decreased cell motility | delayed development | increased pseudopodium formation | increased phagocytosis |
DBS0302598 | elmoA-/ [act15]: elmoA(1-903/ 959-977): GFP | elmoA | decreased cell motility | increased phagocytosis |
DBS0302591 | elmoA-/ [act15]: elmoA: GFP | elmoA | wild type |
DBS0350065 | elmoE- | elmoE | decreased culmination | decreased actin filament polymerization at leading edge | decreased chemotaxis to cAMP |
DBS0351604 | elp3- | elp3 | decreased protein level |
DBS0302448 | epnA- | epnA | aberrant spore morphology | decreased spore germination | abolished protein localization to cell cortex | aberrant cytokinesis | abolished protein localization to plasma membrane | aberrant actin cytoskeleton organization | abolished protein phosphorylation |
DBS0302457 | epnA-/ [act15]: GFP: epnA(253-677) | epnA | aberrant spore morphology | abolished protein localization to plasma membrane | abolished protein localization to clathrin-coated pit |
DBS0302456 | epnA-/ [act15]: epnA(1-133): GFP | epnA | aberrant localization to coated pits |
DBS0302474 | epnA-/ [act15]: epnA(R65A/ K78A): GFP | epnA | aberrant spore morphology | abolished protein localization to plasma membrane | abolished phosphatidylinositol-4,5-bisphosphate binding | abolished protein localization to clathrin-coated pit | abolished protein phosphorylation |
DBS0302475 | epnA-/ [act15]: epnA(T107A): GFP | epnA | aberrant spore morphology | abolished protein localization to plasma membrane |
DBS0302454 | epnA-/ [act15]: epnA: GFP | epnA | wild type |
DBS0235947 | eppA- | eppA | decreased growth rate | delayed development | decreased chemotaxis to folate | decreased chemotaxis to cAMP | decreased cAMP level |
DBS0235948 | eppA-/ [act6]: myc: eppA | eppA | wild type |
DBS0350028 | erkA- | erkA | decreased mound size | decreased chemotaxis to cAMP |
DBS0350622 | erkA- | erkA | aberrant development of tipped mound | aberrant stream morphology | abolished protein kinase activation | aberrant cellular response to extracellular stimulus | abolished positive regulation of chemorepellant activity |
DBS0350623 | erkA- | erkA | decreased mound size | precocious development |
DBS0350681 | erkA-/ [act15]: gpaE | erkA | gpaE | wild type |
DBS0350029 | erkA-/ [act15]: mekA: FLAG | erkA | mekA | increased protein localization to cell cortex |
DBS0351474 | erkA-/ regA- | erkA | regA | decreased mound size | aberrant fruiting body morphogenesis |
DBS0351296 | erkB- | erkB | abolished chemotaxis to folate | increased actin filament polymerization | abolished protein phosphorylation |
HS174 | erkB- | erkB | decreased catalytic activity | aberrant phagocytosis | decreased cell motility | decreased prespore gene expression | decreased prestalk gene expression | aberrant sorocarp development | decreased chemotaxis to folate | abolished aggregation | decreased chemotaxis to cAMP | aberrant cell morphology | decreased sporulation |
AK240 | erkB- | erkB | abolished aggregation | decreased sporulation |
DBS0350606 | erkB- | erkB | decreased prespore cell differentiation |
DBS0350683 | erkB-/ [ecmA]: lacZ | erkB | aberrant cell migration to prestalk region |
DBS0350682 | erkB-/ [unk]: erkB(P140S) | erkB | abolished sporulation |
DBS0235949 | erkB-/ regA- | erkB | regA | increased oscillatory cAMP signaling | abolished aggregation |
DBS0350530 | exo1- | exo1 | decreased resistance to bleomycin | decreased double-strand break repair via homologous recombination |
DBS0304864 | expl7- | expl7 | wild type |
DBS0235951 | fadA- | fadA | increased cellular thermotolerance |
DBS0235952 | fadB- | fadB | wild type |
DBS0350240 | fam21- | fam21 | abolished exocytosis | aberrant vegetative growth | decreased protein localization to post-lysosomal vacuole | decreased protein processing in phagocytic vesicle | aberrant autophagic cell death | aberrant phagosome maturation | aberrant lysosome organization |
DBS0236034 | fam45- | fam45 | wild type |
DBS0236040 | fam91- | fam91 | wild type |
DBS0350717 | far1- | far1 | aberrant binding | decreased actin filament polymerization | aberrant defense response to bacterium | aberrant macropinocytosis | decreased growth rate | aberrant phagocytosis | aberrant chemotaxis | decreased engulfment during phagocytosis | decreased chemotaxis to folate | decreased protein kinase activation | decreased folic acid binding | aberrant signal transduction |
DBS0351093 | far1- | far1 | abolished chemotaxis to folate |
DBS0351545 | fatA- | fatA | aberrant lipid storage | decreased phagocytosis |
DBS0235953 | fbxA- | fbxA | decreased sporulation |
HR6 | fbxA- | fbxA | decreased socially cooperative development |
HR42 | fbxA-/ [act15]: myc: fbxA | fbxA | abolished culmination | decreased sporulation |
DBS0235954 | fbxA-/ [ecmA]: GFP(S65T) | fbxA | increased prespore cell differentiation |
HR46 | fbxA-/ regA- | fbxA | regA | aberrant fruiting body morphogenesis | decreased sporulation |
HR48 | fbxA-/ regA- | fbxA | regA | aberrant fruiting body morphogenesis | decreased sporulation |
DBS0235956 | fbxA1- | fbxA | development arrests at slug stage | aberrant fruiting body morphogenesis | increased slug migration | delayed culmination |
DBS0235957 | fbxA2- | fbxA | development arrests at slug stage | aberrant fruiting body morphogenesis | increased slug migration | delayed culmination |
DBS0235958 | fbxA3- | fbxA | development arrests at slug stage | aberrant fruiting body morphogenesis | increased slug migration | delayed culmination |
DG1148 | fcpA- | fcpA | aberrant fruiting body morphogenesis |
DBS0235960 | fcsA- | fcsA | decreased fatty acid level | decreased lipid droplet formation | increased sporulation |
DBS0350128 | fcsB- | fcsB | decreased catalytic activity | decreased phagocytosis |
DBS0350129 | fcsB-/ fcsA- | fcsA | fcsB | decreased catalytic activity | decreased growth rate | delayed development |
DBS0350336 | febA- | febA | wild type |
DBS0350953 | fhbA- | fhbA | increased vegetative cell size | aberrant cellular response to stress |
DBS0350955 | fhbA-/ fhbB- | fhbA | fhbB | aberrant cellular response to stress |
DBS0350954 | fhbB- | fhbB | increased vegetative cell size | aberrant cellular response to stress |
DBS0235961 | fimA- | fimA | decreased vegetative cell size |
HM1253 | fncD2- | fncD2 | decreased resistance to cisplatin |
HM1351 | fncD2-/ rev3- | fncD2 | rev3 | decreased resistance to cisplatin |
HM1405 | fncD2-/ xpf- | fncD2 | xpf | decreased resistance to cisplatin |
HM1416 | fncE- | fncE | decreased resistance to cisplatin |
HM1356 | fncI- | fncI | decreased resistance to cisplatin |
HM1302 | fncL- | fncL | decreased resistance to cisplatin |
HM1407 | fncM- | fncM | decreased resistance to cisplatin |
DBS0235966 | forA- | forA | wild type |
DBS0350667 | forA- | forA | aberrant cellular response to fluid shear stress | decreased cell motility | increased cell motility |
DBS0350669 | forA-/ [act15]: GFP: mhcA | forA | mhcA | aberrant bleb assembly |
DBS0235967 | forA-/ forB- | forA | forB | wild type |
DBS0235968 | forB- | forB | wild type |
DBS0235969 | forC- | forC | aberrant culmination | aberrant fruiting body morphogenesis | development arrests at tipped mound stage |
DBS0350280 | forC- | forC | delayed aggregation | aberrant sorocarp development | decreased chemotaxis to cAMP | decreased sporulation | abolished slug development | delayed gene expression |
DBS0304905 | forC-/ [act15]: GFP: forC | forC | wild type |
DBS0351307 | forE-/ forA-/ forH- | forA | forE | forH | aberrant cortical actin cytoskeleton organization | aberrant cytokinesis | aberrant sorocarp development | decreased cell motility | aberrant cell morphology |
DBS0350287 | forF- | forF | decreased fruiting body size | aberrant phototaxis | increased chemotaxis rate |
DBS0350835 | forG- | forG | decreased growth rate | decreased phagocytosis | aberrant actin cytoskeleton organization | decreased macropinocytosis | aberrant actin filament organization |
DBS0235970 | forH- | forH | decreased cell-substrate adhesion | decreased chemotaxis rate | increased cell motility | aberrant pseudopodium formation | aberrant cell morphology | decreased filopodium formation |
DBS0235971 | forH-/ [act15]: GFP: forH | forH | increased filopodium formation | decreased cell motility | increased cell-substrate adhesion |
HW440 | fpaA(P143A) | fpaA | delayed aggregation | increased response to hypoxia |
HW435 | fpaB-/ AX2 | fpaB-1 | fpaB-2 | decreased response to hypoxia | increased culmination | increased stalk length |
DBS0302506 | frmA- | frmA | delayed aggregation | decreased cell motility | decreased mound size | increased cell-substrate adhesion | aberrant cell morphology |
DBS0304440 | frmA-/ [unk]: GFP | frmA | decreased gene expression | aberrant sorocarp development | increased cell-cell adhesion | delayed development | abolished phototaxis |
DBS0302507 | frmA-/ [unk]: frmA-HA | frmA | wild type |
DBS0350983 | frmB- | frmB | aberrant aggregation | increased mound size | decreased cell-substrate adhesion | increased fruiting body size |
DBS0350232 | fscE- | fscE | aberrant positive regulation of chemorepellant activity | decreased growth rate | aberrant cytokinesis |
DBS0350228 | fslA- | fslA | aberrant cytokinesis |
DBS0350230 | fslB- | fslB | aberrant positive regulation of chemorepellant activity | decreased catalytic activity | aberrant cytokinesis |
DBS0350229 | fslK- | fslK | decreased catalytic activity | aberrant vegetative growth | aberrant cytokinesis |
DBS0350252 | fspA- | fspA | decreased gene expression | aberrant chemotaxis to folate | aberrant vegetative growth |
DBS0350253 | fspA-/ [unk]: fspA: FLAG | fspA | wild type |
DBS0235976 | fszA- | fszA | decreased number of mitochondria | aberrant mitochondrion morphology |
DBS0235978 | fszA-/ fszB- | fszA | fszB | aberrant mitochondrion morphology |
DBS0235980 | fszB- | fszB | aberrant mitochondrion morphology | decreased number of mitochondria | decreased growth rate |
DG1066 | fut1- | fut1 | aberrant fruiting body morphogenesis |
DBS0305025 | gabT- | gabT | precocious development | decreased sporulation |
DBS0305026 | gabT-[pkaC]: pkaC | gabT | pkaC | aberrant protein secretion |
DBS0351298 | gacG- | gacG | increased chemotaxis to folate | increased actin filament polymerization at leading edge |
DBS0351318 | gacG- | gacG | aberrant macropinocytosis | abolished vegetative growth |
DBS0351299 | gacH- | gacH | aberrant chemotaxis to cAMP |
DG1094 | gacT- | gacT | aberrant fruiting body morphogenesis |
DBS0235989 | gadA- | gadA | decreased spore cell differentiation | decreased sporulation |
DBS0350071 | gadA- | gadA | decreased spore germination |
DBS0350077 | gadA-/ gadB- | gadA | gadB | delayed aggregation |
DBS0350072 | gadB- | gadB | delayed aggregation |
DBS0350963 | gapA- | gapA | aberrant cell separation during cytokinesis |
DBS0349924 | gapA- | gapA | decreased actin filament bundle assembly |
DBS0350399 | gapA- | gapA | decreased protein localization to cleavage furrow | increased myosin II assembly | increased lateral pseudopodium formation | aberrant mitotic spindle organization | increased actin filament polymerization | decreased chemotaxis to cAMP | aberrant cellular response to stress |
DBS0350403 | gapA-/ iqgC- | gapA | iqgC | decreased protein kinase activation | decreased chemotaxis to cAMP |
TL198 | gbfA- | gbfA | abolished gene expression | development arrests at mound stage |
DBS0302689 | gbfA- | gbfA | aberrant oscillatory cAMP signaling |
DBS0305094 | gbfA- | gbfA | abolished autophagosome organization | abolished autophagic cell death |
DBS0235994 | gbpC- | gbpC | decreased protein kinase activation | decreased fruiting body size |
DBS0235995 | gbpC- | gbpC | aberrant chemotaxis to cAMP | aberrant myosin II filament organization | decreased chemotaxis rate | aberrant cyclic nucleotide binding | aberrant cell morphology | decreased establishment of cell polarity | decreased fruiting body size |
DBS0302680 | gbpC- | gbpC | abolished protein localization to nucleus | decreased mound size | abolished protein phosphorylation |
DBS0350881 | gbpC- | gbpC | aberrant cyclic nucleotide binding |
DBS0304912 | gbpC-/ [act15]: gbpC | gbpC | wild type |
DBS0304917 | gbpC-/ [act15]: gbpC(1-1698: 2005-2631) | gbpC | decreased chemotaxis to cAMP |
DBS0349868 | gbpC-/ [act15]: gbpC(1-2331: 2470-2631): GFP | gbpC | aberrant stream morphology | decreased chemotaxis to cAMP |
DBS0304918 | gbpC-/ [act15]: gbpC(311-2631) | gbpC | decreased chemotaxis to cAMP |
DBS0304916 | gbpC-/ [act15]: gbpC(F1892A) | gbpC | decreased chemotaxis to cAMP |
DBS0304915 | gbpC-/ [act15]: gbpC(F2082A/ E2084A/ F2564A/ E2566A) | gbpC | decreased chemotaxis to cAMP |
DBS0304913 | gbpC-/ [act15]: gbpC(K342N) | gbpC | decreased chemotaxis to cAMP |
DBS0304914 | gbpC-/ [act15]: gbpC(K905W) | gbpC | decreased chemotaxis to cAMP |
DBS0235996 | gbpC-/ gbpD- | gbpC | gbpD | delayed aggregation | decreased chemotaxis rate | decreased establishment of cell polarity | increased bleb assembly |
DBS0235997 | gbpD- | gbpD | increased establishment of cell polarity | decreased cell-substrate adhesion | decreased lateral pseudopodium formation | increased chemotaxis rate |
DBS0235998 | gbpD-/ [act15]: gbpD | gbpD | increased lateral pseudopodium formation | increased cell-substrate adhesion | decreased chemotaxis rate | aberrant actin filament organization | abolished aggregation |
DG1120 | gbqA- | gbqA | aberrant fruiting body morphogenesis |
DBS0350119 | gcA- | gcA | decreased guanylyl cyclase activity |
DBS0236000 | gca-/ sgcA- | gcA | sgcA | decreased protein kinase activation |
DBS0302679 | gca-/ sgcA- | gcA | sgcA | increased lateral pseudopodium formation | aberrant activation of GTPase activity | aberrant chemotaxis to cAMP | aberrant taxis | aberrant stream morphology | decreased mound size | decreased chemotaxis rate | decreased fruiting body size |
DBS0236002 | gcsA- | gcsA | abolished sporulation | aberrant cellular metabolic process | decreased gene expression | increased gene expression | development arrests at mound stage | abolished vegetative growth | mitotic G1 phase arrest | abolished aggregation | abolished prespore gene expression |
DBS0350387 | gcsA-/ [act15]: carA | carA-1 | carA-2 | gcsA | abolished aggregation |
DBS0236003 | gcsA-/ [act15]: gcsA | gcsA | decreased spore germination | development arrests at mound stage |
DBS0350388 | gcsA-/ [act15]: yakA | gcsA | yakA | wild type |
DBS0236004 | gdt1- | gdt1 | increased gene expression | decreased growth rate | precocious aggregation |
DBS0237190 | gdt1-/ [act15]: pkaR(G135E/ G261A) | gdt1 | pkaR | increased gene expression | abolished aggregation |
DBS0236095 | gdt1-/ gpaB- | gdt1 | gpaB | increased gene expression | abolished aggregation |
DBS0236006 | gdt2- | gdt2 | increased gene expression | precocious aggregation |
DBS0252697 | gefA- | gefA | decreased taxis |
RI19 | gefA- | gefA | decreased actin filament polymerization | decreased gene expression | decreased activation of GTPase activity | abolished activation of adenylate cyclase activity | decreased cGMP-mediated signaling | decreased chemotaxis rate | abolished aggregation | increased protein kinase activation |
JB10 | gefA- | gefA | abolished aggregation |
DBS0350821 | gefA- | gefA | decreased actin filament polymerization | decreased activation of GTPase activity | aberrant chemotaxis to cAMP | decreased protein kinase activation | abolished aggregation |
DBS0350449 | gefA-/ [dscB]: rasG(S17N) | gefA | rasG | decreased actin filament polymerization | decreased activation of GTPase activity | aberrant chemotaxis to cAMP | decreased protein kinase activation |
DBS0351451 | gefB-/ AX2 | gefB | wild type |
DBS0236009 | gefB-/ AX3 | gefB | abolished pinocytosis | delayed aggregation | increased actin filament polymerization | decreased phagocytosis | decreased growth rate | decreased mound size | abolished vegetative growth | aberrant fruiting body morphogenesis | aberrant cell morphology | increased bleb assembly | aberrant cytoskeleton organization |
DBS0236010 | gefB-/ rasS- | gefB | rasS | decreased phagocytosis | increased cell motility |
DBS0236868 | gefC- | gefC | wild type |
DBS0236869 (DBS0235543) | gefD- | gefD | wild type | aberrant activation of GTPase activity |
DBS0236870 | gefE- | gefE | aberrant thermotaxis | aberrant activation of GTPase activity | aberrant phototaxis |
DBS0350569 | gefE- | gefE | decreased activation of GTPase activity | increased gene expression | decreased response to DIF-1 | increased prespore cell differentiation |
DBS0351462 | gefE-/ uduB- | gefE | uduB | wild type |
DBS0351450 | gefF: GFP | gefF | decreased macropinocytosis |
DBS0350822 | gefH- | gefH | decreased actin filament polymerization | decreased activation of GTPase activity | aberrant chemotaxis to cAMP | delayed development | decreased protein kinase activation |
DBS0350823 | gefH-/ gefA- | gefA | gefH | decreased actin filament polymerization | aberrant chemotaxis to cAMP | abolished activation of GTPase activity | decreased protein kinase activation | abolished aggregation |
DBS0236012 | gefK- | gefK | wild type |
DBS0351618 | gefK-/ gacL- | gacL | gefK | decreased response to Gram-negative bacterium | aberrant vegetative growth |
DBS0236871 | gefL- | gefL | aberrant thermotaxis | aberrant phototaxis |
HSB61 | gefM- | gefM | increased cGMP-mediated signaling | decreased lateral pseudopodium retraction | aberrant activation of adenylate cyclase activity | development arrests at mound stage | decreased chemotaxis rate |
DBS0304968 | gefQ- | gefQ | decreased positive regulation of GTPase activity | increased number of mound tips | increased myosin II assembly | increased lateral pseudopodium formation | abolished cell migration to prestalk region | abolished guanyl-nucleotide exchange factor activity | decreased growth rate | decreased fruiting body size | abolished phototaxis |
DBS0304985 | gefQ-/ [act15]: GFP: gefQ(172-654) | gefQ | abolished guanyl-nucleotide exchange factor activity | decreased phototaxis |
DBS0304986 | gefQ-/ [act15]: GFP: gefQ(910-1298) | gefQ | decreased phototaxis |
DBS0236014 | gefR- | gefR | wild type | decreased activation of GTPase activity |
DBS0349892 | gefS- | gefS | wild type |
DBS0349904 | gemA- | gemA | decreased ATP level | decreased growth rate |
DBS0350811 | gflB- | gflB | decreased culmination | decreased protein localization to cell cortex | aberrant G protein-coupled receptor signaling | delayed aggregation | decreased mound size | decreased chemotaxis to cAMP | aberrant protein localization to plasma membrane | increased actin filament polymerization at leading edge | decreased myosin II assembly |
HA201 | gflB- | gflB | decreased phagocytosis | aberrant mitotic actomyosin contractile ring contraction | increased actin filament polymerization | decreased macropinocytosis | increased substrate adhesion-dependent cell spreading |
DBS0350814 | gflB-/ [act15]: GFP: gflB(380-1601,T1180E) | gflB | decreased chemotaxis to cAMP |
DG1109 | ggtA- | ggtA | aberrant fruiting body morphogenesis |
DBS0351210 | gip1- | gip1 | decreased protein localization to plasma membrane | aberrant chemotaxis to cAMP |
DBS0266723 | glcS-/ DH1 | glcS | aberrant stalk morphogenesis | decreased glycogen level | decreased spore size | decreased fruiting body size |
DBS0266765 | glcS-/ HMX | glcS | abolished cellulose biosynthesis | decreased autophagic vacuole organization | aberrant cell morphology |
DBS0350514 | glk- | glk | decreased defense response to Gram-negative bacterium |
DBS0351101 | glkA- | glkA | aberrant aggregation | decreased protein localization to cell cortex | decreased protein level | decreased chemotaxis to cAMP | decreased myosin II assembly | increased activation of GTPase activity | increased protein kinase activation |
DBS0236078 | glpD- | glpD | aberrant glycogen metabolism | aberrant regulation of catalytic activity |
HL250 | gmd(G108D) | gmd | decreased spore germination | decreased growth rate |
DBS0236079 | gmsA- | gmsA | decreased sexual fusion |
DBS0236080 | gmsA- | gmsA | decreased sexual fusion |
HW503 | gnt1(1-253/ H104D) | gnt1 | aberrant stalk morphogenesis | development arrests at slug stage | increased response to hypoxia |
DBS0238384 | gnt14- | gnt14 | wild type |
DBS0238382 | gnt15- | gnt15 | decreased gene expression | decreased growth rate | increased calcium-independent cell-cell adhesion | abolished aggregation | abolished culmination |
DBS0238383 | gnt15- | gnt15 | decreased gene expression | decreased growth rate | increased calcium-independent cell-cell adhesion | abolished aggregation | abolished culmination |
DBS0238390 | gnt15-/ [act15]: FLAG: gnt15 | gnt15 | wild type |
DBS0238391 | gnt15-/ [act15]: FLAG: gnt15 | gnt15 | wild type |
DBS0236081 | gnt2- | gnt2 | abolished catalytic activity | abolished protein modification |
DBS0236082 | gol- | gol | increased resistance to cisplatin |
DBS0235414 | gp130- | gp130 | decreased response to Gram-positive bacterium | decreased cell-substrate adhesion | delayed development | increased growth rate |
DBS0236087 | gpaA- | gpaA | aberrant aggregation | increased stalk length | aberrant response to cAMP | decreased stalk width |
JH131 | gpaA- | gpaA | aberrant cellular homeostasis | wild type | increased growth rate |
DBS0236091 | gpaA-/ [ecmB]: lacZ | gpaA | decreased prestalk gene expression |
DBS0236092 | gpaA-/ [gpaA]: gpaA(G45V) | gpaA | delayed development |
DBS0236093 | gpaA-/ [gpaA]: gpaA(Q206L) | gpaA | increased basal disc size |
DBS0238605 | gpaA-/ rpkA- | gpaA | rpkA | delayed aggregation | abolished aggregation |
DBS0236575 | gpaB- | gpaB | decreased response to cAMP | abolished activation of GTPase activity | aberrant phagocytosis | decreased cGMP-mediated signaling | decreased protein kinase activation | abolished aggregation | abolished chemotaxis to cAMP |
JH104 | gpaB- | gpaB | decreased gene expression | decreased activation of GTPase activity | abolished activation of adenylate cyclase activity | abolished aggregation | abolished chemotaxis to cAMP |
JM1 | gpaB-/ [OE]: carA | carA-1 | carA-2 | gpaB | aberrant calcium-mediated signaling |
DBS0236096 | gpaB-/ [act15]: gpaB | gpaB | abolished aggregation |
DBS0266942 | gpaB-/ [act15]: gpaB | gpaB | delayed aggregation |
DBS0266939 | gpaB-/ [act15]: gpaB(1-345): gpaD(337-345) | gpaB | gpaD | abolished aggregation |
DBS0351103 | gpaB-/ [act15]: gpaB(C4A) | gpaB | abolished protein localization to plasma membrane | decreased cGMP-mediated signaling | abolished aggregation |
DBS0237137 | gpaB-/ [act15]: gpaB(D154V) | gpaB | aberrant aggregation | decreased activation of adenylate cyclase activity | decreased cGMP-mediated signaling | decreased oscillatory cAMP signaling | decreased chemotaxis rate |
DBS0237138 | gpaB-/ [act15]: gpaB(E190G) | gpaB | aberrant aggregation | decreased activation of adenylate cyclase activity | decreased cGMP-mediated signaling | decreased oscillatory cAMP signaling |
DBS0351105 | gpaB-/ [act15]: gpaB(G207A) | gpaB | abolished protein localization to plasma membrane |
DBS0351104 | gpaB-/ [act15]: gpaB(G2A) | gpaB | abolished protein localization to plasma membrane |
DBS0237139 | gpaB-/ [act15]: gpaB(I104S) | gpaB | aberrant aggregation | decreased activation of adenylate cyclase activity | decreased cGMP-mediated signaling | decreased oscillatory cAMP signaling | decreased chemotaxis rate |
DBS0237140 | gpaB-/ [act15]: gpaB(L110S) | gpaB | aberrant aggregation | decreased activation of adenylate cyclase activity | decreased cGMP-mediated signaling | decreased oscillatory cAMP signaling | decreased chemotaxis rate |
DBS0237141 | gpaB-/ [act15]: gpaB(L76P) | gpaB | abolished aggregation |
DBS0237142 | gpaB-/ [act15]: gpaB(N74D) | gpaB | decreased activation of adenylate cyclase activity | decreased cGMP-mediated signaling | decreased oscillatory cAMP signaling | decreased chemotaxis rate | abolished aggregation |
DBS0237143 | gpaB-/ [act15]: gpaB(R64G) | gpaB | decreased chemotaxis rate | abolished aggregation |
DBS0237144 | gpaB-/ [act15]: gpaB(S155P) | gpaB | decreased chemotaxis rate | abolished aggregation |
DBS0351217 | gpaB-/ [act15]: gpaI | gpaB | gpaI | wild type |
DBS0351267 | gpaB-/ [act15]: gpbA: YFP | gpaB | gpbA | abolished aggregation |
DBS0351214 | gpaB-/ [act15]: rasG(S17N) | gpaB | rasG | abolished activation of GTPase activity |
DBS0236097 | gpaB-/ [gpaA]: gpaB | gpaB | abolished aggregation |
DBS0236099 | gpaB-/ [gpaB]: gpaB | gpaB | wild type |
DBS0236098 | gpaB-/ [gpaB]: gpaB(Q208L) | gpaB | aberrant protein localization to plasma membrane |
DBS0350373 | gpaB-/ regA- | gpaB | regA | decreased number of mounds |
DBS0235986 | gpaC- | gpaC | aberrant activation of adenylate cyclase activity | decreased gene expression | increased protein kinase activity | abolished aggregation |
JH417 | gpaD- | gpaD | decreased gene expression | aberrant macropinocytosis | decreased spore cell differentiation | aberrant fruiting body morphogenesis | decreased chemotaxis to folate | decreased protein kinase activation | abolished protein phosphorylation | decreased cGMP biosynthesis | decreased sporulation |
DBS0266944 | gpaD-/ [act15]: gpaB | gpaB | gpaD | aberrant fruiting body morphogenesis | decreased chemotaxis to folate | decreased cGMP biosynthesis |
DBS0266946 | gpaD-/ [act15]: gpaB(1-345): gpaD(337-345) | gpaB | gpaD | aberrant fruiting body morphogenesis | decreased cGMP biosynthesis |
DBS0266943 | gpaD-/ [act15]: gpaD | gpaD | wild type |
DBS0350608 | gpaD-/ [act15]: gpaD(Q200L) | gpaD | development arrests at loose mound stage | decreased chemotaxis to folate | decreased protein kinase activation |
DBS0350607 | gpaD-/ [act15]: gpaD(R107E,R108E) | gpaD | development arrests at slug stage | aberrant slug development |
DBS0266945 | gpaD-/ [act15]: gpaE | gpaD | gpaE | aberrant fruiting body morphogenesis | decreased chemotaxis to folate | decreased cGMP biosynthesis |
DBS0266947 | gpaD-/ [act15]: gpaE(1-339): gpaD(337-345) | gpaD | gpaE | aberrant fruiting body morphogenesis | decreased chemotaxis to folate | decreased cGMP biosynthesis |
DBS0351269 | gpaD-/ [act6]: AEQ | gpaD | aberrant calcium-mediated signaling |
DBS0350374 | gpaD-/ regA- | gpaD | regA | aberrant aggregation | abolished slug migration | decreased sporulation |
DBS0350378 | gpaD-/ regA-/ [ecmB]: lacZ | gpaD | regA | increased prestalk O cell differentiation |
DBS0236101 | gpaE(G196T) | gpaE | wild type |
DBS0236103 | gpaE(Q198L) | gpaE | wild type |
JH257 | gpaE- | gpaE | delayed development of tipped mound | increased chemotaxis to folate | delayed prestalk gene expression | increased vegetative cell size | delayed prespore gene expression | decreased cell migration to prestalk region |
DBS0266941 | gpaE-/ [act15]: gpaE | gpaE | precocious development of tipped mound |
DBS0266948 | gpaE-/ [act15]: gpaE(1-339): gpaD(337-345) | gpaD | gpaE | precocious development of tipped mound |
DBS0350678 | gpaE-/ [act15]: gpaE(K10E/ K11E) | gpaE | delayed development of tipped mound | delayed gene expression |
DBS0350624 | gpaE-/ erkA- | erkA | gpaE | wild type | decreased mound size | precocious development |
LW1 | gpaG- | gpaG | wild type | decreased spore cell differentiation | aberrant GABA signaling pathway |
DBS0236107 | gpaH- | gpaH | wild type | increased cell death | decreased spore germination | abolished negative chemotaxis | increased growth rate | abolished positive regulation of chemorepellant activity | decreased sporulation |
DBS0236108 | gpaH- | gpaH | wild type |
DBS0350972 | gpaH-/ AX2 | gpaH | increased growth rate |
DBS0350975 | gpaH-/ [ecmO]: lacZ | gpaH | aberrant cell differentiation |
DBS0236109 | gpaI- | gpaI | increased number of mounds | aberrant cellular homeostasis | increased establishment of cell polarity | increased cell death | aberrant activation of adenylate cyclase activity | increased chemotaxis to cAMP | precocious aggregation | increased actin filament polymerization | aberrant adaptation of signaling pathway | decreased mound size | decreased oscillatory cAMP signaling | decreased lateral pseudopodium formation | decreased fruiting body size | increased growth rate | aberrant protein localization to plasma membrane | increased cGMP biosynthesis |
DBS0351544 | gpat- | gpat | aberrant lipid storage | decreased lipid droplet formation | increased sporulation | increased phagocytosis |
LW5 | gpbA- | gpbA | aberrant taxis | increased resistance to N-Phenylthiourea | abolished aggregation |
LW6 | gpbA- | gpbA | decreased protein localization to plasma membrane | aberrant cellular homeostasis | aberrant extracellular cAMP signaling pathway | decreased positive regulation of GTPase activity | increased cell death | abolished chemotaxis to folate | aberrant phagocytosis | aberrant chemotaxis | abolished activation of adenylate cyclase activity | decreased cGMP-mediated signaling | decreased engulfment during phagocytosis | aberrant sorocarp development | decreased chemotaxis to folate | decreased protein kinase activation | decreased chemotaxis to cAMP | abolished actin filament polymerization | increased growth rate | aberrant protein localization | aberrant signal transduction |
DBS0351277 | gpbA- | gpbA | aberrant cytokinesis |
DBS0350470 | gpbA-/ [act15]: GFP: cap | cap | gpbA | decreased phagocytosis |
LW14 | gpbA-/ [act15]: carA | carA-1 | carA-2 | gpbA | aberrant calcium-mediated signaling | decreased protein kinase activation | abolished aggregation |
LW17 | gpbA-/ [act15]: carC | carC | gpbA | abolished aggregation |
DBS0351260 | gpbA-/ [act15]: gpbA(A99T/ Y271H/ C335M) | gpbA | abolished activation of adenylate cyclase activity | aberrant fruiting body morphogenesis |
DBS0351261 | gpbA-/ [act15]: gpbA(M30V/ K85R/ S104P/ Q163H) | gpbA | development arrests at mound stage | abolished activation of adenylate cyclase activity | decreased chemotaxis to cAMP |
DBS0351263 | gpbA-/ [act15]: gpbA(M48T/ I52T/ E310G) | gpbA | wild type | decreased activation of adenylate cyclase activity | decreased gene expression | aberrant slug development |
DBS0351259 | gpbA-/ [act15]: gpbA(N147D/ H149R/ N237S) | gpbA | development arrests at mound stage | abolished activation of adenylate cyclase activity | abolished chemotaxis to cAMP |
DBS0351264 | gpbA-/ [act15]: gpbA(R13G/ N74S/ S79P/ H149R/ V178A/ V194R/ F293L) | gpbA | decreased activation of adenylate cyclase activity | decreased gene expression | development arrests at tipped mound stage |
DBS0351262 | gpbA-/ [act15]: gpbA(S196G/ V199D/ C211R) | gpbA | decreased activation of adenylate cyclase activity | aberrant fruiting body morphogenesis |
DBS0351258 | gpbA-/ [act15]: gpbA(V88A/ F229S/ D235V) | gpbA | abolished activation of adenylate cyclase activity | aberrant fruiting body morphogenesis | decreased chemotaxis to cAMP |
DBS0351268 | gpbA-/ [act6]: AEQ | gpbA | aberrant calcium-mediated signaling |
HO547 | gpbA-/ [act6]: FRB: [act15]: RFP: gpbA/ [act15]: cnxA: CFP: FKBP/ [act15]: limE(1-145): GFP | gpbA | aberrant cortical actin cytoskeleton organization |
HO543 | gpbA-/ [act6]: FRB: [act15]: RFP: gpbA/ [act15]: cnxA: YFP: FKBP | gpbA | abolished chemotaxis to folate |
DBS0351198 | gpbA-/ [act6]: yakA | gpbA | yakA | abolished vegetative growth |
DBS0350832 | gpbA-/ [unk]: gpbA(Q208L) | gpbA | aberrant adaptation of signaling pathway |
DBS0351278 | gpbA-/ mhcA- | gpbA | mhcA | aberrant cytokinesis |
AK1353 | gpi- | gpi | decreased response to Gram-positive bacterium |
DBS0350477 | gpr89- | gpr89 | aberrant spore morphology | aberrant mitochondrion morphology | abolished cell migration to prestalk region | decreased gene expression | aberrant slug development | abolished vegetative growth | decreased cell motility | decreased fruiting body size | precocious gene expression | decreased phototaxis | delayed gene expression |
DBS0350479 | gpr89-/ [act15]: gpr89: GFP | gpr89 | wild type |
DBS0304814 | grlA- | grlA | delayed prestalk gene expression | decreased prestalk gene expression | decreased spore cell differentiation | decreased sporulation | delayed culmination |
DBS0304815 | grlA-/ [act15]: grlA: GFP | grlA | aberrant development of tipped mound |
DBS0350074 | grlB- | grlB | decreased small molecule binding | aberrant positive regulation of chemorepellant activity | delayed aggregation | aberrant vegetative growth | delayed gene expression |
DBS0350078 | grlB-/ grlE- | grlB | grlE | decreased small molecule binding | delayed aggregation |
DBS0350227 | grlD- | grlD | aberrant positive regulation of chemorepellant activity | decreased growth rate | aberrant cytokinesis | abolished small molecule binding | aberrant cellular response to extracellular stimulus |
DBS0236112 | grlE- | grlE | decreased spore cell differentiation | aberrant GABA signaling pathway | decreased sporulation |
DBS0236113 | grlE- | grlE | delayed aggregation | aberrant gene expression | decreased chemotaxis to cAMP |
DBS0350075 | grlE- | grlE | decreased spore germination | delayed aggregation |
DBS0350226 | grlH- | grlH | aberrant positive regulation of chemorepellant activity | aberrant protein level | aberrant vegetative growth | abolished activation of GTPase activity | decreased protein binding | increased growth rate |
DBS0351147 | grlH-/ [act15]: grlH | grlH | wild type |
DBS0238865 | grlJ- | grlJ | increased migratory slug size | aberrant spore morphology | decreased spore germination | precocious development | decreased fruiting body size | precocious gene expression |
DBS0350283 | grlJ- | grlJ | aberrant spore morphology | increased resistance to N-Phenylthiourea |
DBS0238866 | grlJ-/ [act15]: grlJ: GFP | grlJ | wild type |
DBS0350284 | grlJ-/ [act15]: grlJ: GFP | grlJ | wild type |
DBS0238686 | grpA- | grpA | decreased spore germination | abolished protein secretion |
DBS0238687 | grpA-/ [act15]: grpA-FLAG | grpA | wild type |
ARK200 | gskA- | gskA | abolished stream development | increased gene expression | decreased gene expression | increased protein localization to plasma membrane | decreased chemotaxis to cAMP | decreased sporulation |
DBS0236114 | gskA- | gskA | aberrant aggregation | decreased protein localization to cell cortex | decreased slug migration | aberrant sorus morphology | aberrant extracellular cAMP signaling pathway | decreased gene expression | abolished protein localization to plasma membrane | abolished protein phosphorylation | decreased chemotaxis to folate | decreased stalk length | abolished chemotaxis to cAMP |
HM338 | gskA- | gskA | precocious aggregation | decreased prespore cell differentiation | aberrant mitotic spindle elongation | aberrant fruiting body morphogenesis | increased prestalk cell differentiation | decreased sporulation |
DBS0349930 | gskA-/ [act15]: GFP: tacA | gskA | tacA | increased protein localization to nucleus |
DBS0349881 | gskA-/ [act15]: gskA(Y214F) | gskA | abolished stream development |
DBS0349800 | gskA-/ [ecmA]: LacZ | gskA | aberrant prestalk gene expression |
DBS0349801 | gskA-/ [ecmB]: LacZ | gskA | aberrant prestalk gene expression |
DBS0350260 | gskA-/ [unk]: pikA(1-492(S7D/ S11D/ S109D/ S113D/ S177D/ S181D)) | gskA | pikA | wild type |
DBS0351102 | gskA-/ glkA- | glkA | gskA | aberrant sorocarp development | decreased chemotaxis to cAMP | increased protein kinase activation |
DBS0350427 | gskA-/ gskA(K85R): GFP | gskA | aberrant aggregation |
DBS0350426 | gskA-/ gskA: GFP | gskA | wild type |
DBS0350988 | gst4- | gst4 | decreased fruiting body size |
DBS0266891 | gtaC- | gtaC | decreased mound size | aberrant stream morphology | abolished stalk cell differentiation | aberrant prestalk B cell differentiation |
DBS0350347 | gtaC- | gtaC | abolished gene expression | decreased fruiting body size | abolished aggregation |
DBS0350348 | gtaC-/ [act15]: GFP: gtaC | gtaC | wild type |
DBS0350357 | gtaC-/ [act15]: GFP: gtaC(C500,503,522,525S) | gtaC | aberrant gene expression | abolished aggregation | decreased fruiting body size |
DBS0350358 | gtaC-/ [act15]: GFP: gtaC(T376A/ S379,380A/ C500,503,522,525S) | gtaC | aberrant protein localization to nucleus |
DBS0350361 | gtaC-/ [act15]: gtaC: (468-496): GFP: gtaC | gtaC | development arrests at mound stage | decreased mound size | precocious development |
DBS0266892 | gtaC-KD | gtaC | abolished stalk cell differentiation |
DBS0266893 | gtaC-KD/ [act15]: GFP: gtaC | gtaC | wild type |
DBS0351091 | gtaG- | gtaG | decreased gene expression | development arrests at slug stage | aberrant slug development | decreased prestalk A cell differentiation | decreased sporulation |
DBS0236120 | gxcA- | gxcA | decreased activation of GTPase activity | decreased actin filament polymerization | delayed development |
DBS0236121 | gxcB- | gxcB | decreased exocytosis | delayed development | aberrant cytoskeleton organization |
DBS0350256 | gxcC- | gxcC | delayed development |
DBS0350257 | gxcC-/ [act15]: GFP: gxcC | gxcC | wild type |
DBS0238825 | gxcDD- | gxcDD | aberrant stream morphology | delayed development |
LAS105 | gxcKK- | gxcKK | decreased socially cooperative development |
DBS0350268 | gxcT- | gxcT | aberrant activation of GTPase activity | increased lateral pseudopodium formation | aberrant cytokinesis | decreased growth rate | delayed aggregation | decreased establishment of cell polarity | decreased chemotaxis to cAMP | decreased fruiting body size | aberrant protein localization to plasma membrane |
DBS0350269 | gxcT-/ [act15]: GFP: gxcT | gxcT | wild type |
DBS0350656 | hatA-/ [hatB]: hatB | hatA | hatB | aberrant cellular response to stress |
DBS0236129 | hbx2- | hbx2 | wild type |
DBS0236130 | hbx2- | hbx2 | wild type |
DBS0236131 | hbx2-/ warA- | hbx2 | warA | increased basal disc size | development arrests at mound stage | decreased prespore cell differentiation | increased prestalk O cell differentiation |
DBS0350324 | hbx4-/ [ecmAO]: lacZ | hbx4 | increased prespore cell differentiation |
DBS0350879 | hbx9- | hbx9 | decreased cell-cell adhesion | decreased gene expression | delayed aggregation | decreased growth rate | decreased chemotaxis to cAMP |
DBS0350880 | hbx9-/ [ecmA]: lacZ | hbx9 | increased prestalk A cell differentiation |
DBS0236153 | hcpA- | hcpA | decreased growth rate |
DBS0236157 | hcpB- | hcpB | wild type |
DBS0305109 | hdaB- | hdaB | decreased sporulation | decreased histone deacetylase activity |
HM1012 | helC- | helC | decreased gene expression | delayed development | aberrant fruiting body morphogenesis |
HM444 | helC- | helC | decreased gene expression | aberrant fruiting body morphogenesis | delayed development |
DG1059 | helE- | helE | increased slug migration |
DBS0236163 | helF- | helF | increased migratory slug size | increased stalk cell differentiation | delayed development | increased post-transciptional gene silencing by RNA |
DBS0350878 | hephA- | hephA | increased response to cAMP | delayed aggregation | aberrant sorocarp development | decreased cAMP level |
DBS0350362 | hfnA- | hfnA | increased phototaxis | decreased migratory slug size | increased slug migration |
DBS0350363 | hfnA-/ [ecmO]: lacZ | hfnA | aberrant slug development | aberrant prestalk O cell differentiation |
DBS0350364 | hfnA-/ abpC- | abpC | hfnA | wild type | aberrant prestalk O cell differentiation | decreased phototaxis |
DBS0351593 | hgrA- | hgrA | matA | aberrant macrocyst formation |
DBS0351590 | hgrA-/ KAX3 | hgrA | aberrant macrocyst formation |
DBS0351594 | hgrB- | hgrB | matA | aberrant macrocyst formation |
DBS0351591 | hgrB-/ KAX3 | hgrB | aberrant macrocyst formation |
DBS0238583 | hipA- | hipA | decreased spore germination | aberrant spore morphology | aberrant cortical actin cytoskeleton organization | aberrant spore coat morphology | increased protein localization to plasma membrane |
DBS0305951 | hipA-/ epnA- | epnA | hipA | decreased spore germination | aberrant spore morphology |
DBS0351165 | hspb1- | hsbp1-1 | hsbp1-2 | decreased exocytosis | decreased protein level | aberrant protein localization to lysosomal membrane |
DBS0351532 | hspc300-/ AX2 | hspc300 | aberrant macropinocytosis | aberrant cytokinesis | decreased cell motility | decreased filopodium formation | abolished protein level |
DBS0350289 | hspc300-/ [act15]: myc: hspc300 | hspc300 | wild type |
DBS0252818 | hssA- | hssA | wild type |
DBS0351066 | htmA- | htmA | decreased gene expression | aberrant sorocarp development | increased cell-substrate adhesion | decreased cell motility |
DBS0349776 | htt- | htt | aberrant cell separation during cytokinesis | decreased growth rate | decreased chemotaxis rate | delayed development | delayed gene expression | decreased myosin II assembly |
DBS0349788 | htt- | htt | aberrant aggregation | abolished stream development | development arrests at loose mound stage | aberrant cellular response to starvation | aberrant spore morphology | decreased spore germination | abolished cell motility in response to calcium ion | increased number of mound tips | aberrant sorocarp development | aberrant hypotonic response | aberrant actin filament organization | abolished culmination | decreased sporulation | aberrant prespore cell differentiation | abolished calcium-independent cell-cell adhesion | abolished protein level | abolished chemotaxis to cAMP |
DBS0351281 | htt- | htt | abolished gene expression | aberrant sorus morphology | decreased gene expression | decreased growth rate | aberrant slug development | aberrant sorocarp development | delayed development | decreased cAMP level | aberrant prestalk cell differentiation |
DBS0349786 | htt-/ [act15]: htt: GFP | htt | wild type | aberrant protein level |
DBS0350438 | ibrA- | ibrA | aberrant substrate adhesion-dependent cell spreading | aberrant contractile vacuole organization | decreased phagocytosis | decreased growth rate | aberrant cytokinesis | aberrant hypotonic response | decreased contractile vacuole discharge |
DBS0349794 | ibrA- | ibrA | aberrant stalk development |
DBS0252699 | icmA- | icmA-1 | icmA-2 | abolished sporulation | abolished stream development | aberrant extracellular cAMP signaling pathway | abolished establishment of cell polarity | development arrests at mound stage | abolished vegetative growth | aberrant oscillatory cAMP signaling | aberrant fruiting body morphogenesis | aberrant protein localization to nucleus | delayed gene expression | aberrant protein localization |
DBS0252702 | icmA-/ [act15]: TAP: YFP: rasG | icmA-1 | icmA-2 | rasG | abolished C-terminal protein methylation |
DBS0252701 | icmA-/ [act15]: hICMT | icmA-1 | icmA-2 | wild type |
DBS0252700 | icmA-/ [act15]: icmA | icmA-1 | icmA-2 | wild type |
DBS0236421 | icpA- | icpA | abolished protein localization to mitotic spindle | aberrant mitosis | aberrant cytokinesis | abolished protein localization to cleavage furrow | abolished protein localization to mitotic spindle midzone | aberrant protein localization |
DBS0238521 | icpA-/ [act15]: GFP: icpA(1-1013) | icpA | aberrant protein localization to mitotic spindle |
BS153 | ifkA- | ifkA | increased mound size | precocious aggregation | precocious gene expression | decreased protein secretion |
BS161 | ifkA-/ ifkB- | ifkA | ifkB | increased mound size | increased number of mound tips | increased cell-cell adhesion | increased cell-substrate adhesion | aberrant fruiting body morphogenesis |
BS160 | ifkB- | ifkB | increased prestalk gene expression |
DBS0236425 | ino1- | ino1 | increased number of mound tips | decreased phagocytosis | abolished vegetative growth | increased 2,3-bisphosphoglycerate level | decreased myo-inositol level |
DBS0350801 | ino1- | ino1 | aberrant cellular metabolic process | increased number of autophagosomes | decreased cell-substrate adhesion | aberrant phosphatidylinositol metabolism | aberrant cytokinesis | abolished vegetative growth | aberrant fruiting body morphogenesis | decreased myo-inositol level |
DBS0266326 | iplA- | iplA | abolished cellulose biosynthesis | abolished autophagosome organization | abolished autophagic cell death | aberrant autophagic cell death |
HM1038 | iplA- | iplA | aberrant cell motility | precocious aggregation | delayed aggregation | aberrant chemotaxis | aberrant calcium-mediated signaling | increased bleb assembly | increased chemotaxis to arachidonic acid | abolished positive regulation of chemorepellant activity |
DBS0351539 | iplA-/ AX2 | iplA | abolished response to DIF-1 | abolished response to cAMP | aberrant GABA signaling pathway |
DBS0350439 | iplA-/ [act15]: GFP: iplA | iplA | wild type |
DBS0252878 | iptA- | iptA | decreased spore germination | aberrant sporulation |
DBS0350400 | iqgC- | iqgC | decreased myosin II assembly |
DBS0351225 | iqgC- | iqgC | aberrant cytokinesis | increased macropinocytosis | increased phagocytosis |
DBS0351435 | ireA- | ireA | increased number of autophagosomes | decreased protein level | aberrant vacuole organization | aberrant gene expression | aberrant cellular response to stress | aberrant endoplasmic reticulum organization | aberrant protein localization |
DBS0351436 | ireA-/ [act15]: ireA(K603N): GFP | ireA | decreased protein level | aberrant endoplasmic reticulum organization | aberrant cellular response to stress |
DBS0351437 | ireA-/ [act15]: ireA(N927A): GFP | ireA | decreased protein level | aberrant endoplasmic reticulum organization | aberrant cellular response to stress |
DBS0236031 | kctd9- | kctd9 | wild type |
DBS0350057 | keaA- | keaA | aberrant extracellular cAMP signaling pathway | decreased gene expression | delayed aggregation | decreased growth rate | decreased cAMP level |
DBS0350472 | kif1- | kif1 | aberrant transport |
DBS0350959 | kif10-/ [act15]: dhcA(1384-4725) | dhcA | kif10 | wild type |
DBS0350038 | kif11- | kif11 | wild type |
DBS0236489 | kif12- | kif12 | aberrant protein localization to mitotic spindle | aberrant cell separation during cytokinesis | aberrant cytokinesis | aberrant myosin II filament organization | increased bleb assembly |
DBS0236490 | kif12-/ [act15]: FLAG: kif12 | kif12 | wild type |
DBS0302534 | kif13- | kif13 | precocious mitotic spindle elongation | aberrant mitotic spindle organization |
DBS0350039 | kif4- | kif4 | decreased growth rate |
DBS0350042 | kif4-/ [act15]: dhcA(1384-4725) | dhcA | kif4 | aberrant mitotic spindle organization |
DBS0350021 | kif5- | kif5 | wild type |
DBS0350022 | kif5-/ [act15]: FLAG: kif5 | kif5 | aberrant cytokinesis | aberrant cell morphology |
DBS0350023 | kif5-/ [act15]: FLAG: kif5(342-990) | kif5 | aberrant cell morphology |
DBS0350024 | kif5-/ [act15]: GFP: kif5(805-990) | kif5 | aberrant cytokinesis |
DBS0236494 | kif7- | kif7 | decreased cell migration to prestalk region |
DBS0350040 | kif8- | kif8 | aberrant microtubule cytoskeleton organization |
DBS0350947 | kif8-/ [act15]: dhcA(1384-4725) | dhcA | kif8 | wild type |
DBS0349964 | kif9- | kif9 | aberrant mitotic spindle organization | aberrant mitosis | decreased growth rate | aberrant protein localization to nuclear envelope | aberrant centrosome localization | aberrant centromere complex assembly | aberrant centrosome organization |
DBS0236491 | kil1- | kil1 | abolished defense response to Gram-negative bacterium | increased defense response to fungus |
DBS0351457 | kil1-/ lrrkA- | drkD | kil1 | aberrant defense response to bacterium |
DBS0350043 | kil2- | kil2 | aberrant response to cation stress | aberrant defense response to bacterium | decreased protein processing in phagocytic vesicle | abolished defense response to Gram-negative bacterium | increased defense response to fungus |
DBS0350874 | kil2- | kil2 | aberrant defense response to bacterium | decreased growth rate |
DBS0350044 | kil2-/ [act15]: kil1 | kil1 | kil2 | abolished defense response to bacterium |
DBS0351458 | kil2-/ lrrkA- | drkD | kil2 | aberrant defense response to bacterium |
DBS0350875 | kil2-/ vps13F- | kil2 | vps13F | aberrant defense response to bacterium | decreased growth rate |
DBS0351502 | knkA- | knkA | decreased spore germination | aberrant spore morphology | decreased number of autophagosomes | decreased prespore gene expression | aberrant fruiting body morphogenesis | aberrant phototaxis | decreased sporulation |
DBS0236492 | krsA- | krsA | decreased chemotaxis to cAMP |
DBS0238720 | krsA- | krsA | abolished stream development | precocious culmination | abolished activation of adenylate cyclase activity | decreased vegetative cell size | decreased mound size | aberrant hyperosmotic response | precocious gene expression | decreased cAMP level |
DBS0236493 | krsA-/ [act15]: GFP: krsA | krsA | wild type |
DBS0238721 | krsA-/ [act15]: GFP: krsA | krsA | wild type |
DBS0238722 | krsA-/ [act15]: GFP: krsA(K49R) | krsA | aberrant stream morphology |
DBS0238723 | krsA-/ [act15]: GFP: krsA(T173A) | krsA | abolished stream development |
DBS0238725 | krsA-/ [act15]: GFP: krsA(deltaC) | krsA | aberrant stream morphology |
DBS0238724 | krsA-/ [act15]: GFP: krsA(deltaKinase) | krsA | abolished stream development |
DBS0238726 | krsA-/ [act15]: GFP: krsA(deltaNS) | krsA | abolished stream development |
DBS0350598 | krsB- | krsB | aberrant stream morphology | decreased cell motility | increased cell-substrate adhesion | delayed development | decreased chemotaxis to cAMP |
DBS0350599 | krsB-/ [tet]: krsB(T176A): GFP | krsB | aberrant stream morphology |
DBS0350600 | krsB-/ krsA- | krsA | krsB | aberrant stream morphology | delayed development |
DBS0236495 | ku80- | ku80 | decreased resistance to bleomycin | decreased double-strand break repair via nonhomologous end joining |
DBS0350536 | ku80-/ dclre1- | dclre1 | ku80 | wild type |
DBS0350537 | ku80-/ myc: ku80(1-782) | ku80 | decreased double-strand break repair via nonhomologous end joining |
DBS0236498 | lagD- | tgrD1 | aberrant aggregation | abolished stream development | aberrant extracellular cAMP signaling pathway |
DBS0236499 | limB- | limB | decreased cell-substrate adhesion | abolished cell migration to prestalk region | development arrests at mound stage | delayed prestalk gene expression | aberrant cell-cell adhesion | decreased prestalk gene expression | decreased chemotaxis rate | aberrant actin filament organization | decreased establishment of cell polarity |
DBS0236502 | limB-/ [act15]: paxB: GFP | limB | paxB | development arrests at mound stage |
DBS0236500 | limB-/ [cotC]: limB | limB | development arrests at mound stage |
DBS0236501 | limB-/ [ecmAO]: limB | limB | wild type |
DBS0236729 | limB-/ paxB- | limB | paxB | development arrests at mound stage |
DBS0350563 | limC- | limC | delayed aggregation | decreased growth rate | aberrant cytokinesis | aberrant response to osmotic stress |
DBS0350564 | limD1- | limD1 | increased lateral pseudopodium formation | delayed aggregation | decreased growth rate | aberrant cytokinesis | aberrant response to osmotic stress | decreased chemotaxis to cAMP | decreased establishment of cell polarity | aberrant actin filament organization |
DBS0350565 | limD1-/ limC- | limC | limD1 | delayed aggregation | aberrant cytokinesis | abolished vegetative growth | aberrant response to osmotic stress | decreased chemotaxis to cAMP | aberrant actin filament organization | decreased establishment of cell polarity |
DBS0236503 | limE- | limE | aberrant cytokinesis |
DBS0236506 | limF- | limF | decreased phagocytosis |
DBS0236511 | lipA- | lipA | wild type |
DBS0236512 | lipA- | lipA | wild type |
DG1006 | lipA- | lipA | abolished culmination |
DG1056 | lipB- | captC | aberrant fruiting body morphogenesis |
DBS0236515 | lis1(D327H) | lis1 | aberrant microtubule cytoskeleton organization | increased actin phosphorylation | aberrant Golgi localization |
DBS0349950 | lmbd2B- | lmbd2B | aberrant chemotaxis | delayed development | aberrant cell morphology | increased pseudopodium formation |
DBS0349982 | lmnB- | lmnB | aberrant chromatin assembly | aberrant centrosome localization |
DBS0350354 | lmpA- | lmpA | decreased lysosomal protein degradation | decreased pinocytosis | decreased protein level | decreased phagocytosis | decreased growth rate | decreased cell motility | decreased protein processing in phagocytic vesicle | aberrant phagosome maturation | decreased fruiting body size | decreased defense response to Gram-positive bacterium | decreased sporulation |
DBS0351481 | lmpB- | lmpB | decreased phagocytosis |
DBS0351482 | lmpC- | lmpC | decreased protein localization to cell surface | increased protein localization to cell surface |
DBS0350452 | lpten- | lpten | aberrant cell motility | decreased lateral pseudopodium retraction |
DBS0350453 | lpten-/ [act15]: lpten: RFP | lpten | wild type |
DBS0236516 | lrrA- | lrrA | increased mound size | decreased spore germination | decreased cell-substrate adhesion | abolished establishment of cell polarity | decreased gene expression | development arrests at mound stage | increased actin filament polymerization | abolished positive chemotaxis | abolished aggregation | delayed gene expression |
DBS0350407 | lrrB- | lrrB | aberrant thermotaxis | delayed slug development | aberrant gene expression | aberrant sorocarp development | decreased prestalk gene expression | aberrant phototaxis | aberrant late culminant morphology |
DBS0350478 | lrrB-/ [ecmB]: lacZ | lrrB | aberrant prestalk B cell differentiation |
DBS0350476 | lrrB-/ [ecmO]: lacZ | lrrB | aberrant prestalk O cell differentiation |
DBS0351456 | lrrkA- | drkD | aberrant defense response to bacterium | decreased protein processing in phagocytic vesicle | abolished vegetative growth |
DBS0236517 | lst8- | lst8 | aberrant activation of adenylate cyclase activity | decreased actin filament polymerization | decreased chemotaxis rate | abolished aggregation | decreased myosin II assembly | abolished positive regulation of chemorepellant activity |
DBS0350106 | lst8- | lst8 | increased phagocytosis |
DBS0350114 | lst8-/ [act15]: GFP: rheb(Q64L) | lst8 | rheb | increased phagocytosis |
DBS0309063 | lvsA- | lvsA | increased bleb assembly |
AD60 | lvsA- | lvsA | abolished cytokinesis | decreased pinocytosis | aberrant contractile vacuole organization | decreased phagocytosis | aberrant hypotonic response | increased cell-substrate adhesion |
AD63 | lvsA- | lvsA | abolished cytokinesis | abolished contractile vacuole dissociation from plasma membrane | aberrant calcium-mediated signaling |
DBS0237207 | lvsA-/ [act6]: GFP: lvsA(1828- 3619) | lvsA | abolished cytokinesis |
DBS0236521 | lvsB- | lvsB | increased secretion of lysosomal enzymes | increased lysosome size | increased exocytosis | increased pinocytosis | aberrant protein localization to post-lysosomal vacuole | aberrant phagosome maturation | increased endosome size | aberrant post-lysosomal vacuole exocytosis | increased endosomal vesicle fusion | aberrant lysosome organization |
DBS0350567 | lvsB-/ [act15]: FLAG: Rab14(N121I) | lvsB | rab14 | wild type |
DBS0238218 | lvsB-[act6]: TAP: GFP: lvsB | lvsB | wild type |
DBS0236522 | lvsC- | lvsC | wild type |
DBS0236523 | lvsD- | lvsD | wild type |
DBS0236524 | lvsE- | lvsE | wild type |
DBS0236525 | lvsF- | lvsF | wild type |
DBS0351162 | lyC2- | lyC2 | decreased growth rate |
DBS0349933 | macA- | macA | aberrant macrocyst formation | decreased sexual fusion |
DBS0236536 | malA- | malA | wild type |
DBS0351251 | matA- | matA | abolished mating type determination |
HM1524 | matA- | matA | abolished mating type determination |
DBS0350211 | mef2A- | mef2A | decreased growth rate | aberrant sorocarp development | aberrant stream morphology | decreased sporulation |
DBS0350212 | mef2A- | mef2A | decreased growth rate | aberrant stream morphology | aberrant sorocarp development | aberrant gene expression | decreased sporulation |
DBS0350213 | mef2A-/ [ecmA]: lacZ | mef2A | aberrant prestalk A cell differentiation |
DBS0350214 | mef2A-/ [ecmB]: lacZ | mef2A | aberrant prestalk B cell differentiation |
DBS0350215 | mef2A-/ [pspA]: lacZ | mef2A | decreased prespore cell differentiation |
DBS0236543 | mekA- | mekA | decreased mound size | precocious development | abolished chemotaxis to cAMP |
DBS0350030 | mekA-/ [act15]: Myc: erkA | erkA | mekA | abolished protein localization to cell cortex |
DBS0350036 | mekA-/ [act15]: mekA(299-360) | mekA | decreased mound size |
DBS0350035 | mekA-/ [act15]: mekA(K321A) | mekA | decreased mound size |
DBS0350032 | mekA-/ [act15]: mekA(S444A/ T448A) | mekA | decreased mound size |
DBS0350031 | mekA-/ [act15]: mekA(S444E/ T448E) | mekA | development arrests at mound stage |
DBS0238098 | mekA-/ ppp4C- | mekA | ppp4c | decreased mound size |
DBS0238109 | mekA-/ ppp4C-/ [act15]: FLAG: pppC | ppp4c | decreased mound size | precocious development |
DBS0236542 | mekA-/ smkA- | mekA | smkA | decreased mound size |
DBS0236544 | mfeA- | mfeA | aberrant cellular metabolic process | decreased protein level | aberrant extracellular cAMP signaling pathway | development arrests at mound stage |
DBS0351543 | mfsd8- | mfsd8 | increased protein secretion |
DBS0266843 | mgp1- | mgp1 | increased phototaxis | abolished stream development | increased filopodium formation | aberrant contractile vacuole organization | decreased cell motility | decreased fruiting body size | decreased stalk width | decreased stalk length |
DBS0266846 | mgp1-/ mgp2- | mgp1 | mgp2 | increased filopodium formation | aberrant contractile vacuole organization | aberrant culmination | decreased cell motility | decreased phototaxis | decreased stalk length |
DBS0266844 | mgp2- | mgp2 | increased migratory slug size | increased mound size |
HS1 | mhcA- | mhcA | development arrests at mound stage | aberrant cytokinesis | decreased growth rate | increased actin filament polymerization | aberrant hypotonic response | aberrant regulation of GTPase activity | abolished bleb assembly | aberrant regulation of protein kinase activity | aberrant cellular response to stress |
HS2205 | mhcA- | mhcA | abolished cell motility | decreased cell motility |
HS2207 | mhcA- | mhcA | abolished cytokinesis | development arrests at mound stage |
DBS0350064 | mhcA- | mhcA | decreased cell motility | decreased establishment of cell polarity |
HS2206 | mhcA- | mhcA | aberrant cellular response to fluid shear stress | abolished bleb assembly |
HK321 | mhcA- | mhcA | aberrant cortical actin cytoskeleton organization | aberrant chemotaxis to folate | aberrant cell morphology |
HK323 | mhcA- | mhcA | decreased cell motility | aberrant stream morphology |
DBS0266674 | mhcA-/ [act15]: GFP: abpC(9-148) | abpC | mhcA | decreased uropod retraction | decreased pseudopodium retraction |
DBS0237564 | mhcA-/ [act15]: GFP: ctxA/ [RNAi]enlA | ctxA | enlA | mhcA | aberrant mitotic actomyosin contractile ring contraction |
DBS0266675 | mhcA-/ [act15]: GFP: mhcA(E476K) | mhcA | decreased pseudopodium retraction |
DBS0350489 | mhcA-/ [act15]: GFP: mhcA/ [RNAi]rmd1 | mhcA | rmd1 | abolished protein localization to cleavage furrow |
DBS0236548 | mhcA-/ [act15]: GFP: pats1(2087-2351) | mhcA | pats1 | aberrant cytokinesis |
DBS0350291 | mhcA-/ [act15]: gppA: GFP | gppA | mhcA | aberrant contractile vacuole morphology | decreased contractile vacuole discharge |
DBS0236549 | mhcA-/ [act15]: limE(1-145): GFP | limE | mhcA | increased actin filament polymerization |
DBS0350808 | mhcA-/ [act15]: mhcA(1-933: 1455-2116] | mhcA | wild type | aberrant cytokinesis | aberrant fruiting body morphogenesis |
DBS0238158 | mhcA-/ [act15]: mhcA(81-2116) | mhcA | decreased growth rate | development arrests at tipped mound stage |
CW0401 | mhcA-/ [act15]: mhcA(T1823A/ T1833A/ T2029A) | mhcA | increased myosin II assembly | decreased growth rate | aberrant chemotaxis |
DBS0236550 | mhcA-/ [act15]: mhcA(T1823A/ T1833A/ T2029A) | mhcA | decreased filopodium formation |
DBS0236551 | mhcA-/ [act15]: mhcA(T1823D/ T1833D/ T2029D) | mhcA | increased filopodium formation |
DBS0238399 | mhcA-/ [act15]: rapA(G12V) | mhcA | rapA | increased establishment of cell polarity | increased actin filament polymerization | aberrant myosin II filament organization |
DBS0236552 | mhcA-/ [mhcA]: mhcA(1-1224) | mhcA | aberrant cytokinesis | development arrests at mound stage |
DBS0350948 | mhcA-/ [mhcA]: mhcA(1-1224)/ [act15]: mhcA(E683K) | mhcA | aberrant catalytic activity |
DBS0350949 | mhcA-/ [mhcA]: mhcA(1-1224)/ [act15]: mhcA(R686C) | mhcA | aberrant catalytic activity |
DBS0238157 | mhcA-/ [mhcA]: mhcA(1-1224)/ [act15]: mhcA(R689H) | mhcA | decreased actin filament sliding |
DBS0236547 | mhcA-/ [unk]: GFP: icpA | icpA | mhcA | decreased protein localization to cleavage furrow |
DBS0350668 | mhcA-/ forA- | forA | mhcA | abolished cell motility | decreased cell motility |
DBS0351411 | mhcA-/ piaA- | mhcA | piaA | aberrant cytokinesis |
CW0371 | mhkA- | mhkA | increased myosin II assembly | aberrant chemotaxis | decreased cell motility | aberrant protein localization to pseudopodium |
DBS0236557 | mhkA-/ [act15]: mhkA | mhkA | decreased growth rate | development arrests at mound stage | aberrant cytokinesis | decreased myosin II assembly |
CW0431 | mhkA-/ mhkB-/ mhkC- | mhkA | mhkB | mhkC | increased myosin II assembly | decreased growth rate | aberrant cytokinesis | aberrant chemotaxis | decreased cell motility |
DBS0236556 | mhkA-/ mhkC- | mhkA | mhkC | increased myosin II assembly | decreased growth rate | aberrant cytokinesis |
CW0394 | mhkA/ mhkB | mhkA | mhkB | increased myosin II assembly | decreased growth rate | aberrant cytokinesis |
CW0166 | mhkB- | mhkB | increased myosin II assembly | decreased cell motility |
CW0403 | mhkC- | mhkC | increased myosin II assembly | aberrant cytokinesis | aberrant chemotaxis |
DG1069 | mhkC- | mhkC | aberrant fruiting body morphogenesis |
CW0435 | mhkD- | mhkD | increased myosin II assembly | decreased cell motility |
DBS0236559 | midA- | midA | decreased pinocytosis | aberrant cellular homeostasis | aberrant spore morphology | decreased glycogen level | increased ammonia level | decreased thermotaxis | increased autophagy | decreased mitochondrial fission | decreased growth rate | decreased phagocytosis | decreased vegetative cell size | increased slug migration | increased glutamate level | decreased phototaxis |
DBS0350123 | midA-/ [act15]: GFP: atg18 | atg18 | midA | increased number of autophagosomes |
DBS0350136 | midA-/ [act15]: GFP: tkt | midA | tkt-1 | tkt-2 | increased autophagy |
DBS0351180 | midA/ [act15]: midA(E200A) | midA | aberrant cellular homeostasis | decreased growth rate | decreased phototaxis |
DBS0351182 | midA/ [act15]: midA(G170V/ G172V) | midA | aberrant cellular homeostasis | decreased growth rate | decreased phototaxis |
DBS0351181 | midA/ [act15]: midA(N205A) | midA | aberrant cellular homeostasis | decreased growth rate | decreased phototaxis |
DG1020 | migA- | migA | abolished slug migration | decreased mound size | aberrant fruiting body morphogenesis | decreased fruiting body size |
DBS0350958 | migA- | migA | decreased gene expression | aberrant chemotaxis to cAMP |
DBS0350025 | mip1- | mip1-1 | mip1-2 | increased mound size | decreased chemotaxis to cAMP |
DBS0350027 | mip1-/ [act15]: mekA: FLAG | mekA | mip1-1 | mip1-2 | aberrant protein localization to cytoplasm |
DBS0266620 | mipp1- | mipp1 | aberrant inositol phosphate metabolic process | increased response to lithium |
DBS0309109 | mipp1-/ dpoA- | dpoA | mipp1 | aberrant inositol phosphate metabolic process | increased response to lithium |
DBS0236560 | mkcA- | mkcA | decreased prestalk gene expression |
DBS0236561 | mkcA-/ tagB- | mkcA | tagB | decreased sporulation |
DBS0236562 | mkcA-/ tagC- | mkcA | tagC | decreased sporulation |
DG1101 | mkcB- | mkcB | decreased fruiting body size |
DBS0236564 | mkkA- | mkkA | precocious culmination | decreased sorus size | increased stalk length |
DG1121 | mkpA- | mkpA | abolished aggregation |
DBS0236566 | mlcE- | mlcE | aberrant cytokinesis | decreased growth rate | delayed aggregation | aberrant taxis | aberrant sorocarp development | decreased cell motility | aberrant gene expression |
DBS0238058 | mlcE-/ [act15]: myc: mlcE | mlcE | wild type |
DBS0236567 | mlcR- | mlcR | aberrant cytokinesis | development arrests at mound stage | aberrant myosin II filament organization |
DBS0351550 | mlcR-/ [ecmAO]: GFP | mlcR | aberrant development of tipped mound |
HS183 | mlkA- | mlkA | aberrant cytokinesis |
DBS0349919 | mlkA-/ [act15]: GFP-mhcA | mlkA | aberrant stalk morphogenesis |
DG1033 | modA- | modA | decreased response to Gram-negative bacterium | abolished catalytic activity | aberrant fruiting body morphogenesis |
DBS0266903 | mpl1- | mpl1 | abolished stream development | decreased cell motility | decreased chemotaxis to cAMP | abolished aggregation |
DBS0266904 | mpl1-/ [act15]: flag: mpl1 | mpl1 | wild type |
DBS0349986 | mrfA- | mrfA | aberrant slug migration | delayed development |
DBS0350391 | mrfA-/ [act15]: myc: mrfA(K772A): FLAG | mrfA | aberrant protein modification |
DBS0350390 | mrfA-/ [act15]: myc: mrfA(S767A): FLAG | mrfA | aberrant protein modification | delayed development |
DBS0350389 | mrfA-/ [act15]: myc: mrfA: FLAG | mrfA | wild type |
DBS0349987 | mrfA-/ [emcA]: lacZ | mrfA | decreased prestalk A cell differentiation |
DBS0349988 | mrfA-/ dimB-/ [emcA]: lacZ | dimB | mrfA | decreased prestalk A cell differentiation |
DBS0350960 | mroh1- | mroh1 | aberrant exocytosis | decreased lysosome size |
DBS0236569 | mrps4- | mrps4 | delayed aggregation | aberrant fruiting body morphogenesis |
DBS0304881 | mrps4- | mrps4 | delayed aggregation |
DBS0351541 | mscS-/ mclN-/ pkd2- | mcln | mscS | pkd2 | aberrant calcium-mediated signaling |
DBS0304882 | mtDNA- | DidioMp05 | DidioMp21 | DidioMp26 | DidioMp27 | DidioMp30 | DidioMp35 | DidioMp36 | ai2a | ai2b | ai3 | ai4 | atp1 | atp4 | atp6 | atp8 | atp9 | cox1/ 2 | cox3 | cytB | mrpl11 | mrpl14 | mrpl16 | mrpl2 | mrpl6 | mrps12 | mrps13 | mrps14 | mrps19 | mrps2 | mrps4 | mrps7 | mrps8 | nad1 | nad11 | nad2 | nad3 | nad4 | nad4L | nad5 | nad6 | nad7 | nad9 | rnlA | abolished vegetative growth | abolished aggregation |
DBS0350868 | mtpn- | mtpn | decreased actin filament polymerization | decreased growth rate | decreased cell motility | aberrant stream morphology | decreased macropinocytosis |
HM1464 | mus81- | mus81 | wild type |
DBS0350866 | mvpA- | mvpA | aberrant cell morphology |
DBS0351489 | mvpA-/ mvpB- | mvpA | mvpB | decreased growth rate | aberrant cellular component organization |
DBS0236570 | mybB- | mybB | decreased gene expression | decreased activation of adenylate cyclase activity | decreased cGMP-mediated signaling | abolished aggregation |
DBS0236571 | mybB- | mybB | abolished aggregation |
HM388 | mybC- | mybC | decreased gene expression | development arrests at slug stage | decreased prespore gene expression | abolished culmination |
DBS0236572 | mybE- | mybE | increased migratory slug size | increased gene expression | abolished outer basal disc formation |
DBS0349993 | mybE-/ [btg]: lacZ | btg | mybE | increased gene expression |
DBS0237709 | mybE-/ [mrrA]: lacZ | mrrA | mybE | aberrant prestalk cell differentiation |
DBS0236573 | mybE-/ mybE: GFP | mybE | wild type | aberrant prestalk cell differentiation |
HDT1 | myoA- | myoA | aberrant aggregation | decreased lateral pseudopodium retraction | delayed aggregation | decreased cell motility | decreased chemotaxis rate | aberrant pseudopodium formation | decreased chemotaxis to cAMP |
HDT2 | myoA- | myoA | increased secretion of lysosomal enzymes | delayed aggregation |
HDT5 | myoA-/ myoB- | myoA | myoB | decreased pinocytosis | increased secretion of lysosomal enzymes | increased filopodium formation | aberrant aggregation | aberrant endosomal transport | decreased defense response to Gram-negative bacterium | aberrant cortical actin cytoskeleton organization | increased lateral pseudopodium formation | decreased growth rate | delayed aggregation | decreased cell motility | decreased fruiting body size | aberrant actin filament organization | decreased chemotaxis to cAMP | aberrant cytoskeleton organization |
DBS0350990 | myoA-/ myoB-/ [act15]: myoB | myoA | myoB | delayed aggregation |
DBS0350991 | myoA-/ myoB-/ [act15]: myoB(1-1057) | myoA | myoB | decreased pinocytosis | decreased growth rate | aberrant actin filament organization |
DBS0350992 | myoA-/ myoB-/ [act15]: myoB(S332) | myoA | myoB | decreased pinocytosis | decreased growth rate | aberrant actin filament organization |
DBS0351038 | myoA-/ myoF- | myoA | myoF | decreased lateral pseudopodium retraction | decreased cell motility | decreased chemotaxis to cAMP | aberrant cell morphology | abolished aggregation |
DBS0236579 | myoB- | myoB | increased secretion of lysosomal enzymes | aberrant aggregation | decreased lateral pseudopodium retraction | decreased cell motility | decreased chemotaxis to cAMP |
DBS0236580 | myoB- | myoB | increased lateral pseudopodium formation | decreased phagocytosis | delayed aggregation | decreased cell motility |
DBS0349853 | myoB- | myoB | decreased phagolysosome size | delayed phagosome reneutralization | aberrant phagosome maturation |
DBS0236583 | myoB-/ [AS]myoD | myoB | myoD | decreased pinocytosis | aberrant aggregation | decreased growth rate | decreased phagocytosis | decreased mound size | decreased cell motility |
DBS0236584 | myoB-/ [AS]myoD/ [KD]myoC | myoB | myoC | myoD | decreased pinocytosis | aberrant aggregation | decreased pinosome size | decreased growth rate | decreased phagocytosis | decreased mound size | decreased cell motility | increased number of pinosomes |
DBS0351378 | myoB-/ [act15]: GFP: myoB(1-720) | myoB | abolished protein localization to plasma membrane |
DBS0351379 | myoB-/ [act15]: GFP: myoB(1-800,813-1111) | myoB | abolished protein localization to actin wave | abolished protein localization to plasma membrane |
DBS0351380 | myoB-/ [act15]: GFP: myoB(713-1111) | myoB | abolished protein localization to leading edge |
DBS0351367 | myoB-/ [act15]: myoB(S332A) | myoB | abolished protein phosphorylation |
HDT6 | myoB-/ myoC- | myoB | myoC | increased secretion of lysosomal enzymes | decreased pinocytosis | increased filopodium formation | decreased growth rate | decreased cell motility | decreased fruiting body size | aberrant actin filament organization | aberrant cytoskeleton organization |
DBS0236585 | myoC- | myoC | decreased phagocytosis |
HDT4 | myoC- | myoC | decreased pinocytosis | decreased phagocytosis |
DBS0236587 | myoD- | myoD | wild type |
DBS0351031 | myoD-/ myoE- | myoD | myoE | decreased fruiting body size |
DBS0351034 | myoD-/ myoE-/ myoF- | myoD | myoE | myoF | decreased actin filament polymerization | aberrant engulfment during phagocytosis | decreased chemotaxis to cAMP | decreased fruiting body size |
DBS0351033 | myoD-/ myoF- | myoD | myoF | decreased fruiting body size |
DBS0351032 | myoE-/ myoF- | myoE | myoF | decreased fruiting body size |
HDT8 | myoF- | myoF | aberrant aggregation | wild type | increased lateral pseudopodium formation | decreased cell motility | decreased chemotaxis to cAMP | aberrant cell morphology |
DBS0350251 | myoG- | myoG | decreased protein localization to plasma membrane | decreased actin filament polymerization | abolished establishment of cell polarity | aberrant chemotaxis to cAMP | abolished aggregation |
DBS0236589 | myoI- | myoI | decreased spore germination |
DBS0236592 | myoI- | myoI | decreased cell-substrate adhesion | aberrant cytokinesis | decreased phagocytosis | aberrant cell morphology |
HDT15 | myoI- | myoI | decreased phagocytosis |
HDT17 | myoI- | myoI | decreased cell-cell adhesion | decreased protein level | decreased cell-substrate adhesion | decreased phagocytosis | decreased filopodium formation |
DBS0266889 | myoI-/ [act15]: GFP: myoI | myoI | wild type |
DBS0351400 | myoI-/ [act15]: GFP: myoI(1-1020) | myoI | abolished protein localization to pseudopodium | decreased filopodium formation |
DBS0351398 | myoI-/ [act15]: GFP: myoI(2057-2357) | myoI | increased filopodium formation |
DBS0266890 | myoI-/ [act15]: GFP: myoI(809-1154) | myoI | decreased phagocytosis |
DBS0351399 | myoI-/ [act15]: GFP: myoI(K23333A,K2336A) | myoI | increased filopodium formation |
DBS0237617 | myoI-/ [act15]: gbpD | gbpD | myoI | increased cell-substrate adhesion | aberrant cell morphology | increased pseudopodium formation |
HTD7 | myoJ- | myoJ | wild type |
DBS0350931 | myoJ- | myoJ | decreased hypotonic response | aberrant contractile vacuole discharge | aberrant contractile vacuole localization |
DBS0349844 | myoK- | myoK | aberrant cortical actin cytoskeleton organization | delayed aggregation | decreased phagocytosis | aberrant engulfment during phagocytosis | aberrant phagosome maturation | decreased chemotaxis rate | aberrant cell morphology | delayed phagosome acidification |
DBS0349846 | myoK-/ [act15]: YFP: myoK(1-121: 262-858) | myoK | decreased phagocytosis |
DBS0349850 | myoK-/ [act15]: myoK | myoK | increased phagocytosis |
DBS0349854 | myoK-/ [act15]: pakB(1-337: 563-852) | myoK | pakB | wild type |
DBS0236595 | myoM- | myoM | wild type |
DBS0351046 | nad2- | nad2 | decreased defense response to Gram-negative bacterium | decreased gene expression | decreased growth rate | aberrant fruiting body morphogenesis | aberrant phototaxis |
DBS0351048 | nad5- | nad5 | decreased defense response to Gram-negative bacterium | decreased gene expression | decreased growth rate | aberrant phototaxis |
AK1372 | nagB1- | nagB1 | decreased response to Gram-positive bacterium |
DBS0236596 | napA- | napA | aberrant cellular response to extracellular stimulus |
SB12 | napA- | napA | decreased cell-cell adhesion | decreased cell-substrate adhesion | decreased actin filament polymerization | decreased cell motility | decreased vegetative cell size | decreased establishment of cell polarity | decreased phototaxis |
DBS0351534 | napA-/ AX2 | napA | decreased protein level | increased membrane ruffling | aberrant cytokinesis | increased vegetative cell size | decreased cell motility |
SB14 | napA-/ pirA- | napA | pirA | decreased actin filament polymerization |
HC476 | ncsA- | ncsA | increased cAMP level | precocious gene expression | precocious development |
HC477 | ncsA- | ncsA | increased cAMP level | precocious gene expression | precocious development |
DBS0350297 | ncstn- | ncstn | aberrant culmination | abolished catalytic activity | decreased prespore cell differentiation |
DBS0350307 | ncstn- | ncstn | wild type | aberrant sorocarp development | decreased macropinocytosis |
DBS0350301 | ncstn-/ psenA- | ncstn | psenA | aberrant culmination | decreased prespore cell differentiation |
DBS0349947 | ndm- | ndm | aberrant chemotaxis | increased pinocytosis | decreased fruiting body size | aberrant pseudopodium formation |
DBS0349895 | ndrA- | ndrA | decreased engulfment during phagocytosis |
DBS0349896 | ndrA-/ [unk]: GFP: ndrA | ndrA | wild type |
DBS0350446 | ndrC- | ndrC | increased positive regulation of GTPase activity | increased number of centrosomes | aberrant cell separation during cytokinesis |
DBS0350121 | ndufaf5- | ndufaf5 | aberrant spore morphology | decreased growth rate | delayed development | aberrant phototaxis | decreased fruiting body size | decreased sporulation |
DBS0350125 | ndufaf5--/ [act15]: ndufaf5(G86V): GFP: TAP | ndufaf5 | decreased growth rate |
DBS0350126 | ndufaf5--/ [act15]: ndufaf5(L165F): GFP: TAP | ndufaf5 | decreased growth rate |
DBS0350127 | ndufaf5--/ [act15]: ndufaf5(L235P): GFP: TAP | ndufaf5 | decreased growth rate |
DBS0350124 | ndufaf5--/ [act15]: ndufaf5: GFP: TAP | ndufaf5 | wild type |
DBS0350122 | ndufaf5-/ [act15]: GFP: atg18 | atg18 | ndufaf5 | increased number of autophagosomes |
DBS0350134 | ndufaf5-/ [act15]: GFP: tkt | ndufaf5 | tkt-1 | tkt-2 | increased autophagy |
DBS0350137 | ndufaf5-/ [act15]: [AS]snfA | ndufaf5 | snfA | aberrant phototaxis |
DBS0304633 | nfaA- | nfaA | aberrant extracellular cAMP signaling pathway | aberrant activation of GTPase activity | increased actin filament polymerization | delayed aggregation | decreased cell motility | aberrant regulation of GTPase activity | aberrant regulation of protein kinase activity | aberrant protein localization to plasma membrane | decreased chemotaxis to cAMP | increased pseudopodium formation |
DBS0304634 | nfaA-/ rasG- | nfaA | rasG | decreased establishment of cell polarity |
DBS0351061 | ngap- | ngap | aberrant regulation of fruiting body formation | aberrant extracellular cAMP signaling pathway | aberrant adaptation of signaling pathway | increased actin filament polymerization | aberrant chemotaxis to cAMP | aberrant regulation of protein kinase activity | decreased establishment of cell polarity | increased activation of GTPase activity |
DBS0236604 | nhe1- | nhe1 | abolished cell motility in response to calcium ion | decreased intracellular pH | abolished establishment of cell polarity | decreased actin filament polymerization | decreased chemotaxis rate | delayed development | aberrant actin filament organization | decreased establishment of cell polarity | abolished chemotaxis to cAMP |
DBS0350003 | nhe1-/ [act15]: GFP: aip1 | aip1 | nhe1 | decreased establishment of cell polarity | decreased chemotaxis to cAMP |
DBS0350006 | nhe1-/ [act15]: GFP: aip1(E125A, E167A, F181A, F193A) | aip1 | nhe1 | abolished aggregation | abolished chemotaxis to cAMP |
DBS0350001 | nhe1-/ [act15]: aip1(168-597) | aip1 | nhe1 | delayed development |
DBS0350002 | nhe1-/ [act15]: aip1(383-597): FLAG | aip1 | nhe1 | decreased actin filament polymerization | abolished establishment of cell polarity | abolished chemotaxis to cAMP |
DBS0349841 | nhe1-/ [act15]: mhcA: GFP | mhcA | nhe1 | abolished protein localization to trailing edge |
DBS0236605 | nhe1-/ [act15]: nhe1: HA | nhe1 | wild type |
DBS0350508 | nlp- | nlp | wild type |
DBS0350509 | nlp-/ slp- | nlp | slp | decreased actin filament polymerization | aberrant organelle organization | abolished protein localization to cytoplasmic vesicle | decreased chemotaxis to cAMP |
DBS0351466 | nola4(I23T) | nola4 | decreased resistance to bleomycin | decreased growth rate | increased growth rate | aberrant response to oxidative stress |
DBS0351467 | nola4(T33M) | nola4 | decreased resistance to bleomycin | decreased gene expression | decreased growth rate | increased growth rate | aberrant response to oxidative stress |
DBS0236606 | nosA null (15-S-12) | nosA | development arrests at mound stage |
DBS0236607 | nosA null (2E4) | nosA | development arrests at mound stage |
DBS0235950 | nosA- | nosA | development arrests at mound stage | aberrant protein modification |
DBS0236941 | nosA-/ sonA- | nosA | sonA | wild type |
DBS0236608 | noxA- | noxA | abolished sporulation | aberrant sorocarp development |
DBS0236611 | noxA-/ [act15]: noxA: myc2 | noxA | aberrant fruiting body morphogenesis |
DBS0236610 | noxA-/ noxB | noxA | noxB | abolished sporulation | aberrant sorocarp development | decreased superoxide generation |
DBS0350768 | noxA-/ noxB-/ noxC- | noxA | noxB | noxC | aberrant defense response to bacterium |
DBS0236612 | noxB- | noxB | abolished sporulation | aberrant sorocarp development | decreased superoxide generation |
DBS0236613 | noxC- | noxC | abolished sporulation | aberrant sorocarp development |
DBS0238849 | npcA- | npcA | wild type |
HSB60 | nramp1- | nramp1 | decreased defense response to Gram-negative bacterium | decreased defense response to Gram-positive bacterium | abolished iron ion transport |
DBS0236696 | nramp1-/ [act15]: nramp1: GFP | nramp1 | increased defense response to Gram-negative bacterium |
DBS0236697 | nramp1-/ [act15]: nramp1: GFP | nramp1 | increased defense response to Gram-negative bacterium |
DBS0350092 | nrampB- | nrampB | decreased defense response to Gram-negative bacterium | delayed aggregation |
DBS0350093 | nrampB-/ nramp1- | nramp1 | nrampB | increased number of tip-organizers | decreased defense response to Gram-negative bacterium | delayed aggregation |
HM1060 | nsfA(A1847G, A1939T, T1977C, T2005G, A2025T, A2366T) | nsfA | decreased rate of endocytosis | decreased phagocytosis | abolished cell motility | decreased actin filament polymerization at leading edge |
HM1067 | nsfA(A1854T, T1984A, C2131A, A2398T, T2574A) | nsfA | decreased rate of endocytosis | abolished cell motility | decreased cell motility | aberrant hypotonic response | decreased actin filament polymerization at leading edge | increased phagocytosis |
DBS0236955 | nxnA- | nxnA | decreased lysosomal protein degradation | decreased culmination | decreased growth rate | delayed development | decreased chemotaxis to cAMP |
DBS0351164 | nxnA- | nxnA | aberrant cellular response to stress |
DBS0236702 | nxnA-/ [act15]: GFP: nxnB | nxnA | nxnB | development arrests at mound stage |
DBS0350857 | odc- | odc | aberrant cellular metabolic process | aberrant cell cycle | abolished vegetative growth |
DBS0236704 | osbA- | osbA | increased slug migration | precocious development |
DBS0238357 | p2xA- | p2xA | aberrant hypotonic response |
DBS0304487 | p2xA- | p2xA | wild type |
DBS0350312 | p2xA- | p2xA | aberrant contractile vacuole organization | abolished hypotonic response | decreased contractile vacuole size | aberrant regulation of GTPase activity |
DBS0350484 | p2xA-/ AX2 | p2xA | wild type | aberrant contractile vacuole discharge |
DBS0350485 | p2xA-/ AX4 | p2xA | aberrant contractile vacuole discharge | aberrant hypotonic response |
DBS0238362 | p2xA-/ [act15]: p2xA: GFP | p2xA | wild type |
DBS0350315 | p2xA-/ p2xA(K67A/ K289A) | p2xA | abolished hypotonic response |
DBS0350314 | p2xA-/ p2xA(R285K) | p2xA | decreased hypotonic response |
DBS0350313 | p2xA-/ p2xA(R63A) | p2xA | precocious hypotonic response |
DBS0306169 | p2xA-/ p2xB-/ p2xC-/ p2xD-/ p2xE- | p2xA | p2xB | p2xC | p2xD | p2xE | delayed hypotonic response | decreased growth rate |
DBS0306166 | p2xB- | p2xB | wild type |
DBS0306167 | p2xC- | p2xC | wild type |
DBS0306168 | p2xD- | p2xD | wild type |
DBS0304486 | p2xE- | p2xE | wild type |
DBS0304465 | padA(1-276) | padA | aberrant aggregation | decreased cell-cell adhesion | decreased gene expression | development arrests at slug stage | delayed aggregation | aberrant stalk cell differentiation | aberrant chemotaxis to cAMP | aberrant stream morphology | aberrant fruiting body morphogenesis | delayed development |
DBS0350013 | pah- | pah | abolished catalytic activity | abolished vegetative growth |
DBS0350014 | pah-/ [act15]: 6xHis: pah | pah | wild type |
DBS0350016 | pah-/ [act15]: 6xHis: pah(92-415) | pah | abolished vegetative growth |
DBS0350015 | pah-/ [act15]: 6xHis: pah(92-441) | pah | wild type |
DBS0236705 | pakA- | pakA | aberrant cytokinesis | delayed development | decreased myosin II assembly |
DBS0236706 | pakA- | pakA | wild type |
DBS0349885 | pakA- | pakA | delayed development | decreased chemotaxis to cAMP | increased bleb assembly |
DBS0236707 | pakA-/ [act15]: pakA | pakA | wild type |
DBS0350810 | pakA-/ [act15]: pakA(T579A) | pakA | decreased chemotaxis to cAMP |
DBS0349889 | pakA-/ [act15]: pakA: GFP | pakA | wild type |
DBS0236709 | pakB- | pakB | decreased growth rate | decreased bleb assembly |
DBS0236708 | pakB- | pakB | abolished establishment of cell polarity | decreased lateral pseudopodium retraction |
DBS0236712 | pakB-/ [act15]: GFP-pak(1-600) | pakB | abolished cytokinesis |
DBS0236710 | pakB-/ [act15]: GFP-pakB(1-337: 563-851) | pakB | abolished cytokinesis | increased pinocytosis | increased phagocytosis |
DBS0350428 | pakB-/ [act15]: RFP: abpE | abpE-1 | abpE-2 | pakB | decreased chemotaxis to cAMP | aberrant establishment or maintenance of cell polarity | abolished aggregation | abolished protein localization to leading edge |
DBS0350430 | pakB-/ [act15]: RFP: abpE/ [act15]: GFP: pak(1-180) | abpE-1 | abpE-2 | pakB | wild type |
DBS0236715 | pakB-/ pakC- | pakB | pakC | decreased chemotaxis rate |
DBS0236717 | pakC(K121H/ E124L) | pakC | abolished protein binding |
DBS0236719 | pakC(R34C) | pakC | decreased lateral pseudopodium retraction | decreased chemotaxis rate |
DBS0236720 | pakC(S466A/ P470A) | pakC | decreased lateral pseudopodium retraction | decreased chemotaxis rate |
DBS0236716 | pakC- | pakC | decreased lateral pseudopodium retraction | decreased bleb assembly | decreased chemotaxis rate |
DBS0350281 | pakD- | pakD | aberrant cellular homeostasis | aberrant filopodium formation | aberrant actin cytoskeleton organization | abolished negative regulation of vegetative growth | abolished aggregation | aberrant actin filament polymerization | aberrant establishment or maintenance of cell polarity | decreased chemotaxis to cAMP | increased growth rate | aberrant cellular response to extracellular stimulus | abolished positive regulation of chemorepellant activity |
DBS0350282 | pakD-/ [act15]: pakD | pakD | development arrests at mound stage |
DBS0350395 | pakD-/ [act15]: pakD: GFP | pakD | wild type |
HC392 | patB- | patB | abolished vegetative growth |
DBS0236726 | pats1- | pats1 | aberrant cytokinesis |
DBS0350097 | pats1- | pats1 | aberrant cytokinesis |
LAS45 | pats1- | pats1 | decreased socially cooperative development |
DBS0236727 | pats1-/ [act15]: GFP: pats1(2087-2351) | pats1 | aberrant cytokinesis |
DBS0236728 | paxB- | paxB | decreased exocytosis | decreased cell-substrate adhesion | abolished slug migration | increased chemotaxis to cAMP | development arrests at mound stage | decreased prespore gene expression | aberrant fruiting body morphogenesis | decreased cell migration to prestalk region | increased phagocytosis |
DBS0304926 | paxB- | paxB | aberrant cell separation during cytokinesis | decreased cell-substrate adhesion | aberrant cytokinesis | decreased cell motility |
DBS0304930 | paxB-/ [act15]: GFP: paxB | paxB | wild type |
DBS0350973 | paxB-/ [act15]: gpaH | gpaH | paxB | aberrant cytokinesis |
DBS0350094 | paxB-/ [act15]: pldB | paxB | pldB | wild type | increased phagocytosis |
DBS0236730 | paxB-/ [ecmA]: paxB: GFP | paxB | decreased cell migration to prestalk region |
DBS0236732 | paxB-/ [pspA]: paxB: GFP | paxB | decreased cell migration to prestalk region |
DBS0304929 | paxB-/ mhcA- | mhcA | paxB | aberrant cytokinesis |
DBS0236733 | pcp- | pcp | wild type | aberrant hypotonic response |
DBS0236734 | pde4- | pde4 | decreased culmination | abolished stream development | delayed slug development | increased number of early culminant tips | increased protein level | delayed culmination |
DBS0236735 | pde4-/ [act15]: pde4: GFP | pde4 | wild type |
DBS0235991 | pdeD- | pdeD | decreased 3',5'-cyclic-GMP phosphodiesterase activity |
DBS0236736 | pdeD- | pdeD | aberrant calcium-mediated signaling |
DBS0350517 | pdeD- | pdeD | decreased 3',5'-cyclic-GMP phosphodiesterase activity | increased fruiting body size | aberrant stream morphology |
DBS0351194 | pdeD- | pdeD | decreased protein localization to cell cortex | abolished protein localization to cell cortex | aberrant chemotaxis to cAMP | aberrant actin filament polymerization | decreased myosin II assembly | increased activation of GTPase activity |
DBS0350518 | pdeD-/ [act15]: pdeD: YFP | pdeD | wild type |
DBS0235992 | pdeD-/ pdeE- | pdeD | pdeE | decreased protein localization to cell cortex | decreased 3',5'-cyclic-GMP phosphodiesterase activity | decreased 3',5'-cyclic-AMP phosphodiesterase activity | decreased lateral pseudopodium formation | increased protein kinase activation |
DBS0350893 | pdeD-/ pdeE-/ [unk]: pdeE | pdeD | pdeE | delayed aggregation |
DBS0350900 | pdeE- | pdeE | increased oscillatory cAMP signaling | abolished 3',5'-cyclic-AMP phosphodiesterase activity |
DBS0235993 | pdeE- | pdeE | decreased 3',5'-cyclic-AMP phosphodiesterase activity | aberrant chemotaxis to cAMP |
DBS0236740 | pdiA- | pdiA | decreased mound size | aberrant oscillatory cAMP signaling | decreased fruiting body size |
DBS0350797 | pdkA- | pdkA | aberrant macropinocytosis | decreased protein kinase activation |
DBS0350817 | pdkA- | pdkA | decreased mound size | decreased protein kinase activation |
DBS0350799 | pdkA-/ pdkB- | pdkA | pdkB | aberrant chemotaxis to cAMP | development arrests at mound stage | decreased protein kinase activation | decreased establishment of cell polarity |
DBS0350819 | pdkA-/ pdkB- | pdkA | pdkB | aberrant sorocarp development |
DBS0350798 | pdkB- | pdkB | increased macropinocytosis |
DBS0350818 | pdkB- | pdkB | decreased mound size |
DBS0237029 | pdsA- | pdsA | aberrant chemotaxis to cAMP | aberrant stream morphology |
UK7 | pdsA- | pdsA | decreased 3',5'-cyclic-AMP phosphodiesterase activity | decreased gene expression | aberrant sorocarp development | abolished aggregation |
HPX235 | pdsA- | pdsA | abolished catalytic activity | abolished aggregation |
DBS0236741 | pefA- | pefA | wild type |
DBS0236742 | pefA-/ pefB- | pefA | pefB | wild type |
DBS0236744 | pefB- | pefB | wild type |
DBS0236745 | pefB-/ cybA- | cybA | pefB | wild type |
DBS0236746 | pefB-/ noxA- | noxA | pefB | wild type |
DBS0236747 | pefB-/ noxA-/ [act15]: pefB | noxA | pefB | aberrant sorocarp development |
DBS0236748 | pefB-/ noxB- | noxB | pefB | wild type |
DBS0236749 | pefB-/ noxC- | noxC | pefB | abolished sporulation | aberrant sorocarp development |
HW260 | pgtA- | pgtA | increased vegetative cell size |
DBS0305022 | pgtB- | pgtB | aberrant cellular metabolic process | aberrant spore coat morphology | aberrant hyperosmotic response |
DBS0305024 | pgtB-/ pgtC- | pgtB | pgtC | aberrant cellular metabolic process | aberrant spore coat morphology | aberrant hyperosmotic response |
DBS0305023 | pgtC- | pgtC | aberrant cellular metabolic process | aberrant hyperosmotic response |
DBS0236752 | phdA- | phdA | decreased actin filament polymerization | decreased mound size | decreased chemotaxis rate | decreased fruiting body size |
DBS0236753 | phdA-/ [act15]: phdA | phdA | wild type |
DBS0236754 | phdA-/ [act15]: phdA: GFP | phdA | wild type |
DBS0350865 | phdG- | phdG | decreased chemotaxis to cAMP |
DBS0236755 | phg1A- | phg1A | increased secretion of lysosomal enzymes | decreased lysosomal protein degradation | decreased protein level | decreased cell-substrate adhesion | decreased gene expression | aberrant defense response to bacterium | aberrant cytokinesis | decreased phagocytosis | abolished defense response to bacterium | decreased growth rate | development arrests at slug stage | decreased protein localization to cell surface | aberrant phagocytosis | increased lysosomal pH | decreased protein stabilization |
DBS0351549 | phg1A- | phg1A | decreased cell-substrate adhesion | decreased phagocytosis |
DBS0236757 | phg1A-/ [act15]: kil1 | kil1 | phg1A | decreased lysosomal protein degradation | increased secretion of lysosomal enzymes | wild type | increased lysosomal pH | decreased protein stabilization |
DBS0304869 | phg1A-/ [act15]: phg1A(1-276): phg1B221-587) | phg1A | phg1B | decreased phagocytosis |
DBS0304868 | phg1A-/ [act15]: phg1B | phg1A | phg1B | increased secretion of lysosomal enzymes | wild type | decreased cell-substrate adhesion | aberrant protein level | decreased phagocytosis |
DBS0304870 | phg1A-/ [act15]: phg1B(1-220): phg1a(277-642) | phg1A | phg1B | decreased phagocytosis |
DBS0304872 | phg1A-/ phg1B- | phg1A | phg1B | increased secretion of lysosomal enzymes | decreased cell-substrate adhesion | decreased phagocytosis | decreased growth rate | development arrests at tipped mound stage | abolished culmination |
DBS0304866 | phg1B- | phg1B | increased secretion of lysosomal enzymes | decreased protein level | decreased phagocytosis | decreased growth rate | abolished culmination |
DBS0236758 | phg2- | phg2 | decreased cell-substrate adhesion | decreased phagocytosis | aberrant cytokinesis | decreased cell motility | aberrant cell morphology | aberrant actin filament organization | precocious development | precocious gene expression | aberrant response to nutrient |
DBS0238400 | phg2- | phg2 | increased filopodium formation | increased actin filament polymerization | increased cell-substrate adhesion | decreased chemotaxis to cAMP | aberrant cell morphology | increased phagocytosis |
DBS0350578 | phg2- | phg2 | abolished gene expression | decreased protein phosphorylation | aberrant protein localization to nucleus |
DBS0236760 | phg2-/ [act15]: GFP: phg2(199-1389) | phg2 | decreased phagocytosis |
DBS0237615 | phg2-/ [act15]: gbpD | gbpD | phg2 | aberrant cell morphology | abolished chemotaxis to cAMP | increased pseudopodium formation |
DBS0350580 | phg2-/ [act15]: myc: ptpC | phg2 | ptpC | abolished protein phosphorylation |
HG1648 | phgA- | phgA | increased contractile vacuole size | aberrant contractile vacuole organization | aberrant hypotonic response | aberrant pore formation during contractile vacuole discharge |
DBS0302610 | phgA-/ [OE]: dsgg | dsgg | phgA | aberrant contractile vacuole organization |
DBS0236761 | phgA-/ lvsA-/ [act6]: GFP: lvsA | lvsA | phgA | aberrant protein localization to contractile vacuole |
DBS0236762 | phlp1- | phlp1 | decreased response to cAMP | aberrant regulation of protein modification | abolished chemotaxis to folate | decreased growth rate | abolished protein localization to plasma membrane | decreased cGMP-mediated signaling | abolished aggregation | abolished chemotaxis to cAMP |
DBS0236763 | phlp1-/ [OE]: phpl1 | phlp1 | wild type |
DBS0236764 | phlp3- | phlp3 | wild type |
DBS0350824 | phr- | phr | aberrant chemotaxis to cAMP | delayed development |
HW288 | phyA- | phyA | abolished sporulation | abolished stalk development | abolished peptidyl-proline hydroxylation | abolished culmination | increased response to hypoxia |
DBS0266771 | phyA-/ [ecmA]: phyA(D132N): myc | phyA | decreased peptidyl-proline hydroxylation |
DBS0266770 | phyA-/ [ecmA]: phyA(R276A): myc | phyA | abolished peptidyl-proline hydroxylation | abolished culmination |
piaA(G917D) | piaA | ||
DBS0236769 | piaA(G917D)/ [act15]: piaA | piaA | delayed aggregation |
DBS0351455 | piaA(G917D)/ [unk]: GFP: piaA(G963E) | piaA | abolished aggregation |
DBS0350882 | piaA(G917D)/ acrA- | acrA | piaA | abolished gene expression | abolished establishment of cell polarity | abolished chemotaxis to cAMP |
DBS0350877 | piaA(G917D)/ hephA- | hephA | piaA | increased response to cAMP | wild type | abolished activation of adenylate cyclase activity | decreased cAMP level |
DBS0236767 | piaA- | piaA | aberrant activation of adenylate cyclase activity |
DBS0236770 | piaA- | piaA | aberrant cytokinesis |
DBS0236771 | piaA- | piaA | abolished aggregation | decreased myosin II assembly | increased phagocytosis |
DBS0304637 | piaA- | piaA | decreased cell motility | decreased chemotaxis rate | decreased establishment of cell polarity | aberrant protein tyrosine phosphorylation |
DBS0351319 | piaA- | piaA | decreased taxis |
DBS0349879 | piaA- | piaA | decreased protein phosphorylation | decreased protein kinase activity | abolished protein phosphorylation | decreased chemotaxis to cAMP | aberrant protein localization to plasma membrane | increased activation of GTPase activity | abolished positive regulation of chemorepellant activity |
DBS0351403 | piaA- | piaA | aberrant cytokinesis |
DBS0236779 | pik6- | pik6 | decreased gene expression | abolished aggregation |
DBS0236772 | pikA- | pikA | wild type |
DBS0236766 | pikA-/ pikB- | pikA | pikB | aberrant negative chemotaxis | decreased response to bacterium | decreased actin filament polymerization | decreased activation of GTPase activity | abolished protein localization to plasma membrane | aberrant chemotaxis to cAMP | decreased cell motility | abolished protein kinase activation | abolished protein localization to trailing edge | decreased chemotaxis to folate | decreased chemotaxis to cAMP | decreased myosin II assembly |
DBS0236773 | pikA-/ pikB- | pikA | pikB | abolished stream development | decreased pinocytosis | aberrant aggregation | decreased exocytosis | aberrant activation of adenylate cyclase activity | aberrant macropinocytosis | abolished protein localization to plasma membrane | delayed aggregation | decreased spore cell differentiation | increased cAMP level | abolished vegetative growth | aberrant sorocarp development | aberrant phagolysosome formation | aberrant phagosome maturation | decreased phosphatidylinositol biosynthesis | aberrant fruiting body morphogenesis | aberrant actin filament organization | aberrant cell morphology |
HM1141 | pikA-/ pikB- | pikA | pikB | decreased pinocytosis | decreased growth rate | decreased cell motility | decreased taxis |
DBS0350471 | pikA-/ pikB-/ [act15]: GFP: cap | cap | pikA | pikB | wild type |
DBS0252703 | pikA-/ pikB-/ pikC- | pikA | pikB | pikC | decreased protein localization to leading edge | increased cell motility |
HM1200 | pikA-/ pikB-/ pikC-/ pikF-/ pikG- | pikA | pikB | pikC | pikF | pikG | aberrant aggregation | decreased pinocytosis | decreased protein tyrosine phosphorylation | increased chemotaxis to folate | aberrant macropinocytosis | decreased growth rate | decreased phagocytosis | decreased cell motility | increased bleb assembly | decreased chemotaxis to cAMP | aberrant protein localization to plasma membrane | aberrant signal transduction |
HM1284 | pikA-/ pikB-/ pikC-/ pikF-/ pikG-/ pikH- | pikA | pikB | pikC | pikF | pikG | pikH | decreased defense response to Gram-negative bacterium | decreased cell motility |
HM1295 | pikA-/ pikB-/ pikC-/ pikF-/ pikG-/ pten- | pikA | pikB | pikC | pikF | pikG | pten | aberrant aggregation | decreased defense response to Gram-negative bacterium | decreased growth rate | decreased cell motility | increased resistance to N-Phenylthiourea |
DBS0238073 | pikA-/ pikB-/ plaA- | pikA | pikB | plaA | decreased actin filament polymerization | delayed aggregation | aberrant chemotaxis to cAMP | abolished positive chemotaxis |
DBS0236774 | pikB- | pikB | wild type |
DBS0236776 | pikC- | pikC | wild type |
DBS0236777 | pikD1 | pikD | abolished slug migration | delayed aggregation | decreased mound size | aberrant fruiting body morphogenesis | decreased sporulation |
DBS0236778 | pikE- | pikE | wild type |
HM1241 | pikF- | pikF | decreased pinocytosis | decreased growth rate | aberrant pinosome maturation |
LAS31 | pikG- | pikG | aberrant socially cooperative development |
HM1513 | pikI- | pikI | decreased catalytic activity | decreased actin filament polymerization | decreased growth rate | aberrant chemotaxis to cAMP | decreased cGMP-mediated signaling | aberrant calcium-mediated signaling | decreased protein kinase activation | increased bleb assembly |
DBS0350828 | pinA-/ [ecmAO]: lacZ | pinA | aberrant prestalk cell differentiation |
DBS0350827 | pinA-/ [pspA]: lacZ | pinA | aberrant prespore cell differentiation |
DBS0351429 | pip5k3-/ AX2 | pip5k3 | decreased defense response to Gram-negative bacterium | aberrant defense response to bacterium | aberrant phagosome maturation | decreased protein processing in phagocytic vesicle | decreased protein localization to phagocytic vesicle |
DBS0351428 | pip5k3-/ AX3 | pip5k3 | aberrant macropinocytosis | decreased growth rate |
SB16 | pirA- | pirA | decreased vegetative cell size | increased cell motility |
SB3 | pirA- | pirA | increased actin filament polymerization | increased vegetative cell size | decreased cell motility | aberrant cellular response to stress | increased pseudopodium formation |
DBS0351205 | pirA- | pirA | decreased cell motility | aberrant pseudopodium formation | abolished protein level |
DBS0351533 | pirA-/ AX2 | pirA | decreased protein level | aberrant macropinocytosis | aberrant cytokinesis | increased vegetative cell size | decreased cell motility | decreased pseudopodium formation | increased bleb assembly | decreased filopodium formation |
DBS0351206 | pirA-/ pirA(K193D/ R194D): EGFP | pirA | abolished protein localization to cell periphery | decreased protein phosphorylation |
DBS0349901 | pisA- | pisA | increased gene expression | precocious development | decreased fruiting body size | aberrant prestalk cell differentiation |
DBS0236783 | pkaC- | pkaC | abolished gene expression | increased protein phosphorylation | aberrant response to abiotic stimulus | decreased protein level | decreased gene expression | decreased activation of GTPase activity | abolished catalytic activity | aberrant response to cAMP | increased cellular thermotolerance | aberrant myosin II filament organization | decreased protein kinase activation | abolished aggregation | aberrant actin filament organization | aberrant protein localization to plasma membrane | aberrant protein localization to cell cortex | abolished chemotaxis to cAMP | increased protein kinase activation | increased activation of GTPase activity | abolished positive regulation of chemorepellant activity |
DBS0350694 | pkaC-/ [act15]: pkaC | pkaC | abolished culmination |
DBS0350708 | pkaC-/ [act6]: pkaC(303-648) | pkaC | wild type |
DBS0350707 | pkaC-/ [act6]: pkaC(330-648) | pkaC | abolished aggregation |
DBS0350710 | pkaC-/ [dscC]: LUC | pkaC | decreased gene expression | increased macropinocytosis |
DBS0236782 | pkaC-/ gdt1- | gdt1 | pkaC | increased gene expression | abolished aggregation |
HTY217 | pkaR(A31T) | pkaR | abolished protein kinase activation | precocious development |
DBS0235411 | pkaR- | pkaR | abolished stream development | increased resistance to valproic acid | decreased spore germination | aberrant extracellular cAMP signaling pathway | aberrant response to lithium | increased gene expression | precocious sporulation | increased lateral pseudopodium formation | aberrant chemotaxis to cAMP | decreased cell motility | decreased fruiting body size | aberrant cell morphology |
DBS0351315 | pkbA- | pkbA | decreased macropinocytosis |
DBS0236784 | pkbA- | pkbA | decreased pinocytosis | decreased protein phosphorylation | aberrant macropinocytosis | decreased bleb assembly | abolished protein kinase activation | abolished protein localization | abolished protein localization to trailing edge | aberrant phagosome maturation | increased phagocytosis | decreased myosin II assembly |
DBS0349876 | pkbA- | pkbA | aberrant cellular response to extracellular stimulus | increased protein kinase activation |
DBS0350113 | pkbA-/ [act15]: GFP: rheb(Q64L) | pkbA | rheb | decreased phagocytosis |
DBS0236785 | pkbA-/ pkgB- | pkbA | pkgB | aberrant chemotaxis to cAMP | abolished vegetative growth | decreased chemotaxis rate | abolished protein phosphorylation | abolished aggregation | aberrant cellular response to extracellular stimulus | increased activation of GTPase activity | increased protein kinase activation |
DBS0304640 | pkbA-/ pkgB- | pkbA | pkgB | aberrant cell motility | abolished vegetative growth |
DBS0351317 | pkbA-/ pkgB- | pkbA | pkgB | aberrant macropinocytosis | abolished vegetative growth | abolished macropinocytosis |
DBS0350916 | pkcA- | pkcA | decreased cell-cell adhesion | decreased protein level | increased chemotaxis to cAMP | decreased gene expression | increased number of mound tips | increased actin filament polymerization | aberrant oscillatory cAMP signaling | decreased fruiting body size | abolished positive regulation of chemorepellant activity |
DBS0350918 | pkcA- | pkcA | aberrant aggregation | decreased catalytic activity | aberrant cytokinesis | aberrant sorocarp development |
DBS0350919 | pkcA-/ [act15]: pldB | pkcA | pldB | aberrant aggregation | decreased sporulation |
DBS0350917 | pkcA-/ [ecmA]: GFP | pkcA | aberrant prestalk gene expression |
DBS0350475 | pkd2- | pkd2 | increased resistance to naringenin | decreased growth rate |
DBS0350367 | pkd2- | pkd2 | aberrant cellular response to fluid shear stress | aberrant exocytosis |
DBS0351540 | pkd2-/ AX2 | pkd2 | aberrant calcium-mediated signaling |
DBS0351542 | pkd2-/ iplA- | iplA | pkd2 | aberrant calcium-mediated signaling |
DBS0236786 | pkgB- | pkgB | decreased protein phosphorylation | development arrests at mound stage | abolished spore cell differentiation |
DBS0350328 | pkgB- | pkgB | aberrant sorocarp development |
DBS0351316 | pkgB- | pkgB | decreased macropinocytosis |
DBS0304638 | pkgB- | pkgB | decreased cell-substrate adhesion | development arrests at mound stage | decreased chemotaxis rate | decreased taxis | increased cell motility | increased bleb assembly |
DBS0236787 | pkgB-/ [act15]: pkbA | pkbA | pkgB | wild type |
DBS0236789 | pkgB-/ [act15]: pkgB(K182M) | pkgB | development arrests at mound stage |
DBS0350329 | pkgB-/ [emcB]: lacZ | pkgB | abolished prestalk gene expression |
DBS0236790 | pkgB-/ [gbfA]: pkbA | pkbA | pkgB | wild type |
DBS0236791 | pkgB-/ [gbfA]: pkgB | pkgB | wild type |
DBS0350319 | pks17- | pks17 | decreased fatty acid level | increased gene expression | delayed development | decreased fruiting body size |
LAS44 | pks2- | pks2 | decreased socially cooperative development |
LAS19 | pks26- | pks26 | aberrant socially cooperative development |
DBS0238068 | plaA- | plaA | aberrant chemotaxis to cAMP | abolished aggregation | abolished positive regulation of chemorepellant activity |
DBS0238067 | plaA- | plaA | abolished aggregation |
DBS0306196 | plaA- | plaA | aberrant chemotaxis to cAMP | decreased bleb assembly | decreased necrotic cell death |
DBS0350831 | plaA-/ piaA- | piaA | plaA | decreased taxis | decreased chemotaxis to cAMP | aberrant actin filament organization |
DBS0350486 | plaA-/ sgcA- | plaA | sgcA | aberrant chemotaxis to cAMP |
DBS0350487 | plaA-/ sgcA-/ pkgB- | pkgB | plaA | sgcA | aberrant chemotaxis to cAMP |
DG1067 | plbG- | plbG | decreased stalk width | decreased stalk length |
HAD236 | plc- | plc | decreased protein localization to plasma membrane | aberrant chemotaxis to cAMP | decreased protein localization to cytoplasm | decreased protein kinase activation | abolished aggregation |
HD1.19 | plc- | plc | aberrant negative chemotaxis |
HD10 | plc- | plc | aberrant cellular homeostasis | wild type | aberrant spore germination |
DBS0267125 | plc-/ [OE]: dagA(PH): GFP/ [OE]: plc | dagA | plc | increased protein localization to plasma membrane | decreased chemotaxis to cAMP |
DBS0350047 | plc-/ [act15]: pten: GFP | plc | pten | wild type | aberrant protein localization to cytoplasm |
DBS0236796 | pldB- | pldB | decreased catalytic activity | precocious aggregation |
DBS0236797 | pldB-/ [act15]: pldB: GFP | pldB | abolished aggregation |
DBS0350604 | pldB-/ [unk]: GFP | pldB | increased cell migration to prestalk region |
DBS0350605 | pldB-/ [unk]: lacZ | pldB | increased cell migration to prestalk region |
DBS0236799 | plip- | plip | delayed aggregation |
DBS0351187 | plnA- | plnA | aberrant defense response to bacterium |
DBS0350007 | png- | png | delayed aggregation | decreased mound size | aberrant fruiting body morphogenesis |
DBS0350492 | png-/ [ecmAO]: lacZ | png | aberrant prestalk cell differentiation |
DBS0350491 | png-/ [ecmA]: lacZ | png | aberrant prestalk A cell differentiation |
DBS0350493 | png-/ [pspA]: lacZ | png | decreased prespore cell differentiation |
DBS0236820 | ponA- | ponA | precocious aggregation | decreased actin nucleation | aberrant sorocarp development | aberrant pseudopodium formation |
DBS0236821 | ponA- | ponA | precocious aggregation | decreased actin nucleation | aberrant sorocarp development | aberrant pseudopodium formation |
DG1057 | potA- | potA | aberrant fruiting body morphogenesis |
DBS0351064 | poxA- | poxA | aberrant defense response to bacterium |
DBS0236824 | ppk1- | ppk1 | decreased growth rate | decreased phagocytosis | decreased fruiting body size | delayed culmination | decreased sporulation |
ASH01 | ppk1- | ppk1 | aberrant cellular homeostasis | decreased ATP level | decreased growth rate | aberrant spore germination | aberrant macromolecule biosynthesis | decreased fruiting body size | increased growth rate |
DBS0351356 | ppk1-/ [act15]: GFP: hsp48 | hsp48 | ppk1 | decreased protein level |
DBS0236825 | ppk1-/ [act15]: ppk1 | ppk1 | wild type |
DBS0238099 | ppp4C- | ppp4c | development arrests at mound stage | delayed development |
DBS0238110 | ppp4C-/ [act15]: smkA | ppp4c | smkA | development arrests at mound stage | delayed development |
DBS0238033 | proC- | proC | increased lateral pseudopodium formation | decreased chemotaxis rate | decreased establishment of cell polarity |
DBS0238034 | proC-/ [unk]: FLAG: proC | proC | wild type |
DBS0266716 | pscA- | pscA | wild type |
DBS0266803 | psenA- | psenA | aberrant culmination | decreased prespore cell differentiation |
DBS0350302 | psenA- | psenA | decreased prespore cell differentiation | aberrant calcium-mediated signaling |
DBS0350304 | psenA-/ psenB- | psenA | psenB | increased gene expression | abolished prespore cell differentiation | development arrests at mound stage | increased protein modification | decreased phagocytosis | aberrant calcium-mediated signaling | increased cAMP level | aberrant sorocarp development | decreased macropinocytosis | aberrant phagosome maturation | decreased protein processing in phagocytic vesicle | decreased prestalk gene expression | decreased stalk cell differentiation |
DBS0350305 | psenA-/ psenB-/ [act15]: GFP: psenB | psenA | psenB | wild type |
DBS0350306 | psenA-/ psenB-/ [act15]: psenB(D348A/ D394A) | psenA | psenB | wild type |
DBS0350295 | psenB- | psenB | decreased phagocytosis | abolished catalytic activity |
DBS0350303 | psenB- | psenB | decreased prespore cell differentiation | aberrant calcium-mediated signaling |
DBS0351095 | psenB- | psenB | aberrant response to chemical |
DBS0350298 | psenB-/ psenA- | psenA | psenB | aberrant culmination | decreased phagocytosis | abolished catalytic activity | decreased prespore cell differentiation |
HOK2 | psiA- | psiA | abolished prespore cell division |
DBS0351581 | psiA-/ [ecmB]: lacZ | psiA | precocious prestalk gene expression |
DBS0351578 | psiA-/ [rnrB]: lacZ | psiA | aberrant prespore gene expression |
DBS0236021 | psiM- | psiM | wild type |
DBS0236022 | psiM- | psiM | wild type |
DBS0236828 | pslA- | pslA | abolished sporulation | increased mound size | decreased sorus size | aberrant prestalk gene expression | increased stalk length | abolished stalk cell differentiation | abolished prespore gene expression |
DBS0236829 | psmC1- | psmC1 | increased resistance to spectinomycin | aberrant standing slug morphology | abolished slug migration | increased vegetative cell size |
HW70 | pspB- | pspB | aberrant spore coat morphology | precocious spore germination |
DBS0302352 | psrA- | psrA | decreased culmination | increased protein phosphorylation | decreased activation of GTPase activity | delayed prestalk gene expression | decreased cell motility | delayed development | increased protein kinase activation |
DBS0351094 | psrA- | psrA | aberrant response to chemical |
DBS0302356 | psrA-/ [act15]: FLAG: gskA | gskA | psrA | increased protein kinase activation |
DBS0302353 | psrA-/ [act15]: ecmA: lacZ | psrA | aberrant prestalk gene expression |
DBS0302354 | psrA-/ [act15]: ecmB: lacZ | psrA | aberrant prestalk gene expression |
DBS0302357 | psrA-/ [act15]: gskA(K84M/ K85M) | gskA | psrA | decreased culmination | decreased prespore gene expression | delayed development | increased protein kinase activation |
DBS0302355 | psrA-/ [act15]: psrA | psrA | wild type |
DBS0350829 | psrA-/ [unk]: FLAG: rasD(G12T) | psrA | rasD | increased protein kinase activation |
HM1289 | pten- | pten | aberrant cell motility | decreased lateral pseudopodium retraction | decreased cell motility | decreased macropinocytosis | abolished aggregation | decreased chemotaxis to cAMP |
DBS0236830 | pten- | pten | decreased response to Gram-negative bacterium | decreased positive regulation of GTPase activity | decreased actin filament polymerization | decreased lateral pseudopodium retraction | abolished protein localization to plasma membrane | decreased growth rate | increased actin filament polymerization | decreased phagocytosis | decreased bleb assembly | decreased cell motility | increased protein localization to plasma membrane | decreased chemotaxis to cAMP | abolished aggregation | aberrant pseudopodium formation | increased pseudopodium formation | aberrant signal transduction | abolished positive regulation of chemorepellant activity |
DBS0349884 | pten- | pten | aberrant cytokinesis | increased protein kinase activity | decreased chemotaxis to cAMP | decreased establishment of cell polarity |
DBS0350660 | pten- | pten | decreased uropod retraction | decreased protein localization to cleavage furrow | decreased growth rate | aberrant cytokinesis | decreased protein localization to pseudopodium |
DBS0350454 | pten-/ [act15]: lpten: RFP | lpten | pten | wild type |
DBS0349890 | pten-/ [act15]: pakA: GFP | pakA | pten | aberrant cytokinesis |
DBS0350754 | pten-/ [act15]: pten(186-515): GFP | pten | aberrant sorocarp development | decreased chemotaxis to cAMP |
DBS0350755 | pten-/ [act15]: pten(C124S): GFP | pten | aberrant sorocarp development | decreased chemotaxis to cAMP |
DBS0351587 | pten-/ [act15]: pten(G129E) | pten | increased lateral pseudopodium formation | aberrant localization |
DBS0236831 | pten-/ [act15]: pten: GFP | pten | wild type |
DBS0349888 | pten-/ gefS- | gefS | pten | aberrant cytokinesis | decreased chemotaxis to cAMP |
DBS0349891 | pten-/ pakA- | pakA | pten | decreased chemotaxis to cAMP |
DBS0349893 | pten-/ pakA-/ [act15]: pakA(T585A): GFP | pakA | pten | decreased chemotaxis to cAMP |
DBS0349900 | pten-/ pakA-/ [act15]: pakA(T585E): GFP | pakA | pten | aberrant cytokinesis | decreased chemotaxis to cAMP |
DBS0349899 | pten-/ pakA-/ [act15]: pakA: GFP | pakA | pten | aberrant cytokinesis |
DBS0349887 | pten-/ piaA- | piaA | pten | decreased protein kinase activity | decreased chemotaxis to cAMP |
DBS0349880 | pten-/ pkbA- | pkbA | pten | decreased chemotaxis to cAMP |
DBS0349886 | pten-/ pkgB- | pkgB | pten | aberrant cytokinesis | increased protein kinase activation |
DBS0236832 | ptpA1- | ptpA1-1 | ptpA1-2 | decreased prespore cell differentiation | precocious development | increased prestalk O cell differentiation |
DBS0236833 | ptpB- | ptpB | increased migratory slug size |
DBS0350675 | ptpB-/ [act15]: 6xHis: erkA | erkA | ptpB | aberrant stream morphology |
DBS0236834 | ptpC+/ - | ptpC | aberrant cytokinesis | decreased growth rate |
DBS0236835 | pufA- | pufA | increased protein kinase activity | aberrant fruiting body morphogenesis | increased protein level | precocious development |
DBS0304391 | pyk3- | pyk3 | increased prespore gene expression | decreased prestalk gene expression | increased prespore cell differentiation | delayed culmination |
DBS0350577 | pyk3- | pyk3 | decreased protein phosphorylation | decreased gene expression | aberrant protein localization to nucleus |
DBS0350581 | pyk3- | pyk3 | decreased protein phosphorylation | decreased gene expression |
DBS0304393 | pyk3-/ [act15]: T7: pyk3 | pyk3 | wild type |
DBS0350579 | pyk3-/ phg2- | phg2 | pyk3 | abolished gene expression | decreased protein phosphorylation | aberrant protein localization to nucleus |
DBS0236836 | pykA- | pykA | decreased growth rate | abolished aggregation |
DBS0236837 | pyr56- | pyr56 | increased resistance to 5-Fluoroorotic acid | abolished uracil biosynthetic process |
DBS0236838 | pyr56- | pyr56 | increased resistance to 5-Fluoroorotic acid | abolished uracil biosynthetic process |
DBS0351499 | pzoA- | pzoA | aberrant cellular response to fluid shear stress | aberrant chemotaxis to cAMP |
DBS0350017 | qdpr- | qdpr | decreased spore germination | decreased growth rate | abolished catalytic activity | aberrant response to oxidative stress |
DBS0350018 | qdpr-/ [act15]: pah | pah | qdpr | decreased growth rate |
DBS0236839 | qkgA- | qkgA-1 | qkgA-2 | increased mound size | delayed aggregation | aberrant vegetative growth | aberrant nucleus organization | increased growth rate | abolished negative chemotaxis |
DBS0351552 | qkgA- | qkgA-1 | qkgA-2 | aberrant aggregation | decreased actin filament polymerization | aberrant cytokinesis | decreased cell motility | decreased chemotaxis to cAMP |
DBS0350011 | qkgA-/ [act15]: bzpN: GFP | bzpN | qkgA-1 | qkgA-2 | abolished negative regulation of vegetative growth |
DBS0351560 | qtrt1- | qtrt1 | aberrant response to stimulus |
DBS0350263 | rab7A- | rab7A | decreased growth rate |
DBS0236841 | racB- | racB | decreased actin filament polymerization | delayed aggregation | aberrant fruiting body morphogenesis | decreased chemotaxis rate | decreased myosin II assembly |
DBS0236842 | racC- | racC | decreased protein localization to plasma membrane | decreased actin filament polymerization | aberrant cytokinesis | aberrant stream morphology | decreased chemotaxis rate | aberrant cell morphology | aberrant protein localization |
DBS0350272 | racC- | racC | aberrant cytokinesis | decreased growth rate | abolished positive regulation of chemorepellant activity |
DBS0237191 | racC-/ [act15]: CFP: racC | racC | increased actin filament polymerization |
DBS0235413 | racE- | racE | abolished cytokinesis | aberrant cortical actin cytoskeleton organization | abolished protein localization to cell cortex |
DBS0350271 | racE- | racE | decreased protein phosphorylation | increased lateral pseudopodium formation | aberrant cytokinesis | delayed aggregation | decreased growth rate | aberrant regulation of GTPase activity | aberrant protein localization to plasma membrane | decreased establishment of cell polarity | decreased chemotaxis to cAMP |
DBS0351308 | racE- | racE | aberrant cortical actin cytoskeleton organization | abolished protein localization to cell cortex | aberrant cytokinesis | decreased cell motility | aberrant cell morphology |
DBS0351348 | racE-/ [act15]: GFP: racE(G20V) | racE | decreased protein phosphorylation | decreased chemotaxis to cAMP |
DBS0351349 | racE-/ [act15]: GFP: racE(G23V) | racE | increased protein phosphorylation |
DBS0351350 | racE-/ [act15]: GFP: racE(S192D) | racE | increased protein phosphorylation | wild type |
DBS0351347 | racE-/ [act15]: GFP: racE(T25N) | racE | wild type |
DBS0351614 | racE-/ [act15]: GFP: racE(T25N/ S192D) | racE | wild type |
DBS0351351 | racE-/ [act15]: GFP: rasC(Q62L) | racE | rasC | decreased protein phosphorylation |
DBS0349949 | racE-/ [act15]: fttB | fttB | racE | decreased growth rate |
DBS0349946 | racE-/ [act15]: fttB: GFP | fttB | racE | abolished protein localization to cell cortex |
DBS0350956 | racE-/ [act15]racE(G20V) | racE | wild type |
DBS0350957 | racE-/ [act15]racE(T25N) | racE | abolished cytokinesis |
DBS0351505 | racF1- | racF1 | wild type |
DBS0236844 | racF2(G12V) | racF2 | decreased cell-cell adhesion |
DBS0236845 | racF2(N17T) | racF2 | increased cell-cell adhesion | decreased sexual fusion |
DBS0236843 | racF2- | racF2 | increased mound size | increased cell-cell adhesion | decreased sexual fusion |
DBS0236849 | racG- | racG | decreased cell motility | decreased protein localization to phagocytic vesicle |
DBS0236850 | racH- | racH | decreased exocytosis | aberrant protein localization to cytoplasmic vesicle | decreased pinocytosis | decreased defense response to Gram-negative bacterium | aberrant defense response to bacterium | decreased defense response to bacterium |
DBS0351149 | rapC- | rapC | increased number of mound tips | aberrant cytokinesis | increased cell-substrate adhesion | decreased cell motility | aberrant cell morphology |
DBS0266936 | rapgap1- | rapgap1 | decreased positive regulation of GTPase activity | increased actin filament polymerization | increased cell-substrate adhesion | decreased cell motility | decreased myosin II assembly | increased protein kinase activation |
DBS0266937 | rapgap1-/ [act15]: GFP: rapgap1 | rapgap1 | increased positive regulation of GTPase activity | increased lateral pseudopodium formation | decreased cell-substrate adhesion | increased myosin II assembly | increased actin filament polymerization | increased cell motility |
DBS0351487 | rapgap3- | rapgap3 | increased cell motility | increased activation of GTPase activity |
DBS0350864 | rapgap3-/ AX2 | rapgap3 | delayed aggregation | decreased chemotaxis to cAMP | decreased fruiting body size |
DBS0350863 | rapgap3-/ KAX3 | rapgap3 | delayed development of tipped mound | increased calcium-dependent cell-cell adhesion | decreased cell motility | aberrant cell migration to prestalk region | aberrant regulation of GTPase activity |
DBS0350316 | rapgap9- | rapgap9 | increased filopodium formation | increased actin filament polymerization | aberrant cytokinesis | decreased spore size | increased cell-substrate adhesion | decreased chemotaxis to cAMP |
DBS0350317 | rapgap9-/ [act15]: GFP: rapgap9 | rapgap9 | wild type |
DBS0350628 | rapgapB- | rapgapB | aberrant aggregation | increased cell-substrate adhesion | aberrant regulation of GTPase activity | aberrant actin filament organization |
DBS0350630 | rapgapB-/ [ecmAO]: RFP | ecmA | rapgapB | aberrant cell-cell adhesion |
DBS0350631 | rapgapB-/ [ecmA]: lacZ | rapgapB | aberrant cell migration to prestalk region |
DBS0350632 | rapgapB-/ [ecmO]: lacZ | rapgapB | aberrant cell migration to prestalk region |
DBS0350629 | rapgapB-/ [pspA]: RFP | pspA | rapgapB | aberrant cell-cell adhesion |
DBS0236852 | rasB- | rasB | decreased growth rate |
DBS0350836 | rasB- | rasB | decreased phagocytosis | decreased macropinocytosis | aberrant actin filament organization |
DBS0236853 | rasC-/ AX2 | rasC | increased rate of endocytosis | aberrant response to cAMP | decreased cell motility | increased vegetative cell size | abolished protein kinase activation | decreased protein kinase activation | decreased taxis | abolished aggregation | aberrant pseudopodium formation | aberrant actin filament organization | aberrant protein localization to cell cortex | aberrant cellular response to extracellular stimulus |
DBS0236854 | rasC-/ JH10 | rasC | wild type | aberrant gene expression | decreased protein kinase activation | abolished aggregation | abolished chemotaxis to cAMP |
DBS0237614 | rasC-/ [act15]: gbpD | gbpD | rasC | increased cell-substrate adhesion | aberrant cell morphology |
DBS0350740 | rasC-/ [rasC]: rasG | rasC | rasG | abolished activation of adenylate cyclase activity | abolished aggregation |
DBS0350742 | rasC-/ [rasC]: rasG(1-77(D30A)): rasC(79-189) | rasC | rasG | wild type |
DBS0350741 | rasC-/ [rasC]: rasG(D30A) | rasC | rasG | aberrant aggregation | decreased activation of adenylate cyclase activity |
DBS0236855 | rasC-/ dmpA- | dmpA | rasC | abolished stream development |
DBS0236856 | rasC-/ pikD1 | pikD | rasC | increased establishment of cell polarity | increased chemotaxis to cAMP | aberrant gene expression | aberrant fruiting body morphogenesis | decreased protein kinase activation | abolished aggregation |
DBS0236857 | rasC-/ rasD- | rasC | rasD | abolished aggregation |
DBS0236858 | rasC-/ rasG- | rasC | rasG | aberrant cell separation during cytokinesis | wild type | aberrant cell motility | decreased activation of adenylate cyclase activity | decreased gene expression | abolished guanylyl cyclase activity | abolished chemotaxis to folate | decreased growth rate | aberrant chemotaxis to folate | abolished protein kinase activation | abolished vegetative growth | decreased cell motility | increased protein level | abolished aggregation | delayed gene expression | abolished chemotaxis to cAMP | abolished positive regulation of chemorepellant activity |
DBS0266697 | rasC-/ rasG-/ [act15]: carA | carA-1 | carA-2 | rasC | rasG | decreased activation of adenylate cyclase activity | abolished activation of GTPase activity | decreased growth rate | abolished vegetative growth | abolished protein kinase activation | abolished cGMP-mediated signaling | abolished chemotaxis to cAMP |
DBS0350480 | rasC-/ rasG-/ [rasG]: rasD | rasC | rasD | rasG | decreased chemotaxis to folate |
DBS0350482 | rasC-/ rasG-/ [rasG]: rasD(1-104): rasG(103-189) | rasC | rasD | rasG | decreased chemotaxis to folate |
DBS0350481 | rasC-/ rasG-/ [rasG]: rasG | rasC | rasG | wild type |
DBS0350483 | rasC-/ rasG-/ [rasG]: rasG(1-104): rasD(103-187) | rasC | rasD | rasG | wild type |
DBS0351062 | rasC-/ rasG-/ [unk]: carA | carA-1 | carA-2 | rasC | rasG | decreased protein localization to plasma membrane |
DBS0351449 | rasC-/ rasS- | rasC | rasS | increased macropinocytosis |
DBS0351213 | rasC-[act15]: rasG(S17N) | rasC | rasG | abolished activation of GTPase activity | decreased chemotaxis to cAMP |
DBS0236860 | rasD- | rasD | aberrant thermotaxis | aberrant phototaxis |
DBS0351459 | rasD-/ AX3 | rasD | increased gene expression | increased prespore cell differentiation |
DBS0236862 | rasG-/ AX2 | rasG | decreased pinocytosis | decreased gene expression | delayed aggregation | aberrant taxis | decreased cGMP-mediated signaling | decreased protein kinase activation | delayed gene expression |
IR15 | rasG-/ AX2 | rasG | aberrant cell separation during cytokinesis | aberrant filopodium formation | decreased actin filament polymerization | decreased growth rate | increased vegetative cell size | decreased macropinocytosis | decreased cell motility | decreased protein kinase activation | decreased establishment of cell polarity | aberrant actin filament organization |
IR17 | rasG-/ AX3 | rasG | aberrant cytokinesis | decreased cell motility | increased vegetative cell size |
DBS0351460 | rasG-/ AX3 | rasG | increased prestalk cell differentiation |
DBS0236863 | rasG-/ JH10 | rasG | aberrant cell separation during cytokinesis | wild type | decreased gene expression | delayed aggregation | abolished activation of GTPase activity | aberrant chemotaxis to folate | decreased growth rate | decreased cGMP-mediated signaling | decreased protein kinase activation | delayed gene expression |
DBS0236864 | rasG-/ [OE]: rasB | rasB | rasG | decreased growth rate |
DBS0350572 | rasG-/ [act15]: FLAG: rasG(K169R,K173R,K176R,K178R) | rasG | aberrant cytokinesis |
DBS0350571 | rasG-/ [act15]: FLAG: rasG(K169R,K173R,K176R,K178R,K179R,K180R,K184R) | rasG | decreased protein modification |
DBS0350448 | rasG-/ [dscB]: rasG(S17N) | rasG | decreased positive regulation of GTPase activity | decreased actin filament polymerization | decreased protein kinase activation | decreased chemotaxis to cAMP |
DBS0351447 | rasG-/ rasS- | rasG | rasS | decreased macropinocytosis |
DBS0236872 | rasS-/ AX2 | rasS | decreased macropinocytosis | decreased cell motility | aberrant pinosome maturation | decreased establishment of cell polarity |
DBS0351446 | rasS-/ AX2 | rasS | aberrant macropinocytosis |
DBS0236873 | rasS-/ DH1 | rasS | decreased rate of endocytosis | decreased growth rate | increased actin filament polymerization | abolished vegetative growth | increased cell motility | aberrant cytoskeleton organization |
DBS0351314 | rasS-/ DdB | rasS | decreased macropinocytosis | increased cell motility |
DBS0236874 | rasZ- | rasZ | wild type |
DBS0351598 | rbdB- | rbdB | abolished pre-miRNA processing |
DBS0350261 | rbg3- | rbg3 | precocious development | increased growth rate |
DBS0236877 | rblA- | rblA | increased cell migration to prestalk region | decreased spore germination | decreased gene expression | increased gene expression | abolished negative regulation of vegetative growth | decreased growth rate | aberrant vegetative growth | decreased vegetative cell size | precocious development | increased prestalk cell differentiation |
DBS0349999 | rblA-/ [act15]: GFP | rblA | increased cell migration to prestalk region |
DBS0349996 | rblA-/ [act15]: GFP/ [act15]: myc: btg | btg | rblA | increased cell migration to prestalk region |
DBS0349994 | rblA-/ [btg]: lacZ | btg | rblA | decreased gene expression |
DBS0236878 | rbrA- | rbrA | increased gene expression | decreased gene expression | development arrests at slug stage | aberrant prespore gene expression | decreased cell migration to prestalk region | decreased phototaxis | decreased sporulation |
DBS0236879 | rbrA-/ [unk]: rbrA | rbrA | wild type |
DBS0305613 | rccA- | rccA | increased resistance to cheating during development |
DBS0236880 | rckA- | rckA | increased mound size | precocious aggregation | delayed slug development | delayed prestalk gene expression | delayed prespore gene expression | increased chemotaxis rate |
DBS0236885 | rckA-/ [act15]: myc: rckA | rckA | delayed development | decreased chemotaxis rate |
DBS0236881 | rckA-/ [act15]: myc: rckA(C551A) | rckA | delayed slug development | decreased chemotaxis rate |
DBS0236882 | rckA-/ [act15]: myc: rckA(E510G) | rckA | wild type | decreased chemotaxis rate |
DBS0236883 | rckA-/ [act15]: myc: rckA(E510G/ N511A) | rckA | delayed slug development | decreased chemotaxis rate |
DBS0236884 | rckA-/ [act15]: myc: rckA(K867A) | rckA | development arrests at mound stage | decreased chemotaxis rate |
FR17 | rdeA- | rdeA | precocious aggregation | decreased mound size | aberrant fruiting body morphogenesis | precocious development | precocious gene expression |
HH201 | rdeA- | rdeA | aberrant chemotaxis to cAMP | increased cAMP level |
WTC10 | rdeA- | rdeA | aberrant chemotaxis to cAMP | increased cAMP level | decreased macropinocytosis |
FR17 | rdeA- | rdeA | precocious aggregation | decreased mound size | aberrant fruiting body morphogenesis | precocious development | precocious gene expression |
DBS0236886 | rdeA-/ [act15]: rdeA | rdeA | wild type |
DBS0350688 | rdeA-/ acaA- | acaA | rdeA | increased cAMP level | decreased sporulation |
DBS0350468 | rdiA- | rdiA | decreased pinocytosis | decreased protein localization to cell cortex | decreased protein level | decreased actin filament polymerization | aberrant contractile vacuole morphology | decreased growth rate | aberrant cytokinesis |
DBS0351504 | rdiA- | rdiA | aberrant cytokinesis |
DBS0236887 | recA- | recA | decreased resistance to hydrogen peroxide | aberrant response to UV | decreased resistance to mitomycin C |
DBS0266664 | redA- | redA | development arrests at mound stage | aberrant mound color |
DBS0350511 | redA- | redA | decreased defense response to Gram-negative bacterium |
DG1047 | redA- | redA | development arrests at mound stage | aberrant mound color |
DBS0236889 | regA- | regA | increased resistance to cisplatin | aberrant chemotaxis to cAMP | increased cAMP level | aberrant fruiting body morphogenesis |
DBS0236958 | regA- | regA | decreased spore germination | precocious sporulation | abolished protein localization to cell cortex | increased lateral pseudopodium formation | aberrant chemotaxis to cAMP |
HM332 | regA- | regA | decreased lateral pseudopodium retraction |
HR45 | regA- | regA | aberrant fruiting body morphogenesis |
HM1015 | regA- | regA | increased cAMP level | decreased macropinocytosis | aberrant oscillatory cAMP signaling |
DBS0350372 | regA-/ KAX3 | regA | precocious sporulation | increased sporulation |
DBS0235706 | regA-/ [act15]: dhkK(D1125N) | dhkK | regA | aberrant fruiting body morphogenesis | precocious development |
DBS0235708 | regA-/ [act15]: dhkK(H825Q) | dhkK | regA | aberrant fruiting body morphogenesis | precocious development |
DBS0351475 | regA-/ [act15]: erkA | erkA | regA | delayed slug development |
DBS0351472 | regA-/ [act15]: regA(R588A,R589A,L594A,I595A,L596A) | regA | delayed development |
DBS0351284 | regA-/ [act15]: regA(S142A) | regA | aberrant fruiting body morphogenesis | precocious development |
DBS0351283 | regA-/ [act15]: regA(S142E) | regA | delayed development |
DBS0351285 | regA-/ [act15]: regA(S413A) | regA | increased mound size | delayed development |
DBS0351286 | regA-/ [act15]: regA(S413E) | regA | increased mound size | delayed development |
DBS0351287 | regA-/ [act15]: regA(T676A) | regA | delayed sporulation |
DBS0351288 | regA-/ [act15]: regA(T676E) | regA | aberrant fruiting body morphogenesis | precocious development |
DBS0350689 | regA-/ [regA]: regA | regA | wild type |
DBS0350670 | regA-/ [regA]: regA(D212N) | regA | precocious sporulation |
DBS0350380 | regA-/ dhkD- | dhkD | regA | aberrant fruiting body morphogenesis |
DBS0351473 | regA-/ regA(R588A,R589A,L594A,I595A,L596) | regA | precocious sporulation | decreased mound size | increased protein binding | aberrant fruiting body morphogenesis |
DBS0236891 | regA-/ tagB- | regA | tagB | decreased sporulation |
DBS0236892 | regA-/ tagC- | regA | tagC | decreased sporulation |
DBS0266818 | repB(1-754) | repB | aberrant response to UV |
HM1351 | rev3- | rev3 | aberrant vegetative growth | decreased resistance to cisplatin |
HM1451 | rev3-/ xpf- | rev3 | xpf | decreased resistance to cisplatin |
DBS0236893 | rgaA- | rgaA | abolished cell migration to prestalk region | aberrant cytokinesis | abolished stalk cell differentiation | decreased protein kinase activation | abolished culmination | decreased sporulation |
DBS0349935 | rgaA- | rgaA | aberrant stalk morphogenesis | increased number of tip-organizers | aberrant cellular response to fluid shear stress | increased actin filament polymerization | increased growth rate | increased cell motility | aberrant actin filament organization |
DBS0350398 | rgaA- | rgaA | increased lateral pseudopodium formation | decreased myosin II assembly | increased chemotaxis rate |
DBS0349921 | rgaA-/ [act15]: GFP-mhcA | rgaA | aberrant stalk morphogenesis | aberrant development of tipped mound | abolished protein localization to apical plasma membrane |
DBS0349937 | rgaA-/ ctxA- | ctxA | rgaA | aberrant cytokinesis | abolished protein localization to cleavage furrow |
DBS0349936 | rgaA-/ gapA- | gapA | rgaA | aberrant cellular response to fluid shear stress | aberrant cytokinesis | abolished protein localization to cleavage furrow | increased cell motility |
DBS0350401 | rgaA-/ gapA- | gapA | rgaA | decreased protein localization to cleavage furrow | increased myosin II assembly | aberrant mitotic spindle organization | increased actin filament polymerization | decreased chemotaxis to cAMP | increased protein kinase activation |
DBS0350406 | rgaA-/ gapA-/ [unk]: myc: gapA(R308E/ K317E) | gapA | rgaA | increased protein kinase activation |
DBS0350402 | rgaA-/ iqgC- | iqgC | rgaA | decreased myosin II assembly | increased protein kinase activation |
DBS0351526 | rgbA-/ AX2 | rgbA | aberrant macropinocytosis | aberrant activation of GTPase activity | decreased macropinocytosis | aberrant engulfment during phagocytosis | decreased chemotaxis to folate |
DBS0351527 | rgbA-/ DdB | rgbA | aberrant macropinocytosis | increased activation of GTPase activity |
DBS0350019 | rgfA- | rgfA | wild type |
DBS0350020 | rgfA-/ [act15]: rgfA | rgfA | decreased chemotaxis to folate | delayed development |
DBS0350108 | rheb- | rheb | increased phagocytosis |
DBS0236894 | rhgA- | rhgA | wild type |
DBS0350192 | ric8- | ric8 | abolished gene expression | abolished chemotaxis to folate | decreased chemotaxis to cAMP | abolished aggregation | aberrant signal transduction |
DBS0350193 | ric8-/ [act15]: GFP: ric8 | ric8 | wild type |
DBS0236900 | ripA- | ripA | decreased guanylyl cyclase activity | abolished activation of adenylate cyclase activity | decreased chemotaxis rate | decreased taxis | abolished aggregation | decreased establishment of cell polarity | aberrant regulation of protein kinase activity | decreased myosin II assembly | increased phagocytosis |
DBS0350770 | ripA-/ [act15]: GFP: rapA(G12V) | rapA | ripA | decreased protein kinase activation |
DBS0350115 | ripA-/ [act15]: GFP: rheb(Q64L) | rheb | ripA | increased phagocytosis |
DBS0236902 | ripA-/ [unk]: ripA(K680E/ R681E) | ripA | aberrant sorocarp development | decreased chemotaxis rate |
DBS0236901 | ripA-/ [unk]ripA | ripA | wild type |
DBS0351068 | rnf113- | rnf113 | delayed aggregation | increased cell-substrate adhesion | decreased cell motility |
DBS0351042 | rnlA- | rnlA | decreased thermotaxis | decreased growth rate | decreased defense response to bacterium | decreased phototaxis |
DBS0236903 | rnpA- | rnpA | increased gene expression |
DBS0350096 | roco11- | roco11 | increased stalk length |
DBS0350095 | roco4- | roco4 | delayed slug development | aberrant stalk development | delayed culmination |
DBS0350100 | roco4-/ [unk]: roco4(1018-1292(G1179S)) | roco4 | increased catalytic activity |
DBS0350098 | roco4-/ [unk]: roco4(1018-1292(S1187A)) | roco4 | abolished catalytic activity |
DBS0350099 | roco4-/ [unk]: roco4(1018-1292(S1189A)) | roco4 | decreased catalytic activity |
DBS0238225 | rpkA- | rpkA | development arrests at loose mound stage | decreased defense response to Gram-negative bacterium | aberrant cellular response to nitrogen starvation | decreased phagocytosis | decreased cell motility | decreased establishment of cell polarity | abolished aggregation | aberrant cellular response to extracellular stimulus |
DBS0236906 | rrpA- | rrpA | abolished post-transciptional gene silencing by RNA |
DBS0350178 | rrpA-/ rrpB-/ rrpC- | rrpA | rrpB | rrpC | increased gene expression | decreased gene expression |
DBS0350189 | rrpA-/ rrpB-/ rrpC-/ [act6]: lacZ/ [RNAi]lacZ | rrpA | rrpB | rrpC | abolished transitive RNA interference |
DBS0350176 | rrpA-/ rrpC- | rrpA | rrpC | increased gene expression | decreased gene expression |
DBS0350187 | rrpA-/ rrpC-/ [act6]: lacZ/ [AS]lacZ | rrpA | rrpC | aberrant production of siRNA involved in RNA interference |
DBS0350182 | rrpA-/ rrpC-/ [act6]: lacZ/ [RNAi]lacZ | rrpA | rrpC | abolished transitive RNA interference |
DBS0350177 | rrpB-/ rrpC- | rrpB | rrpC | increased gene expression | decreased gene expression |
DBS0350185 | rrpB-/ rrpC-/ [act6]: lacZ/ [AS]lacZ | rrpB | rrpC | aberrant production of siRNA involved in RNA interference |
DBS0350184 | rrpB-/ rrpC-/ [act6]: lacZ/ [RNAi]lacZ | rrpB | rrpC | abolished transitive RNA interference |
DBS0350209 | rrpC- | rrpC | decreased gene expression | increased gene expression |
DBS0350219 | rrpC-/ [act15]: pre-miRNA | rrpC | increased pre-miRNA processing |
DBS0350216 | rrpC-/ [act6]: LacZ/ [RNAi]lacZ | rrpC | abolished transitive RNA interference |
DBS0350217 | rrpC-/ [act6]: lacZ/ [AS]lacZ | rrpC | aberrant production of siRNA involved in RNA interference |
DBS0236875 | rtoA- | rtoA | decreased rate of endocytosis | increased defense response to Gram-negative bacterium | increased prestalk cell differentiation | delayed culmination |
DBS0236911 | rtoA- | rtoA | delayed development |
DBS0236914 | rzpA- | rzpA | aberrant aggregation | decreased slug migration | increased mound size | increased prespore gene expression | decreased prestalk gene expression | delayed development |
DBS0309040 | sadA- | sadA | abolished protein localization to cell surface | decreased phagocytosis | decreased protein stabilization |
DBS0236921 | sadA- | sadA | abolished cell-substrate adhesion | decreased phagocytosis | aberrant cytokinesis | increased growth rate | aberrant actin filament organization | aberrant cell morphology |
DBS0350974 | sadA-/ [act15]: gpaH | gpaH | sadA | aberrant cytokinesis |
DBS0349790 | sadA-/ [act15]: sadA(1-923): GFP | sadA | decreased cell-substrate adhesion |
DBS0349792 | sadA-/ [act15]: sadA(S924A/ S925A): GFP | sadA | wild type |
DBS0349791 | sadA-/ [act15]: sadA(S924E/ S925E): GFP | sadA | decreased cell-substrate adhesion |
DBS0236922 | sadA-/ [act15]: sadA: GFP | sadA | wild type |
DBS0351564 | sbdS(1-30,TS18,31-274) | sbds | development arrests at loose mound stage | aberrant cellular process | abolished vegetative growth |
DBS0351566 | sbdS(1-30,TS18,31-274)/ [act15]: eIF(T56K) | eIF6 | sbds | wild type |
DG1105 | scaA- | scaA | abolished aggregation |
DBS0350825 | scaA- | scaA | decreased actin filament polymerization | aberrant chemotaxis to cAMP | abolished activation of GTPase activity | decreased protein kinase activation | abolished aggregation |
DBS0236924 | scrA- | scrA | increased number of tip-organizers | abolished protein localization to endolysosome | decreased exocytosis | decreased pinocytosis | decreased actin filament polymerization | increased lateral pseudopodium formation | decreased phagocytosis | decreased vegetative cell size | decreased fruiting body size | precocious development |
IR46 | scrA- | scrA | aberrant mitotic spindle organization | aberrant cytokinesis | abolished activation of GTPase activity | decreased vegetative cell size | decreased cell motility | aberrant cellular response to stress | aberrant pseudopodium formation | increased bleb assembly | abolished positive regulation of chemorepellant activity |
IR48 | scrA- | scrA | decreased growth rate | aberrant cytokinesis | decreased bleb assembly | decreased phototaxis |
DBS0236925 | scrA- | scrA | increased filopodium formation | decreased protein level | aberrant macropinocytosis | aberrant cytokinesis | decreased macropinocytosis | decreased cell motility | aberrant actin filament organization | aberrant pseudopodium formation |
DBS0351524 | scrA-/ [act15]: scrA(R177A,R179A,K180A,R183A,R184A,R187A,K190A,K191A,K194A) | scrA | decreased bleb assembly | increased cellular localization | aberrant pseudopodium formation |
DBS0351611 | scrA-/ [act15]: scrA(S287,290,301,335,339,384,388,389,430,432,433,437,440A) | scrA | aberrant pseudopodium formation |
DBS0351522 | scrA-/ [act15]: scrA(S430A,S432A,S433A,S437A,S440A) | scrA | decreased bleb assembly | increased cellular localization | aberrant pseudopodium formation |
DBS0351523 | scrA-/ [act15]: scrA(S430D,S432D,S433D,S437D,S440D) | scrA | decreased pseudopodium size |
DBS0349927 | scrA-/ [act15]: wasA: GFP/ [ act8]: RFP: arcD | scrA | decreased establishment of cell polarity | decreased pseudopodium formation |
DBS0350063 | scrA-/ [tet]: scrA/ mhcA- | mhcA | scrA | aberrant cytokinesis |
DBS0351610 | scrA-/ [tet]: scrA/ wasA- | scrA | wasA | aberrant cell motility | abolished vegetative growth | abolished bleb assembly | aberrant pseudopodium formation |
DBS0238440 | scrA-/ [unk]: scrA(97-443): GFP | scrA | aberrant cytokinesis | increased vegetative cell size | decreased chemotaxis to cAMP | aberrant cytoskeleton organization |
DBS0238446 | scrA-/ [unk]: scrA: GFP | scrA | wild type |
SB18 | scrA-/ napA- | napA | scrA | decreased actin filament polymerization | decreased cell motility |
SB7 | scrA-/ pirA- | pirA | scrA | decreased vegetative cell size |
HM1163 | sec1-/ sec1(M213K/ E258G/ M427V/ K527I/ T541N/ F558S/ N581D) | sec1 | abolished cell motility |
HM1325 | sec1-/ sec1(M250L/ A296V/ M427L/ S435R/ K505N/ V552D/ H570Q) | sec1 | abolished cytokinesis | aberrant hypotonic response | abolished cell motility | aberrant plasma membrane organization | aberrant cell morphology |
DBS0350286 | sec1-/ sec1(M250L/ A296V/ M427L/ S435R/ K505N/ V552D/ H570Q)/ gppA: GFP | gppA | sec1 | abolished contractile vacuole discharge |
DBS0350101 | sec7- | sec7 | aberrant cell motility | decreased phagocytosis | decreased growth rate | aberrant phototaxis | decreased protein secretion |
DBS0306234 | secG- | secG | decreased cell-substrate adhesion | decreased chemotaxis rate |
DBS0351035 | seiP- | seiP | aberrant lipid droplet formation |
DBS0350264 | sepA- | sepA | aberrant cytokinesis | delayed aggregation | decreased growth rate | decreased fruiting body size |
DBS0351077 | sepA- | sepA | aberrant gene expression | increased cell-substrate adhesion | decreased cell motility |
DBS0350906 | sepA- | sepA | decreased protein phosphorylation | aberrant pseudopodium formation |
DBS0351252 | sesn- | sesn | increased mound size | aberrant standing slug morphology | decreased gene expression | decreased autophagy | aberrant response to oxidative stress |
DBS0236928 | set1- | set1 | precocious aggregation | abolished histone H3-K4 methylation | precocious gene expression |
HG1132 | sevA- | sevA | wild type |
DG1008 | sfbA- | sfbA | decreased fruiting body size |
DBS0350889 | sgcA-/ AX2 | sgcA | aberrant aggregation | decreased guanylyl cyclase activity | aberrant chemotaxis to cAMP |
DBS0350888 | sgcA-/ AX3 | sgcA | aberrant aggregation | decreased guanylyl cyclase activity | aberrant chemotaxis to cAMP |
SA576 | sgkA- | sgkA | decreased resistance to carboplatin | decreased growth rate | decreased resistance to cisplatin |
HM1093 | sgkA-/ sgkB- | sgkA | sgkB | decreased resistance to carboplatin | decreased growth rate | decreased resistance to cisplatin |
HM1091 | sgkB- | sgkB | decreased resistance to carboplatin | decreased growth rate | decreased resistance to cisplatin |
SA555 | sglA- | sglA | increased stalk width | increased resistance to cisplatin | increased mound size | decreased lateral pseudopodium retraction | decreased gene expression | abolished slug migration | decreased cell motility | decreased chemotaxis rate | decreased fruiting body size | aberrant cytoskeleton organization | decreased sporulation | increased resistance to carboplatin |
SA554 | sglA- | sglA | delayed aggregation | decreased mound size |
DBS0236934 | shkA- | shkA | aberrant aggregation | decreased phagocytosis | aberrant cytokinesis | decreased chemotaxis rate | decreased fruiting body size | decreased establishment of cell polarity | aberrant actin filament organization |
DBS0236935 | sibA- | sibA | decreased cell-substrate adhesion | decreased phagocytosis |
DBS0302653 | sibC- | sibC | decreased phagocytosis |
DBS0236936 | sigB- | sigB | wild type |
DBS0236937 | sigD- | sigD | wild type |
DBS0266513 | sigN(group1)- | sigN1 | sigN105-1 | sigN2 | sigN25 | sigN3 | sigN4 | sigN5 | wild type |
DBS0266514 | sigN(group2)- | DDB_G0271820 | sigN10 | sigN11 | sigN12 | sigN14 | sigN6 | sigN7 | sigN8 | sigN9 | wild type |
DBS0351170 | sir2A- | sir2A | abolished slug migration | increased number of mound tips | increased gene expression | decreased gene expression | decreased growth rate | aberrant sorocarp development | decreased autophagy | decreased chemotaxis to cAMP | decreased cAMP level |
DBS0350859 | sir2D- | sir2D | decreased gene expression | increased gene expression | increased number of mound tips | delayed aggregation | decreased growth rate | decreased autophagy | decreased mound size | decreased stalk length |
DBS0350860 | sir2D-/ [ecmAO]: lacZ | sir2D | decreased prestalk cell differentiation |
DBS0350861 | sir2D-/ [pspA]: lacZ | sir2D | aberrant prespore cell differentiation |
DBS0350985 | slc4- | slc4 | aberrant transport |
DBS0349958 | sma- | sma | increased chemotaxis to folate | decreased gene expression | increased cell-substrate adhesion | decreased vegetative cell size | increased cell-cell adhesion |
DBS0349957 | sma-/ ampA/ [ampA]: ampA | ampA | sma | decreased chemotaxis to folate |
DBS0350327 | smdA-/ [pspA]: lacZ | smdA | aberrant gene expression |
DBS0236938 | smkA- | smkA | aberrant cytokinesis | delayed development | decreased chemotaxis rate | decreased myosin II assembly |
HDB7YA | smlA- | smlA | increased oscillatory cAMP signaling | decreased cell-cell adhesion | aberrant cellular metabolic process | decreased response to Gram-negative bacterium | increased resistance to cisplatin | decreased protein level | decreased guanylyl cyclase activity | increased myosin II assembly | increased actin filament polymerization | decreased cGMP-mediated signaling | decreased mound size | increased protein level | decreased secretion of lysosomal enzymes | increased cell motility | decreased fruiting body size |
DBS0302657 | smlA-/ cnrN- | cnrN | smlA | decreased fruiting body size |
DBS0236940 | smlA-/ ctnA- | ctnA | smlA | increased cell-cell adhesion |
DBS0304496 | smlA-/ sslA1(CR11) | smlA | sslA1 | increased fruiting body size |
DBS0350977 | snfA- | snfA | decreased pinocytosis | increased cell death | decreased autophagic cell death | decreased phagocytosis | decreased number of autophagosomes | aberrant sorocarp development | decreased prespore cell differentiation | aberrant gene expression | aberrant protein modification | increased growth rate | aberrant prestalk cell differentiation | aberrant sporulation |
DBS0302523 | sodC- | sodC | aberrant cytokinesis |
DBS0302524 | sodC- | sodC | aberrant aggregation | decreased positive regulation of GTPase activity | decreased actin filament polymerization | increased actin filament polymerization | aberrant chemotaxis to cAMP | increased protein localization to plasma membrane | decreased chemotaxis rate | aberrant regulation of GTPase activity | aberrant protein localization to plasma membrane | aberrant cell morphology | increased protein kinase activation |
DBS0351063 | sodC-/ [unk]: rasG(C118A) | rasG | sodC | aberrant regulation of GTPase activity |
DBS0350894 | sodD- | sodD | aberrant response to UV |
DBS0351196 | sogA- | sogA | aberrant chemotaxis to cAMP | increased activation of GTPase activity |
DBS0350966 | spaA- | spaA | abolished sporulation |
AK1346 | spc3- | spc3 | decreased response to Gram-negative bacterium |
DBS0350891 | spdA- | spdA | decreased substrate adhesion-dependent cell spreading | decreased phagocytosis |
DBS0350892 | spdA-ins | spdA | decreased growth rate | increased substrate adhesion-dependent cell spreading | increased phagocytosis |
HL351 | spiA- | spiA | decreased spore germination |
DBS0236943 | spkA-1-/ spkA-2- | spkA-1 | spkA-2 | decreased cell-substrate adhesion | aberrant cytokinesis | decreased mound size | decreased chemotaxis rate | decreased establishment of cell polarity | aberrant cell morphology | decreased fruiting body size |
DBS0236944 | spkA-1-/ spkA-2-/ [act15]: spkA: FLAG | spkA-1 | spkA-2 | aberrant aggregation | decreased chemotaxis rate | aberrant actin filament organization | decreased establishment of cell polarity |
DBS0236945 | splA- | splA | abolished sporulation | aberrant spore morphology | increased sorus size | aberrant sorus color | decreased stalk length |
DBS0350131 | splB- | splB | abolished protein tyrosine phosphorylation | abolished protein localization to nucleus | abolished response to DIF-1 | decreased gene expression |
DBS0350582 | splB-/ pyk3- | pyk3 | splB | abolished gene expression | abolished protein localization to nucleus | aberrant sorocarp development | abolished protein phosphorylation |
DBS0236947 | spnA- | spnA | abolished prespore cell differentiation | development arrests at mound stage | abolished prestalk cell differentiation | aberrant sorocarp development |
DBS0236948 | spnA-/ arkA- | arkA | spnA | decreased gene expression | increased sorus size | decreased stalk length | delayed gene expression |
DBS0236949 | spr- | spr | decreased spore germination | decreased pteridine level | decreased cytochrome C oxidase activity | decreased growth rate |
DBS0350914 | spsA- | spsA | decreased stalk length |
DBS0351174 | srcp1- | srcp1 | aberrant protein modification |
DBS0236950 | srfA(1-8): lacZ | srfA | decreased slug migration | aberrant fruiting body morphogenesis | delayed culmination |
DBS0236951 | srfA- | srfA | aberrant spore morphology | decreased spore germination | aberrant spore coat morphology | decreased gene expression |
DBS0266691 | srfB- | srfB | abolished stream development | aberrant extracellular cAMP signaling pathway | increased lateral pseudopodium formation | precocious aggregation | decreased growth rate | increased pinocytosis | aberrant cytokinesis | precocious gene expression |
DBS0304409 | srsA- | srsA | increased mound size | decreased gene expression | increased gene expression | delayed aggregation |
DBS0304497 | sslA1-/ sslA1(CR11) | sslA1 | increased fruiting body size | decreased oscillatory cAMP signaling | decreased cGMP-mediated signaling |
DBS0236952 | stkA- | stkA | decreased gene expression | increased prestalk gene expression | delayed prespore gene expression | aberrant fruiting body morphogenesis | increased prestalk cell differentiation |
HM1157 | stlA- | stlA | aberrant aggregation | abolished sporulation | wild type | increased gene expression | decreased gene expression | aberrant stream morphology | decreased spore cell differentiation | decreased chemotaxis to cAMP | aberrant sorus color | abolished MPBD level | decreased cAMP level | aberrant sporulation |
DBS0350222 | stlA-/ [cotB]: lacZ | stlA | decreased sporulation | aberrant prespore cell differentiation |
DBS0350223 | stlA-/ stlB- | stlA | stlB | decreased gene expression | increased gene expression | aberrant gene expression | decreased stalk width |
DBS0350224 | stlA-/ stlB-/ [ecmA]: lacZ | stlA | stlB | decreased prestalk cell differentiation |
HM1154 | stlB- | stlB | abolished DIF-1 biosynthesis | abolished prestalk B cell differentiation | aberrant gene expression | aberrant fruiting body morphogenesis | decreased prestalk O cell differentiation | abolished lower cup formation | abolished outer basal disc formation | decreased prestalk cell differentiation |
DBS0351220 | stlB- | stlB | abolished autophagosome organization | abolished autophagic cell death |
DBS0350409 | stlB-/ [act15]: stlB | stlB | wild type |
DBS0349941 | sunB- | sunB | increased number of tip-organizers | aberrant cytokinesis |
DBS0304547 | svkA- | svkA | delayed cell separation during cytokinesis | aberrant cytokinesis | aberrant fruiting body morphogenesis |
DBS0236055 | swip- | swip | aberrant protein localization to cytoplasm | abolished exocytosis | abolished phagosome reneutralization | abolished actin filament polymerization | aberrant protein localization |
AK1321 | swp1- | swp1 | decreased response to Gram-positive bacterium |
AK1200 | tagA- | tagA | decreased spore cell differentiation | aberrant fruiting body morphogenesis |
AK859 | tagA- | tagA | decreased spore germination | increased number of mound tips | decreased spore cell differentiation | increased prestalk A cell differentiation | delayed culmination | decreased sporulation |
AK1201 | tagA-/ [ecmA]: GFP | tagA | abolished cell migration to prestalk region |
AK228 | tagB- | tagB | abolished sporulation | abolished DIF-1 biosynthesis | development arrests at mound stage | aberrant prestalk A cell differentiation |
DBS0350637 | tagB-/ [pkaC]: pkaC | pkaC | tagB | aberrant response to biotic stimulus | abolished spore cell differentiation |
DBS0350672 | tagB-/ pkaR- | pkaR | tagB | decreased sporulation |
DBS0236974 | tagB-/ psmA1- | psmA1 | tagB | abolished sporulation |
DBS0236975 | tagC- | tagC | abolished sporulation | development arrests at mound stage |
DBS0350698 | tagC-/ [pkaC]: pkaC | pkaC | tagC | development arrests at mound stage | abolished spore cell differentiation |
DBS0236976 | talA- | talA | decreased protein level | decreased cell-substrate adhesion | aberrant cytokinesis | decreased phagocytosis | aberrant cell morphology |
HG1666 | talA- | talA | decreased cell-cell adhesion | decreased cell-substrate adhesion | aberrant cytokinesis | decreased growth rate | decreased phagocytosis | increased cell-substrate adhesion |
HG1663 | talA- | talA | decreased cell-substrate adhesion |
HG1664 | talA- | talA | decreased uropod retraction | decreased growth rate | decreased phagocytosis | aberrant mitotic actomyosin contractile ring contraction |
HG1665 | talA- | talA | decreased cell-cell adhesion | aberrant cytokinesis |
DBS0304585 | talA-/ [act15]: FLAG: talB | talA | talB | decreased cell-substrate adhesion |
DBS0237616 | talA-/ [act15]: gbpD | gbpD | talA | increased cell-substrate adhesion | aberrant cell morphology | increased pseudopodium formation |
DBS0238395 | talA-/ [act15]: rapA(G12V) | rapA | talA | increased cell-substrate adhesion |
DBS0350442 | talA-/ sibA- | sibA | talA | wild type |
DBS0304581 | talA-/ talB- | talA | talB | development arrests at loose mound stage | abolished cell-substrate adhesion | aberrant cytokinesis | abolished cell motility | increased bleb assembly |
DBS0304582 | talA-/ talB-/ [act15]: FLAG: talB | talA | talB | wild type |
DBS0350713 | talA-/ talB-/ [act15]: talB(K16A) | talA | talB | decreased cell-substrate adhesion |
HKT104 | talB- | talB | decreased slug migration | aberrant extracellular cAMP signaling pathway | aberrant cellular process | decreased cell motility | development arrests at tipped mound stage | increased protein level | aberrant signal transduction |
DBS0302472 | talB- | talB | abolished autophagosome organization | abolished autophagic cell death | aberrant autophagic cell death |
DBS0304586 | talB-/ [act15]: talA: GFP | talA | talB | aberrant fruiting body morphogenesis |
DBS0350712 | talB-/ [act15]: talB(K16A) | talB | development arrests at tipped mound stage |
DBS0351501 | talB-/ pikB- | pikB | talB | aberrant cellular process |
DBS0351346 | tert- | tert | increased gene expression | decreased gene expression | aberrant cell adhesion | aberrant chemotaxis to cAMP | aberrant sorocarp development | delayed development | aberrant oscillatory cAMP signaling | decreased cAMP level |
DBS0351559 | tert- | tert | decreased catalytic activity | increased gene expression |
AK1505 | tgrB1- | tgrB1 | development arrests at loose mound stage | delayed sporulation | decreased cell motility | decreased sporulation |
DBS0351148 | tgrB1-/ tgrB1(1-827): HA | tgrB1 | development arrests at mound stage |
AK1540 | tgrB1-/ tgrC1- | tgrB1 | tgrC1 | development arrests at loose mound stage | abolished cell-cell self recognition | aberrant oscillatory cAMP signaling |
AK1549 | tgrB1-/ tgrC1-/ QS31|tgrB1/ tgrC1 | tgrB1 | tgrC1 | wild type |
AK1552 | tgrB1-/ tgrC1-/ QS38|tgrB1/ tgrC1 | tgrB1 | tgrC1 | wild type |
AK1555 | tgrB1-/ tgrC1-/ QS45|tgrB1/ tgrC1 | tgrB1 | tgrC1 | wild type |
AK1546 | tgrB1-/ tgrC1-/ QS4|tgrB1/ tgrC1 | tgrB1 | tgrC1 | wild type |
AK1664 | tgrB1-/ tgrC1-/ alg9(-19ins) | alg9 | tgrB1 | tgrC1 | decreased sporulation |
DBS0351131 | tgrB1-/ tgrC1-/ tgrB1(G275D) | tgrB1 | tgrC1 | wild type |
DBS0351132 | tgrB1-/ tgrC1-/ tgrB1(G307D) | tgrB1 | tgrC1 | wild type |
DBS0351133 | tgrB1-/ tgrC1-/ tgrB1(L846F) | tgrB1 | tgrC1 | aberrant standing slug morphology | increased number of mound tips | decreased fruiting body size |
AK127 | tgrC1- | tgrC1 | development arrests at loose mound stage | aberrant aggregation | abolished gene expression | increased mound size | decreased gene expression |
AK1521 | tgrC1- | tgrC1 | abolished sporulation | development arrests at loose mound stage | decreased cell motility |
AK1657 | tgrC1-/ (QS38|tgrC1)/ alg9(-19ins) | alg9 | tgrC1 | delayed development | decreased fruiting body size | decreased sporulation |
AK1661 | tgrC1-/ alg9(-19ins) | alg9 | tgrC1 | delayed development | decreased fruiting body size | decreased sporulation |
DBS0350743 | tgrC1-/ alg9(-19ins)-REMI | alg9 | tgrC1 | decreased sporulation |
DBS0350625 | tgrC1-/ stcA- | stcA | tgrC1 | decreased mound size | delayed development | decreased sporulation |
DBS0350626 | tgrC1-/ stcB- | stcB | tgrC1 | decreased mound size | delayed development | decreased sporulation |
DBS0350627 | tgrC1-/ stcC- | stcC | tgrC1 | aberrant stream morphology | delayed development | decreased fruiting body size | decreased sporulation |
AK244 | tipA- | tipA | increased number of tip-organizers | increased mound size | development arrests at mound stage | decreased prestalk gene expression |
JS64 | tipA-/ tipB-/ [act15]: lacZ | tipA | tipB | increased mound size | increased number of mound tips | development arrests at mound stage |
JS98 | tipA-/ tipC-/ [ecmA]: lacZ | tipA | tipC | development arrests at loose mound stage |
JS128 | tipA-/ tipD-/ [ecmA]: lacZ | tipA | tipD | development arrests at loose mound stage |
DBS0351500 | tipB- | tipB | increased number of mound tips |
JS56 | tipB- | tipB | increased number of tip-organizers | increased mound size | increased number of mound tips | development arrests at mound stage |
JS99 | tipB-/ tipC-/ [ecmA]: lacZ | tipB | tipC | increased number of mound tips | development arrests at tipped mound stage |
JS129 | tipB-/ tipD-/ [ecmA]: lacZ | tipB | tipD | increased number of mound tips | development arrests at tipped mound stage |
JS55 | tipC- | tipC | increased number of tip-organizers | increased mound size | development arrests at mound stage | decreased number of autophagosomes | decreased autophagy |
DBS0350729 | tipC-/ [unk]: tipC(2725-3848): GFP | tipC | decreased fruiting body size |
JS130 | tipC-/ tipD-/ [ecmA]: lacZ | tipC | tipD | development arrests at loose mound stage |
JS93 | tipD- | tipD | increased number of tip-organizers | increased mound size | development arrests at mound stage | aberrant vacuole organization | decreased autophagy |
DBS0350730 | tipD- | tipD | decreased pinocytosis | increased cell death | decreased spore germination | decreased catalytic activity | increased gene expression | increased number of mound tips | increased protein modification | aberrant phagosome maturation | aberrant slug development | aberrant fruiting body morphogenesis | abolished protein localization to autophagosome |
DBS0304519 | tirA- | tirA | decreased response to Gram-negative bacterium | decreased defense response to Gram-negative bacterium | aberrant defense response to bacterium | decreased growth rate | aberrant phagocytosis | aberrant vegetative growth |
YLD31A | tlp2- | tlp2 | decreased growth rate |
DBS0236016 | tmcB-/ V12 | tmcB | decreased macrocyst size | aberrant macrocyst formation |
DBS0236018 | tmcC-/ V12 | tmcC | aberrant macrocyst formation |
DBS0351084 | tnlA/ tnlB-REMI | tnlA | tnlB | decreased gene expression | delayed aggregation | increased cell-substrate adhesion | decreased cell motility | increased protein kinase activation |
DBS0350285 | tom1- | tom1 | decreased rate of endocytosis |
DBS0237017 | torA- | torA | delayed aggregation | decreased growth rate | decreased cell motility | decreased chemotaxis rate |
DBS0237018 | torA-/ [act15]: torA: GFP | torA | abolished vegetative growth |
DBS0351498 | tpc2- | tpc2 | increased number of autophagosomes | increased gene expression | decreased gene expression | aberrant vegetative growth | aberrant calcium-mediated signaling | increased protein kinase activity | delayed development | increased lysosomal pH |
DBS0350506 | tpp1- | tpp1 | aberrant response to chemical |
DBS0350504 | tpp1- | tpp1 | increased autophagic cell death | decreased catalytic activity | aberrant response to chemical | aberrant cell morphology | precocious development | decreased sporulation |
DBS0350505 | tpp1-/ [cotB]: tpp1 | tpp1 | wild type |
DBS0350507 | tpp1-/ stpA- | stpA | tpp1 | wild type |
DBS0351017 | tpp1F- | tpp1F | wild type |
DBS0351558 | tpt1- | tpt1 | decreased spore germination | decreased gene expression | decreased growth rate | aberrant cytokinesis | decreased number of mounds | decreased macropinocytosis | delayed development | aberrant fruiting body morphogenesis | increased prestalk cell differentiation |
DBS0351265 | trfA- | trfA | aberrant aggregation | aberrant vegetative growth | decreased chemotaxis to cAMP |
DBS0237924 | triA- | triA | decreased cell-cell adhesion | increased stalk width | increased number of mounds | decreased spore germination | aberrant upper cup formation | aberrant cell motility | aberrant stream morphology | decreased spore size | decreased cell fate determination | aberrant late culminant morphology |
DBS0237996 | triA- | triA | aberrant late culminant morphology |
DBS0237997 | triA- | triA | aberrant late culminant morphology |
DBS0237998 | triA-/ [act15]: GFP | triA | aberrant late culminant morphology |
DBS0237999 | triA-/ [ecmAO]: lacZ: [ecmAO]: gus | triA | increased prestalk O cell differentiation |
DBS0238001 | triA-/ [psA]: lacZ: [psA]: gus | triA | increased prespore cell differentiation |
DBS0351605 | trm9- | trm9 | decreased protein level |
DBS0350107 | tsc2- | tsc2 | decreased phagocytosis |
DBS0237022 | tsg101- | tsg101 | decreased fruiting body size |
DBS0351612 | tsg101- | tsg101 | aberrant cellular process | decreased protein localization | increased defense response to Gram-positive bacterium |
DBS0350816 | tspC- | tspC | aberrant response to osmotic stress |
HM1725 | tstD- | tstD | decreased growth rate | decreased plasma membrane organization | increased growth rate |
DBS0302370 | tsuA- | tsuA | increased oscillatory cAMP signaling | abolished establishment of cell polarity | aberrant chemotaxis to folate | aberrant chemotaxis to cAMP | delayed aggregation | decreased mound size | decreased fruiting body size | aberrant pseudopodium formation |
DBS0302383 | tsuA-/ [unk]: tsuA(1-1774): YFP | tsuA | abolished protein localization to microtubules | abolished protein localization to microtubule organizing center | decreased mound size | decreased fruiting body size |
DBS0302385 | tsuA-/ [unk]: tsuA(1-260): YFP | tsuA | abolished protein localization to microtubules | abolished protein localization to microtubule organizing center | decreased mound size | decreased fruiting body size |
DBS0302384 | tsuA-/ [unk]: tsuA(1774-2247): YFP | tsuA | abolished protein localization to microtubules | abolished protein localization to microtubule organizing center | decreased mound size | decreased fruiting body size |
DBS0302382 | tsuA-/ [unk]: tsuA(K34R): YFP | tsuA | decreased mound size | decreased fruiting body size |
DBS0302381 | tsuA-/ [unk]: tsuA: YFP | tsuA | wild type |
DBS0237024 | ubcB- | ubcB | increased number of tip-organizers | development arrests at mound stage |
DBS0306165 | ube2t- | ube2t | decreased resistance to cisplatin |
DBS0237025 | ubpA- | ubpA | decreased gene expression | decreased chemotaxis rate | abolished aggregation |
DBS0237026 | ubpB- | ubpB | aberrant sorus morphology | increased prestalk gene expression | decreased prespore gene expression | precocious development |
DBS0351464 | uduB-/ AX3 | uduB | increased prestalk cell differentiation |
DBS0237027 | ufc1- | ufc1 | wild type |
DBS0237028 | ugpB-/ DH1 | ugpB | abolished sporulation | decreased glycogen level | aberrant cell differentiation | decreased fruiting body size | delayed culmination |
DBS0266763 | ugpB-/ DH1 | ugpB | decreased stalk length |
DBS0266764 | ugpB-/ HMX | ugpB | abolished cellulose biosynthesis | decreased autophagic vacuole organization | aberrant cell morphology |
DBS0350591 | uppA- | uppA | decreased catalytic activity |
DBS0237031 | vacA- | vacA | wild type |
DBS0351567 | vacA- | vacA | decreased phagocytosis |
DBS0351571 | vacA-/ vacB-/ vacC- | vacA | vacB | vacC | decreased cell-substrate adhesion | decreased gene expression | decreased phagocytosis | aberrant phagosome maturation | decreased protein localization | aberrant protein localization |
DBS0237032 | vacB- | vacB | decreased exocytosis | increased defense response to bacterium |
DBS0351568 | vacB- | vacB | decreased phagocytosis |
DBS0351570 | vacB-/ vacC- | vacB | vacC | decreased phagocytosis |
DBS0351569 | vacC- | vacC | decreased phagocytosis |
DBS0237034 | vasP- | vasP | abolished filopodium formation |
DBS0237035 | vasP- | vasP | decreased lateral pseudopodium retraction | decreased cell-substrate adhesion | decreased vegetative cell size | decreased cell motility | decreased chemotaxis rate | aberrant hyperosmotic response | aberrant actin filament organization | decreased chemotaxis to cAMP | abolished filopodium formation | decreased filopodium formation |
DBS0237033 | vasP-/ [act15]: GFP: vasP(1-264/ 285-380) | vasP | abolished filopodium formation |
DBS0237836 | vasP-/ [act15]: YFP: wipA | vasP | wipA | decreased filopodium formation |
DBS0237842 | vasP-/ [act15]: YFP: wipA/ [act15]: vasP: FLAG | vasP | wipA | increased filopodium formation |
DBS0351313 | vasP-/ [act15]: abpB(129-295) | abpB | vasP | aberrant cellular process |
DBS0351300 | vasP-/ [act15]: eYFP: vasP(S141A) | vasP | decreased protein localization to cell cortex | wild type | decreased lateral pseudopodium retraction | decreased establishment of cell polarity | aberrant actin filament organization |
DBS0351301 | vasP-/ [act15]: eYFP: vasP(S141D) | vasP | aberrant hyperosmotic response | decreased filopodium formation |
DBS0237036 | vasP-/ [act15]: myr: vasP | vasP | increased filopodium formation | aberrant cytokinesis | increased actin filament polymerization |
DBS0237040 | vasP-/ [act15]: vasP | vasP | decreased filopodium formation |
DBS0237840 | vasP-/ [act15]: vasP | vasP | increased filopodium formation | increased actin filament polymerization |
DBS0237037 | vasP-/ [act15]: vasP(1-110: 231-380) | vasP | aberrant cytokinesis | increased actin filament polymerization | decreased filopodium formation |
DBS0237038 | vasP-/ [act15]: vasP(1-228) | vasP | decreased filopodium formation |
DBS0237039 | vasP-/ [act15]: vasP(111-380) | vasP | increased filopodium formation | increased actin filament polymerization |
DBS0350466 | vasP-/ [unk]: vasP(1-197: 221-380) | vasP | wild type |
DBS0350467 | vasP-/ [unk]: vasP(1-261: 285-380) | vasP | decreased cell motility | abolished filopodium formation |
DBS0351536 | vasP-/ hspc300- | hspc300 | vasP | development arrests at slug stage | aberrant sorocarp development |
DBS0351537 | vasP-/ pirA- | pirA | vasP | increased number of mound tips |
DBS0350602 | vilA- | vilA | decreased chemotaxis to cAMP | decreased phototaxis |
DBS0236058 | vmp1- | vmp1 | aberrant aggregation | decreased exocytosis | increased cell death | aberrant autophagy | decreased gene expression | decreased growth rate | aberrant hypotonic response | decreased macropinocytosis | aberrant vacuole organization | aberrant protein localization to autophagosome | aberrant protein localization | aberrant signal transduction |
DBS0351250 | vmp1-/ [act15]: vmp1(G268L): GFP | vmp1 | aberrant aggregation | aberrant protein localization to autophagosome |
DBS0350873 | vps13F- | vps13F | aberrant defense response to bacterium | decreased growth rate |
DG1118 | vps46- | vps46 | increased sorus size |
DBS0237046 | vwkA- | vwkA | increased myosin II assembly | decreased growth rate | aberrant cytokinesis | aberrant contractile vacuole morphology | aberrant hypotonic response | delayed development | increased protein level | aberrant fruiting body morphogenesis | decreased contractile vacuole discharge |
DBS0350290 | vwkA-/ [act15]: GFP: mhcA | mhcA | vwkA | aberrant myosin II filament organization |
TL61 | wacA- | wacA | wild type |
TL99 | wacA- | wacA | wild type |
DBS0237048 | warA- | warA | development arrests at slug stage | increased basal disc size | decreased prespore cell differentiation | increased prestalk O cell differentiation |
DBS0237049 | warA- | warA | development arrests at slug stage | increased basal disc size | decreased prespore cell differentiation | increased prestalk O cell differentiation |
DBS0237050 | warA-/ hbx2- | hbx2 | warA | increased basal disc size | development arrests at mound stage | decreased prespore cell differentiation | increased prestalk O cell differentiation |
DBS0237051 | wasA- | wasA | decreased cell motility | delayed development | aberrant actin filament organization |
DBS0351506 | wasA- | wasA | aberrant protein localization to trailing edge |
DBS0351509 | wasA-/ [tet]: scrA/ [unk]: GFP: wasA(I173A/ F179A) | scrA | wasA | aberrant pseudopodium formation |
DBS0351508 | wasA-/ [unk]: GFP: wasA(I173A/ F179A) | wasA | aberrant protein localization to trailing edge | decreased establishment of cell polarity |
DBS0237052 | wasA1-/ [tet]: YFP: wasA2 | wasA | decreased actin filament polymerization | abolished positive chemotaxis | abolished aggregation | aberrant actin filament organization |
DBS0237812 | wasA1-/ [tet]: YFP: wasA2/ [act15]: wasA | wasA | increased actin filament polymerization at leading edge |
DBS0237811 | wasA1-/ [tet]: YFP: wasA2/ [act15]: wasA(Y33A/ W39A/ F90A/ F91A) | wasA | decreased actin filament polymerization | decreased actin filament polymerization at leading edge |
DBS0237820 | wasA1-/ [tet]: YFP: wasA2/ [act15]: wipA | wasA | wipA | abolished positive chemotaxis |
DBS0350254 | wasB- | wasB | abolished protein localization to cytoplasmic vesicle | aberrant chemotaxis to cAMP | increased actin filament polymerization | increased protein level | aberrant pseudopodium formation |
DBS0350255 | wasB-/ [act15]: YFP: wasB | wasB | wild type |
DBS0351525 | wasC- | wasC | increased actin filament polymerization | decreased phagocytosis | increased cell-substrate adhesion | decreased chemotaxis rate |
DBS0350239 | washc5- | washc5 | abolished exocytosis | decreased protein level | decreased growth rate | decreased phagocytosis | aberrant endosome morphology | decreased vegetative cell size | abolished phagosome reneutralization | decreased secretion of lysosomal enzymes | abolished actin filament polymerization | aberrant lysosome organization |
DBS0351185 | washc5-/ [act15]: washc5(N457D): GFP | washc5 | abolished exocytosis |
DG1053 | wimA- | wimA | aberrant fruiting body morphogenesis |
DG1064 | wimA- | wimA | aberrant fruiting body morphogenesis |
DBS0349863 | wshA- | wshA | increased protein localization | abolished exocytosis | decreased defense response to Gram-negative bacterium | decreased macroautophagy | abolished endocytic recycling | aberrant vegetative growth | decreased phagocytosis | decreased protein processing in phagocytic vesicle | aberrant phagosome maturation | abolished phagosome reneutralization | decreased secretion of lysosomal enzymes | increased defense response to Gram-positive bacterium | decreased protein localization | aberrant lysosome organization | aberrant protein localization |
DBS0350872 | wshA-/ [act15]: GFP: wshA/ [act15]: vatB: RFP | vatB | wshA | abolished endocytic recycling |
DBS0350451 | wshA-/ atg1- | atg1 | wshA | wild type |
DBS0350248 | wshA-/ fam21-/ [act15]: GFP: fam21 | fam21 | wshA | abolished actin filament polymerization |
DBS0350247 | wshA-/ fam21-/ [act15]: GFP: wshA | fam21 | wshA | aberrant lysosome organization |
DBS0350943 | xacA- | xacA | decreased hypotonic response | aberrant contractile vacuole morphology | aberrant actin filament organization |
DBS0350950 | xacA- | xacA | increased lateral pseudopodium formation | decreased chemotaxis to cAMP | aberrant actin filament organization |
DBS0350944 | xacA-/ [act15]: xacA(1-320) | xacA | decreased growth rate | aberrant cytokinesis |
DBS0350945 | xacA-/ [act15]: xacA(779-1335) | xacA | decreased hypotonic response | aberrant contractile vacuole morphology |
HM1456 | xpc- | xpc | wild type | aberrant vegetative growth |
HM1403 | xpf- | xpf | aberrant vegetative growth | decreased resistance to cisplatin |
AK235 | yakA- | yakA | abolished aggregation |
AK800 | yakA- | yakA | decreased protein localization to cell cortex | decreased gene expression | aberrant cell cycle | increased cellular thermotolerance | aberrant gene expression | decreased protein kinase activation | abolished aggregation | aberrant response to oxidative stress | aberrant cellular response to stress | decreased cAMP level |
DBS0237087 | yakA-/ AX3 | yakA | decreased growth rate | abolished aggregation | abolished actin filament polymerization | decreased cGMP biosynthesis |
DBS0237091 | yakA-/ [crlA]: crlA | crlA | yakA | abolished vegetative growth |
DBS0350058 | yakA-/ keaA- | keaA | yakA | wild type |
DBS0351199 | yakA-/ pkaC- | pkaC | yakA | aberrant cellular response to stress |
AK804 | yakA-/ pufA- | pufA | yakA | increased protein kinase activity | increased protein level | aberrant fruiting body morphogenesis | increased growth rate | precocious development |
DBS0350898 | yelA-/ AX2 | yelA | precocious prestalk gene expression | increased basal disc size |
DG1014 | yelA-/ AX4 | yelA | aberrant spore morphology | precocious sporulation | development arrests at mound stage | aberrant mound color | aberrant sporulation |
DBS0349797 | zak2- | zak2 | decreased prespore gene expression | decreased protein kinase activation | aberrant fruiting body morphogenesis | decreased sporulation |
DBS0349883 | zak2-/ [act15]: GFP | zak2 | decreased sporulation |
DBS0349798 | zak2-/ [ecmA]: LacZ | zak2 | aberrant prestalk gene expression |
DBS0349882 | zak2-/ [ecmA]: zakA | zak2 | zakA | precocious prestalk gene expression |
ARK100-110 | zakA- | zakA | abolished stream development | decreased protein kinase activity | increased prestalk gene expression | decreased prespore gene expression | aberrant fruiting body morphogenesis | decreased chemotaxis to cAMP | delayed culmination | decreased sporulation |
DBS0238142 | zakA- | zakA | development arrests at tipped mound stage |
DBS0349803 | zakA-/ [ecmB]: LacZ | zakA | aberrant prestalk gene expression |
DG1050 | zipA- | zipA | decreased fruiting body size |
DBS0350068 | zizB- | zizB | aberrant fruiting body morphogenesis | delayed development | decreased chemotaxis to cAMP |
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